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| 1 | A high-density microsatellite consensus map for bread wheat ( Triticum aestivum L.)显示文摘 | Daryl J. Somers Peter Isaac Keith Edwards | 2004 | Theoretical and Applied Genetics2004，，6： | 3 |
| 2 | Stratification of outcomes for mucinous appendiceal adenocarcinoma with peritoneal metastasis by histological grade显示文摘AIM To investigate the importance of a three-tiered histologic grade on outcomes for patients with mucinous appendiceal adenocarcinoma(MAA).METHODS Two hundred and sixty-five patients with MAA undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy were identified from a prospective database from 2004 through 2014. All pathology was reviewed by our gastrointestinal subspecialty pathologists and histological grade was classified as well-differentiated, moderately differentiated, and poorly differentiated. Survival analysis was performed using Cox proportional hazards regression.RESULTS There were 201(75.8%) well-, 45(16.9%) moderatelyand 19(7.2%) poorly-differentiated tumors. Histological grade significantly stratified the 5-year overall survival(OS), 94%, 71% and 30% respectively(P < 0.001) as well as the 5-year disease-free survival(DFS) 66%, 21% and 0%, respectively(P < 0.001). Independent predictors of DFS included tumor grade(HR = 1.78, 95%CI: 1.21-2.63, P = 0.008), lymph node involvement(HR = 0.33, 95%CI: 0.11-0.98, P < 0.02), previous surgical score(HR = 1.31, 95%CI: 1.1-1.65, P = 0.03) and peritoneal carcinomatosis index(PCI)(HR = 1.05, 95%CI: 1.02-1.08, P = 0.002). Independent predictors of OS include tumor grade(HR = 2.79, 95%CI: 1.26-6.21, P = 0.01), PCI(HR = 1.10, 95%CI: 1.03-1.16, P = 0.002), and complete cytoreduction(HR = 0.32, 95%CI: 0.11-0.92, P = 0.03). Tumor grade and PCI were the only independent predictors of both DFS and OS. Furthermore, histological grade and lymphovascular invasion stratified the risk of lymph node metastasis into a low(6%) and high(40%) risk groups. CONCLUSION Our data demonstrates that moderately differentiated MAA have a clinical behavior and outcome that is distinct from well-and poorly-differentiated MAA. The threetier grade classification provides improved prognostic stratification and should be incorporated into patient selection and treatment algorithms. | Travis Edward Grotz Richard E Royal Paul F Mansfield Michael James Overman Gary N Mann Kristen Ashlee Robinson Karen A Beaty Safiea Rafeeq Auerlio Matamoros Michelle W Taggart Keith Francis Fournier | 2017 | World Journal of Gastrointestinal Oncology2017，9，9： | 2 |
| 3 | A high-density microsatellite consensus map for bread wheat (Triticum aestivum L.)显示文摘 | Daryl J. Somers Peter Isaac Keith Edwards | 2004 | Theoretical and Applied Genetics2004，，6： | 2 |
| 4 | Disruption of the developmental programme of Trypanosoma brucei by genetic ablation of TbZFP1, a differentiation‐enriched CCCH protein显示文摘 | Edward F.Hendriks Keith R.Matthews | 2005 | Molecular Microbiology2005，，： | 2 |
| 5 | Efficacy and safety of sitagliptin added to ongoing metformin and rosiglitazone combination therapy in a randomized placebo‐controlled 54‐week trial in patients with type 2 diabetes (一项为期54周的对持续使用二甲双胍与罗格列酮联合治疗的2型糖尿病患者加用西格列汀治疗的有效性与安全性的随机安慰剂对照研究)*显示文摘 | Adrian S. DOBS Barry J. GOLDSTEIN Pablo ASCHNER Edward S. HORTON Guillermo E. UMPIERREZ Lorraine DURAN Julie S. HILL Yu CHEN Gregory T. GOLM Ronald B. LANGDON Debora E. WILLIAMS‐HERMAN Keith D. KAUFMAN John M. AMATRUDA Juan Camilo ARJONA FERREIRA | 2013 | Journal of Diabetes2013，，1： | 1 |
| 6 | A high-density micosatellite consensus map for bread wheat显示文摘 | Dary J Samers Perter Isaac Keith Edwards | 2004 | Theor Appl Genet2004，109，： | 1 |
| 7 | Gene expression in giant-celltumors显示文摘 | Keith M S Edward Y C Denis R C | 2004 | J Biotechno2004，114，1： | 1 |
| 8 | Ursodeoxycholic acid as a chemopreventive agent in patients with ulcerative colitis and primary sclerosing cholangitis显示文摘 | Darrell S. Pardi Edward V. Loftus Walter K. Kremers Jill Keach Keith D. Lindor | 2003 | Gastroenterology2003，，4： | 1 |
| 9 | The ratio of the arithmetic to the geometric mean : A first- order statistical test for muhilook SAR image homogeneity 显示文摘 | Martio Beauchemin Keith P B Thomson Geoffrey Edwards | 1996 | IEEE Trans Geosci Remote Sens1996，34，2： | 1 |
| 10 | Optimisation of a Microsatellite Enrichment Technique in Saccharum spp.显示文摘 | Giovanni M. Cordeiro Tina L. Maguire Keith J. Edwards Robert J. Henry | 1999 | Plant Molecular Biology Reporter1999，，3： | 1 |
| 11 | Microbial contributions to the aggregation of a cultivated grassland soil amended with starch显示文摘 | Georg Guggenberger Edward T Elliott Serita D Frey Johan Six Keith Paustian | 1999 | Soil Biology and Biochemistry1999，，3： | 1 |
| 12 | Modulation of the inflammatory response and apoptosis using epidermal growth factor and hepatocyte growth factor in a liver injury model: a potential approach to the management and treatment of cholestatic liver disease显示文摘 | Keith A. Thatch Marshall Z. Schwartz Edward Y. Yoo Kim G. Mendelson Duane S. Duke | 2008 | Journal of Pediatric Surgery2008，，12： | 1 |
| 13 | Plant growth and microbial processes in a constructed wetland planted with Phalaris arundinacea显示文摘 | Keith R. Edwards Hana ?i?ková Kate?ina Zemanová Hana ?antr??ková | 2006 | Ecological Engineering2006，，2： | 1 |
| 14 | Plant growth and microbial processes in a constructed wetland planted with Phalaris arundinacea显示文摘 | Keith R Edwards Hana Cizkova | 2006 | Ecological Engineering2006，27，： | 1 |
| 15 | Microbial contributions to the aggregation of a cultivated grassland soil amended with starch显示文摘 | Georg Guggenberger Edward T Elliott Serita D Frey Johan Six Keith Paustian | 1999 | Soil Biology and Biochemistry1999，，3： | 1 |
| 16 | Anemia Management and Association of Race With Mortality and Hospitalization in a Large Not-for-Profit Dialysis Organization显示文摘 | Karen S. Servilla Ajay K. Singh William C. Hunt Antonia M. Harford Dana Miskulin Klemens B. Meyer Edward J. Bedrick Mark R. Rohrscheib Antonios H. Tzamaloukas H. Keith Johnson Philip G. Zager | 2009 | American Journal of Kidney Diseases2009，，3： | 1 |
| 17 | A high-density microsatellite consensus map for bread wheat (Triticum aestivum L.)显示文摘 | Daryl J. Somers Peter Isaac Keith Edwards | 2004 | Theoretical and Applied Genetics2004，，6： | 1 |
| 18 | A high-density microsatellite consensus map for bread wheat (Triticum aestivum L.)显示文摘 | Daryl J. Somers Peter Isaac Keith Edwards | 2004 | Theoretical and Applied Genetics2004，，6： | 1 |
| 19 | A critical review of aluminum anode activation, dissolution mechanisms and performance 显示文摘 | Edward L William H H Keith E L | 2001 | Corrosion2001，，： | 1 |
| 20 | A comparison of the electrodynamics of metals under the action of large electric currents显示文摘 | Michael E. Baginski Edward C. Shaffer Keith A. Thomas Jeffrey S. McGuirk | 2000 | International Journal of Applied Electromagnetics and Mechanics2000，，2： | 1 |
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