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| 1 | Non-robotic minimally invasive gastrectomy as an independent risk factor for postoperative intra-abdominal infectious complications: A single-center, retrospective and propensity score-matched analysis显示文摘BACKGROUND Minimally invasive surgery for gastric cancer(GC) has gained widespread use as a safe curative procedure especially for early GC.AIM To determine risk factors for postoperative complications after minimally invasive gastrectomy for GC.METHODS Between January 2009 and June 2019, 1716 consecutive patients were referred to our division for primary GC. Among them, 1401 patients who were diagnosed with both clinical and pathological Stage Ⅲ or lower GC and underwent robotic gastrectomy(RG) or laparoscopic gastrectomy(LG) were enrolled. Retrospective chart review and multivariate analysis were performed for identifying risk factors for postoperative morbidity.RESULTS Morbidity following minimally invasive gastrectomy was observed in 7.5% of the patients. Multivariate analyses demonstrated that non-robotic minimally invasive surgery, male gender, and an operative time of ≥ 360 min were significant independent risk factors for morbidity. Therefore, morbidity was compared between RG and LG. Accordingly, propensity-matched cohort analysis revealed that the RG group had significantly fewer intra-abdominal infectious complications than the LG group(2.5% vs 5.9%, respectively;P = 0.038), while no significant differences were noted for other local or systemic complications.Multivariate analyses of the propensity-matched cohort revealed that non-robotic minimally invasive surgery [odds ratio = 2.463(1.070–5.682);P = 0.034] was a significant independent risk factor for intra-abdominal infectious complications.CONCLUSION The findings showed that robotic surgery might improve short-term outcomes following minimally invasive radical gastrectomy by reducing intra-abdominal infectious complications. | Susumu Shibasaki Koichi Suda Masaya Nakauchi Kenichi Nakamura Kenji Kikuchi Kazuki Inaba Ichiro Uyama | 2020 | World Journal of Gastroenterology2020,26,11: | 8 |
| 2 | Repeat endoscopic submucosal dissection for recurrent gastric cancers after endoscopic submucosal dissection显示文摘AIM:To clarify the safety and efficacy of repeat endoscopic submucosal dissection(re-ESD)for locally recurrent gastric cancers after ESD.METHODS:A retrospective evaluation was performed of the therapeutic efficacy,complications and followup results from ESD treatment for early gastric cancers in 521 consecutive patients with 616 lesions at St.Luke`s International Hospital between April 2004 and November 2012.In addition,tumor size,the size of resected specimens and the operation time were compared between re-ESD and initial ESD procedures.A flex knife was used as the primary surgical device and a hook knife was used in cases with severe fibrosis in the submucosal layer.Continuous variables were analyzed using the non-parametric Mann-Whitney U test and are expressed as medians(range).Categorical variables were analyzed using a Fisher’s exact test and are reported as proportions.Statistical significance was defined as a P-value less than 0.05.RESULTS:The number of cases in the re-ESD group and the initial ESD group were 5 and 611,respectively.The median time interval from the initial ESD to re-ESD was 14(range,4-44 mo).En bloc resection with free lateral and vertical margins was successfully performed in all re-ESD cases without any complications.No local or distant recurrence was observed during the median follow-up period of 48(range,11-56 mo).Tumor size was not significantly different between the re-ESD group and the initial ESD group(median 22 mm vs 11mm,P=0.09),although the size of resected specimens was significantly larger in the re-ESD group(median 47 mm vs 34 mm,P<0.05).There was a nonsignificant increase observed in re-ESD operation time compared to initial ESD(median 202 min vs 67 min,respectively,P=0.06).CONCLUSION:Despite the low patient number and short follow-up,the results suggest that re-ESD is a safe and effective endoscopic treatment for recurrent gastric cancer after ESD. | Yuto Shimamura Naoki Ishii Kaoru Nakano Takashi Ikeya Kenji Nakamura Koichi Takagi Katsuyuki Fukuda Koyu Suzuki Yoshiyuki Fujita | 2013 | World Journal of Gastrointestinal Endoscopy2013,5,12: | 5 |
| 3 | High-speed unsteady flows past two-body configurations显示文摘This paper presents a detailed investigation of unsteady supersonic flows around a typical two-body configuration, which consists of a capsule and a canopy.The cases with different trailing distances between the capsule and canopy are simulated.The objective of this study is to examine the detailed effects of trailing distance on the flow fields and analyze the flow physics of the different flow modes around the parachute-like two-body model.The computational results show unsteady pulsating flow fields in the small trailing distance cases and are in reasonable agreement with the experimental data.As the trailing distance increases, this unsteady flow mode takes different forms along with the wake/shock and shock/shock interactions, and then gradually fades away and transits to oscillate mode, which is very different from the former.As the trailing distance keeps increasing, only the capsule wake/canopy shock interaction is present in the flow field around the two-body model, which reveals that the unsteady capsule shock/canopy shock interaction is a key mechanism for the pulsation mode. | Xiaopeng XUE Yusuke NISHIYAMA Yoshiaki NAKAMURA Koichi MORI Yunpeng WANG ChihYung WEN | 2018 | Chinese Journal of Aeronautics2018,31,1: | 3 |
| 4 | Endoscopic removal of foreign bodies:A retrospective study in Japan显示文摘BACKGROUND The ingestion of foreign bodies(FBs)and food bolus impaction(FBI)in the digestive tract are commonly encountered clinical problems.Methods to handle such problems continue to evolve offering advantages,such as the avoidance of surgery,reduced cost,improved visualization,reduced morbidity,and high removal success rate.However,to date,no studies have evaluated the endoscopic management of FBs in Japan.AIM To elucidate level of safety and efficacy in the endoscopic management of FBs and FBI.METHODS A total of 215 procedures were performed at Keio University Hospital between November 2007 and August 2018.Data were collected from medical charts,and endoscopic details were collected from an endoscopic reporting system.Procedures performed with a flexible gastrointestinal endoscope were only taken into account.Patients who underwent a technique involving FB or FBI from the digestive tract were only included.Data on patient sex,patient age,outpatient,inpatient,FB type,FB location,procedure time,procedure type,removal device type,success,and technical complications were reviewed and analyzed retrospectively.RESULTS Among the 215 procedures,136(63.3%)were performed in old adults(≥60 years),180(83.7%)procedures were performed in outpatients.The most common type of FBs were press-through-pack(PTP)medications[72(33.5%)cases],FBI[47(21.9%)],Anisakis parasite(AP)[41(19.1%)cases].Most FBs were located in the esophagus[130(60.5%)cases]followed by the stomach[68(31.6%)cases].AP was commonly found in the stomach[39(57.4%)cases],and it was removed using biopsy forceps in 97.5%of the cases.The most common FBs according to anatomical location were PTP medications(40%)and dental prostheses(DP)(40%)in the laryngopharynx,PTP(48.5%)in the esophagus,AP(57.4%)in the stomach,DP(37.5%)in the small intestine and video capsule endoscopy device(75%)in the colon.A transparent cap with grasping forceps was the most commonly used device[82(38.1%)cases].The success rate of the procedure was 100%,and complication were observed in only one case(0.5%).CONCLUSION Endoscopic management of FBs and FBI in our Hospital is extremely safe and effective. | Kenji JL Limpias Kamiya Naoki Hosoe Kaoru Takabayashi Yukie Hayashi Xi Sun Ryoichi Miyanaga Kayoko Fukuhara Seiichiro Fukuhara Makoto Naganuma Atsushi Nakayama Motohiko Kato Tadateru Maehata Rieko Nakamura Koichi Ueno Junichi Sasaki Yuko Kitagawa Naohisa Yahagi Haruhiko Ogata Takanori Kanai | 2020 | World Journal of Gastrointestinal Endoscopy2020,12,1: | 3 |
| 5 | Neoadjuvant chemotherapy with gemcitabine for pancreatic cancer increasesin situ expression of the apoptosis marker M30 and stem cell marker CD44显示文摘 | Hidehiro Tajima Tetsuo Ohta Hirohisa Kitagawa Koichi Okamoto Seisho Sakai Jun Kinoshita Isamu Makino Hiroyuki Furukawa Hironori Hayashi Keishi Nakamura Katsunobu Oyama Masafumi Inokuchi Hisatoshi Nakagawara Hideto Fujita Hiroyuki Takamura Itasu Ninomiya S | 2012 | Oncology Letters2012,,: | 2 |
| 6 | The preoperative plasma D-dimer level is an independent prognostic factor in patients with completely resected non-small cell lung cancer显示文摘 | Koichi Fukumoto Tetsuo Taniguchi Noriyasu Usami Koji Kawaguchi Takayuki Fukui Futoshi Ishiguro Shota Nakamura Kohei Yokoi | 2015 | Surgery Today2015,,1: | 2 |
| 7 | Anatomical variations and surgical strategies in right lobe living donor liver transplantation: lessons from 120 cases1显示文摘 | Taro Nakamura Koichi Tanaka Tetsuya Kiuchi Mureo Kasahara Fumitaka Oike Mikiko Ueda Satoshi Kaihara Hiroto Egawa Ilgin Ozden Nobuaki Kobayashi Shinji Uemoto | 2002 | Transplantation2002,,12: | 1 |
| 8 | Prognostic factors of minimally invasive surgery for gastric cancer: Does robotic gastrectomy bring oncological benefit?显示文摘BACKGROUND Gastric cancer is the third leading cause of cancer-related death worldwide and surgical resection remains the sole curative treatment for gastric cancer.Minimally invasive gastrectomy including laparoscopic and robotic approaches has been increasingly used in a few decades.Thus far,only a few reports have investigated the oncological outcomes following minimally invasive gastrectomy.AIM To determine the 5-year survival following minimally invasive gastrectomy for gastric cancer and identify prognostic predictors.METHODS This retrospective cohort study identified 939 patients who underwent gastrectomy for gastric cancer during the study period.After excluding 125 patients with non-curative surgery(n=77),other synchronous cancer(n=2),remnant gastric cancer(n=25),insufficient physical function(n=13),and open gastrectomy(n=8),a total of 814 consecutive patients with primary gastric cancer who underwent minimally invasive R0 gastrectomy at our institution between 2009 and 2014 were retrospectively examined.Accordingly,5-year overall and recurrence-free survival were analyzed using the Kaplan–Meier method with the log-rank test and Cox regression analyses,while factors associated with survival were determined using multivariate analysis.RESULTS Our analysis showed that age>65 years,American Society of Anesthesiologists(ASA)physical status 3,total or proximal gastrectomy,and pathological T4 and N positive status were independent predictors of both 5-year overall and recurrencefree survival.Accordingly,the included patients had a 5-year overall and recurrence-free survival of 80.3%and 78.2%,respectively.Among the 814 patients,157(19.3%)underwent robotic gastrectomy,while 308(37.2%)were diagnosed with pathological stage II or III disease.Notably,our findings showed that robotic gastrectomy was an independent positive predictor for recurrence-free survival in patients with pathological stage II/III[hazard ratio:0.56(0.33-0.96),P=0.035].Comparison of recurrence-free survival between the robotic and laparoscopic approach using propensity score matching analysis verified that the robotic group had less morbidity(P=0.005).CONCLUSION Age,ASA status,gastrectomy type,and pathological T and N status were prognostic factors of minimally invasive gastrectomy,with the robot approach possibly improving long-term outcomes of advanced gastric cancer. | Masaya Nakauchi Koichi Suda Susumu Shibasaki Kenichi Nakamura Shinichi Kadoya Kenji Kikuchi Kazuki Inaba Ichiro Uyama | 2021 | World Journal of Gastroenterology2021,27,39: | 1 |
| 9 | Magnetic properties of extremely small Nd-Fe-B sintered mag- nets显示文摘 | Hajime Nakamura Koichi Hirota Masanobu Shimao | 2005 | IEEE Transactions on Magnetics2005,41,10: | 1 |
| 10 | Mechanical stretch augments PDGF receptor β expression and protein tyrosine phosphorylation in pulmonary artery tissue and smooth muscle cells显示文摘 | Yoshiyuki Tanabe Maki Saito Akiko Ueno Mariko Nakamura Keiichi Takeishi Koichi Nakayama | 2000 | Molecular and Cellular Biochemistry (-)2000,,1: | 1 |
| 11 | Photodecomposition of kraft lignin catalyzed by titanium dioxide显示文摘 | Kobayakawa Koichi Sato Yuichi Nakamura Shigeo | 1989 | Bull Chem Soc Jpn1989,62,11: | 1 |
| 12 | Photodecomposition of kraft lignin catalyzed by titanium dioxide显示文摘 | Kobayakawa Koichi Sato Yuichi Nakamura Shigco | 1989 | Bull Chcm Soc Jpn1989,62,11: | 1 |
| 13 | Current concepts of carpal tunnel syndrome: pathophysiology, treatment, and evaluation显示文摘 | Shigeharu Uchiyama Toshirou Itsubo Koichi Nakamura Hiroyuki Kato Takashi Yasutomi Toshimitsu Momose | 2010 | Journal of Orthopaedic Science2010,,1: | 1 |
| 14 | Nationwide Survey of Hemophagocytic Lymphohistiocytosis in Japan显示文摘 | Eiichi Ishii Shouichi Ohga Shinsaku Imashuku Masaki Yasukawa Hiroyuki Tsuda Ikuo Miura Ken Yamamoto Hisanori Horiuchi Kenzo Takada Koichi Ohshima Shigeo Nakamura Naoko Kinukawa Kazuo Oshimi Keisei Kawa | 2007 | International Journal of Hematology2007,,1: | 1 |
| 15 | Development of an ultra-high resolution SPECT system with a CdTe semiconductor detector显示文摘 | Koichi Ogawa Naoka Ohmura Hirokazu Iida Kayoko Nakamura Tadaki Nakahara Atsushi Kubo | 2009 | Annals of Nuclear Medicine2009,,8: | 1 |
| 16 | Gastric undifferentiated carcinoma with diffuse c-kit overexpression and focal neuroendocrine differentiation显示文摘 | Daisuke Mori Michiaki Akashi Koichi Baba Kiyoto Morito Masami Shibaki Michinori Hashimoto Akashi Nakamura Seiko Mawatari Seiji Sato | 2013 | Pathology - Research and Practice2013,,2: | 1 |
| 17 | Adult pancreatic hemangioma: A case report显示文摘 | Yoshiki Naito Naoyo Nishida Yasuhiro Nakamura Yoshikuni Torii Hiroshi Yoshikai Hiroshi Kawano Tetsuji Akiyama Terufumi Sakai Satoru Taniwaki Masaya Tanaka Hisashi Kuroda Koichi Higaki | 2014 | Oncology Letters2014,,2: | 1 |
| 18 | PMU based midterm stability evaluation of wide-area power system显示文摘 | Yutaka Ota Hiroyuki Koichi Nakamura | 2002 | IEEE Transactions on Power Systems2002,17,2: | 1 |
| 19 | TARC and RANTES enhance antitumor immunity induced by the GM-CSF-transduced tumor vaccine in a mouse tumor model显示文摘 | Hiroyuki Inoue Mutsunori Iga Meng Xin Saori Asahi Takafumi Nakamura Ryo Kurita Masaharu Nakayama Yukoh Nakazaki Koichi Takayama Yoichi Nakanishi Kenzaburo Tani | 2008 | Cancer Immunology Immunotherapy2008,,9: | 1 |
| 20 | Angiotensin-converting enzyme inhibition reduces monocyte chemoattractant protein-1 and tissue factor levels in patients with myocardial infarction显示文摘 | Hirofumi Soejima Hisao Ogawa Hirofumi Yasue Koichi Kaikita Keiji Takazoe Koichi Nishiyama Kenji Misumi Shinzo Miyamoto Michihiro Yoshimura Kiyotaka Kugiyama Shin Nakamura Ichiro Tsuji | 1999 | Journal of the American College of Cardiology1999,,4: | 1 |