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| 1 | Ultrastable single-atom gold catalysts with strong covalent metal-support interaction (CMSI)显示文摘Supported noble metal nanoparticles (including nanoclusters) are widely used in many industrial catalytic processes. While the finely dispersed nanostructures are highly active, they are usually thermodynamically unstable and tend to aggregate or sinter at elevated temperatures. This scenario is particularly true for supported nanogold catalysts because the gold nanostructures are easily sintered at high temperatures, under reaction conditions, or even during storage at ambient temperature. Here, we demonstrate that isolated Au single atoms dispersed on iron oxide nanocrystallites (Aul/FeOx) are much more sintering- resistant than Au nanostructures, and exhibit extremely high reaction stability for CO oxidation in a wide temperature range. Theoretical studies revealed that the positively charged and surface-anchored Aul atoms with high valent states formed significant covalent metal-support interactions (CMSIs), thus providing the ultra-stability and remarkable catalytic performance. This work may provide insights and a new avenue for fabricating supported Au catalysts with ultra-high stability. | Botao Qiao Jin-Xia Liang Aiqin Wang Cong-Qiao Xu Jun Li Tao Zhang Jingyue (Jimmy) Liu | 2015 | Nano Research2015，8，9： | 30 |
| 2 | MicroRNA expression profiling in diabetic GK rat model显示文摘MicroRNAs (miRNAs ) 是小搁浅单人赛的非编码的 RNA 的一个最新识别的班,经由 post-transcriptional 调整他们的目标基因小径。miRNAs 在许多生物过程起重要作用,这被证明了。为了更好理解 miRNA,在类型 2 糖尿病上工作,我们使用了 oligonucleotide microarray 监视 GotoKakizaki (GK ) 和 Wistar 老鼠的骨胳的肌肉的 miRNA 表达式侧面。七 miRNAs 是下面表示的,二 miRNAs 在 GK 老鼠的肌肉是过去表示的,这被发现。在他们之中, miR-24 显示出最突出的变化。p38 MAPK,是 miR-24 的一个直接目标,也显示出表示差别。所有数据给 miR-24 可能通过 p38 MAPK 的下面规定与糖尿病被联系的线索。 | Bing Huang Wenming Qin Botao Zhao Yi Shi Chengguo Yao Jin Li Huasheng Xiao Youxin Jin | 2009 | Acta Biochimica et Biophysica Sinica2009，41，6： | 17 |
| 3 | MiR-181a-5p inhibits cell proliferation and migration by targeting Kras in non-small cell lung cancer A549 cells显示文摘MicroRNAs 玩在 carcinogenesis 和肿瘤的重要角色进行。肺癌症是世界范围的癌症死亡的领先的原因。在这研究, miR-181a-5p 的功能在 non-small-cell 肺癌症(NSCLC ) 被调查。结果证明 miR-181a-5p 显著地在 NSCLC 纸巾和房间线被减少。有 miR-181a-5p 的 A549 房间 transfected 的增长和迁居模仿显著地被禁止。酶活动试金结果证明 Kras 的二个有约束力的地点能被 miR-181a-5p 直接指向。而且, Kras 由在 transcriptional 和翻译层次的 miR-181a-5p 是下面调整的。调停 SiRNA 的 Kras 下面规定能模仿 miR-181a-5p 的效果在 A549 模仿房间。我们的调查结果建议 miR-181a-5p 由部分指向 Kras 在肿瘤抑制起一个潜在的作用并且在 NSCLC 病人有潜在的治疗学的申请。 | Zhongliang Ma Xiang Qiu Detao Wang Yanli Li Bingjie Zhang Tianwei Yuan Jiali Wei Botao Zhao Xintai Zhao Jiatao LOU Yan Jin Youxin Jin | 2015 | Acta Biochimica et Biophysica Sinica2015，47，8： | 8 |
| 4 | Atomic Co/Ni dual sites with N/P-coordination as bifunctional oxygen electrocatalyst for rechargeable zinc-air batteries显示文摘Metal-nitrogen-carbon(M-N-C)single-atom catalysts exhibit desirable electrochemical catalytic properties.However,the replacement of N atoms by heteroatoms(B,P,S,etc.)has been regarded as a useful method for regulating the coordination environment.The structure engineered M-N-C sites via doping heteroatoms play an important role to the adsorption and activation of the oxygen intermediate.Herein,we develop an efficient strategy to construct dual atomic site catalysts via the formation of a Co_(1)-PN and Ni1-PN planar configuration.The developed Co_(1)-PNC/Ni1-PNC catalyst exhibits excellent bifunctional electrocatalytic performance in alkaline solution.Both experimental and theoretical results demonstrated that the N/P coordinated Co/Ni sites moderately reduced the binding interaction of oxygen intermediates.The Co_(1)-PNC/Ni1-PNC endows a rechargeable Zn-air battery with excellent power density and cycling stability as an air-cathode,which is superior to that of the benchmark Pt/C+IrO_(2).This work paves an avenue for design of dual single-atomic sites and regulation of the atomic configuration on carbon-based materials to achieve high-performance electrocatalysts. | Botao Hu Aijian Huang Xuejiang Zhang Zheng Chen Renyong Tu Wei Zhu Zhongbin Zhuang Chen Chen Qing Peng Yadong Li | 2021 | Nano Research2021，14，10： | 6 |
| 5 | BMPRII is a direct target of miR-21显示文摘MicroRNAs (miRNAs ) 是在 post-transcriptional 阶段调整血缘的 mRNA 表情的小非编码的 RNA 的一种类型。尽管几 miRNAs 被知道涉及各种各样的生物进程,包括发展预定, patterning, embryogenesis,区别和 organogenesis,生长控制,和 apoptosis,许多目标基因和大多数 miRNAs 的函数仍然是不清楚的。因为仅仅在动物房间在 miRNAs 和他们的目标之间有部分补充,为给定的 miRNA 识别特定的目标基因并且阐明是困难的它的功能。在这研究,我们证实了形态基因的蛋白质受体 II (BMPRII ) 是的那根骨头 miR-21 的一个直接目标,并且也证明 BMPRII 的蛋白质水平在 PC3 和 Lncap 房间与 miR-21 的数量相反地相关。这些调查结果建议 miR-21 可以在由调整 BMPRII 的表示调整恶意和前列腺癌症房间并且在干细胞的自强的变形能力有一个潜在的角色。 | Wenming Qin Botao Zhao Yi Shi Chengguo Yao Li Jin Youxin Jin | 2009 | Acta Biochimica et Biophysica Sinica2009，41，7： | 5 |
| 6 | MicroRNA expression profiling during neural differentiation of mouse embryonic carcinoma P19 cells显示文摘MicroRNAs (或 miRNAs ) 是涉及与房间的发展和区别有关的大量活动的小非编码的 RNA (2125 核苷酸) 。区分的神经干细胞的有那些的鼠标 P19 胚胎的癌房间的 miRNA 表达式侧面的比较证明表达式在区别以后 65 铺平改变的 miRNAs (2 褶层) 。MiR-124a 是戏剧性地起来调整的(超过 20 褶层) 当在 miR-290295 簇的 miR-302 家庭和那些的 miRNAs 是强烈下面调整的时。进一步的分析表明象 Oct4 和 Sox2 那样的一些重要因素看起来涉及这些 miRNAs 的规定。这些结果可以在早老鼠胚胎贡献调整 miRNA 的神经区别的更好的理解。 | Bing Huang Wei Li Botao Zhao Caihong Xia Ruqiang Liang Kangcheng Ruan Naihe Jing Youxin Jin | 2009 | Acta Biochimica et Biophysica Sinica2009，41，3： | 5 |
| 7 | Development of a low-cost detection method for miRNA microarray显示文摘MicroRNA (miRNA ) microarray 是一个强大的工具探索 miRNA 介绍的表示。在 miRNA microarray 使用的当前的察觉方法主要是基于的荧光,它通常要求象激光那样的昂贵的察觉系统几万美元的共焦的扫描仪。最近,我们基于连接酶的试金为 miRNA microarray 开发了一个便宜还敏感的察觉方法。在这条途径, biotinylated miRNAs 被在 microarray 上使不能调动的探针滑动的相应 oligonucleotide 捕获;然后 biotinylated miRNAs 将捕获结合 streptavidin 的碱的磷酸酶。每个 biotinylated miRNA 点上的紫色黑色猛冲被酶生产催化反应。它能被数字照相机在一台显微镜上装了的一台电荷耦合的设备容易检测,它降低与荧光方法的相比花去超过 100 褶层的察觉。我们的数据与 biotinylated miRNA 集中和察觉限制显示出点相互关联的那信号紧张很好因为 miRNAs 是动态范围跨越的至少 0.4 fmol 和察觉大约 2.5 个数量级,它比得上荧光方法的。 | Wei Li Botao Zhao Youxin Jin Kangcheng Ruan | 2010 | Acta Biochimica et Biophysica Sinica2010，42，4： | 3 |
| 8 | Highway Planning and Design in the Qinghai–Tibet Plateau of China: A Cost–Safety Balance Perspective显示文摘Engineering designs for mountainous highways emphasize compliance checking to ensure safety. However, relying solely on compliance checking may lead designers to minimize costs at the expense of high risk indicators, since the overall risk level of the highway design is unknown to the designers. This paper describes a method for the simultaneous consideration of traffic safety risks and the associated cost burden related to the appropriate planning and design of a mountainous highway. The method can be carried out in four steps: First, the highway design is represented by a new parametric framework to extract the key design variables that affect not only the life-cycle cost but also the operational safety. Second, the relationship between the life-cycle cost and the operational safety risk factors is established in the cost-estimation functions. Third, a fault tree analysis (FTA) is introduced to identify the traffic risk factors from the design variables. The safety performance of the design solutions is also assessed by the generalized linear-regression model. Fourth, a theory of acceptable risk analysis is introduced to the traffic safety assessment, and a computing algorithm is proposed to solve for a cost-efficient optimal solution within the range of acceptable risk, in order to help decision-makers. This approach was applied and examined in the Sichuan–Tibet Highway engineering project, which is located in a complex area with a large elevation gradient and a wide range of mountains. The experimental results show that the proposed approach significantly improved both the safety and cost performance of the project in the study area. | Chengqian Li Lieyun Ding Botao Zhong | 2019 | Engineering2019，5，2： | 3 |
| 9 | StInvInh2 as an inhibitor of Stvac INV 1 regulates the cold‐induced sweetening of potato tubers by specifically capping vacuolar invertase activity显示文摘 | Xun Liu Yuan Lin Jun Liu Botao Song Yongbin Ou Huiling Zhang Meng Li Conghua Xie | 2013 | Plant Biotechnol J2013，，5： | 2 |
| 10 | Cloning of Novel Repeat-associated Small RNAs Derived from Hairpin Precursors in Oryza sativa显示文摘包括 microRNAs (miRNAs ) 种小非编码的 RNA,小介入 RNA (siRNAs ) 和交易的 siRNAs,在房间在 modulating 基因表达起重要作用。这里,我们孤立 21 个新奇内长的小 RNA 分子,从 18 ~ 24 核苷酸,在能被印射到 111 位发卡先锋的 Oryza sativa。进一步的分析显示大多数这些发卡序列从通常认为的缩小的转换重复的 transposable 元素发源, miRNA 内长的 siRNAs 经常是的像发卡的先锋和植物是特征的 DNA transposon.Considering 的一种主要类型在转座子定位了区域,我们假设了我们的克隆的小 RNA 可能在在 siRNAs 和 miRNAs.Northern 污点分析之间的进化进程代表中间的产品,这显示他们中的五个更富有地与另外的纸巾相比在花被表示,在开花期暗示他们的潜在的函数。在结论,我们的结果充实米饭小 RNA 数据并且在植物为小 RNA 注解提供一个有意义的观点。 | Chengguo YAO Botao ZHAO Wei LI Yang LI Wenming QIN Bing HUANG Youxin JIN | 2007 | Acta Biochimica et Biophysica Sinica2007，39，11： | 2 |
| 11 | MiR-200a is involved in rat epididymal development by targeting β-catenin mRNA显示文摘在到成年人的从出生后的开发的老鼠的 epididymis 的 350 microRNAs (miRNAs ) 的表达式(从出生后的天 770 ) 与自制 miRNA microarray 被介绍。在他们之中, 48 miRNAs 显著地变化了,在哪个 miR-200a 的表示与时间显然增加了,在与从北污点分析获得了那的一个好协议。即时量聚合酶的链反应结果显示老鼠 -catenin 的那时间的表情确切在老鼠 epididymal 开发期间是到 miR-200a 的 inversed,暗示 miR-200a 可能也指向在由 Saydam 等报导了的老鼠 epididymis 的 -catenin mRNA。在人。生物信息的分析显示老鼠 -catenin mRNA 的 3 untranslated 区域确实为 miR-200a 包含了一个通常认为的有约束力的地点。同时,这个有约束力的地点的顺序与有二邻近的核苷酸(U 和 C ) 的删除的人的 -catenin mRNA 的不同,这被发现。但是在老鼠 NRK 房间在 HEK 293T 房间和 miR-200a 的 overexpression 指向试金的酶的结果证明 miR-200a 确实指向了老鼠 -catenin mRNA 并且引起它的表示的抑制。所有这些结果证明 miR-200a 应该被指向老鼠的 -catenin mRNA 并且压制它的表达式涉及老鼠 epididymal 开发。 | Xiaojiang Wu Botao Zhao Wei Li Yue Chen Ruqiang Liang Lin Li Youxin Jin Kangcheng Ruan | 2012 | Acta Biochimica et Biophysica Sinica2012，44，3： | 2 |
| 12 | A printed dual-wideband magneto-electric dipole antenna for WWAN/ LTE applications显示文摘 | FENG Botao LI Shufang AN Wenxing | 2014 | International Journal of Electronics and Communications2014，68，10： | 1 |
| 13 | Total phenolic contents andantioxidant capacities of herbal and tea infusions显示文摘 | FU Li XU Botao XU Renyou | 2011 | Int J Mol Sci2011，12，4： | 1 |
| 14 | Enhanced stability of Pt/Al_(2)O_(3) modified by Zn promoter for catalytic dehydrogenation of ethane显示文摘Catalytic ethane dehydrogenation(EDH) to ethylene over Pt-based catalysts has received increasing interests in recent years as it is a potential alternative route to conventional steam cracking. However, the catalysts used in this reaction often suffer from rapid deactivation due to serious coke deposition and metal sintering. Herein, we reported the effects of Zn modification on the stability of Pt/Al2 O3 for EDH.The Zn-modified sample(PtZn2/Al2 O3) exhibits stable ethane conversion(20%) with over 95% ethylene selectivity. More importantly, it exhibits a significantly low deactivation rate of only 0.003 h-1 at 600 °C for70 h, which surpasses most of previously reported catalysts. Detailed characterizations including in situ FT-IR, ethylene adsorption microcalorimetry, and HAADF-STEM etc. reveal that Zn modifier reduces the number of Lewis acid sites on the catalyst surface. Moreover, it could modify Pt sites and preferentially cover the step sites, which decrease surface energy and retard the sintering of Pt particle, then prohibiting the further dehydrogenation of ethylene to ethylidyne. Consequently, the good stability is realized due to anti-sintering and the decrease of coke formation on the Pt Zn2/Al2 O3 catalyst. | Xiaoyu Li Yanliang Zhou Botao Qiao Xiaoli Pan Chaojie Wang Liru Cao Lin Li Jian Lin Xiaodong Wang | 2020 | Journal of Energy Chemistry2020，29，12： | 1 |
| 15 | Formal analysis of timeli- ness undeniable protocols time limitation 显示文摘 | Li Botao Luo Junzhou | 2011 | Journal of Software2011，17，5： | 1 |
| 16 | Study of an iron-manganese Fischer-Tropsch synthesis catalyst promoted with copper显示文摘 | Zhang Chenghua Li Yongwang Teng Botao | 2006 | Journal of Catalysis2006，237，1： | 1 |
| 17 | Expression and characterization of rice putative PAUSED gene显示文摘在 Arabidopsis,暂停了(PSD ) 编码 los1p/exportin-t 的 ortholog,它调停在酵母和哺乳动物的转移 RNA (tRNA ) 的原子出口。在象米饭那样的 monocot 植物,然而,相应 ortholog 的知识被限制,并且它在生长开发和生产率的效果仍然保持未知。在这研究,我们验证了一根米饭 transfer-DNAinsertional 异种 psd 线并且分析了它的显型;异种与野类型的米饭相比包括延迟的开发和低富饶显示了严重词法缺点。与在野类型、变异的叶织物之间的北污点分析在细胞质、原子的部分检验 intronless tRNA-Tyr 和包含 intron pre-tRNA-Ala 表示层次建议米饭 PSD 可能从原子核涉及 tRNA 出口到细胞质。另外,反向的抄写聚合酶链反应分析表明那个 PSD 抄本在整个正常米饭植物开发被表示,并且 subcellular 本地化试金证明那米饭 PSD 蛋白质在原子核和细胞质是在场的。在摘要,我们的数据暗示通常认为的 PSD 基因可能为正常米饭开发是不可缺少的,它的函数可能与 Arabidopsis PSD 的一样。 | Chengguo Yao Liangfa Ge Wei Li Botao Zhao Chaoqun Li Kangcheng Ruan Hongxuan Lin Youxin Jin | 2008 | Acta Biochimica et Biophysica Sinica2008，40，10： | 1 |
| 18 | Identity-based proxy signature scheme secure in standard model 显示文摘 | LI Mingxiang HAN Botao ZHU Jianyong | 2009 | Journal of South China University of Technology (Natural Science Edition )2009，129，： | 1 |
| 19 | Influence of Human Activities on Wintertime Haze-Related Meteorological Conditions over the Jing–Jin–Ji Region显示文摘This work analyzes and discusses the influence of human activities on the meteorological conditions related to winter haze events in Beijing,Tianjin,and Hebei(i.e.,the Jing-Jin-Ji region)during 1961-2016,using the results of two numerical simulation experiments based on the Community Atmosphere Model version 5.1.1(http://gffzza08704819dc54d8bhwxb66oc955ov6fun.ffgz.tsg.suse.edu.cn/models/cesm1.0/cam/docs/ug5_1_1/book1.html)used in the international Climate Variability and Predictability Programme(CLIVAR)Climate of the 20th Century Detection and Attribution Project(C20C+D&A).The results show that,under the influence of human activities,the changes in dynamical and thermal meteorological conditions related to winter haze events in the Jing–Jin–Ji region are conducive to the formation and accumulation of haze,and prevent the diffusion of pollutants.The dynamical conditions mainly include the obvious weakening of the East Asian winter monsoon(EAWM)and the enhancement of the near-surface anomalous southerly wind.The thermal conditions include the obvious increase in surface temperature,and the enhancement of water vapor transport and near-surface inversion.The relative contribution of dynamical and thermal conditions to the variation of haze days in the Jing-Jin-Ji region is analyzed using statistical methods.The results show that the contribution of human activities to the increase of haze days in the Jing-Jin-Ji region is greater than that of natural forcing for the study period.To be specific,the dynamical meteorological factors contribute more to the haze days than the thermal meteorological factors.The contribution of thermal meteorological factors is basically the same in both scenarios. | Ying Xu Yanju Liu Zhenyu Han Botao Zhou Yihui Ding Jie Wuc Tongfei Tian Rouke Li Jing Wang | 2021 | Engineering2021，7，8： | 1 |
| 20 | Antioxidant capacities andtotal phenolic contents of 62 fruits显示文摘 | FU Li XU Botao XU Xiangrong | 2011 | Food Chemistry2011，129，2： | 1 |
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