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| 1 | Effect of Root Architecture on Structural Stability and Erodibility of Topsoils during Concentrated Flow in Hilly Loess Plateau显示文摘Traditional vegetation techniques for the control of concentrated flow erosion are widely recognized, whereas only a few studies have experimentally investigated the impacts of belowground roots on the erodibility of topsoils in semi-arid areas. To quantify the effects of root architectures on soil erodibility and its relevant structural properties, simulated flow experiments were conducted at six-week intervals from 18 July to 20 October in 2012 in the hilly Loess Plateau. Five treatments were: 1) bare(control), 2) purple alfalfa(Medicago sativa), representing tap roots(T), 3) switchgrass(Panicum virgatum), representing fibrous roots(F), 4) purple alfalfa and switchgrass, representing both tap and fibrous roots(T + F), and 5) natural recovery(N). For each treatment, soil structural properties and root characteristics were measured at an interval of six weeks. Soil anti-scouribility was calculated. Results showed that grass planting slightly reduced soil bulk density, but increased soil aggregate content by 19.1%, 10.6%, 28.5%, and 41.2% in the treatments T, F, T + F, and N, respectively. Soil shear strength(cohesion and angle of internal friction(φ)) significantly increased after the grass was planted. As roots grew, soil cohesion increased by 115.2%–135.5%, while soil disintegration rate decreased by 39.0%–58.1% in the 21 th week compared with the recorded value in the 9th week. Meanwhile, root density and root surface area density increased by 64.0%–104.7% and 75.9%–157.1%, respectively. No significant differences in soil anti-scouribility were observed between the treatments of T and F or of T + F and N, but the treatments of T + F and N performed more effectively than T or F treatment alone in retarding concentrated flow. Soil aggregation and root surface-area density explained the observed soil anti-scouribility during concentrated flow well for the different treatments. This result proved that the restoration of natural vegetation might be the most appropriate strategy in soil reinforcement in the hilly Loess Plateau. | LI Qiang LIU Guobin ZHANG Zheng TUO Dengfeng XU Mingxiang | 2015 | Chinese Geographical Science2015，25，6： | 13 |
| 2 | Physico-Chemical Properties and Laboratory Hyperspectral Reflectance of Coastal Saline Soil in Shangyu City of Zhejiang Province, China显示文摘45 and 50 composite soil samples were collected, respectively, from two agricultural fields, that were enclosed and reclaimed from coastal tidal-fiat areas in 1996 and 1984 respectively, in Shemgyu of Zhejiang Province, China, to investigate the physico-chemical properties and the hyperspectral characteristics of the saline soils and to make an assessment on their relationships. The reflectance spectra of saline soils were measured using a spectroradiometer in laboratory. The mean spectral curves of the saline soils from the two sites different in reclamation year showed that the saline soil taken from the recently reclaimed land with higher salinity demonstrated a lower reflectance intensity in the spectral region from about 550 nm to 2300 nm. In addition, nine absorption bands, i.e., 488 nm, 530 nm, 670 nm, 880 nm, 940 nm, 1400 nm,1900 nm, 2 200 nm and 2 300 nm, were chosen as the spectral bands to investigate the relationships between soil physico-chemical properties by means of Pearson correlation analysis. Finally, the first two principal components were calculated from nine absorption bands and used to discriminate the saline soil samples taken from two sampled fields. The results indicate that it is feasible to detect physico-chemical properties of saline soils from fields reclaimed for varying time periods on the basis of the hyperspectral data. | SHI ZHOU, HUANG MINGXIANG and LI YANInstitute of Agricultural Remote Sensing and Information System, Zhejiang University, Hangzhou 310029 (China) | 2003 | Pedosphere2003，13，3： | 12 |
| 3 | Effects of grain size on phase transition behavior of nanocrystalline shape memory alloys显示文摘We report recent advances in the experimental and theoretical study of grain size(GS)effects on the thermal and mechanical properties of nanostructured NiTi polycrystalline shape memory alloy(SMA).It is shown that when GS<60 nm,the superelastic stress-strain hysteresis loop area(H)of the polycrystal decreases rapidly with GS and tends to vanish as GS approaches 10 nanometers.At the same time,the temperature dependence of the transition stress also decreases with GS and eventually approaches zero,leading to a wide superelastic temperature window and breakdown of the Clausius-Claperyon relationship.Rate dependence of the stress-strain responses is significantly reduced and the cyclic stability of the material is improved by the nanocrystallization.It is proposed that the emergence of such significant changes in the behavior of the material with GS reduction originate from the large increase in the area-to-volume ratios of the nanometer-thick interfaces(grain boundary and Austenite-Martensite(A-M)interface)in the polycrystal.In particular,with GS reduction,interfacial energy terms will gradually become dominant over the bulk energy of the crystallite,eventually bring fundamental changes in the phase transition responses of the material.Modelling strategy leading to the establishment of quantitative relationships among GS,grain boundary,A-M interfaces and the macroscopic responses of the material are outlined. | SUN QingPing ASLAN Ahadi LI MingPeng CHEN MingXiang | 2014 | Science China(Technological Sciences)2014，57，4： | 9 |
| 4 | 3-year Treatment of Tenofovir Alafenamide vs.Tenofovir Disoproxil Fumarate for Chronic HBV Infection in China显示文摘Background and Aims:Tenofovir alafenamide(TAF)has similar efficacy to tenofovir disoproxil fumarate(TDF)but with improved renal and bone safety in chronic hepatitis B patients studied outside of China.We report 3-year results from two phase 3 studies with TAF in China(Clinicaltrials.gov:NCT02836249 and NCT02836236).Methods:Chinese hepatitis B e antigen(HBeAg)-positive and-negative chronic hepatitis B patients with viremia and elevated alanine aminotransferase were randomized 2:1 to TAF or TDF treatment groups and treated in a double-blind fashion for 144 weeks(3 years).Efficacy responses were assessed by individual study while safety was assessed by a pooled analysis.Results:Of the 334 patients(180 HBeAg-positive and 154 HBeAg-negative)randomized and treated,baseline characteristics were similar between groups.The overall mean age was 38 years and 73%were male.The mean HBV DNA was 6.4 log10 IU/mL.The median alanine aminotransferase was 88 U/L,and 37%had a history of antiviral use.At week 144,the proportion with HBV DNA<29 IU/mL was similar among the two groups,with TAF at 83%vs.TDF at 79%,and TAF at 93%vs.TDF at 92%for the HBeAg-positive and-negative patients,respectively.In each study,higher proportions of TAF than TDF patients showed normalized alanine aminotransferase(via the American Association for the Study of Liver Diseases and the China criteria)and showed loss of HBsAg;meanwhile,the HBeAg seroconversion rates were similar.Treatment was well-tolerated among the TAF patients,who showed a smaller median decline in creatinine clearance(−0.4 vs.−3.2 mL/min;p=0.014)and less percentage change in bone mineral density vs.TDF at hip(−0.95%vs.−1.93%)and spine(+0.35%vs.−1.40%).Conclusions:In chronic hepatitis B patients from China,TAF treatment provided efficacy similar to TDF but with better renal and bone safety at 3 years. | Jinlin Hou Qin Ning Zhongping Duan You Chen Qing Xie Fu-Sheng Wang Lunli Zhang Shanming Wu Hong Tang Jun Li Feng Lin Yongfeng Yang Guozhong Gong John FFlaherty Anuj Gaggar Shuyuan Mo Cong Cheng Gregory Camus Chengwei Chen Yan Huang Jidong Jia Mingxiang Zhang GS-US-320-0110 and GS-US-320-0108 China Investigators | 2021 | Journal of Clinical and Translational Hepatology2021，9，3： | 7 |
| 5 | esveratrol inhibits necroptosis by mediating the TNF-α/RIP1/RIP3/MLKL pathway in myocardial hypoxia/reoxygenation injury显示文摘Resveratrol(RES)protects myocardial cells from hypoxia/reoxygenation(H/R)-caused injury.However,the mechanism of this effect has not been clarified.Thus,in this study,we aimed to determine whether RES attenuates H/R-induced cell necroptosis by inhibiting the tumor necrosis factor-alpha(TNF-α)/receptor-interacting protein kinase 1(RIP1)/RIP3/mixed-lineage kinase domain-like(MLKL)signaling pathway.Rat myocardial ischemia/reperfusion(I/R)models and H/R-injured cell models were constructed.Our study showed that myocardial H/R injury significantly increased the levels of TNF-α,RIP1,RIP3,and p-MLKL/MLKL by western blot analysis.Cell viability assay and 4,6-dianmidino-2-phenylindole(DAPI)-propidium iodide staining showed that the cell viability was decreased,and necroptosis was increased after myocardial H/R injury.The expressions of TNF-α,RIP1,RIP3,and p-MLKL/MLKL in H/R myocardial cells treated with different concentrations of RES were significantly downregulated.In addition,we also found that the cell viability was increased and necroptosis was decreased in dose-dependent manners when H/R-injured cells were treated with RES.In addition,the enhanced effect of TNF-αon necroptosis in myocardial H/R-injured cells was improved by RES,and the effect of RES was confirmed in vivo in I/R rats.This study also showed that RES suppresses necroptosis in H9c2 cells,which may occur through the inhibition of the TNF-α/RIP1/RIP3/MLKL signaling pathway.Our data suggest that necroptosis is a promising therapeutic target and may be a promising therapeutic target for the treatment of myocardial I/R injury. | Yongjun Hu Hongwei Pan Jianqiang Peng Jin He Mingxiang Tang Sulan Yan Jingjing Rong Junshan Li Zhaofen Zheng Haijun Wang Yanfu Liu Xin Zhong | 2021 | Acta Biochimica et Biophysica Sinica2021，53，4： | 6 |
| 6 | Materials Experiment on Tiangong-2 Space Laboratory显示文摘During the China's Tiangong-2(TG-2) flight mission, the experiments of 18 kinds of material samples were conducted in space by using a Multiple Materials Processing Furnace(MMPF) mounted in the orbital module of the TG-2 space laboratory. After the experiments of 12 kinds of samples of the first and second batches were completed successfully, astronauts packed and brought them back to the ground by ShenzhouII spacecraft. By studying processing and formation on semiconductor and optoelectronics materials, metal alloys and metastable materials, functional single-crystal, micro-and nano-composite materials encapsulated in sample ampoules both in space and on Earth, we expect to explore some physical and chemical processes and mechanism of the materials formation that are normally obscured and therefore are difficult to study quantitatively on the ground due to the gravity-induced convection, to obtain the processing and synthesis technology for preparing high quality materials, and lead to the improvement and development of materials processing techniques on Earth, and also develop the experiment device and comprehensive ability for materials experiment in microgravity environment. This report briefly introduces the main points of each research work and preliminary comparative analysis results of 12 samples carried out by scientists undertaking research task. | LI Xiangyang LU Ye MENG Xiangjian WANG Jianlu WANG Reng CHEN Lidong HUA Zile LI Xiaoya SHI Jianlin LIU Jinfeng XU Guisheng WEI Bingbo XIE Wenjun YIN Zhigang ZHANG Xingwang JIANG Hongxiang LI Hong LUO Xinghong ZHANG Haifeng ZHAO Jiuzhou WANG Binbin PAN Mingxiang | 2018 | 空间科学学报2018，38，5： | 4 |
| 7 | DS-CDMA system outer loop power control and improvement for multi-service显示文摘When a new user accesses the CDMA system, the load will change drastically, and therefore, the advanced outer loop power control (OLPC) technology has to be adopted to enrich the target signal interference ratio (SIR) and improve the system performance. The existing problems about DS-CDMA outer loop power control for multi-service are introduced and the power control theoretical model is analyzed. System simulation is adopted on how to obtain the theoretical performance and parameter optimization of the power control algorithm. The OLPC algorithm is improved and the performance comparisons between the old algorithm and the improved algorithm are given. The results show good performance of the improved OLPC algorithm and prove the validity of the improved method for multi-service. | Guan Mingxiang Guo Qing Li Xing | 2008 | Journal of Systems Engineering and Electronics2008，19，3： | 3 |
| 8 | Targeting the ubiquitination/deubiquitination process to regulate immune checkpoint pathways显示文摘The immune system initiates robust immune responses to defend against invading pathogens or tumor cells and protect the body from damage,thus acting as a fortress of the body.However,excessive responses cause detrimental effects,such as inflammation and autoimmune diseases.To balance the immune responses and maintain immune homeostasis,there are immune checkpoints to terminate overwhelmed immune responses.Pathogens and tumor cells can also exploit immune checkpoint pathways to suppress immune responses,thus escaping immune surveillance.As a consequence,therapeutic antibodies that target immune checkpoints have made great breakthroughs,in particular for cancer treatment.While the overall efficacy of immune checkpoint blockade(ICB)is unsatisfactory since only a small group of patients benefted from ICB treatment.Hence,there is a strong need to search for other targets that improve the efficacy of ICB.Ubiquitination is a highly conserved process which participates in numerous biological activities,including innate and adaptive immunity.A growing body of evidence emphasizes the importance of ubiquitination and its reverse process,deubiquitination,on the regulation of immune responses,providing the rational of simultaneous targeting of immune checkpoints and ubiquitination/deubiquitination pathways to enhance the therapeutic efficacy.Our review will summarize the latest findings of ubiquitination/deubiquitination pathways for anti-tumor immunity,and discuss therapeutic significance of targeting ubiquitination/deubiquitination pathways in the future of immunotherapy. | Jiaxin Liu Yicheng Cheng Ming Zheng Bingxiao Yuan Zimu Wang Xinying Li Jie Yin Mingxiang Ye Yong Song | 2021 | Signal Transduction and Targeted Therapy2021，6，2： | 3 |
| 9 | Glassy metallic plastics显示文摘This paper reports a class of bulk metallic glass including Ce-, LaCe-, CaLi-, Yb-, and Sr-based metallic glasses, which are regarded as glassy metallic plastics because they combine some unique properties of both plastics and metallic alloys. These glassy metallic plastics have very low glass transition temperature (Tg^25oC to 150oC) and low Young’s modulus (~20 GPa to 35 GPa). Similar to glassy plastics, these metallic plastics show excellent plastic-like deformability on macro-, micro- and even nano-scale in their supercooled liquid range and can be processed, such as elongated, compressed, bent, and imprinted at low temperatures, in hot water for instance. Under ambient conditions, they display such metallic properties as high thermal and electric conductivities and excellent mechanical properties and other unique properties. The metallic plastics have potential applications and are also a model system for studying issues in glass physics. | LI JianFu, WANG JunQiang, LIU XiaoFeng, ZHAO Kun, ZHANG Bo, BAI HaiYang, PAN MingXiang & WANG WeiHua Institute of Physics, Chinese Academy of Sciences, Beijing 100190, China | 2010 | Science China(Physics,Mechanics & Astronomy)2010，53，3： | 2 |
| 10 | Stability a-nalysis on delayed neural networks based on an improveddelay-partitioning approach显示文摘 | Li Tao Song Aiguo Xue Mingxiang | 2011 | Journal of Computationaland Applied Mathematics2011，235，： | 1 |
| 11 | Social network and social capital in leadership and management research:A review of causal method显示文摘 | MINGXIANG LI | 2013 | The Leadership Quarterly2013，24，： | 1 |
| 12 | Study on sequence stratigraphic framework and relative sea-level changes for the Devonian of the Qian-Gui area 显示文摘 | MEI Mingxiang GAO Jinhan LI Donghai | 2003 | Acta Sedimentologica Sinica2003，21，2： | 1 |
| 13 | Sedimentary Facies Architectures of Third-Order Sequences from Early to Middle Triassic in Nanpanjiang Basin显示文摘There are complex and regular changes on sedimentary facies from the Early to the Middle Triassic in the Nanpanjiang basin. After the obvious drowned event of carbonate platforms in the transitional period between Permian and Triassic, carbonate platforms have evolved into the ramp type from the rimmed shelf type. The differentiation of sedimentary facies becomes clearer in space, which are marked by the changes from an attached platform to a turbidity basin and several isolated platforms in the basin. The striking characteristics are the development of oolitic banks on isolated platforms in Nanning and Jingxi and the reef and bank limestones in the margin of the attached platform in the Early Triassic. Despite the difference of the time span and the architecture of facies succession of third order sedimentary sequences, the process of the third order relative sea level changes reflected by the sedimentary facies succession of the third order sequences is generally synchronous. Therefore, six third order sequences could be discerned in the strata from the Early to the Middle Triassic in the Nanpanjiang basin. Using two types of facies changing surfaces and two types of diachronisms in stratigraphic records as the key elements, the sedimentary facies architectures of the third order sequences that represent sequence stratigraphic frameworks from the Early to the Middle Triassic in the Nanpanjiang basin could be constructed. | Mei Mingxiang Ma Yongsheng Deng Jun Gao Jinhan Chen Huijun Meng Qingfen Li Donghai Faculty of Earth Sciences and Resources, China University of Geosciences, Beijing 100083 | 2003 | Journal of China University of Geosciences2003，14，2： | 1 |
| 14 | Identity-based proxy signature scheme secure in standard model 显示文摘 | LI Mingxiang HAN Botao ZHU Jianyong | 2009 | Journal of South China University of Technology (Natural Science Edition )2009，129，： | 1 |
| 15 | Association between porpoise presence and fish choruses:implications for feeding strategies and ecosystem-based conservation of the East Asian finless porpoise显示文摘The associations between feeding activities and environmental variables inform animal feeding tactics that max-imize energetic gains by minimizing energy costs while maximizing feeding success.Relevant studies in aquatic animals,particularly marine mammals,are scarce due to difficulties in the observation of feeding behaviors in aquatic environments.This data scarcity concurrently hinders ecosystem-basedfishery management in the context of small toothed-cetacean conservation.In the present study,a passive acoustic monitoring station was deployed in an East Asianfinless porpoise habitat in Laizhou Bay to investigate potential relationships between East Asianfinless porpoises and their prey.The data revealed that porpoises were acoustically present nearly every day during the survey period.Porpoise detection rates differed between spring and autumn in concert with activities offish choruses.During spring,fish choruses were present throughout the afternoon,and this was the time when porpoise vocalizations were the most frequently detected.During autumn,whenfish choruses were absent,porpoise detec-tion rates decreased,and diurnal patterns were not detected.The close association betweenfish choruses andfin-less porpoise activities implies an“eavesdropping”feeding strategy to maximize energetic gains,similar to other toothed cetaceans that are known to engage similar feeding strategies.Underwater noise pollution,particularly those maskingfish choruses,could interruptfinless porpoises’feeding success.Fisheries competing soniferousfishes withfinless porpoise could impactfinless porpoise viability through ecosystem disruption,in addition tofishing gear entanglement. | Zhaolong CHENG Yongtao LI Matthew Keith PINE Tao ZUO Mingxiang NIU Jun WANG | 2023 | Integrative Zoology2023，18，1： | 1 |
| 16 | Identification of an unknown extraneous contaminant in pharmaceutical product analysis显示文摘 | LIN Mingxiang LI Min RUSTUM A | 2007 | J Pharm Biomed Anal2007，45，5： | 1 |
| 17 | Role of asymmetric environment on the dark mode excitation in metamaterial analogue of electromagnetically-induced transparency 显示文摘 | DONC Zhenggao LIu Hui Xu Mingxiang LI Tao WANG Shuming CAO Jingxiao ZHU Shining ZHANG Xiang | 2010 | Optics Express2010，18，22： | 1 |
| 18 | Thoracoscopic Esophagectomy in Prone Versus Decubitus Position: Ergonomic Evaluation From a Randomized and Controlled Study显示文摘 | Yaxing Shen Mingxiang Feng Lijie Tan Hao Wang Jingpei Li Yong Xi Qun Wang | 2014 | The Annals of Thoracic Surgery2014，，： | 1 |
| 19 | A novel access protocol for communication system in near space显示文摘 | Guan Mingxiang Guo Qing Li Lu | 2007 | IEEE Journal on Selected Areas in Communications2007，22，： | 1 |
| 20 | Integrative Analysis of Genome,3D Genome,and Transcriptome Alterations of Clinical Lung Cancer Samples显示文摘Genomic studies of cancer cell alterations,such as mutations,copy number variations(CNVs),and translocations,greatly promote our understanding of the genesis and development of cancers.However,the 3D genome architecture of cancers remains less studied due to the complexity of cancer genomes and technical difficulties.To explore the 3D genome structure in clinical lung cancer,we performed Hi-C experiments using paired normal and tumor cells harvested from patients with lung cancer,combining with RNA sequenceing analysis.We demonstrated the feasibility of studying 3D genome of clinical lung cancer samples with a small number of cells(1×10^(4)),compared the genome architecture between clinical samples and cell lines of lung cancer,and identified conserved and changed spatial chromatin structures between normal and cancer samples.We also showed that Hi-C data can be used to infer CNVs and point mutations in cancer.By integrating those different types of cancer alterations,we showed significant associations between CNVs,3D genome,and gene expression.We propose that 3D genome mediates the effects of cancer genomic alterations on gene expression through altering regulatory chromatin structures.Our study highlights the importance of analyzing 3D genomes of clinical cancer samples in addition to cancer cell lines and provides an integrative genomic analysis pipeline for future larger-scale studies in lung cancer and other cancers. | Tingting Li Ruifeng Li Xuan Dong Lin Shi Miao Lin Ting Peng Pengze Wu Yuting Liu Xiaoting Li Xuheng He Xu Han Bin Kang Yinan Wang Zhiheng Liu Qing Chen Yue Shen Mingxiang Feng Xiangdong Wang Duojiao Wu Jian Wang Cheng Li | 2021 | Genomics, Proteomics & Bioinformatics2021，19，5： | 1 |
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