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| 1 | Sporadic fundic gland polyps are not associated with proton pump inhibitors therapy but negatively correlate with Helicobacter pylori infection in China显示文摘 | Cao Hailong Qu Rui Zhang Zhihua Kong Xinyue Wang Shan Jiang Kui Wang Bangmao | 2014 | Chinese Medical Journal2014，，7： | 29 |
| 2 | Cold adaptation in pigs depends on UCP3 in beige adipocytes显示文摘 | Jun Lin Chunwei Cao Cong Tao Rongcai Ye Meng Dong Qiantao Zheng Chao Wang Xiaoxiao Jiang Guosong Qin Changguo Yan Kui Li John R. Speakman Yanfang Wang Wanzhu Jin Jianguo Zhao | 2017 | Journal of Molecular Cell Biology2017，9，5： | 20 |
| 3 | The Genome of Medicinal Plant Macleaya cordata Provides New Insights into Benzylisoquinoline Alkaloids Metabolism显示文摘在动物农业和药的抗菌素的 overuse 引起了一系列潜在的威胁到公共健康。Macleaya cordata 是从 Papaveraceae 家庭的药用的植物种,提供为抗菌剂的制造的一个安全资源为家畜喂添加剂。从 M. 的活跃成分 ? cordata 被知道包括 benzylisoquinoline 碱(偏爱) 象 sanguinarine (圣) 和 chelerythrine (CHE ) 那样的 ?,而是他们的新陈代谢的小径还得在这非模型植物被学习。在 M. 的圣和 CHE 的活跃生合成 ? cordata 被喂 13标记 C 的酷氨酸。为了增加,推进卓见,我们 de novo 定序 M 的整个染色体。cordata,第一从 Papaveraceae 家庭被定序。M.? 盖住 378 Mb 的 cordata 染色体与 43.5%being 编码 22,328 预言的编码蛋白质的基因 transposable 元素。作为基础 eudicot 的一个成员, M.? cordata 染色体缺乏 ? 发生在几乎所有 eudicots 的 paleohexaploidy 事件。从 genomics 数据, 16 的一个完全的集合 ? 新陈代谢 ? 为圣和 CHE 生合成的基因被检索,并且 14 项他们的生物化学的活动被验证。这些 genomics 和新陈代谢的数据在 M. 显示出保存 BIA 新陈代谢的小径 ? cordata 并且由庄稼改进或微生物引起的小径重建为圣和 CHE 的未来生产提供知识基础。 | Xiubin Liu Yisong Liu Peng Huang Yongshuo Ma Zhixing Qing Qi Tang Huifen Cao Pi Cheng Yajie Zheng Zejun Yuan Yuan Zhou Jinfeng Liu Zhaoshan Tang Yixiu Zhuo Yancong Zhang Linlan Yu Jialu Huang Peng Yang Qiong Peng dinbo Zhang Wenkai Jiang Zhonghua Zhang Kui Lin Dae-Kyun Ro Xiaoya Chen Xingyao Xiong Yi Shang Sanwen Huang Jianguo Zeng | 2017 | Molecular Plant2017，10，7： | 19 |
| 4 | Synthesis and antitumor and antibacterial evaluation of fluoroquinolone derivatives(Ⅲ):Mono- and bis-Schiff-bases显示文摘To further explore an efficient modified route for the shift from an antibacterial fluoroquinolone to an antitumor one,mono-Schiff bases 6a-6h related to ciprofloxacin C3 carbonylhydrazone and bis-Schiff bases 4a-4h corresponding to C3/C7 carbonylhydrazone/hydrazone attached on a skeleton of ciprofloquinolone were designed and synthesized,and their in vitro antitumor activity against CHO,HL60,L1210 cells and antibacterial activity against Staphylococcus aureus and Escherichia coli were also reported. | Guo Qiang Hu Xiao Kui Wu Guo Qiang Wang Nan Nan Duan Xiao Yi Wen Tie Yao Cao Yin Jun Wang Wei Song Qiang Xie Wen Long Huang | 2012 | Chinese Chemical Letters2012，23，5： | 8 |
| 5 | Effect of Lactobacillus rhamnosus GG supernatant on serotonin transporter expression in rats with post-infectious irritable bowel syndrome显示文摘AIM To evaluate the effect of Lactobacillus rhamnosus GG supernatant(LGG-s) on the expression of serotonin transporter(SERT) in rats with post-infectious irritable bowel syndrome(PI-IBS).METHODS Campylobacter jejuni 81-176(1010 CFU/m L) was used to induce intestinal infection to develop a PI-IBS model. After evaluation of the post-infectious phase by biochemical tests, Dn A agarose gel electrophoresis, abdominal withdrawal reflex(AWR) test, and the intestinal motility test, four PI-IBS groups received different concentrations of LGG-s for 4 wk. The treatments were maintained for 1.0, 2.0, 3.0 or 4.0 wk during the experiment, and the colons and brains were removed for later use each week. SERT m Rn A and protein levels were detected by real-time PCR and Western blot, respectively.RESULTS The levels of SERT m Rn A and protein in intestinal tissue were higher in rats treated with LGG-s than in control rats and PI-IBS rats gavaged with PBS during the whole study. Undiluted LGG-s up-regulated SERT m Rn A level by 2.67 times compared with the control group by week 2, and SERT m Rn A expression kept increasing later. Double-diluted LGG-s was similar to undiluted-LGG-s, resulting in high levels of SERT m Rn A. Triple-diluted LGG-s up-regulated SERT m Rn A expression level by 6.9-times compared with the control group, but SERT m Rn A expression decreased rapidly at the end of the second week. At the first week, SERT protein levels were basically comparable in rats treated with undiluted LGG-s, double-diluted LGG-s, and triplediluted LGG-s, which were higher than those in the control group and PBS-treated PI-IBS group. SERT protein levels in the intestine were also comparable in rats treated with undiluted LGG-s, double-diluted LGG-s, and triple-diluted LGG-s by the second and third weeks. SERT m Rn A and protein levels in the brain had no statistical difference in the groups during the experiment.CONCLUSION LGG-s can up-regulate SERT m Rn A and protein levels in intestinal tissue but has no influence in brain tissue in rats with PI-IBS. | Ya-nan Cao Li-juan Feng Yuan-Yuan Liu Kui jiang Mao-jun Zhang Yi-xin Gu Bang-Mao Wang jia Gao Ze-Lan Wang Yu-Ming Wang | 2018 | World Journal of Gastroenterology2018，24，3： | 7 |
| 6 | Nitrogen and Phosphorus Dual-Doped Multilayer Graphene as Universal Anode for Full Carbon-Based Lithium and Potassium Ion Capacitors显示文摘Lithium/potassium ion capacitors(LICs/PICs) have been proposed to bridge the performance gap between high-energy batteries and high-power capacitors.However,their development is hindered by the choice,electrochemical performance,and preparation technique of the battery-type anode materials.Herein,a nitrogen and phosphorus dual-doped multilayer graphene(NPG) material is designed and synthesized through an arc discharge process,using low-cost graphite and solid nitrogen and phosphorus sources.When employed as the anode material,NPG exhibits high capacity,remarkable rate capability,and stable cycling performance in both lithium and potassium ion batteries.This excellent electrochemical performance is ascribed to the synergistic effect of nitrogen and phosphorus doping,which enhances the electrochemical conductivity,provides a higher number of ion storage sites,and leads to increased interlayer spacing.Full carbon-based NPG‖LiPF6‖active carbon(AC) LICs and NPG‖KPF6‖AC PICs are assembled and show excellent electrochemical performance,with competitive energy and power densities.This work provides a route for the large-scale production of dual-doped graphene as a universal anode material for high-performance alkali ion batteries and capacitors. | Yuting Luan Rong Hu Yongzheng Fang Kai Zhu Kui Cheng Jun Yan Ke Ye Guiling Wang Dianxue Cao | 2019 | Nano-Micro Letters2019，11，2： | 6 |
| 7 | Electrostatic self-assembly of MXene and edge-rich CoAl layered double hydroxide on molecular-scale with superhigh volumetric performances显示文摘It is highly desirable to design and synthesize two-dimensional nanostructured electrode materials with high electrical conductivity,large electrolyte-accessible surface area and more exposed active sites for energy storage applications.Herein,MXene/Co Al-LDH heterostructure has been prepared through electrostatic ordered hetero-assembly of monolayer MXene and edge-rich Co Al-LDH nanosheets in a faceto-face manner on molecular-scale for supercapacitor applications.Benefiting from the unique structure,strong interfacial interaction and synergistic effects between MXene and Co Al-LDH nanosheets,the electrical conductivity and exposed electrolyte-accessible active sites are significantly enhanced.The asprepared MXene/Co Al-LDH-80%(ML-80)film exhibits high volumetric capacity of 2472 C cm-3 in 3 M KOH electrolyte with high rate capability of 70.6%at 20 A g-1.Notably,to the best of our knowledge,the high volumetric capacity is the highest among other previously reported values for supercapacitors in aqueous electrolytes.Furthermore,our asymmetric supercapacitor device fabricated with ML-80 and MXene/graphene composite as cathode and anode,respectively,exhibits impressive volumetric energy density of 85.4 Wh L-1 with impressive cycling stability of 94.4%retention ratio after 30,000 continuous charge/discharge cycles. | Hao Niu Xue Yang Qian Wang Xiaoyan Jing Kui Cheng Kai Zhu Ke Ye Guiling Wang Dianxue Cao Jun Yan | 2020 | Journal of Energy Chemistry2020，29，7： | 6 |
| 8 | Discovery of marine fossils in the upper part of the Permian Linxi Formation in Lopingian, Xingmeng area, China显示文摘Two important geological issues have a long history of debate in the Xingmeng area.The first concerns the final closure of the North China plate,Siberia plate and several intermediate massifs in the area,and the other concerns the folding and lifting of the Xingmeng Trough.Disagreements arise because of issues involving the tectonicpalaeogeographical environment of the Upper Permian deposits of the Linxi Formation.The Linxi Formation(Upper Permian)is generally considered to be either an exclusively continental deposit or separated into marineterrigenous facies deposited during the Lower to Middle Linxi Period and continental deposits in the Upper Linxi Period.However,in this study,large numbers of bryozoan and sponge spicule fossils were discovered for this first time in the thick limestone layers and lenses of the upper part of the Linxi Formation found in the Guandi section of Linxi county in eastern Inner Mongolia.At the same time,abundant bryozoan fossils were also found in sedimentary tuff slices that were collected from the upper part of the Taohuayingzi Formation from the Taohuayingzi section in Ar Horqin Banner,and abundant small connecting body crinoid stem fossils were found in the dark shale of the Yangjiagou Formation from the Yangjiagou section of Jiutai county,Jilin Province.These marine fossils provide the first evidence that the Xingmeng area was still a marine or mainly marine environment at the end of the late Permian.This not only provides conclusive evidence for the recognition of the above two major geological issues but also promotes changes in the approach towards research,exploration and development of oil and gas,shale gas(oil),and other mineral resources that are preserved in the late Permian layers of the Northeast-Xingmeng area. | Yongsheng Zhang Shugang Tian Zishun Li Yuexuan Gong Enyuan Xing Zhuozhuo Wang Daxing Zhai Cao Jie Su Kui Wang Meng | 2014 | Chinese Science Bulletin2014，59，1： | 6 |
| 9 | Ultrahigh energy density battery-type asymmetric supercapacitors: NiMoO4 nanorod-decorated graphene and graphene/Fe2O3 quantum dots显示文摘 | Jiao Yang Wei Liu Hao Niu Kui Cheng Ke Ye Kai Zhu Guiling Wang Dianxue Cao Jun Yan | 2018 | Nano Research2018，11，9： | 5 |
| 10 | Uniformly grown PtCo-modified C03O4 nanosheets as a highly efficient catalyst for sodium borohydride electrooxidation显示文摘 | Congying Song Dongming Zhang Bin Wang Zhuang Cai Peng Yan Yang Sun Ke Ye Dianxue Cao Kui Cheng Guiling Wang | 2016 | Nano Research2016，9，11： | 5 |
| 11 | Wrinkled petals and stamens 1,is required for the morphogenesis of petals and stamens in Lotus japonicus显示文摘尽管许多进步在理解花的机关身份怎么在花的发展期间是坚定的被取得了,更少花的机关怎么在晚花的发展阶段被详细描述被知道。这里,我们描述新奇花的异种,起皱的花瓣和 stamens1 (wps1 ) ,它在花瓣和雄蕊的发展显示出缺点。基因分析显示那 wps1 异种相应于在染色体 3 的长手臂的一个单个后退的地点。在 wps1 异种的花的机关的早发展在野类型类似于那,并且异种的 malfunction 在晚发展的阶段开始,显示花瓣和雄蕊的外观上的一个缺点。在成熟的花,在异种的花瓣和雄蕊细丝被起皱或合拢,并且在花瓣和雄蕊细丝的 L1 层下面的细胞的形态学是反常的。花的机关身份基因的表达式模式没与野类型的相比在 wps1 异种被影响,这被发现,与所有花的机关的未改变的开发一致。而且,在花瓣的不同类型的表皮的房间的身份被维持。组织学的分析证明在 wps1 花,所有花瓣不规则地被合拢,并且在花瓣有系的结构,当内部房间的形状和安排畸形、未组织起来时。把结果基于这些,我们建议 Wps1 下游地行动到班 B 花的机关身份基因,并且工作在迟了的花期间调制细胞的区别发展阶段。 | Jiang Hua Chen Ji Liang Pang Li Lin Wang Yong Hai Luo Xin Li Xiang Ling Cao Kui Lin Wei Ma Xiao He Hu Da Luo | 2006 | Cell Research2006，16，5： | 4 |
| 12 | CO_(2) mineralization of carbide slag for the production of light calcium carbonates显示文摘The production of polyvinyl chloride by calcium carbide method is a typical chemical process with high coal consumption,leading to massive flue gas and carbide slag emissions.Currently,the carbide slag with high CaO content is usually stacked in residue field,easily draining away with the rain and corroding the soil.In this work,we coupled the treatment of flue gas and carbide slag to propose a facile CO_(2)mineralization route to prepare light calcium carbonate.And the route feasibility was comprehensively evaluated via experiments and simulation.Through experimental investigation,the Ca^(2+) leaching and mineralization reaction parameters were determined.Based on the experiment,a process was built and optimized through Aspen Plus,and the energy was integrated to obtain the overall process energy and material consumption.Finally,the net CO_(2)emission reduction rate of the entire process through the life-cycle assessment method was analyzed.Moreover,the relationship between the parameters and the CO_(2)emission life-cycle assessment was established.The final optimization results showed that the mineralization process required 1154.69 kW·h·(t CO_(2))^(-1) of energy(including heat energy of 979.32 kW·h·(t CO_(2))^(-1) and electrical energy of 175.37 kW·h·(t CO_(2))^(-1)),and the net CO_(2)emission reduction rate was 35.8%.The light CaCO_(3)product can be sold as a high value-added product.According to preliminary economic analysis,the profit of mineralizing can reach more than 2,100 CNY·(t CO_(2))^(-1). | Tongyang Zhang Guanrun Chu Junlin Lyu Yongda Cao Wentao Xu Kui Ma Lei Song Hairong Yue Bin Liang | 2022 | Chinese Journal of Chemical Engineering2022，35，3： | 4 |
| 13 | Characteristics of air quality in Tianjin during the Spring Festival period of 2015显示文摘To better understand the characteristics of air quality and the relationship between the chemical composition evolution and source variation,an intensive atmospheric campaign was conducted in Tianjin,a megacity of the North China Plain,from 10 February to 6 March 2015.There were 20 days exceeding the threshold value of secondary Chinese Ambient Air Quality Standards for PM2.5(75 μg m-3,daily average over 24 h)during the study period.Five air pollution episodes were selected for investigation.During the pre-holiday pollution episode,NH^+_4,NO^-_3,and SO^(2-)_4 were more abundant,indicating that air pollution was caused by motor vehicle exhaust emissions and coal consumption under unfavorable meteorological conditions.During Chinese Lunar New Year's Eve,widespread use of fireworks resulted in extremely high aerosol concentrations.Firework displays caused increases in K+ and also enrichment of SO^(2-)_4 relative to NO^-_3.The holiday pollution episode was caused by regional transport,characterized by abundant SO^(2-)_4 and NH^+_4.In addition,the aging processes of the particles from fireworks discharge played an important role in the formation of NO-3and SO^(2-)_4.The Lantern Festival episode was characterized by a transition from the enrichment of K+ to secondary inorganic ions(NO^-_3,SO^(2-)_4,and NH^+_4).The results of this study are useful for a detailed understanding of the variation in atmospheric compositions and sources caused by anthropogenic activity,and highlight the importance of controlling intensive fireworks discharge. | TANG Miao Jl Dong-Sheng GAO Wen-Kang YU Zhong-Wang CHEN Kui CAO Wan | 2016 | Atmospheric and Oceanic Science Letters2016，9，1： | 4 |
| 14 | Pharmacokinetic interactions between ilaprazole and clarithromycin following ilaprazole, clarithromycin and amoxicillin triple therapy显示文摘瞄准: 调查在 ilaprazole,一个新质子泵禁止者,和 clarithromycin 追随者 ilaprazole 之间的药相互作用, clarithromycin 和 amoxicillin 联合治疗。 | Shan CAO Gan ZHOU Dong-sheng OU-YANG Hui-zi WU Kui XIAO Yao CHEN Dong GUO Lan FAN Zhi-rong TAN Hai-tang HU Xiang-hong QIN Hong-hao ZHOU Wei ZHANG | 2012 | Acta Pharmacologica Sinica2012，33，8： | 4 |
| 15 | Establishment of a blunt impact-induced brain injury model in rabbits显示文摘 | LI Kui CAO Yun-xing YANG Yong-qiang YIN Zhi-yong ZHAO Hui WANG Li-jun | 2012 | Chinese Journal of Traumatology2012，15，2： | 3 |
| 16 | Designandconstructionof athree-dimensionalelectrodewith biomass-derived carbon current collector andwater-soluble binder for high-sulfur-loading lithium-sulfur batteries显示文摘Lithium-sulfur batteries attract lots of attention due to their high specific capacity,low cost,and environmental friendliness.However,the low sulfur utilization and short cycle life extremely hinder their application.Herein,we design and fabricate a three-dimensional electrode by a simple filtration method to achieve a high-sulfur loading.Biomass porous carbon is employed as a current collector,which not only enhances the electronic transport but also effectively limits the volume expansion of the active material.Meanwhile,an optimized carboxymethyl cellulose binder is chosen.The chemical bonding restricts the shuttle effect,leading to improved electrochemical performance.Under the ultrahigh sulfur load of 28mg/cm2,the high capacity of 18mAh/cm2 is still maintained,and stable cycling performance is obtained.This study demonstrates a viable strategy to develop promising lithium-sulfur batteries with a three-dimensional electrode,which promotes sulfur loading and electrochemical performance. | Pengfei Wang Zhe Gong Ke Ye Vipin Kumar Kai Zhu Linna Sha Jun Yan Jinling Yin Kui Cheng Guiling Wang Dianxue Cao | 2020 | Carbon Energy2020，2，4： | 3 |
| 17 | Preparation of Molecular Imprinted Copolymer Membrane for Uracil Recognition显示文摘Uracil molecular imprinted membrane was prepared by phase inversion technique with [P(AN-co-MAA)] copolymer. SEM photograph shows that the resultant membrane has a typical ultrafiltration structure with Water Volume Flux of 3.7?0-5m3/m2穝, and uracil substrate permeation experiment shows that the resultant membrane can bind uracil into its structure, and shows a binding equilibrium. | Shao Ling XIA, Hong Ying WANG*, Hong SUN, Yu Kun LIU, Shao Kui CAO Material Engineering School of Zhengzhou University, Zhengzhou 450052 | 2003 | Chinese Chemical Letters2003，14，8： | 3 |
| 18 | Induced Th2 dominant immune response in APPswe, PSEN1dE9 transgenic mice after nasal immunization with an adenoviral vector encoding 10 tandem repeats of beta-amyloid 3-10显示文摘Immunotherapy for Alzheimer's disease (AD) is effective in improving cognitive function in transgenic mouse models of AD. Because the AN1792 [beta-amyloid (Aβ) 1-42] vaccine was halted because of T cell mediated meningoencephalitis, many scientists are searching for a novel vaccine to avoid the T cell mediated immune response caused by the Aβ1-42. Importantly, the time when the immunization is begun can influence the immune effect. In this study, an adenovirus vaccine was constructed containing 10 × Aβ3-10 repeats and gene adjuvant CpG DNA. Transgenic AD mice were immunized intranasally for 3 months. After 10 × Aβ3-10 vaccine immunization, high titers of anti-Aβ42 IgG1 predominant antibodies were induced. In spatial learning ability and probe tests, the 10 × Aβ3-10 immunized mice showed significantly improved memories compared to control mice. The 10 × Aβ3-10 vaccine resulted in a robust Th2 dominant humoral immune response and reduced learning deficits in AD mice. In addition, the 10 × Aβ3-10 vaccine might be more efficient if administered before Aβ aggregation at an early stage in the AD mouse brain. Thus, the adenovirus vector encoding 10 × Aβ3-10 is a promising vaccine for AD. | Rong Guo Kui Huang Tongzi Jiang Jian Li Yu Li Xiaona Xing Yunpeng Cao | 2011 | Neural Regeneration Research2011，6，26： | 2 |
| 19 | Organic 3D interconnected graphene aerogel as cathode materials for high-performance aqueous zinc ion battery显示文摘Aqueous rechargeable zinc ion batteries are very attractive in large-scale storage applications,because they have high safety,low cost and good durability.Nonetheless,their advancements are hindered by a dearth of positive host materials(cathode)due to sluggish diffusion of Zn2+in the solid inorganic frameworks.Here,we report a novel organic electrode material of poly 3,4,9,10-perylentetracarboxylic dianhydride(PPTCDA)/graphene aerogel(GA).The 3D interconnected porous architecture synthesized through a simple solvothermal reaction,where the PPTCDA is homogenously embedded in the GA nanosheets.The self-assembly of PPTCDA/GA coin-type cell will not only significantly improve the durability and extend lifetime of the devices,but also reduce the electronic waste and economic cost.The self-assembled structure does not require the auxiliary electrode and conductive agent to prepare the electrode material,which is a simple method for preparing the coin-type cell and a foundation for the next large-scale production.The PPTCDA/GA delivers a high capacity of≥200 m Ah g^–1 with the voltage of 0.0~1.5 V.After 300 cycles,the capacity retention rate still close to 100%.The discussion on the mechanism of Zn2+intercalation/deintercalation in the PPTCDA/GA electrode is explored by Fourier transform infrared spectrometer(FT-IR),X-ray diffraction(XRD)and X-ray photoelectron spectroscopy(XPS)characterizations.The morphology and structure of PPTCDA/GA are examined by scanning electron microscopy(SEM)and transmission electron microscopy(TEM). | Ruibai Cang Ke Ye Kai Zhu Jun Yan Jinling Yin Kui Cheng Guiling Wang Dianxue Cao | 2020 | Journal of Energy Chemistry2020，29，6： | 2 |
| 20 | Skull metastasis revealing a papillary thyroid carcinoma显示文摘Although thyroid carcinoma is a relatively common form of malignancy,metastatic spread to the skull is rare.Here,we report a case of papillary thyroid carcinoma with frontal and parietal metastasis.A61-year-old Chinese woman presented with a one year history of a growing mass on the center of the frontal and parietal bone,initially thought to be meningioma.Biopsy of the skull base mass after intracalvarium excision,indicated a tumor of thyroid origin.One month later the patient underwent a total thyroidectomy.Pathological examination confirmed a diagnosis of papillary thyroid carcinoma with frontal and parietal bone metastasis.Based on this experience,the key to successful management of the skull metastasis of thyroid carcinoma is prompt diagnosis and appropriate treatment.Skull metastasis should be considered at the outset of the clinical course of papillary thyroid cancer.To facilitate this,patients should be meticulously investigated by a multidisciplinary team to improve quality of life. | Xi Li Ge Zhao Yong Zhang Kui Ding Hui Cao Dehua Yang Jian Zhang Zhiquan Duan Shijie Xin | 2013 | Chinese Journal of Cancer Research2013，25，5： | 2 |
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