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1175篇 您的检索式：作者名="Kelly O"

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	题名	作者	年代	出处	被引量
1	Metabolic reprogramming in macrophages and dendritic cells in innate immunity显示文摘	Beth Kelly Luke AJ O'Neill	2015	Cell Research2015，25，7：	70
2	Overview of recent advances in metastatic triple negative breast cancer显示文摘Metastatic triple negative breast cancer(TNBC)has an aggressive phenotype with a predilection for visceral organs and brain.Best responses to chemotherapy are predominately in the first line.Recent studies have demonstrated improved progression free survival with the combination of atezolizumab/pembrolizumab and chemotherapy in programmed death-ligand 1 positive metastatic TNBC.However,a recent trial in a similar population showed no benefit for atezolizumab and paclitaxel which led to a Food and Drug Administration alert.Two phase III trials(OLYMPIAD and BROCADE3)demonstrated a benefit in progression free survival(PFS)but not overall survival in patients with BRCAassociated metastatic TNBC treated with Olaparib or Talazoparib respectively.For those treated with Talazoparib,the time to deterioration in health related-quality of life was also longer compared to chemotherapy.The BROCADE3 trial demonstrated that the combination of a platinum and veliparib increased PFS in first-line metastatic TNBC but at the cost of increased toxicity.There are no headto-head comparisons of a poly(adenosine diphosphate-ribose)polymerase inhibitors(PARPi)and platinums.There are unanswered questions regarding the role of PARPi maintenance after platinum therapy as is standard of care in BRCAassociated ovarian cancer.Other areas of therapeutic interest include targeting aberrations in the phosphoinositide 3-kinase pathway,protein kinase B,mammalian target of rapamycin or utilising antibody drug conjugates.This review focusses on recent and emerging therapeutic options in metastatic TNBC.We searched PubMed,clinicaltrials.gov and recent international meetings from American Society of Clinical Oncology,San Antonio Breast Cancer Conference and the European Society of Medical Oncology.	David O'Reilly Maha Al Sendi Catherine M Kelly	2021	World Journal of Clinical Oncology2021，12，3：	5
3	Lactobacillus and bifidobacterium in irritable bowel syndrome: Symptom responses and relationship to cytokine profiles显示文摘	Liam O’Mahony Jane McCarthy Peter Kelly George Hurley Fangyi Luo Kersang Chen Gerald C. O’Sullivan Barry Kiely J. Kevin Collins Fergus Shanahan Eamonn M.M. Quigley	2005	Gastroenterology2005，，3：	2
4	An introduction to wavelet analysis in oceanography and meteorology: with application to the dispersion of Yannai waves显示文摘	Meyers S D Kelly B G O'Brien J J	1993	Mon Wea Rev1993，121，10：	2
5	Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA , IDH1 , EGFR , and NF1显示文摘	Roel G.W. Verhaak Katherine A. Hoadley Elizabeth Purdom Victoria Wang Yuan Qi Matthew D. Wilkerson C. Ryan Miller Li Ding Todd Golub Jill P. Mesirov Gabriele Alexe Michael Lawrence Michael O'Kelly Pablo Tamayo Barbara A. Weir Stacey Gabriel Wendy Winckler	2010	Cancer Cell2010，，1：	2
6	Correlation between bovine milksomatic cell count and polymorphonuclear leukocyte level for samples of bulkmilk and milk from individual cows显示文摘	Kelly A L Tiernan D O'Sullivan C	2000	Journal of Dairy Science2000，83，2：	1
7	Preoperative chemotherapy for colorectal liver metasases:impact on hepatic histology and postoperative outcome显示文摘	Timothy MP Kelly O Ana LG	2007	Gastrointest Surg2007，11，7：	1
8	A geographer's analysis of hub - and - spoke networks显示文摘	Morton E O' Kelly	1998	Journal of Transport Geography1998，6，3：	1
9	A geographer's analysis of hub-and-spoke networks显示文摘	Morton E O'Kelly	1998	Journal of Transport Geography1998，6，3：	1
10	Influence of transglutaminase treatment on properties of micellar casein and products made therefrom 显示文摘	Mounsey J S O ' Kennedy B T Kelly P M	2005	Lait2005，85，：	1
11	An information theoretic approach to measurement of spatial inequality显示文摘	Wash J A O’Kelly M E	1979	Econ Soc Rev1979，，10：	1
12	Using points of presence to measure ac- cessibility to the commercial internet显示文摘	Grubesic T H O'Kelly M E	2002	The Professional Geogra- pher2002，54，2：	1
13	Hub networks and simulated schedule delay显示文摘	Grove P G O'Kelly M E	1986	Papers in Regional Science1986，59，1：	1
14	Effect of Damping on the Natural Frequencies of Linear Dynamic Systems 显示文摘	Caughey T K O'Kelly E J M	1961	Journal of The Acoustical society of America1961，33，11：	1
15	Potassium leak channels and the KCNK family of two-P- domain subunits显示文摘	Goldstein SA Bockenhauer D O'Kelly I	2001	Nat Rev Neurosci2001，2，3：	1
16	Cytoskeletal changes regulated by the PAK4 serine/threonine kinase are mediated by LIM kinase 1 and cofilin显示文摘	Dan C Kelly A Bernard O Minden A	2001	J Biol Chem2001，276，32：	1
17	Haemorrhage control in pelvic fractures—A survey of surgical capabilities显示文摘	A.J. Metcalfe K. Davies B. Ramesh A. O’Kelly R. Rajagopal	2010	Injury2010，，10：	1
18	Complications of elbow arthroscopy显示文摘	Kelly EW Morrey BF O' driscoll SW	2001	J Bone Joint Surg Am2001，83，1：	1
19	Enhanced efficiency in the production of offspring from 4- to 8-week-old lambs 显示文摘	KELLY J M KLEEMANN D O WALKER S K	2005	Theriogenology2005，63，：	1
20	Cyv61 suppresses the growth of non-small-cell lung cancer cells via the beta-catenin-c-myc-p53 pathway 显示文摘	Tong X O' Kelly J Xie D	2004	Oncogene2004，23，28：	1

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