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| 1 | Effects of Sb,Sm, and Sn additions on the microstructure and mechanical properties of Mg-6Al-1.2Y-0.9Nd alloy显示文摘The microstructure and mechanical properties of Mg-6Al-1.2Y-0.9Nd magnesium alloy with Sb, Sm, or Sn addition were investigated through X-ray diffraction (XRD), optical microscopy (OM), scanning electron microscopy (SEM), and energy dispersive spectroscopy (EDS). The results show that small amounts of Sb, Sm, and especially Sn can refine the grains of the alloy. High melting point Sb3Y5, Al2Sm, and Nd5Sn3 intermetallic compounds can be formed respectively when Sb, Sm, and Sn are added to the alloy. Sb and Sm can improve the tensile strength of the alloy at ambient and elevated temperatures. The tensile strength of the alloy with Sm addition is the highest at 293 and 423 K. However, the tensile strength of the alloy with Sn addition is the highest at 448 K. | LI Kejie LI Quanan JING Xiaotian CHEN Jun ZHANG Xingyuan | 2009 | Rare Metals2009，28，5： | 39 |
| 2 | Roles and mechanisms of ginsenoside in cardiovascular diseases: progress and perspectives显示文摘Ginseng is among the oldest traditional Chinese medicinal herbs and is widely used in China and Southeast Asia. Over the past 50 years, considerable research has focused on the chemical constituents, pharmacological action, and clinical applications of ginseng. In this review, we examine the current state of research on ginseng, including the main active ingredient ginsenoside, its pharmacological effects on the cardiovascular system, and mechanisms of action. We focus on what is known of the effects of ginseng against atherosclerosis, arrhythmia, myocardial ischemia, and its inhibition of ventricular remodeling, providing a basis for expanding the clinical applications of ginseng. | Yingying Sun Yue Liu Keji Chen | 2016 | Science China(Life Sciences)2016，59，3： | 20 |
| 3 | Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition显示文摘尽管在基因倡导者区域的 DNA methylation 的函数很好在 transcriptional 压抑被建立,在基因身体区域的 DNA methylation 的 evolutionarily 保存的普遍分发的函数仍然保持不完全地理解。这里,我们证明 DNA methylation 在包括的或者拼接的 exons (ASEs ) 被充实,并且 DNA methylation 的那抑制导致 ASEs 的异常拼接。methyl-CpG-binding 蛋白质 MeCP2 在包括的 ASEs 被充实,特别地也是的那些高度, DNA methylation 的 methylated,和抑制破坏到 exons 的 MeCP2 的特定的指向。有趣地, MeCP2 的脱离导致增加的 histone acetylation 和异常跳过 ASE 事件。我们进一步显示出那显示出的活动导致 exon 跳过的 histone deacetylase (HDAC ) 的那抑制有那的重叠的高度重要的度由 MeCP2 引起了击倒。一起,我们的数据显示 DNA methylation 在 exon 定义操作调制拼接的其他的 RNA 的那 intragenic 并且能经由多功能的蛋白质 MeCP2 的招募提高 exon 识别,它从而通过 HDAC 的随后的招募维持本地 histone hypoacetylation。 | Alika K Maunake Iouri Chepelev Kairong Cui Keji Zhao | 2013 | Cell Research2013，23，11： | 19 |
| 4 | Platelet proteomics and its advanced application for research of blood stasis syndrome and activated blood circulation herbs of Chinese medicine显示文摘The development of novel and efficient antiplatelet agents that have few adverse effects and methods that improve antiplatelet resistance has long been the focus of international research on the prevention and treatment of cardiovascular and cerebrovascular diseases.Recent advances in platelet proteomics have provided a technology platform for high-quality research of platelet pathophysiology and the development of new antiplatelet drugs.The study of blood stasis syndrome(BSS)and activated blood circulation of traditional Chinese medicine(TCM)is one of the most active fields where the integration of TCM and western medicine in China has been successful.Activated blood circulation herbs(ABC herbs)of Chinese medicine are often used in the treatment of BSS.Most ABC herbs have antiplatelet and anti-atherosclerosis activity,but knowledge about their targets is lacking.Coronary heart disease(CHD),BSS,and platelet activation are closely related.By screening and identifying activated platelet proteins that are differentially expressed in BSS of CHD,platelet proteomics has helped researchers interpret the antiplatelet mechanism of action of ABC herbs and provided many potential biomarkers for BSS that could be used to evaluate the clinical curative effect of new antiplatelet drugs.In this article the progress of platelet proteomics and its advanced application for research of BSS and ABC herbs of Chinese medicine are reviewed. | LIU Yue YIN HuiJun CHEN KeJi | 2013 | Science China(Life Sciences)2013，56，11： | 14 |
| 5 | Dynamic regulation of alternative splicing and chromatin structure in Drosophila gonads revealed by RNA-seq显示文摘抄写和 post-transcriptional 过程例如其他的拼接,在在 metazoans 控制发展节目起关键作用。最近出现的 RNA-seq 方法把我们真核细胞的 transcriptomes 的理解带到新水平,因为它能两个都同时解决基因表示水平和其他的拼接事件。在性腺获得细胞的区别的更好的理解,我们用 RNA-seq 从果蝇睾丸和卵巢分析了 mRNA 侧面。我们识别了有性特定的 isoforms 在的一套基因野类型(WT ) 性腺,包括几个抄写因素。我们发现从无差别的细菌房间的精子的区别导致了拼接的 RNA 的戏剧的 downregulation 因素。我们的数据证实 RNA 拼接事件是显著地在云石(欺骗) 的无差别的充实房间的袋子里更经常在在 WT 的区别之上的变异的睾丸,而是 downregulated 睾丸。与这一致,我们证明基因在 WT 为成熟分裂和终端区别要求睾丸主要在 transcriptional 水平被调整,然而并非由选择拼接。出人意料地,我们在在无差别的充实房间的欺骗睾丸改变因素和 histone 修改酶的染色质的所有家庭的表示观察了增加。更有趣地,有相反的酶的活动的染色质管理者和 histone 修改酶是在在睾丸的无差别的房间的 coenriched,建议这些房间可以拥有动态染色质建筑学。最后,我们的数据表明果蝇 gonadal transcriptomes 的许多新特征,和愿望导致的更全面的理解微分基因表示并且拼接在果蝇调整 gametogenesis。我们的数据为在果蝇在细菌房间生物学的许多有趣的区域拼接的基因表示和选择的系统的学习提供了一个基础,例如性同种二形和在 germline 干细胞系的增长对终端区别程序的规定的分子的基础。为未加工、分析的 RNA-seq 数据的 GEO 就职数字是 GSE16960。 | Qiang Gan Iouri Chepelev Gang Wei Lama Tarayrah Kairong Cui Keji Zhao Xin Chen | 2010 | Cell Research2010，20，7： | 9 |
| 6 | Notch1 signaling inhibits growth of EC109 esophageal carcinoma cells through downmodulation of HPV18 E6/E7 gene expression显示文摘 | Kejie ZHANG Quan-yi LU Xiao-qing NIU Peng ZHANG Jiang-ning ZHAO Zhao WANG Jia-sheng HU Pu LI Wen-li LIU | 2009 | Acta Pharmacologica Sinica2009，30，2： | 9 |
| 7 | Characteristics of the lower layer of sandstorms in the Minqin desert-oasis zone显示文摘By measuring the sand-dust flux,vertical deposition,and the wind velocity throughout 19 sandstorms in the Minqin region,we quantitatively analyzed the horizontal distribution and vertical variation in sandstorm characteristics under different land cover conditions.The effect of different land cover on mitigating sandstorms was also investigated.The results indicated that,in the surface layer ranging from 0-50 m,the intensity of sand-dust horizontal flux and concentration of sand-dust decreased with the increase of the height in the desert and the edge of oasis,whereas the two physical quantities increased slightly with the increase of the height in the oasis.The two physical quantities obey power function well under all three cover conditions.Moreover,in the desert and at the edge of oasis,the sand-dust vertical deposition decreased with the increase of the height.But a partial unimodal distribution at the oasis site and the maximum deposition occurred at the height of 9 m,which corresponds to the middle height of farmland protection forest.The annual flux that passed through a section of 1 m in width and 50 m in height was 9169 kg in the desert,5318 kg at the edge of oasis,and 2345 kg in the oasis.And the annual fluxes at the edge of oasis and in the oasis are 42% and 74% less,respectively,than that in the desert.This implies that the wind break forest significantly reduced the intensity of sandstorms. | ZHAO Ming ZHAN KeJie YANG ZiHui FANG ErTian QIU GuoYu WANG QiangQiang ZHANG YinChang GUO ShuJiang LI AiDe ZHANG JingChun | 2011 | Science China Earth Sciences2011，54，5： | 8 |
| 8 | ON NON-ISOTROPIC JACOBI PSEUDOSPECTRAL METHOD显示文摘在这篇论文,非各向同性的 Jacobi 假光谱方法被建议,它的应用斧子考虑了。一些结果在上;多维的 Jacobi 高斯类型插值和相关 Bernstein 杰克森类型不平等斧子建立了,它起一个重要作用在假光谱方法。假光谱方法被用于一二 -- 维的单个问题中间 axisymmetric 上的一个问题领域。建议计划的集中被建立。数字结果表明建议方法的效率。 | Benyu Guo Keji Zhang Department of Mathematics,Shanghai Normal University,Shanghai 200234,China Scientific Computing Key Laboratory of Shanghai Universities Division of Computational Science of E-Institute of Shanghai Universities | 2008 | Journal of Computational Mathematics2008，26，4： | 8 |
| 9 | Correlation between platelet gelsolin levels and different types of coronary heart disease显示文摘Gelsolin is an important cytoskeletal protein of platelets and studies have shown a close relationship between gelsolin and cardiovascular disease.However,the role of gelsolin in the development of coronary heart disease(CHD) is unclear.In this study,we record the distribution of gelsolin in human platelets and plasma and its association with different types of CHD.This study included 114 cases,with 33 stable angina pectoris(SAP) cases,81 acute coronary syndrome(ACS) cases—composed of 39 unstable angina pectoris(UAP) and 42 acute myocardial infarction(AMI) cases,and 31 healthy control participants.Gelsolin concentration in platelet rich plasma(PRP) and platelet poor plasma(PPP),actin filament(F-actin) and Gc-globulin of PPP were determined by enzyme-linked immunoadsorbent assay(ELISA).The fluorescence intensity of CD62p and cytoplasmic calcium([Ca2+] i) in human platelets measured by flow cytometry.We also used turbidimetry to detect the platelet aggregation rate(PAR).We analyzed the correlation between platelet gelsolin concentration and CD62p or plasma F-actin levels among each different patient group.Compared with the control group,the gelsolin level in PRP of UAP and AMI groups increased significantly(P<0.01),while the gelsolin level in PPP of all the three patient groups decreased markedly(P<0.01),and the CD62p,PAR,[Ca2+] i of platelets,F-actin and Gc-globulin of the UAP and AMI groups increased significantly(P<0.01).Compared with the SAP group,the gelsolin level in PRP,the PAR,[Ca2+] i of platelets and CD62p of other two groups increased significantly(P<0.01),F-actin of the AMI group increased markedly(P<0.01).Platelet cytoskeleton protein dynamics vary among the different types of CHD.Platelet gelsolin levels are markedly increased and accompanied by increased platelet activity,F-actin and [Ca2+] i of ACS patients,while gelsolin levels in PPP are markedly lower.Abnormally increased platelet gelsolin levels show high positive correlation with the level of platelet activity.Therefore,platelet gelsolin might be a novel molecular marker and/or a new potential therapeutic target of anti-platelet therapy of ACS. | LIU Yue YIN HuiJun JIANG YueRong XUE Mei CHEN KeJi | 2012 | Chinese Science Bulletin2012，57，6： | 8 |
| 10 | Bile acid coordinates microbiota homeostasis and systemic immunometabolism in cardiometabolic diseases显示文摘Cardiometabolic disease(CMD), characterized with metabolic disorder triggered cardiovascular events, is a leading cause of death and disability. Metabolic disorders trigger chronic low-grade inflammation, and actually, a new concept of metaflammation has been proposed to define the state of metabolism connected with immunological adaptations. Amongst the continuously increased list of systemic metabolites in regulation of immune system, bile acids(BAs) represent a distinct class of metabolites implicated in the whole process of CMD development because of its multifaceted roles in shaping systemic immunometabolism. BAs can directly modulate the immune system by either boosting or inhibiting inflammatory responses via diverse mechanisms. Moreover, BAs are key determinants in maintaining the dynamic communication between the host and microbiota. Importantly, BAs via targeting Farnesoid X receptor(FXR) and diverse other nuclear receptors play key roles in regulating metabolic homeostasis of lipids, glucose, and amino acids. Moreover, BAs axis per se is susceptible to inflammatory and metabolic intervention, and thereby BAs axis may constitute a reciprocal regulatory loop in metaflammation. We thus propose that BAs axis represents a core coordinator in integrating systemic immunometabolism implicated in the process of CMD. We provide an updated summary and an intensive discussion about how BAs shape both the innate and adaptive immune system, and how BAs axis function as a core coordinator in integrating metabolic disorder to chronic inflammation in conditions of CMD. | Baoyi Guan Jinlin Tong Haiping Hao Zhixu Yang Keji Chen Hao Xu Anlu Wang | 2022 | Acta Pharmaceutica Sinica B2022，12，5： | 7 |
| 11 | Characterization of genome-wide enhancer-promoter interactions reveals co-expression of interacting genes and modes of higher order chromatin organization显示文摘最近的 epigenomic 研究在人的染色体预言了几千潜在的 enhancers。然而,没有为这些潜在的 enhancers 的目标倡导者的系统的描述。为活跃 enhancers 把 H3K4me2 用作一个标记,我们在人的 CD4 + T 房间识别了染色体宽的 EP 相互作用。在 6 520 个长途的染色质相互作用之中,我们识别 2 067 enhancers 与 1 619 个倡导者一起交往并且提高他们的表示。这些 enhancers 在可存取的染色质区域存在并且与各种各样的 histone 修正和聚合酶 II 绑定被联系。没有交往的 enhancers,有交往的 enhancers 的倡导者比那些在高水平被表示,并且他们的表示层次断然与交往的 enhancers 的数字被相关。有趣地,交往倡导者们以一种织物特定的方式被共同表示。我们也发现染色体被组织成交往的领域的多重层次。我们的结果定义 EP 相互作用的一个全球看法并且提供一个数据集合进一步理解 enhancer 指向和远程的染色质组织的机制。为未加工、分析的染色质相互作用数据的基因表示选集就职数字是 GSE32677。 | Iourl Chepelev Gang Wei Dara Wangsa Qingsong Tang Keji Zhao | 2012 | Cell Research2012，22，3： | 6 |
| 12 | Microstructure and mechanical properties of Mg-6Al magnesium alloy with yttrium and neodymium显示文摘The effects of rare earth(RE) elements Y and Nd on the microstructure and mechanical properties of Mg-6Al magnesium alloy were investigated.The results show that a proper level of RE elements can obviously ref ine the microstructure of Mg-6Al magnesium alloys,reduce the quantity of β-Mg17Al12 phase and form Al2Y and Al2Nd phases.The combined addition of Y and Nd dramatically enhances the tensile strength of the alloys in the temperature range of 20-175℃.When the content of RE elements is up to 1.8%,the values of tensile strength at room temperature and at 150℃ simultaneously reach their maximum of 253 MPa and 196 MPa,respectively.The main mechanisms of enhancement in the mechanical properties of Mg-6Al alloy with Y and Nd are the grain ref ining strengthening and the dispersion strengthening. | Chen Jun Li Quanan Li Jianghong Li Xiaofeng Li Kejie Zhang Xingyuan | 2009 | China Foundry2009，6，2： | 5 |
| 13 | Effects of sand-fixing and windbreak forests on wind flow:a synthesis of results from field experiments and numerical simulations显示文摘Sand-fixing and windbreak forests are widely used to protect or/and improve the ecological environments in arid and semi-arid regions. A full understanding of wind flow characteristics is essential to arranging the patterns of these protective forests for enhancing the effectiveness. In this study, the wind velocity over the underlying surface with sand-fixing forests and windbreak forests at the heights of 1–49 m was monitored from two 50-m high observation towers in an oasis of Minqin, Gansu Province of China. The wind velocities were simulated at different locations over these protective forests between those two towers by a two-dimensional Computational Fluid Dynamics(CFD) model. The results showed that at the heights of 1–49 m, the wind velocity profiles followed a classical logarithm law at the edge of the oasis and a multilayer structure inside the oasis. With increasing number of sand-fixing forest and windbreak forest arrays, the wind velocity at the heights of 1–49 m generally decreased along the downstream direction of the prevailing wind. Specifically, below the height of windbreak forests, the wind velocity decelerates as the airflow approaches to the windbreak forests and then accelerates as the airflow passes over the windbreak forests. In contrast, above the height of windbreak forests, the wind velocity accelerates as the airflow approaches to the windbreak forests and then generally decelerates as the airflow passes over the windbreak forests. Both the array number and array spacing of sand-fixing and windbreak forests could influence the wind velocity. The wind protection effects of sand-fixing forests were closely related to the array spacing of windbreak forests and increased with the addition of sand-fixing forests when the array of the forests was adequately spaced. However, if the array spacing of windbreak forests was smaller than seven times of the heights of windbreak forests, the effects were reduced or completely masked by the effects of windbreak forests. The results could offer theoretical guidelines on how to systematically arrange the patterns of sand-fixing and windbreak forests for preventing wind erosion in the most convenient and the cheapest ways. | ZHAN Kejie LIU Shizeng YANG Zihui FANG Etian ZHOU Lanping HUANG Ning | 2017 | Journal of Arid Land2017，9，1： | 4 |
| 14 | Adsorption Performance of Sliding Wall-Climbing Robot显示文摘Sliding wall-climbing robot(SWCR) is applied worldwide for its continuous motion,however,considerable air leakage causes two problems:great power consumption and big noise,and they constraint the robot's comprehensive performance.So far,effective theoretical model is still lacked to solve the problems.The concept of SWCR's adsorption performance is presented,and the techniques of improving utilization rate of given adsorption force and utilization rate of power are studied respectively to improve SWCR's adsorption performance.The effect of locomotion mechanism selection and seal's pressure allocation upon utilization rate of given adsorption force is discussed,and the theoretical way for relevant parameters optimization are provided.The directions for improving utilization rate of power are pointed out based on the detail analysis results of suction system's thermodynamics and hydrodynamics.On this condition,a design method for SWCR-specific impeller is presented,which shows how the impeller's key parameters impact its aerodynamic performance with the aid of computational fluid dynamics(CFD) simulations.The robot prototype,BIT Climber,is developed,and its functions such as mobility,adaptability on wall surface,payload,obstacle ability and wall surface inspection are tested.Through the experiments for the adhesion performance of the robot adsorption system on the normal wall surface,at the impeller's rated rotating speed,the total adsorption force can reach 237.2 N,the average effective negative pressure is 3.02 kPa and the design error is 3.8% only,which indicates a high efficiency.Furthermore,it is found that the robot suction system's static pressure efficiency reaches 84% and utilization rate of adsorption force 81% by the experiment.This thermodynamics model and SWCR-specific impeller design method can effectively improve SWCR's adsorption performance and expand this robot applicability on the various walls.A sliding wall-climbing robot with high adhesion efficiency is developed,and this robot has the features of light body in weight,small size in structure and good capability in payload. | LI Jun GAO Xueshan FAN Ningjun LI Kejie JIANG Zhihong JIANG Zhijian | 2010 | Chinese Journal of Mechanical Engineering2010，23，6： | 4 |
| 15 | Behavior of Pile Groups under Lateral Load显示文摘Based on investigation and model tests, and in combination with the research work on group effect for pile groups under lateral loads relating to the code of fixed offshore platforms, a series of studies have been performed on the behavior and failure mechanism of laterally loaded pile groups, critical pile spacing inducing group effect, lateral bearing capacity of pile groups and its main influence factors, the stress-strain relationship for single piles and pile groups and so on. Some new laws about non-uniformity of load distribution in the longitudinal direction of pile groups and load-deflection (p - y) curves for pile groups have been discovered, and an empirical formula is presented in order to remedy the defect of current calculating methods at home and abroad. These results can be used for reference in the design of pile foundation under lateral loads. | Yang, Keji Li, Qixin Wang, Fuyuan | 1991 | China Ocean Engineering1991，6，2： | 3 |
| 16 | Chinese Expert Consensus on Clinical Application of Oral Ginkgo biloba Preparations (2020)显示文摘Ginkgo(Ginkgo biloba L.)is aperennial deciduous tree of the Ginkgoaceae family,and its seeds(ginkgo nut)and leaves have high medicinal values.G.biloba was firstly recorded in Materia Medica in Shaoxin Medica;previous texts on Materia Medica have mostly listed ginkgo nuts. | Chinese Association of Integrative Medicine Chinese Medical Doctor Association National Clinical Research Center for Chinese Medicine Cardiology Cardiovascular Disease Working Group Encephalopathy Disease Working Group China Center for Evidence-Based Chinese Medicine CHEN Keji LIU Yue YANG Hua LIU Long-tao FU Chang-geng | 2021 | Chinese Journal of Integrative Medicine2021，27，3： | 3 |
| 17 | A phase 3,double-blind,randomized placebo-controlled efficacy and safety study of abiraterone acetate in chemotherapynaı¨ve patients with mCRPC in China,Malaysia,Thailand and Russia显示文摘Objective:This double-blind,placebo-controlled phase 3 study was designed to compare efficacy and safety of abiraterone acetate+prednisone(abiraterone)to prednisone alone in chemotherapy-naı¨ve,asymptomatic or mildly symptomatic metastatic castrationresistant prostate cancer(mCRPC)patients from China,Malaysia,Thailand and Russia.Methods:Adult chemotherapy-naı¨ve patients with confirmed prostate adenocarcinoma,Eastern Cooperative Oncology Group(ECOG)performance status(PS)grade 0e1,ongoing androgen deprivation(serum testosterone<50 ng/dL)with prostate specific antigen(PSA)or radiographic progression were randomized to receive abiraterone acetate(1000 mg,QD)t prednisone(5 mg,BID)or placebo t prednisone(5 mg,BID),until disease progression,unacceptable toxicity or consent withdrawal.Primary endpoint was improvements in time to PSA progression(TTPP).Results:Totally,313 patients were randomized(abiraterone:n Z 157;prednisone:n Z 156);and baseline characteristics were balanced.At clinical cut-off(median follow-up time:3.9 months),80% patients received treatment(abiraterone:n Z 138,prednisone:n Z 112).Median time to PSA progression was not reached with abiraterone versus 3.8 months for prednisone,attaining 58%reduction in PSA progression risk(HR=0.418;p<0.0001).Abirateronetreated patients had higher confirmed PSA response rate(50%vs.21%;relative odds=2.4;p<0.0001)and were 5 times more likely to achieve radiographic response than prednisonetreated patients(22.9%vs.4.8%,p=0.0369).Median survival was not reached.Most common(≥10% abiraterone vs.prednisone-treated)adverse events:bone pain(7%vs.14%),pain in extremity(6%vs.12%),arthralgia(10%vs.8%),back pain(7%vs.11%),and hypertension(15%vs.14%).Conclusion:Interim analysis confirmed favorable benefit-to-risk ratio of abiraterone in chemotherapy-naı¨ve men with mCRPC,consistent with global study,thus supporting use of abiraterone in this patient population. | Dingwei Ye Yiran Huang Fangjian Zhou Keji Xie Vsevolod Matveev Changling Li Boris Alexeev Ye Tian Mingxing Qiu Hanzhong Li Tie Zhou Peter De Porre Margaret Yu Vahid Naini Hongchuan Liang Zhuli Wu Yinghao Sun | 2017 | Asian Journal of Urology2017，4，2： | 3 |
| 18 | Investigation of gene expression profiles in coronary heart disease and functional analysis of target gene显示文摘The research outlined here includes constitution of the differential gene expression profile by means of oligonucleotide gene microarray and functional analysis of the target gene for coronary heart disease (CHD). In a microarray screening experiment, the predominance of inflammation- and immune-related genes is presented in the expression profile of 107 differential genes based on the analysis of gene ontology and gene pathway. IL-8, an inflammatory factor, is identified as one of the genes that were markedly up-regulated in CHD. The plasma level of IL-8 is significantly raised in patients with CHD (n = 30) compared with healthy controls (n = 40), which underscores the clinical relevance of the in vitro finding. The further functional analysis shows that IL-8 affects platelet aggregation percentage, ex-pression of CD62p and platelet aggregation morphology in 12 healthy volunteers to some extent. These findings suggest the relevance of inflammation and immune responses to CHD at the DNA level. Moreover, IL-8 may be involved in the pathogenesis of CHD through the pathway of platelet activation. | YIN HuiJun MA XiaoJuan JIANG YueRong SHI DaZhuo CHEN KeJi | 2009 | Chinese Science Bulletin2009，54，5： | 3 |
| 19 | MULTIAXIAL BEHAVIOR OF NANOPOROUS SINGLE CRYSTAL COPPER:A MOLECULAR DYNAMICS STUDY显示文摘The stress-strain behavior and incipient yield surface of nanoporous single crystal copper are studied by the molecular dynamics(MD) method.The problem is modeled by a periodic unit cell subject to multi-axial loading.The loading induced defect evolution is explored.The incipient yield surfaces are found to be tension-compression asymmetric.For a given void volume fraction,apparent size effects in the yield surface are predicted:the smaller behaves stronger.The evolution pattern of defects(i.e.,dislocation and stacking faults) is insensitive to the model size and void volume fraction.However,it is loading path dependent.Squared prismatic dislocation loops dominate the incipient yielding under hydrostatic tension while stacking-faults are the primary defects for hydrostatic compression and uniaxial tension/compression. | Kejie Zhao Liangliang Fan Changqing Chen | 2009 | Acta Mechanica Solida Sinica2009，22，6： | 2 |
| 20 | Lineage relationship of CD8^+ T cell subsets is revealed by progressive changes in the epigenetic landscape显示文摘 | Joseph G. Crompton Manikandan Narayanan Suresh Cuddapah Rahul Roychoudhuri Yun Ji Wenjing Yang Shashank J. Patel Madhusudhanan Sukumar Douglas C. Palmer Weiqun Peng Ena Wang Francesco M. Marincola Christopher A. Klebanoff Keji Zhao John S. Tsang Luca Gatt-inoni Nicholas P. Restifo | 2016 | Cellular & Molecular Immunology2016，13，4： | 2 |
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