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9篇 您的检索式:作者名="Kyungwon Lee"
    题名 作者 年代 出处 被引量
1Moxibustion for treating menopausal hot flashes: a randomized clinical trial显示文摘Ji-Eun Park Myeong Soo Lee Soyoung Jung Aeran Kim Kyungwon Kang Junyong Choi Jongbae Park Sun-Mi Choi 2009Menopause2009,,4:1
2Novel acquired metallo-β-lactamase gene, blaSIM-1,in a class 1 Integron from Acinetobacter baumannii clinical isolates from Korea显示文摘Kyungwon Lee Jong Hwa Yum Dongeun Yong 2005Antimlcrobial Agents and Chemotherapy2005,49,11:1
3Imipenem-EDTA Disk Method for Differentiation of Metallo-Lactamase-Producing Clinical Isolates of Pseudomonas spp and Acinetobacter spp显示文摘Dongeun Yong Kyungwon Lee Jong Hwa Yum 0,,:1
4Vibration test of 5-storey steel frame with viscoelastic dampers 显示文摘KYUNGWON MIN JINKOO KIM SANGHYUN LEE 2004Engineering Structures2004,26,:1
5Species Distribution and Susceptibility to Azole Antifungals of Candida Bloodstream Isolates from Eight University Hospitals in Korea显示文摘Jin-Sol Lee Jong Hee Shin Kyungwon Lee 2007Yonsei Medical Journal2007,48,5:1
6Prevalence and diversity of carbapenemases among imipenem-nonsusceptible Acinetobacter isolates in Korea: emergence of a novel OXA-182显示文摘Chang-Ki Kim Yangsoon Lee Hyukmin Lee Gun-Jo Woo Wonkeun Song Mi-Na Kim Wee-Gyo Lee Seok Hoon Jeong Kyungwon Lee Yunsop Chong 2010Diagnostic Microbiology & Infectious Disease2010,,4:1
7The effect ofleakage on the acoustic performance of reactive silencers显示文摘Iljae Lee Kyungwon Jeon Jaebyung Park 2013Applied Acoustics2013,74,4:1
8Reprogramming of cancer-associated fibroblasts by apoptotic cancer cells inhibits lung metastasis via Notch1-WISP-1 signaling显示文摘The interplay between apoptotic cancer cells and the tumor microenvironment modulates cancer progression and metastasis.Cancer-associated fibroblasts(CAFs)play a crucial role in promoting these events through paracrine communication.Here,we demonstrate that conditioned medium(CM)from lung CAFs exposed to apoptotic cancer cells suppresses TGF-β1-induced migration and invasion of cancer cells and CAFs.Direct exposure of CAFs to apoptotic 344SQ cells(ApoSQ)inhibited CAF migration and invasion and the expression of CAF activation markers.Enhanced secretion of Wnt‐induced signaling protein 1(WISP-1)by CAFs exposed to ApoSQ was required for these antimigratory and anti-invasive effects.Pharmacological inhibition of Notch1 activation or siRNA-mediated Notch1 silencing prevented WISP-1 production by CAFs and reversed the antimigratory and anti-invasive effects.Enhanced expression of the Notch ligand delta-like protein 1 on the surface of ultraviolet-irradiated apoptotic lung cancer cells triggered Notch1-WISP-1 signaling.Phosphatidylserine receptor brain-specific angiogenesis inhibitor 1(BAI1)-Rac1 signaling,which facilitated efferocytosis by CAFs,participated in crosstalk with Notch1 signaling for optimal production of WISP-1.In addition,a single injection of ApoSQ enhanced WISP-1 production,suppressed the expression of CAF activation markers in isolated Thy1^(+)CAFs,and inhibited lung metastasis in syngeneic immunocompetent mice via Notch1 signaling.Treatment with CM from CAFs exposed to ApoSQ suppressed tumor growth and lung metastasis,whereas treatment with WISP-1-immunodepleted CM from CAFs exposed to ApoSQ reversed the antitumorigenic and antimetastatic effects.Therefore,treatment with CM from CAFs exposed to apoptotic lung cancer cells could be therapeutically applied to suppress CAF activation,thereby preventing cancer progression and metastasis.Hee Ja Kim Kyungwon Yang Kiyoon Kim Ye‐Ji Lee Sieun Lee Sung Yong Ahn Young‐Ho Ahn Jihee Lee Kang 2022Cellular & Molecular Immunology2022,19,12:0
9Hyundai—Kia运动型多功能车用V6—3L柴油机的研发显示文摘为了满足高级运动型多功能车的要求,新开发了一款V6—3L柴油机。该发动机的有效功率提供了良好的行驶舒适性,并达到欧4排放标准。通过燃烧和排气后处理方案的优化,该发动机的基本设计方案可成为未来达到欧5排放标准的基础。同时,为了满足美国Tier 2 Bin 5排放标准的要求,正在开发采用尿素喷射的氮氧化物排气后处理系统。Yohan Chi 2009国外内燃机2009,,5:0
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