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| 1 | An Uncanonical CCCH-Tandem Zinc-Finger Protein Represses Secondary Wall Synthesis and Controls Mechanical Strength in Rice显示文摘第二等的墙,代表生物资源的体积,在植物生长和改编上有大影响到环境。第二等的墙合成被一个复杂发信号 transduction 网络交换并且调整。然而,有这些规章的小径的有限理解。这里,我们报导(IIP4 )交往 ILA1 蛋白质 4 能镇压第二等的墙合成。IIP4 是象 Raf 一样 MAPKKK 的 phosphorylation 底层,但是它的功能是未知的。由产生 iip4 异种和相关转基因的植物,我们发现在 IIP4 的损害提高第二等的墙形成。基因表示和 transactivation 活动试金表明 IIP4 否定地调整 MYB61 和 CESA 的表示但是不绑 ? 他们的倡导者。IIP4 与 NAC29/NAC31 交往,第二等的墙合成的在上游的管理者,并且在植物压制下游地规章的小径。显示出的 Mutagenesis 分析那 phosphomimic IIP4 从原子核的蛋白质 translocate 到细胞质。而且,我们表明 IIP evolutionarily 被保存并且分享 unreported CCCH 主题,叫作 uncanonical CCCH 双人脚踏车锌手指蛋白质。一起,我们的学习提供机械学的卓见进第二等的墙合成的控制并且为在庄稼改进相关农学的特点介绍一个机会。 | Dongmei Zhang Zuopeng Xu Shaoxue Cao Kunling Chen Shance Li Xiangling Liu Caixia Gao Baocai Zhang Yihua Zhou | 2018 | Molecular Plant2018，11，1： | 14 |
| 2 | Using a support vector machine method to predict the development indices of very high water cut oilfields显示文摘Because the oilfields in eastern China are in the very high water cut development stage, accurate forecast of oilfield development indices is important for exploiting the oilfields efficiently. Regarding the problems of the small number of samples collected for oilfield development indices, a new support vector regression prediction method for development indices is proposed in this paper. This method uses the principle of functional simulation to determine the input-output of a support vector machine prediction system based on historical oilfield development data. It chooses the kernel function of the support vector machine by analyzing time series characteristics of the development index; trains and tests the support vector machine network with historical data to construct the support vector regression prediction model of oilfield development indices; and predicts the development index. The case study shows that the proposed method is feasible, and predicted development indices agree well with the development performance of very high water cut oilfields. | Zhong Yihua Zhao Lei Liu Zhibin Xu Yao Li Rong | 2010 | Petroleum Science2010，7，3： | 11 |
| 3 | dentification of TRA2B-DNAH5 fusion as a novel oncogenic driver in human lung squamous cell carcinoma显示文摘 | Fei Li Zhaoyuan Fang Jian Zhang Chen Li Hongyan Liu Jufeng Xia Hongwen Zhu Chenchen auo Zhen Qin Fuming Li Xiangkun Han Yuetong Wang Yan Feng Ye Wang Wenjing Zhang Zuoyun Wang Yujuan Jin Yihua Sun Wenyi Wei Rong Zeng Haiquan Chen Hongbin Ji | 2016 | Cell Research2016，26，10： | 9 |
| 4 | 8-hydroxy-dipropylaminotetralin promotes neural plasticity in epileptic rats with depression显示文摘Rats with chronic pilocarpine-induced temporal lobe epilepsy complicated with depression were studied. Anti-5-bromodeoxyuridine immunofluorescence staining and Timms staining showed that neurogenesis within the hippocampal dentate gyrus and mossy fiber sprouting were increased in model rats. Neurogenesis within the hippocampal dentate gyrus was further enhanced, while mossy fiber sprouting was decreased in model rats administered carbamazepine alone or in combination with the 5-hydroxytryptamine 1A receptor agonist, 8-hydroxy-dipropylaminotetralin (0.1 and 1 mg/kg). Among the groups, the effect was the most significant in rats receiving carbamazepine in conjunction with 1 mg/kg 8-hydroxy-dipropylaminotetralin. Thus, high dose 8-hydroxy-dipropylaminotetralin can improve neural plasticity in epileptic rats with depression. | Ping Yang Meizhen Sun Liang Li Yihua Shen | 2012 | Neural Regeneration Research2012，7，8： | 7 |
| 5 | Neomycin biosynthesis is regulated positively by AfsA-g and NeoR in Streptomyces fradiae CGMCC 4.7387显示文摘Neomycins are a group of aminoglycoside antibiotics with both clinical and agricultural applications.To elucidate the regulatory mechanism of neomycin biosynthesis,we completed draft genome sequencing of a neomycin producer Streptomyces fradiae CGMCC 4.7387 from marine sediments,and the neomycin biosynthesis gene cluster was identified.Inactivation of the afsA-g gene encoding a γ-butyrolactone(GBL) synthase in S.fradiae CGMCC 4.7387 resulted in a significant decrease of neomycin production.Quantitative RT-PCR analysis revealed that the transcriptional level of neoR and the aphA-neoGH operon were reduced in the afsA-g::aac(3)Ⅳ mutant.Interestingly,a conserved binding site of AdpA,a key activator in the GBL regulatory cascade,was discovered upstream of neoR,a putative regulatory gene encoding a protein with an ATPase domain and a tetratricopeptide repeat domain.When neoR was inactivated,the neomycin production was reduced about 40%in comparison with the WT strain.Quantitative RT-PCR analysis revealed that the transcriptional levels of genes in the aphA-neoGH operon were reduced clearly in the neoR::aac(3)Ⅳ mutant.Finally,the titers of neomycin were improved considerably by overexpression of qfsA-gand neoR in S.fradiae CGMCC 4.7387. | Xiangxi Meng Wenzhao Wang Zhoujie Xie Pengwei Li Yue Li Zhengyan Guo Yingjian Lu Jie Yang Kaile Guan Zhaoxin Lu Huarong Tan Yihua Chen | 2017 | Science China(Life Sciences)2017，60，9： | 7 |
| 6 | Pleniglacial millennium-scale climate variations in northern China based on records from the Salawusu River Valley显示文摘Situated in the Salawusu River Valley, southeast of China's Mu Us Desert, the MGS2 (Milanggouwan section) portion of the Milanggouwan stratigraphic section records 5.5 sedimentary cycles consisting of alternations between dune sand deposits and fluvial or lacustrine facies. We analyzed the grain-size and CaCO 3 distributions in MGS2, and found that Mz (mean particle diameter) and σ (standard deviation) displayed clear variations in peaks and valleys within different sedimentary facies. The CaCO 3 content averaged 0.4% in the dune sand deposits, 1.43% in the fluvial facies, and 8.82% in the lacustrine facies. Both the grain-size distribution and CaCO 3 contents, which equal the indicators for the alternation among the sedimentary facies, suggest the occurrence of 5.5 cycles. These results suggest that the observed cycles mainly resulted from fluctuations between a cold and dry winter monsoon climate and a warm and humid summer monsoon climate, and that the MGS2 portion experienced at least 5.5 fluctuations between these two extremes. This high-frequency climatic fluctuation indicates a strong influence of millennium-scale variations in the strength of the East Asian winter and summer monsoons in our study area during the Pleniglacial. | FengNian WANG BaoSheng LI JiangLong WANG XiaoHao WEN DongFeng NIU ZhiWen LI YueJun SI YiHua GUO ShuHuan DU | 2012 | Journal of Arid Land2012，4，3： | 7 |
| 7 | NON-YELLOWING2 (NYE2), a Close Paralog of NYE1, Plays a Positive Role in Chlorophyll Degradation in Arabidopsis显示文摘 | Wu, Shouxin Li, Zhongpeng Yang, Lifeng Xie, Zuokun Chen, Junyi Zhang, Wei Liu, Tianqi Gao, Shan Gao, Jiong Zhu, Yihua Xin, Jiwen Ren, Guodong Kuai, Benke | 2016 | Molecular Plant2016，9，4： | 6 |
| 8 | Genetic analysis and preimplantation genetic diagnosis of Chinese Marfan syndrome patients显示文摘Marfan syndrome (MFS)(OMIM 154700) is a relatively common autosomal dominant genetic disease that causes skeletal, ocular, and cardiovascular defects and was first described by a French pediatrician in 1896 (Bitterman and Sponseller, 2017). Its prevalence rate is 1/3000—1/5000, and more than 25% of cases are sporadic (Chiu et al., 2014). Studies have shown that about 90% of MFS is caused by variants in the fibrillin-1 gene (FBN1, OMIM 134797). FBN1, located on chromosome 15q21.1, encodes a macromolecular glycoprotein-fibrin 1, which aggregates to form microfibers in the extracellular matrix and distributes in various human connective tissues, such as periosteum, vessel wall, and crystal suspensor ligament. Variants in FNB1 have been reported in 65 exons, but the relationship between genotype and phenotype remains rather unclear (Sakai et al., 2016). Studies have also shown that patients with MFS and similar diseases may have variants in other related genes such as members of the transforming growth factor beta receptor (TGFBR) family (Mizuguchi et al., 2004;Sakai et al., 2006;Bolar et al., 2012;De Cario et al., 2018). For better prevention and treatment of MFS as well as for suspected MFS patients, there is a strong need for efficient genetic testing for early diagnosis and differential diagnoses of patients with related phenotypes (Aubart et al., 2018). | Meng Qin Xiaohui Zhu Zhe Zhang Xuemin Li Zhiqiang Yan Yuqian Wang Shuo Guan Yihua He Wenxin Zhang Liying Yan Jie Qiao Xu Zhi | 2019 | Journal of Genetics and Genomics2019，46，6： | 6 |
| 9 | Quantum network communication: a discrete-time quantum-walk approach显示文摘We study the problem of quantum multi-unicast communication over the butterfly network in a quantum-walk architecture, where multiple arbitrary single-qubit states are transmitted simultaneously between multiple source-sink pairs. Here, by introducing quantum walks, we demonstrate a quantum multiunicast communication scheme over the butterfly network and the inverted crown network, respectively,where the arbitrary single-qubit states can be efficiently transferred with both the probability and the state fidelity one. The presented result concerns only the butterfly network and the inverted crown network, but our techniques can be applied to a more general graph. It paves a way to combine quantum computation and quantum network communication. | Yuguang YANG Jiajie YANG Yihua ZHOU Weimin SHI Xiubo CHEN Jian LI Huijuan ZUO | 2018 | Science China(Information Sciences)2018，61，4： | 5 |
| 10 | RIP1-dependent linear and nonlinear recruitments of caspase-8 and RIP3 respectively to necrosome specify distinct cell death outcomes显示文摘There remains a significant gap in our quantitative understanding of crosstalk between apoptosis and necroptosis pathways.By employing the SWATH-MS technique,we quantified absolute amounts of up to thousands of proteins in dynamic assembling/de-assembling of TNF signaling complexes.Combining SWATH-MS-based network modeling and experimental validation,we found that when RIP1 level is below~1000 molecules/cell(mpc),the cell solely undergoes TRADD-dependent apoptosis.When RIP1 is above~1000 mpc,pro-caspase-8 and RIP3 are recruited to necrosome respectively with linear and nonlinear dependence on RIP1 amount,which well explains the co-occurrence of apoptosis and necroptosis and the paradoxical obser-vations that RIP1 is required for necroptosis but its increase down-regulates necroptosis.Higher amount of RIP1(>~46,000 mpc)suppresses apoptosis,leading to necroptosis alone.The relation between RIP1 level and occurrence of necroptosis or total cell death is biphasic.Our study provides a resource for encoding the com-plexity of TNF signaling and a quantitative picture how distinct dynamic interplay among proteins function as basis sets in signaling complexes,enabling RIP1 to play diverse roles in governing cell fate decisions. | Xiang Li Chuan-Qi Zhong Rui Wu Xiaozheng Xu Zhang-Hua Yang Shaowei Cai Xiurong Wu Xin Chen Zhiyong Yin Qingzu He Dianjie Li Fei Xu Yihua Yan Hong Qi Changchuan Xie Jianwei Shuai Jiahuai Han | 2021 | Protein & Cell2021，12，11： | 5 |
| 11 | The novel gene BrMYB2,located on chromosome A07,with a short intron 1 controls the purple-head trait of Chinese cabbage(Brassica rapa L.)显示文摘Anthocyanins are important secondary metabolites in plants,but information on anthocyanin biosynthesis mechanisms in Chinese cabbage is limited.The new purple head Chinese cabbage cultivar 11S91 was analyzed,and an R2R3-MYB regulatory gene BrMYB2,located on chromosome A07,controlling the dominant purple-head trait was isolated.High expression of BrMYB2 generated a large accumulation of anthocyanins in 11S91,accompanied by highly upregulated BrTT8,BrF3′H,BrDFR1,BrANS1,BrUGTs,BrATs,and BrGSTs.11S91 inherited the purple locus from purple trait donor 95T2-5,and they shared consensus CDSs and gDNAs with those of BrMYB2(cBrMYB2 and gBrMYB2).Two SNPs in cBrMYB2 in 11S91 did not cause loss of function;in addition to several SNPs at both ends of intron 1,a large deletion had occurred in intron 1 of gBrMYB2 in 11S91.Genetic transformation of Arabidopsis showed that gBrMYB2 overexpression lines presented deeper purple color and higher expression than did the cBrMYB2 and cBrmyb2 lines,whereas gBrmyb2 with a long intron 1 did not cause the purple phenotype.We first show that BrMYB2 promotes anthocyanin biosynthesis under the control of the short intron 1 of gBrMYB2 in purple head Chinese cabbage,and gBrmyb2 with a long intron 1 represses anthocyanin production in white head Chinese cabbage.This evidence provides a new understanding of anthocyanin biosynthesis and purple germplasm generation in Brassica vegetables. | Qiong He Junqing Wu Yihua Xue Wenbin Zhao Ru Li Lugang Zhang | 2020 | Horticulture Research2020，7，1： | 4 |
| 12 | Frog community responses to recent American bullfrog invasions显示文摘 | Yiming LI Zhunwei KE Yihua WANG Tim M. BLACKBURN | 2011 | Current Zoology2011，57，1： | 4 |
| 13 | Infection and Colonization of Pathogenic Fungus Fusarium proliferatum in Rice Spikelet Rot Disease显示文摘Rice spikelet rot disease(RSRD), caused by Fusarium proliferatum, is an emerging disease. So far, the effects of diseased rice floral organs as well as the primary infection sites and stages of this pathogen are not determined. We investigated changes in the floral organs, along with the infection processes of the pathogen in plants inoculated with F. proliferatum and labelled with a green fluorescent protein during different growth stages of rice. The results showed that RSRD is not a systemic infectious disease, which has negative effects on the fertility of the infected rice. F. proliferatum caused brown colored anthers, crinkled pistils and ovaries, pollen grain deformities and anther indehiscence. The number of pollen grains on the stigmas decreased significantly in the infected spikelets, and the anther dehiscence and seed-setting rate successively declined by 69% and 73%, respectively, as a result of the infection. The initial infection stage occurred at the pollen cell maturity stage, and the primary invasion sites were determined to be the anthers of rice. It was noted that the pathogen mainly damaged the pollen cells, and with the exception of the filaments, proceeded to colonize the pistils and endosperm. | SUN Lei WANG Ling LIU Lianmeng HOU Yuxuan XU Yihua LIANG Mengqi GAO Jian LI Qiqin HUANG Shiwen | 2019 | Rice science2019，26，1： | 3 |
| 14 | Growth and photosynthesis responses of Phaeodactylum tricornutum to dissolved organic matter from salt marsh plant and sediment显示文摘The effects of allochthonous dissolved organic matter (DOM) on the growth and photosynthesis of Phaeodactylum tricornutum were investigated. P. tricornutum incubated in f/2 medium was exposed to DOM additives, which were extracted from the plant and sediment samples of a salt marsh in North Branch of the Yangtze estuary, China. During 12 days incubation, the chlorophyll fluorescence parameters of P. tricornutum were measured by a Phyto-PAM phytoplankton analyzer. Spectral properties of DOM in algae filtrates were also observed. The concentrations of chlorophyll a, active chlorophyll a, and the maximum quantum yield of photosystem II significantly decreased after four days of incubation, suggesting that the growth and photosynthetic efficiency of P. tricornutum were inhibited. After adding sediment-DOM extract, both a 250 /a 365 (the ratio of the absorption coefficients at 250 and 365 nm) and S values (spectral slope coefficients) of algae filtrates declined in the first two days, which demonstrated a loss of low molecular weight DOM. Parallel factor analysis of fluorescence spectra of DOM in algae filtrates revealed that DOM could be classified into two humic-like and two protein-like components. The fluorescence intensity of tyrosine-like component originating from algae increased significantly during incubation. This study supports the hypothesis that allochthonous DOM derived from salt marsh plant and sediment have a strong influence on the adjacent aquatic ecosystems. | Yihua Xiao Qinghui Huang Ling Chen Penghui Li | 2010 | Journal of Environmental Sciences2010，22，8： | 3 |
| 15 | Mining of a streptothricin gene cluster from Streptomyces sp.TP-A0356 genome via heterologous expression显示文摘Streptothricins (STs) are used commercially to treat bacterial and fungal diseases in agriculture. Mining of the sequenced microbial genomes uncovered two cryptic ST clusters from Streptomyces sp. C and Streptomyces sp. TP-A0356. The ST cluster from S. sp. TP-A0356 was verified by successful heterologous expression in Streptomyces coelicolor M145. Two new ST analogs were produced together with streptothricin F and streptothricin D in the heterologous host. The ST cluster was further confirmed by inactivation of gene stnO, which was proposed encoding an aminomutase supplying -lysines for the poly-β-Lys chain formation. A putative biosynthetic pathway for STs is proposed based on bioinformatics analyses of the ST genes and experimental evidence. | LI JinE GUO ZhengYan HUANG Wei MENG XiangXi AI GuoMin TANG GongLi CHEN YiHua | 2013 | Science China(Life Sciences)2013，56，7： | 3 |
| 16 | An Android Malware Detection System Based on Feature Fusion显示文摘In order to improve the detection efficiency of Android malicious application, an Android malware detection system based on feature fusion is proposed on three levels. Feature fusion especially emphasizes on ten categories, which combines static and dynamic features and includes 377 features for classification. In order to improve the accuracy of malware detection, attribute subset selection and principle component analysis are used to reduce the dimensionality of fusion features. Random forest is used for classification. In the experiment, the dataset includes 43,822 benign applications and 8,454 malicious applications. The method can achieve 99.4% detection accuracy and 0.6% false positive rate. The experimental results show that the detection method can improve the malware detection efficiency in Android platform. | LI Jian WANG Zheng WANG Tao TANG Jinghao YANG Yuguang ZHOU Yihua | 2018 | Chinese Journal of Electronics2018，27，6： | 3 |
| 17 | Rice seed identification by computerized AFLP-DNA fingerprinting显示文摘Wedevelopedacomputerizedseedidentificationsystem.FifteenricevarietiesthatwerewidelyusedinChinawereanalyzedbyAFLPfingerprinting.12primerpairswerescreened.Inordertosimplifytheprocedureandcutdownthecostinseedidentification,theleastnumberofprimerpairsforpracticalseedidentifi cationshouldbeselected. | CHEN Yihua JIA Jianhang LI Chuanyou WANG Bin WENG Manli Inst of Genetics,Chinese Academy of Sci,Beijing 100101,China | 2000 | Chinese Rice Research Newsletter2000，8，1： | 2 |
| 18 | Construction of single-chromosome DNA library from Lilium regale Wilson显示文摘A protocol of simple rapid microdissection of single-chromosome, amplification and cloning of its DNA from Lilium regale Wilson is described. Single-chromosome, microdissected by micromanipulator, was put into a 0 5 mL Eppendorf tube and digested with Sau3A, and then the Sau3A linker adaptors were ligated to the ends of DNA fragments. After 2 rounds of PCR amplification with one chain of linker adaptor as primer, the PCR products thus obtained have a length of 300-2 500 base pairs (bp) with predominant fragments at about 1 000 bp. Southern blot analysis confirmed that the PCR products originated from the genome of Lilium regale Wilson. By cloning the amplification products from the second round of PCR, single-chromosome DNA library was constructed, in which about as many as 100 000 recombinant clones were produced. A total number of 84 clones were analysed, and it was revealed that the inserts ranged in size from 300 to 1 800 bp, with an average of 780 bp. Compared with the methods described in other literature, this protocol, eliminating the need for enzymatic digestion and ligating micromanipulation of chromosomal DNA in nanoliter volumes, permits the efficient amplification of single chromosome (not tens of chromosomes as reported before) and the fragments (780 bp in average) cloned in this study are longer than those reported before (650 bp in average). | Benyuan Dang Zanmin Hu Yihua Zhou Lihua Cui Lanlan Wang Liangcai Li Zhenghua Chen | 1998 | Chinese Science Bulletin1998，43，5： | 2 |
| 19 | Magnetic Flux Leakage Course of Inner Defects and Its Detectable Depth显示文摘As a promising non-destructive testing(NDT)method,magnetic flux leakage(MFL)testing has been widely used for steel structure inspection.However,MFL testing still faces a great challenge to detect inner defects.Existing MFL course researches mainly focus on surface-breaking defects while that of inner defects is overlooked.In the paper,MFL course of inner defects is investigated by building magnetic circuit models,performing numerical simulations,and conducting MFL experiments.It is found that the near-surface wall has an enhancing effect on the MFL course due to higher permeability of steel than that of air.Further,a high-sensitivity MFL testing method consisting of Helmholtz coil magnetization and induction coil with a high permeability core is proposed to increase the detectable depth of inner defects.Experimental results show that inner defects with buried depth up to 80.0 mm can be detected,suggesting that the proposed MFL method has the potential to detect deeply-buried defects and has a promising future in the field of NDT. | Jianbo Wu Wenqiang Wu Erlong Li Yihua Kang | 2021 | Chinese Journal of Mechanical Engineering2021，34，4： | 2 |
| 20 | Lymphangiogenesis contributes to exercise-induced physiological cardiac growth显示文摘Background:Promoting cardiac lymphangiogenesis exerts beneficial effects for the heart.Exercise can induce physiological cardiac growth with cardiomyocyte hypertrophy and increased proliferation markers in cardiomyocytes.However,it remains unclear whether and how lymphangiogenesis contributes to exercise-induced physiological cardiac growth.We aimed to investigate the role and mechanism of lymphangiogenesis in exercise-induced physiological cardiac growth.Methods:Adult C57 BL6/J mice were subjected to 3 weeks of swimming exercise to induce physiological cardiac growth.Oral treatment with vascular endothelial growth factor receptor 3(VEGFR3) inhibitor SAR1 3 1 675 was used to investigate whether cardiac lymphangiogenesis was required for exercise-induced physiological cardiac growth by VEGFR3 activation.Furthermore,human dermal lymphatic endothelial cell(LEC)-conditioned medium was collected to culture isolated neonatal rat cardiomyocytes to determine whether and how LECs could influence cardiomyocyte proliferation and hypertrophy.Results:Swimming exercise induced physiological cardiac growth accompanied by a remarkable increase of cardiac lymphangiogenesis as evidenced by increased density of lymphatic vessel endothelial hyaluronic acid receptor 1-positive lymphatic vessels in the heart and upregulated LYVE-1 and Podoplanin expressions levels.VEGFR3 was upregulated in the exercised heart,while VEGFR3 inhibitor SAR131675 attenuated exercise-induced physiological cardiac growth as evidenced by blunted myocardial hypertrophy and reduced proliferation marker Ki67 in cardiomyocytes,which was correlated with reduced lymphatic vessel density and downregulated LYVE-1 and Podoplanin in the heart upon exercise.Furthermore,LEC-conditioned medium promoted both hypertrophy and proliferation of cardiomyocytes and contained higher levels of insulinlike growth factor-1 and the extracellular protein Reelin,while LEC-conditioned medium from LECs treated with SAR131675 blocked these effects.Functional rescue assays further demonstrated that protein kinase B(AKT) activation,as well as reduced CCAAT enhancer-binding protein beta(C/EBPβ) and increased CBP/p300-interacting transactivators with E(glutamic acid)/D(aspartic acid)-rich-carboxylterminal domain 4(CITED4),contributed to the promotive effect of LEC-conditioned medium on cardiomyocyte hypertrophy and proliferation.Conclusion:Our findings reveal that cardiac lymphangiogenesis is required for exercise-induced physiological cardiac growth by VEGFR3 activation,and they indicate that LEC-conditioned medium promotes both physiological hypertrophy and proliferation of cardiomyocytes through AKT activation and the C/EBPβ-CITED4 axis.These results highlight the essential roles of cardiac lymphangiogenesis in exercise-induced physiological cardiac growth. | Yihua Bei Zhenzhen Huang Xing Feng Lin Li Meng Wei Yujiao Zhu Shuqin Liu Chen Chen Mingming Yin Huimin Jiang Junjie Xiao | 2022 | Journal of Sport and Health Science2022，11，4： | 2 |
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