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| 1 | Long-term prognostic impact of circulating tumour cells in gastric cancer patients显示文摘AIM To analyse the long-term prognostic impact of circulating tumour cells(CTCs) in gastric cancer patients who underwent surgery. METHODS A 7.5-m L peripheral vein blood sample was obtained from each patient with treatment-negative gastric adenocarcinoma before surgery. OBP-401, a telomerasespecific, replication-selective, oncolytic adenoviral agent carrying the green fluorescent protein gene, was used to label CTCs. Correlations between the number of CTCs and clinical end points were evaluated. RESULTS The median follow-up period of the surviving patients with gastric cancer was 60 mo. The CTC number tended to increase concomitantly with disease progression. The overall survival of patients with more than five CTCs in 7.5-m L of peripheral blood was lower than that of patients with five or less CTCs, although the difference was not significant(P = 0.183). A significant difference in relapse-free survival was found between patients with more than five and those with five or less CTCs(P = 0.034).CONCLUSION A lower number of CTCs was correlated with higher relapse-free survival rates in patients. Detection of CTCs using OBP-401 may be useful for predicting prognosis in gastric cancer. | Hiroaki Ito Jun Sato Yukio Tsujino Noriko Yamaguchi Satoshi Kimura Keigo Gohda Katsuhiro Murakami Manabu Onimaru Tohru Ohmori Fumihiro Ishikawa Haruhiro Inoue | 2016 | World Journal of Gastroenterology2016，22，46： | 8 |
| 2 | A New Thoracic Reconstruction Technique “Transforaminal Thoracic Interbody Fusion”: A Preliminary Report of Clinical Outcomes显示文摘 | Masaaki Machino Yasutsugu Yukawa Keigo Ito Hiroaki Nakashima Fumihiko Kato | 2010 | Spine2010，，19： | 2 |
| 3 | Cervical Alignment and Range of Motion After Laminoplasty: Radiographical Data From More Than 500 Cases With Cervical Spondylotic Myelopathy and a Review of the Literature显示文摘 | Masaaki Machino Yasutsugu Yukawa Tetsuro Hida Keigo Ito Hiroaki Nakashima Shunsuke Kanbara Daigo Morita Fumihiko Kato | 2012 | Spine2012，，20： | 1 |
| 4 | Placement and complications of cervical pedicle screws in 144 cervical trauma patients using pedicle axis view techniques by fluoroscope 显示文摘 | Yasutsugu Yukawa Fumihiko Kato Keigo Ito | 2009 | Eur Spine2009，18，： | 1 |
| 5 | The Prevalence of Pre- and Postoperative Symptoms in Patients With Cervical Spondylotic Myelopathy Treated by Cervical Laminoplasty显示文摘 | Masaaki Machino Yasutsugu Yukawa Tetsuro Hida Keigo Ito Hiroaki Nakashima Shunsuke Kanbara Daigo Morita Fumihiko Kato | 2012 | Spine2012，，22： | 1 |
| 6 | Cervical Alignment and Range of Motion After Laminoplasty: Radiographical Data From More Than 500 Cases With Cervical Spondylotic Myelopathy and a Review of the Literature显示文摘 | Masaaki Machino Yasutsugu Yukawa Tetsuro Hida Keigo Ito Hiroaki Nakashima Shunsuke Kanbara Daigo Morita Fumihiko Kato | 2012 | Spine2012，，20： | 1 |
| 7 | The Prognostic Nutritional Index Predicts Long-term Outcomes of Gastric Cancer Patients Independent of Tumor Stage显示文摘 | Kazuhiro Migita Tomoyoshi Takayama Keigo Saeki Sohei Matsumoto Kohei Wakatsuki Koji Enomoto Tetsuya Tanaka Masahiro Ito Norio Kurumatani Yoshiyuki Nakajima | 2013 | Annals of Surgical Oncology2013，，8： | 1 |
| 8 | Persistent Physical Symptoms After Laminoplasty: Analysis of Postoperative Residual Symptoms in 520 Patients With Cervical Spondylotic Myelopathy显示文摘 | Masaaki Machino Yasutsugu Yukawa Tetsuro Hida Keigo Ito Hiroaki Nakashima Shunsuke Kanbara Daigo Morita Fumihiko Kato | 2012 | Spine2012，，11： | 1 |
| 9 | Can Elderly Patients Recover Adequately After Laminoplasty? A Comparative Study of 520 Patients With Cervical Spondylotic Myelopathy显示文摘 | Masaaki Machino Yasutsugu Yukawa Tetsuro Hida Keigo Ito Hiroaki Nakashima Shunsuke Kanbara Daigo Morita Fumihiko Kato | 2012 | Spine2012，，8： | 1 |
| 10 | Is Decompressive Surgery Effective for Spinal Cord Sarcoidosis Accompanied With Compressive Cervical Myelopathy?显示文摘 | Yoshihito Sakai Yukihiro Matsuyama Shiro Imagama Zenya Ito Norimitsu Wakao Naoki Ishiguro Hirohisa Watanabe Fumihiko Kato Yasutsugu Yukawa Keigo Ito Kazuhiro Suzuki Akiko Tsuboi Tokumi Kanemura Go Yoshida | 2010 | Spine2010，，23： | 1 |
| 11 | Prognostic value of post-treatment ^(18)F-FDG PET/CT for advanced head and neck cancer after combined intra-arterial chemotherapy and radiotherapy显示文摘Objective:To clarify the prognostic value of post-treatment 18F-fluorodeoxyglucose(FDG) positron emission tomography(PET)/computed tomography(CT) in patients with advanced head and neck squamous cell carcinoma(HNSCC) after combined intra-arterial chemotherapy and radiotherapy(IACR).Methods:Thirty-six patients with HNSCC who underwent IACR were recruited.The period from the end of IACR to the last post-treatment 18F-FDG PET/CT examination was 8-12 weeks.Both patient-based and lesion-based analyses were used to evaluate the PET/CT images.For lesion-based analysis,36 regions(12 lesions of recurrences and 24 scars at primary sites) were selected.The Kaplan-Meier method was used to assess the overall survival(OS) stratified by 18F-FDG uptake or visual interpretation results.Results:Twelve patients with recurrence were identified by six months after IACR.The sensitivity and specificity in the patient-based analysis were 67%(8/12) and 88%(21/24),respectively.The mean OS was estimated to be 12.1 months(95% CI,6.3-18.0 months) for the higher maximum standardized uptake value(SUVmax) group(n=7) and 44.6 months(95% CI,39.9-49.3 months) for the lower SUVmax group(n=29).OS in the higher SUVmax group(cut-off point,6.1) or positive visual interpretation group was significantly shorter than that in the lower SUVmax or negative visual interpretation group(P<0.001 and P<0.05,respectively).Conclusions:The SUVmax and visual interpretation of HNSCC on post-IACR 18F-FDG PET/CT can provide prognostic survival estimates. | Kimiteru Ito Keigo Shimoji Yoko Miyata Kouhei Kamiya Ryogo Minamimoto Kazuo Kubota Momoko Okasaki Miyako Morooka Jyunkichi Yokoyama | 2014 | Chinese Journal of Cancer Research2014，26，1： | 1 |
| 12 | Marked decrease in serum pepsinogen II levels resulting from endoscopic resection of a large duodenal tumor显示文摘 | Tomoyuki Yada Koichi Ito Keigo Suzuki Koki Okubo Yoichiro Aoki Naoki Akazawa Hitohiko Koizuka Tsuyoshi Ishida Naomi Uemura | 2014 | Clinical Journal of Gastroenterology2014，，6： | 1 |
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