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| 1 | VGLL4 functions as a new tumor suppressor in lung cancer by negatively regulating the YAP-TEAD transcriptional complex显示文摘肺癌症是与高发生和死亡世界范围的大多数破坏疾病之一。河马(Hpo ) 小径是在果蝇和哺乳动物的机关尺寸的一个保存管理者。新兴的证据在癌症开发建议了 Hpo 小径的意义。在这研究,我们通过否定地调整 YAP-TEAD 建筑群的形成在肺 carcinogenesis 作为新奇肿瘤 suppressor 识别 VGLL4, Hpo 的核心部件小径。我们 VGLL4 经常被观察低层的数据表演在老鼠和人的肺癌症标本表示了。VGLL4 的宫外的表示显著地在 vitro 压制肺癌症房间的生长。更重要地, VGLL4 显著地在 de novo 老鼠模型禁止肺癌症前进。我们进一步发现 VGLL4 禁止 YAP-TEAD transcriptional 建筑群的活动。我们 VGLL4 直接在绑定与笨蛋竞争到 TEAD 并且执行的数据表演它通过二 TDU 域的生长禁止的函数。一起,我们的学习证明 VGLL4 是为通过否定地调整 YAP-TEAD 复杂形成并且这样的肺癌症的新奇肿瘤 suppressor Hpo 小径。 | Wenjing Zhang Yijun Gao Peixue Li Zhubing Shi Tong Guo Fei Li Xiangkun Han Yan Feng Chao Zheng Zuoyun Wang Fuming Li Haiquan Chen Zhaocai Zhou Lei Zhang Hongbin Ji | 2014 | Cell Research2014,24,3: | 25 |
| 2 | Identification of RET gene fusion by exon array analyses in "pan-negative" lung cancer from never smokers显示文摘 | Li, Fei Feng, Yan Fang, Rong Fang, Zhaoyuan Xia, Jufeng Han, Xiangkun Liu, Xin-Yuan Chen, Haiquan Liu, Hongyan Ji, Hongbin | 2012 | Cell Research2012,22,5: | 11 |
| 3 | dentification of TRA2B-DNAH5 fusion as a novel oncogenic driver in human lung squamous cell carcinoma显示文摘 | Fei Li Zhaoyuan Fang Jian Zhang Chen Li Hongyan Liu Jufeng Xia Hongwen Zhu Chenchen auo Zhen Qin Fuming Li Xiangkun Han Yuetong Wang Yan Feng Ye Wang Wenjing Zhang Zuoyun Wang Yujuan Jin Yihua Sun Wenyi Wei Rong Zeng Haiquan Chen Hongbin Ji | 2016 | Cell Research2016,26,10: | 9 |
| 4 | Preparation and electrochemical characterization of ultrathin WO3-x/C nanosheets as anode materials in lithium ion batteries显示文摘 | Keyan Bao Wutao Mao Guangyin Liu Liqun Ye Haiquan Xie Shufang Ji Dingsheng Wang Chen Chen Yadong Li | 2017 | Nano Research2017,10,6: | 4 |
| 5 | Multibeam water column data research in the Taixinan Basin:Implications for the potential occurrence of natural gas hydrate显示文摘A multi beam sonar survey is carried out in the continental slope of the Taixinan Basin to obtain submarine topographic and water column data. The data are processed to obtain water column images. Anomalous water column images, displaying plume characteristics, are found in gas hydrate enriched areas in the Taixinan Basin.This indicates the presence of natural gas resources in the Taixinan Basin. The multibeam sonar system is shown to provide an accurate and effective approach for detecting sub-sea gas hydrate. | Yilan Chen Jisheng Ding Haiquan Zhang Qiuhua Tang Xinghua Zhou Xiaoyu Liu | 2019 | Acta Oceanologica Sinica2019,38,5: | 4 |
| 6 | Scalable and Identifier/Locator-Splitting Routing Protocol for Mobile Ad Hoc Networks显示文摘In the traditional Internet Protocol (IP) architecture, there is an overload of IP semantic problems. Existing solutions focused mainly on the infrastructure for the fixed network, and there is a lack of support for Mobile Ad Hoc Networks (MANETs). To improve scalability. a routing protocol for MANETs is presented based on a locator named Tree-structure Locator Distance Vector (TLDV). The hard core of this routing method is the identifier/locator split by the Distributed Hash Table (DHT) method, which provides a scalable routing service. The node locator indicates its relative location in the network and should be updated whenever topology changes. Locator space is organized as a tree-structure, and the basic routing operation of the TLDV protocol is presented. TLDV protocol is compared to some classical routing protocols for MANETs on the NS2 platform. Results show that TLDV has better scalability. | Wang Haiquan Chen Meng Hu Junshun Xia Chunhe | 2012 | China Communications2012,9,1: | 3 |
| 7 | Copeptin in the assessment of acute lung injury and cardiogenic pulmonary edema显示文摘 | Qionghua Lin Fengming Fu Haiquan Chen Biao Zhu | 2012 | Respiratory Medicine2012,,9: | 2 |
| 8 | Tumor-associated macrophages provide a suitable microenvironment for non-small lung cancer invasion and progression显示文摘 | Rui Wang Jie Zhang Sufeng Chen Meng Lu Xiaoyang Luo Shihua Yao Shilei Liu Ying Qin Haiquan Chen | 2011 | Lung Cancer2011,,2: | 2 |
| 9 | Department of thoracic surgery two operation methods to analysis[J]of cardiopulmonary complications in elderly patients after surgery显示文摘 | Lin Wanli Chen Ying He Haiquan | | 0,,: | 1 |
| 10 | Ni-Catalyzed Cross Coupling ofAryl Grignard Reagents with Aryl Halides in a Nonpolar Solvent and an Efficient Synthesis of Biaryls Under Neat Conditions显示文摘 | WU Qiang JIN Rizhe KANG Chuanqing CHEN Wenhui BIAN Zheng MA Xiaoye DING Jinying GUO Haiquan QIU Xuepeng GAO Llanxun | 2016 | Chemical Research in Chinese Universities2016,32,1: | 1 |
| 11 | Damageidentification of ribbed plate retailing wall based on damagecharacter vector显示文摘 | CHEN Jiangong XU Qian ZHANG Haiquan | 2014 | Electronic Journal of GeotechnicalEngineering2014,19,: | 1 |
| 12 | The Preliminary Study of Interferon-γ Gene Transfection to Human Tenon's Capsule Fibroblasts in Vitro显示文摘 | Yuqing Lan, Jian Ge, Mingkai Lin, Jianliang Zheng, Huiyi Chen, Haiquan Liu, Jing Wei , Yanyan LiZhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou 510060, China Sun Yat-Sen Memorial Hospital, Sun Yat-sen University of Medical Sciences, Guangzhou 510120, China | 2000 | 眼科学报2000,16,3: | 1 |
| 13 | Electrochemical synthesis of selenocyanated imidazo[1,5-a]quinolines under metal catalyst-and chemical oxidant-free conditions显示文摘Reported herein is the first example of electrochemical selenocyanation of imidazo[1,5-a]quinolines with KSeCN under metal catalyst-and chemical oxidant-free conditions.This sustainable strategy shows a broad scope and great compatibility with functional groups,and affords synthetically and biologically important selenocyanated imidazo[1,5-a]quinolines in good to excellent yields with cheap graphite and Ni plates as the electrodes.The gram-scale synthesis was also successfully conducted,which might demonstrate the potential value of this electrochemical protocol. | Jinjin Zhang Huiqiao Wang Yaru Chen Haiquan Xie Chenghua Ding Jiajing Tan Kun Xu | 2020 | Chinese Chemical Letters2020,31,6: | 1 |
| 14 | Preparation of unsaturated polyester/graphite nanosheet conducting composite under electric field显示文摘 | Haiquan Wang Hongyan Zhang Guohua Chen | 2007 | Composites Part A:Applied Science and Manufacturing2007,38,10: | 1 |
| 15 | Generalized Correntropy for Robust Adaptive Filtering显示文摘 | Chen Badong Xing Lei Zhao Haiquan | 2015 | Eprint Arxiv2015,,: | 1 |
| 16 | The platinum-based treatments for advanced non-small cell lung cancer, is low/negative ERCC1 expression better than high/positive ERCC1 expression? A meta-analysis显示文摘 | Sufeng Chen Jie Zhang Rui Wang Xiaoyang Luo Haiquan Chen | 2010 | Lung Cancer2010,,1: | 1 |
| 17 | Electric field-induced orientation of graphite nanosheets in a polymer matrix显示文摘 | Wang Haiquan Chen Guohua | 2007 | Compos Sci Techn2007,68,: | 1 |
| 18 | 显示文摘 | Wang Changzheng Chen Zhong Hu Haiquan | 2009 | Physica B: Condensed Matter2009,404,21: | 1 |
| 19 | Pattern of lymphatic spread in thoracic esophageal squamous cell carcinoma: A single-institution experience显示文摘 | Bin Li Haiquan Chen Jiaqing Xiang Yawei Zhang Chenguang Li Haichuan Hu Yang Zhang | 2012 | The Journal of Thoracic and Cardiovascular Surgery2012,,4: | 1 |
| 20 | Adenovirus Ad-p53AIP1-mediated gene therapy and its regulation of p53-MDM2interactions显示文摘 | Yunbo Jiang Huihua Chen Haiquan Jia Yuanji Xu Gang Liu Yan Wang Xiaohe Yang Yinglin Lu | 2010 | Experimental and Therapeutic Medicine2010,,2: | 1 |