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| 1 | Vanishing bile duct syndrome in human immunodeficiency virus infected adults:A report of two cases显示文摘Vanishing bile duct syndrome(VBDS) is a group of rare disorders characterized by ductopenia,the progressive destruction and disappearance of intrahepatic bile ducts leading to cholestasis.Described in association with medications,autoimmune disorders,cancer,transplantation,and infections,the specific mechanisms of disease are not known.To date,only 4 cases of VBDS have been reported in human immunodeficiency virus(HIV) infected patients.We report 2 additional cases of HIV-associated VBDS and review the features common to the HIV-associated cases.Presentation includes hyperbilirubinemia,normal liver imaging,and negative viral and autoimmune hepatitis studies.In HIV-infected subjects,VBDS occurred at a range of CD4+ T-cell counts,in some cases following initiation or change in antiretroviral therapy.Lymphoma was associated with two cases;nevirapine,antibiotics,and viral co-infection were suggested as etiologies in the other cases.In HIV-positive patients with progressive cholestasis,early identification of VBDS and referral for transplantation may improve outcomes. | Ana Paula Oppenheimer Christopher Koh Mary McLaughlin John C Williamson Thomas D Norton Jennifer Laudadio Theo Heller David E Kleiner Kevin P High Caryn G Morse | 2013 | World Journal of Gastroenterology2013，19，1： | 8 |
| 2 | Is there an anatomical endophenotype for neurodevelopmental disorders? A review of dual disorder anatomical likelihood estimation (ALE) meta-analyses of grey matter volumes显示文摘The term 'neurodevelopmental disorder' broadly encompasses conditions thought to arise early in development and includes schizophrenia, bipolar disorder and autism among others. These conditions share a number of genetic and environmental risk factors postulated to lead to common difficulties in socio-emotional processing, communication and cognitive function. The alternative position is that, while the same traits are affected across these conditions, the nature or direction in which they are modified may be distinct. MRI studies provide a rapidly expanding and rich database which we propose can be used to contribute to this debate. Anatomical likelihood estimation (ALE) is a method of meta-analysis applied to voxel-based MRI studies. We have adapted this method to explore the extent to which schizophrenia and bipolar disorder and schizophrenia and autism share a common brain structural phenotype. We will review this work here and discuss whether there is sufficient other evidence to justify a common framework for further research into the inter-relatedness of such conditions. | MCALONAN Grainne M YU Kevin K CHAN Raymond C K CHUA Siew E CHEUNG Charlton | 2011 | Chinese Science Bulletin2011，56，32： | 2 |
| 3 | 查看详情显示文摘 | Florencio E H Kevin D B Ion C | | 0，，： | 1 |
| 4 | Transgenic pigs as bioreactors: a comparison ofgamma-carboxylation of glutamic acid in recombinant humanprotein C and factor Ⅸ by the mammary gland显示文摘 | KEVIN E V C STEPHEN P B CHRISTOPHER G R | 1999 | Genetic Analysis: Biomolecular Engineering1999，15，： | 1 |
| 5 | Dynamic interfacial tension of crude oil/alkali/surfactant systems显示文摘 | HISHAM A NASR E D KEVIN C T | 1992 | Colloids and Surfaces1992，66，： | 1 |
| 6 | Effects of NOx, a-Fe203, y-Fe203, and HC1 on mercury transformations in a 7-kW coal combustion system 显示文摘 | Kevin C G Christopher J Z James E T | 2004 | Fuel Processing Technology2004，434，86： | 1 |
| 7 | Efficacy of pazopanib in progressive, radioiodine-refractory, metastatic differentiated thyroid cancers: results of a phase 2 consortium study显示文摘 | Keith C Bible Vera J Suman Julian R Molina Robert C Smallridge William J Maples Michael E Menefee Joseph Rubin Kostandinos Sideras John C Morris Bryan McIver Jill K Burton Kevin P Webster Carolyn Bieber Anne M Traynor Patrick J Flynn Boon Cher Goh Hui Tan | 2010 | Lancet Oncology2010，，10： | 1 |
| 8 | Left ventricular lead proximity to an akinetic segment and impact on outcome of cardiac resynchronization therapy显示文摘 | Arzola-Castaner D Taub C Kevin Heist E | 2006 | J Cardiovasc Electrophysiol2006，17，6： | 1 |
| 9 | Transoral Incisionless Fundoplication: 2-year Results from the Prospective Multicenter U.S. Study显示文摘 | Bell Reginald C W Barnes William E Carter Bart J Sewell Robert W Mavrelis Peter G Ihde Glenn M Hoddinott Kevin M Fox Mark A Freeman Katherine D Gunsberger Tanja Hausmann Mark G Dargis David Gill Brian DaCosta Wilson Erik Trad Karim S | 2014 | The American Surgeon2014，，11： | 1 |
| 10 | Influence of the extraction methodology on the analysis of polycyclic aromatic hydrocarbons in pasture vegetation 显示文摘 | Kilian S E C Grant N L Kevin J C | 2006 | Journal of Chromatography A2006，1116，1： | 1 |
| 11 | Studies toward the large scale synthesis of the HIV proteinase inhibitor Ro 31-8959显示文摘 | Kevin E B P David J B Peter H C | 1994 | J Org Chem1994，59，13： | 1 |
| 12 | Monahan managing inventories in a two-echelon dual-channel supply chain显示文摘 | Wei-yu Kevin C George E | 2005 | European Journal of Operational Research2005，162，： | 1 |
| 13 | Managing inventories in a two-echelon dual-channel supply chain显示文摘 | Kevin C W Monahan G E | | 0，，02： | 1 |
| 14 | Mitochondrial DNA mutations in individuals occupationally exposed to ionizing radiation显示文摘 | Craig S W Kevin C E Janet T C | 2006 | Radiat Res2006，165，2： | 1 |
| 15 | IPO Pricing and Share Allocation:The Importance of Being Ignorant显示文摘 | C(E)LINE GONDAT-LARRALDE KEVIN R.JAMES | | 0，，02： | 1 |
| 16 | Novel approach to synthesis of FePt magnetic nanoparticles 显示文摘 | Kevin E E Girija S C Vikas N | 2008 | j Nano Res2008，，1： | 1 |
| 17 | Managing inventories in a two-echelon dual-channel supply chain显示文摘 | Kevin W Y Monahan C G E | 2005 | European Journal of Operational Research2005，162，： | 1 |
| 18 | The spatial configuration of travel to Yellowstone National Park 显示文摘 | ROBERT C MINGS KEVIN E MCHUGH | 1992 | Journal of Travel Research1992，，： | 1 |
| 19 | Managing Inventories in a Two-echelon Dual Channel Supply Chain显示文摘 | Wei Y Kevin C Monahan G E | 2005 | European Journal of Operational Research2005，162，： | 1 |
| 20 | BAK1, an Arabidopsis LRR Receptor-like Protein Kinase, Interacts with BRI1 and Modulates Brassinosteroid Signaling显示文摘 | Jia Li Jiangqi Wen Kevin A Lease Jason T Doke Frans E Tax John C Walker | 2002 | Cell2002，，2： | 1 |
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