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| 1 | Spectrum of final pathological diagnosis of gastric adenoma after endoscopic resection显示文摘AIM: To investigate how many discrepancies occur in patients before and after endoscopic treatment of referred adenoma and the reason for these results. METHODS: We retrospectively reviewed data from 554 cases of 534 patients who were referred from primary care centres for adenoma treatment and treated for endoscopic mucosal resection (EMR) or endoscopic submucosal dissection (ESD) at Chungnam National University Hospital, from July 2006 to June 2009. Reendoscopy was examined in 142 cases and biopsywas performed in 108 cases prior to treatment. Three endoscopists (1, 2 and 3) performed all EMRs or ESDs and three pathologists (1, 2 and 3) diagnosed most of the cases. Transfer notes, medical records and endoscopic pictures of these cases were retrospectively reviewed and analyzed. RESULTS: Adenocarcinoma was 72 (13.0%) cases in total 554 cases after endoscopic treatment of referred adenoma. When the grade of dysplasia was high (55.0%), biopsy number was more than three (22.7%), size was no smaller than 2.0 cm (23.2%), morphologic type was depressed (35.8%) or yamada type Ⅳ (100%), and color was red (30.9%) or mixed-or-undetermined (25.0%), it had much more malignancy rate than the others (P < 0.05). All 18 cases diagnosed as adenocarcinoma in the re-endoscopic forceps biopsy were performed by endoscopist 1. There were different malignancy rates according to the pathologist (P = 0.027). CONCLUSION: High grade dysplasia is the most important factor for predicting malignancy as a final pathologic diagnosis before treating the referred gastric adenoma. This discrepancy can occur mainly through inappropriately selecting a biopsy site where cancer cells do not exist, but it also depends on the pathologist to some extent. | Kwan Woo Nam Kyu Sang Song Heon Young Lee Byung Seok Lee Jae Kyu Seong Seok Hyun Kim Hee Seok Moon Eaum Seok Lee Hyun Yong Jeong | 2011 | World Journal of Gastroenterology2011，17，47： | 2 |
| 2 | Genetic variations in the PRKAA1 and ZBTB20 genes and gastric cancer susceptibility in a Korean population显示文摘 | Hye‐Rim Song Hee Nam Kim Sun‐Seog Kweon Jin‐Su Choi Hyun Jeong Shim Sang Hee Cho Ik Joo Chung Young‐Kyu Park Soo Hyun Kim Yoo‐Duk Choi Kyung Woong Joo Min‐Ho Shin | 2013 | Mol Carcinog2013，，1： | 2 |
| 3 | Aberrant upregulation of ASCL 2 by promoter demethylation promotes the growth and resistance to 5‐fluorouracil of gastric cancer cells显示文摘 | Oh‐Hyung Kwon Jong‐Lyul Park Su‐Jin Baek Seung‐Moo Noh Kyu‐Sang Song Seon‐Young Kim Yong Sung Kim | 2013 | Cancer Sci2013，，3： | 2 |
| 4 | Autologous Adipose Tissue‐Derived Stem Cells Treatment Demonstrated Favorable and Sustainable Therapeutic Effect for Crohn’s Fistula显示文摘 | Woo Yong Lee Kyu Joo Park Yong Beom Cho Sang Nam Yoon Kee Ho Song Do Sun Kim Sang Hun Jung Mihyung Kim Hee‐Won Yoo Inok Kim Hunjoo Ha Chang Sik Yu | 2013 | Stem Cells2013，，11： | 2 |
| 5 | Serum highly selective C-reactive protein concentration is associated with the volume of ischemic tissue in acute ischemic stroke显示文摘 | Chun Song Youn Seung Pill Choi Soo Hyun Kim Sang Hoon Oh Won Jung Jeong Han Joon Kim Kyu Nam Park | 2012 | American Journal of Emergency Medicine2012，，1： | 1 |
| 6 | Effect of the Injection Parameters on Diesel Spray Characteristics显示文摘 | Kyu Keun Song Sang Cherl Sim | | 0，，06： | 1 |
| 7 | Epigenetic changes in estrogen receptor β gene in atherosclerotic cardiovascular tissues and in-vitro vascular senescence显示文摘 | Jei Kim Jee Yeon Kim Kyu Sang Song Young Ho Lee Joong Seok Seo Jaroslav Jelinek Pascal J. Goldschmidt-Clermont Jean-Pierre J. Issa | 2006 | BBA - Molecular Basis of Disease2006，，1： | 1 |
| 8 | Aberrant upregulation of ASCL 2 by promoter demethylation promotes the growth and resistance to 5‐fluorouracil of gastric cancer cells显示文摘 | Oh‐Hyung Kwon Jong‐Lyul Park Su‐Jin Baek Seung‐Moo Noh Kyu‐Sang Song Seon‐Young Kim Yong Sung Kim | 2013 | Cancer Sci2013，，3： | 1 |
| 9 | Effects of isolating methods (mechanical or enzymatical) on structure of pre-antral follicles in mouse显示文摘 | Kee Sang Park Taek Hoo Lee Yoon Kyu Park Hai Bum Song Sang Sik Chun | 2005 | Journal of Assisted Reproduction and Genetics (-)2005，，9： | 1 |
| 10 | The complex of Fas-associated factor 1 with Hsp70 stabilizes the adherens junction integrity by suppressing RhoA activation显示文摘Fas-associated factor 1 (FAF1) is a scaffolding protein that plays multiple functions, and dysregulation of FAF1 is associated withmany types of diseases such as cancers. FAF1 contains multiple ubiquitin-related domains (UBA, UBL1, UBL2, UAS, and UBX), eachdomain interacting with a specific partner. In particular, the interaction of UBL1 with heat shock protein 70 (Hsp70) is associatedwith tumor formation, although the molecular understanding remains unknown. In this study, the structural analysis revealed thatHis160 of FAF1 is important for its interaction with Hsp70. The association of Hsp70 with FAF1 is required for the interaction withIQGAP1. FAF1 negatively regulates RhoA activation by FAF1–Hsp70 complex formation, which then interacts with IQGAP1. Thesesteps play a key role in maintaining the stability of cell-to-cell junction. We conclude that FAF1 plays a critical role in the structureand function of adherens junction during tissue homeostasis and morphogenesis by suppressing RhoA activation, which induces theactivation of Rho-associated protein kinase, phosphorylation of myosin light chain, formation of actin stress fiber, and disruptionof adherens junction. In addition, depletion of FAF1 increased collective invasion in a 3D spheroid cell culture. These results provideinsightinto how the FAF1–Hsp70 complex acts as a novelregulator ofthe adherens junction integrity. The complex can be a potentialtherapeutic target to inhibit tumorigenesis and metastasis. | Soonhwa Song Joon Kyu Park Sang Chui Shin Jae-Jin Lee Seung Kon Hong In-Kang Song Bokyung Kim Eun Joo Song Kong-Joo Lee Eunice EunKyeong Kim | 2022 | Journal of Molecular Cell Biology2022，14，6： | 1 |
| 11 | The HSP90-SGT1-RAR1 molecular chaperone complex: a core modulator in plant immunity显示文摘 | Young Su Seo Sang Kyu Lee Min Young Song | 2008 | J Plant Biology2008，51，： | 1 |
| 12 | High-efficiency single and tandem fullerene solar cells with asymmetric monofluorinated diketopyrrolopyrrole-based polymer显示文摘Design and synthesis of low bandgap(LBG) polymer donors is inevitably challenging and their processability from a non-halogenated solvent system remains a hurdle to overcome in the area of highperformance polymer solar cells(PSCs).Due to a high aggregation tendency of LBG polymers,especially diketopyrrolopyrrole(DPP)-based polymers coupled with bithiophenes in the polymer backbones,their widespread adoption in non-ha logena ted solvent-processed PSCs has been limited.Herein,a novel LBG DPP-based polymer,called PDPP4 T-1 F with asymmetric arrangement of fluorine atom,has been successfully synthesized and showed an outstanding power conversion efficiency(PCE) of 10.10% in a singlejunction fullerene-based PSCs.Furthermore,an impressive PCE of 13.21% has been achieved in a tandem device from a fully non-halogenated solvent system,which integrates a wide bandgap PDTBTBz-2 F polymer in the bottom cell and LBG PDPP4 T-1 F polymer in the top cell.The achieved efficiency is the highest value reported in the literature to date in fullerene-based tandem PSCs.We found that a uniformly distributed interpenetrating fibril network with nano-scale phase separation and anisotropy of the polymer backbone orientation for efficient charge transfer/transport and suppressed charge recombination in PDPP4 T-1 F-based PSCs led to outstanding PCEs in single and tandem-junction PSCs. | Shafket Rasool Quoc Viet Hoang Doan Van Vu Chang Eun Song Hang Ken Lee Sang Kyu Lee Jong-Cheol Lee Sang-Jin Moon Won Suk Shin | 2022 | Journal of Energy Chemistry2022，31，1： | 0 |
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