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| 1 | Osteoimmunomodulatory effects of biomaterial modification strategies on macrophage polarization and bone regeneration显示文摘Biomaterials as bone substitutes are always considered as foreign bodies that can trigger host immune responses.Traditional designing principles have been always aimed at minimizing the immune reactions by fabricating inert biomaterials.However,clinical evidence revealed that those methods still have limitations and many of which were only feasible in the laboratory.Currently,osteoimmunology,the very pioneering concept is drawing more and more attention-it does not simply regard the immune response as an obstacle during bone healing but emphasizes the intimate relationship of the immune and skeletal system,which includes diverse cells,cytokines,and signaling pathways.Properties of biomaterials like topography,wettability,surface charge,the release of cytokines,mediators,ions and other bioactive molecules can impose effects on immune responses to interfere with the skeletal system.Based on the bone formation mechanisms,the designing methods of the biomaterials change from immune evasive to immune reprogramming.Here,we discuss the osteoimmunomodulatory effects of the new modification strategies—adjusting properties of bone biomaterials to induce a favorable osteoimmune environment.Such strategies showed potential to benefit the development of bone materials and lay a solid foundation for the future clinical application. | Yajuan Xie Cheng Hu Yi Feng Danfeng Li Tingting Ai Yulei Huang Xiaodan Chen Lijia Huang Jiali Tan | 2020 | Regenerative Biomaterials2020，7，3： | 22 |
| 2 | Diamond Raman laser:a promising high-beam-quality and low-thermal-effect laser显示文摘Stimulated Raman-scattering-based lasers provide an effective way to achieve wavelength conversion.However,thermally induced beam degradation is a notorious obstacle to power scaling and it also limits the applicable range where high output beam quality is needed.Considerable research efforts have been devoted to developing Raman materials,with diamond being a promising candidate to acquire wavelength-versatile,high-power,and high-quality output beam owing to its excellent thermal properties,high Raman gain coefficient,and wide transmission range.The diamond Raman resonator is usually designed as an external-cavity pumped structure,which can easily eliminate the negative thermal effects of intracavity laser crystals.Diamond Raman converters also provide an approach to improve the beam quality owing to the Raman cleanup effect.This review outlines the research status of diamond Raman lasers,including beam quality optimization,Raman conversion,thermal effects,and prospects for future development directions. | Yulan Li Jie Ding Zhenxu Bai Xuezong Yang Yuqi Li Jingling Tang Yu Zhang Yaoyao Qi Yulei Wang Zhiwei Lu | 2021 | High Power Laser Science and Engineering2021，9，3： | 7 |
| 3 | Effect of Temperature on the Synthesis of SiC Coating on Carbon Fibers by the Reaction of SiO with the Deposited Pyrolytic Carbon Layer显示文摘The influence of reaction temperature on the preparation of SiC coating on carbon fibers by the reaction of silicon monoxide with the deposited pyrolytic carbon (PyC) layer has been discussed.With rising reaction temperature,the thickness of SiC layer increases and the SiC grain is coarsening.The apparent activation energy for the synthesis of SiC layer is about 103.3 kJ/mol.The oxidation resistance of carbon fiber can be improved by the SiC/PyC layers significantly.The initial oxidation temperature of the SiC/PyC coated carbon fiber is about 300℃ higher than that of the uncoated carbon fiber.The oxidation of the SiC/PyC coated carbon fiber is owing to the diffusion of oxygen through the cracks generated by the mismatch of thermal expansion. | Hejun Li,Haibo Ouyang,Lehua Qi,Yulei Zhang,Zhengjia Li and Jianfeng Wei C/C Composites Research Center,Key Laboratory of Ultrahigh Temperature Composites,Northwestern Polytechnical University,Xi an 710072,China | 2010 | Journal of Materials Science & Technology2010，26，3： | 5 |
| 4 | Methanogenic archaea and sulfate reducing bacteria induce severe corrosion of steel pipelines after hydrostatic testing显示文摘Complex interactions within a microbial consortium can induce severe corrosion in oil pipelines.This study investigated the mechanism of microbiologically influenced corrosion(MIC)that led to failure of X52 steel pipelines after hydrostatic testing.Laboratory hydrostatic testing with untreated lake water and underground water were used to simulate and study the events that led to the actual corrosion.Biofilm analysis,weight loss,and several electrochemical measurements demonstrated rapid corrosion rates after hydrostatic testing.Analysis of microbial community structures revealed that methanogenic archaea and sulfate reducing bacteria(SRB),introduced by the hydrotest water,formed corrosive biofilms on X52 steel coupon surfaces that induced severe pitting. | Enze Zhou Jianjun Wang Masoumeh Moradi Huabing Li Dake Xu Yuntian Lou Jinheng Luo Lifeng Li Yulei Wang Zhenguo Yang Fuhui Wang Jessica A.Smith | 2020 | Journal of Materials Science & Technology2020，47，13： | 5 |
| 5 | Protective effect of Jiaweibugan decoction against diabetic peripheral neuropathy显示文摘Oxygen free radical damage is regarded as a direct or indirect common pathway associated with diabetic neuropathy and is the main cause of complications in peripheral neuropathies. We speculate that Jiaweibugan decoction has a significant effect in treating diabetic peripheral neuropathy through an anti-oxidative stress pathway. In this study, a diabetic rat model was established by intraperitoneal injection of streptozotocin. Rats were treated with Jiaweibugan decoction via intragastric administration. The levels of malondialdehyde and glutathione, which are indirect indexes of oxidative stress, in serum were determined using a colorimetric method. The expression levels of nuclear factor kappa B p65 mRNA and p38 mitogen-activated protein kinase, which are oxidative stress associated factors, in the dorsal root ganglion of spinal S 4-6 segments were evaluated by reverse-transcriptase polymerase chain reaction and immunohistochemistry. Results showed that, Jiaweibugan decoction significantly ameliorated motor nerve conduction velocity in diabetic rats, effectively decreased malondialdehyde levels in serum and the expression of nuclear factor kappa B p65 mRNA and p38 mitogen-activated protein kinase mRNA in the dorsal root ganglion, and increased glutathione levels in serum. Therefore, our experimental findings indicate that Jiaweibugan decoction plays an anti-oxidative stress role in the diabetic peripheral neuropathy process, which has a protective effect on peripheral nerve injury. | Yu Wang Zeqi Chen Renqun Ye Yulei He Yuhong Li Xinjian Qiu | 2013 | Neural Regeneration Research2013，8，12： | 5 |
| 6 | Mullite Oxidation Resistant Coating for SiC-coated Carbon/Carbon Composites by Supersonic Plasma Spraying显示文摘To improve the oxidation resistance of carbon/carbon (C/C) composites, mullite coating was prepared on the surface of SiC-coated C/C composites by supersonic plasma spraying. Phases and microstructures of mullite coating were characterized by X-ray diffraction (XRD) and scanning electron microscopy (SEM). The coating primarily consists of a single phase of mullite (3Al2O3-2SiO2). The SEM results show that mullite coating was continuous and well bonded with the SiC inner layer without penetrating crack. Mullite coating exhibited good oxidation resistance. After 98.5 h oxidation at 1773 K and 9 thermal shock cycles between 1773 K and room temperature, the weight loss of the coated C/C composites was only 2.57%. | Chao Ma Hejun Li Heng Wu Qiangang Fu Can Sun Xiaohong Shi Yulei Zhang Zhengzhong Zhang Jun Tao Zhihai Han | 2013 | Journal of Materials Science & Technology2013，29，1： | 4 |
| 7 | SiC-Si-ZrSiO_4 Multiphase Oxidation Protective Coating for Carbon/Carbon Composites显示文摘In order to improve the anti-oxidation property of carbon/carbon (C/C) composites,a novel SiC-Si-ZrSiO_4 multiphase oxidation protective coating was produced on the surface of C/SiC coated carbon/carbon compos- ites by a pack cementation technique.The phase composition and microstructure of the as-prepared coatings were characterized by XRD (X-ray diffraction),SEM (scanning electron microscopy) and EDS (energy dis- persive spectroscopy).Oxidation behavior of the multiphase coated C/C composites was also investigated. It showed that the as-prepared coating characterized by excellent oxidation resistance and thermal shock re- sistance could effectively protect C/C composites from oxidation at 1773 K for 57 h in air and endure the thermal cycle between 1773 K and room temperature for 12 times,whereas the corresponding weight loss is only 1.47%.The excellent oxidation protective ability of the SiC-Si-ZrSiO_4 coating could be attributed to the C/SiC gradient inner layer and the multiphase microstructure of the coating. | Yulei ZHANG Hejun LI Qiangang FU Kezhi LI Dangshe HOU | 2008 | Journal of Materials Science & Technology2008，24，6： | 4 |
| 8 | Oxidation Protective C/SiC/Si-SiC Multilayer Coating for Carbon/Carbon Composites Applying at 1873 K显示文摘A C/SiC/Si-SiC multilayer coating for protecting carbon/carbon(C/C) composites against oxidation was prepared by slurry and pack cementation.X-ray diffraction(XRD) and energy dispersive spectroscopy(EDS) analysis showed that the inner coating obtained from the slurry and pack cementation was a C/SiC gradient layer acting as bonding layer,and the exterior coating formed in the second pack cementation was a Si-SiC double phase coating.Oxidation tests at 1873 K in air showed that the coating exhibited excellent oxidation protective ability and thermal shock resistance.The coating could effectively protect C/C composites from oxidation at 1873 K in air for 170 h and undergo the thermal cycling between 1873 K and room temperature for 8 cycles.The weight loss of the coated C/C composites is due to the formation of cracks and holes in the coating and the volatilization of SiO2 glass at high temperature. | Yulei Zhang,Hejun Li,Xinfa Qiang and Kezhi Li C/C Composites Research Center,State Key Laboratory of Solidification Processing,Northwestern Polytechnical University,Xi an 710072,China | 2010 | Journal of Materials Science & Technology2010，26，12： | 4 |
| 9 | Oxidation and Mechanical Properties of SiC/SiC-MoSi_2-ZrB_2 Coating for Carbon/Carbon Composites显示文摘To improve oxidation resistance of carbon/carbon(C/C) composites,a SiC/SiC-MoSi_2-ZrB_2 double-layer ceramic coating was prepared on C/C composites by two-step pack cementation.The phase compositions and microstructures of as-prepared multilayer coating were characterized by X-ray diffraction and scanning electron microscopy.The oxidation resistance at 1773 K and the effect of thermal shock between 1773 K and room temperature on mechanical performance of coated specimens were investigated.The results show that the SiC/SiC-MoSi_2-ZrB_2 coating exhibits dense structure and is composed of SiC,Si,MoSi_2 and ZrB_2·It can protect C/C composites from oxidation at 1773 K for more than 510 h with weight loss of 0.5%.The excellent anti-oxidation performance of the coating is due to the formation of SiO_2-ZrSiO_4 complex glassy film.The coating can also endure the thermal shocks between 1773 K and room temperature for 20 times with residual flexural strength of 86.1%. | Xiyuan Yao Hejun Li Yulei Zhang Yongjie Wang | 2014 | Journal of Materials Science & Technology2014，30，2： | 4 |
| 10 | Mechanics Unloading Analysis and Experimentation of a New Type of Parallel Biomimetic Shoulder Complex显示文摘The structure design for high ratio of carrying capacity to deadweight is one of the challenges for the bionic mechanism,while the problem concerning high carrying capacity has not yet be solved for the existing shoulder complex.A new type biomimetic shoulder complex,which adopts 3-PSS/S(P for prismatic pair,S for spherical pair) spherical parallel mechanism(SPM),is proposed.The static equilibrium equations of each component are established by using the vector method and the equations for constrain forces with certain load are solved.Then the constrain force on the middle limb and that on the side limbs are compared in order to verify the unloading performance of the mechanism.In addition,the prototype mechanism of the shoulder complex is developed,and the force feedback experiment is conducted to verify the static analysis,which indicates that the middle limb suffers most of the external force and the effect of mechanics unloading is achieved.The 3-PSS/S spherical parallel mechanism is presented for the shoulder complex,and the realization of mechanics unloading is benefit for the improvement of the carrying capacity of the shoulder complex. | HOU Yulei LI Zhisen WANG Yi ZHANG Wenwen ZENG Daxing ZHOU Yulin | 2016 | Chinese Journal of Mechanical Engineering2016，29，4： | 4 |
| 11 | W-Mo-Si/SiC Oxidation Protective Coating for Carbon/Carbon Composites显示文摘W-Mo-Si/SiC 双层氧化防护涂层 forcarbon/carbon ( C/C ) composites 被二拍子的圆舞包装硬化 technique.XRD ( X-raydiffraction )准备, SEM (扫描电子显微镜学)结果涂层由第一步包装硬化获得了的表演是薄内部缓冲区层原文如此与一些裂缝和毛孔,并且一个新阶段(W_xMo_( 1-x )) Si2 出现在第二步包装硬化以后。氧化测试显示出那,在在在为 175 h 并且在在 18 次的 1773 K 和房间温度之间的热骑车的 1773 K 的空中的氧化以后, W-Mo-Si/SiC 涂的 C/C composites 的重量损失仅仅是2.06% .Theoxidation W-Mo-Si/SiC 涂层的保护的失败在涂层被归因于一些可穿透的裂缝的形成。 | Dangshe HOU Kezhi LI Hejun LI Qiangang FU Jian WEI Yulei ZHANG | 2007 | Journal of Materials Science & Technology2007，23，4： | 3 |
| 12 | Identification and molecular characterization of two novel mutations in COL1A2 in two Chinese families with osteogenesis imperfecta显示文摘成骨 imperfecta (OI,也已知的同样易碎的骨头疾病) 主要被变化在二种类型引起我编码类型的 pro-1 (I) 和 pro-2 (I) 链的骨胶原基因, COL1A1 和 COL1A2 我骨胶原分别地。有正染色体的主导的 OI 的二个中国家庭被识别并且描绘。连接分析在染色体 7q21.3-q22.1 上揭示了两个家庭的连接到 COL1A2。Mutational 分析用直接 DNA 顺序分析被执行。二个新奇错误感觉变化, c.3350A > G 和 c.3305G > C,在 exon 被识别在二个家庭的 49 COL1A2 分别地。c.3305G > C 变化在 codon 由丙氨酸残余(A) 导致了 glycine 残余(G) 的替换 1102 (p.G1102A ) ,它被发现在另外的家庭被变异进丝氨酸(S) , argine (R) ,丁氨二酸酸(D) ,或缬氨酸(V) 。c.3350A > G 变体可以是导致 p.Y1117C 的一个 de novo 变化。两个变化在各自的家庭与 OI 共同分离,并且没在 100 正常控制被发现。G1102 和 Y1117 残余高度 evolutionarily 从 zebrafish 被保存到人。Mutational 分析没在 COX-2 基因(OI 的修饰词基因) 识别任何变化。这研究识别引起 OI 的二新奇变化 p.G1102A 和 p.Y1117C,显著地扩展引起 OI 的 COL1A2 变化的光谱,并且有在 OI 的出生前的诊断的一个重要含意。 | Zhenping Xu Yulei Li Xiangyang Zhang Fanming Zeng Mingxiong Yuan Mugen Liu Qing Kenneth Wang Jing Yu Liu | 2011 | Journal of Genetics and Genomics2011，38，4： | 3 |
| 13 | Chemical Synthesis of Proteins Containing 300 Amino Acids显示文摘Chemical synthesis of proteins containing up to 300 amino acids may cover 30%—50%of all the proteins encountered in biomedical studies and may provide an alternate approach to the usually used recombinant expression teclmology,vastly expanding the chemical space of the latter.In the present review article,we tried to survey the recent progresses made for more rapid synthesis of increasingly long peptides and more efficient ligation of multiple peptide segments.The developments of seminal methods by many research groups have greatly contributed to the recent breakthroughs in the successful total synthesis of a number of functionally important proteins,such as oligoubiquitins,bacterial GroEL/ES chaperones,and mirror-image DNA polymerases.Through these studies,a potential bottleneck has also been recognized for the chemical synthesis of large proteins,namely,how to ensure that each peptide segment from a large protein avoids unfavorable aggregation when dissolved in aqueous solution.Many new methods,such as removable backbone modification(RBM)strategy have been developed to overcome this bottleneck,while more studies need to be carried out to develop more effective and less costly methods that ultimately,may lead to fully automatable chemical synthesis of customized proteins of 300 amino acids bearing any artificial designs. | ZHANG Baochang LI Yulei SHI Weiwei WANG Tongyue ZHANG Feng LIU Lei | 2020 | Chemical Research in Chinese Universities2020，36，5： | 3 |
| 14 | SiC/Si-W-Mo coating for protection of C/C composites at 1873 K显示文摘In order to prevent carbon/carbon composites from oxidation at 1873 K, an efficient oxidation protective SiC/Si-W-Mo coating was prepared by a two-step pack cementation technique. The microstructures and the phase composition of the as-received multi-coating were examined by scanning electron microscopy (SEM) and X-ray diffraction (XRD). It is seen that the compact multi-coating is composed of α-SiC, Si, and (WxMo1-x)Si2. Oxidation test shows that, after oxidation at 1873 K in air for 102 h and thermal cycling between 1873 K and room temperature for 10 times, the weight loss of the SiC/Si-W-Mo coated C/C composites is only 0.26%. The invalidation of the multi-coating is attributed to the formation of penetrable cracks in the coating. | Dangshe Hou Kezhi Li Hejun Li Qiangang Fu Yulei Zhang | 2008 | Journal of University of Science and Technology Beijing2008，15，6： | 3 |
| 15 | Hundred-Joule-level,nanosecond-pulse Nd:glass laser system with high spatiotemporal beam quality显示文摘A 100-J-level Nd:glass laser system in nanosecond-scale pulse width has been constructed to perform as a standard source of high-fluence-laser science experiments. The laser system, operating with typical pulse durations of 3–5 ns and beam diameter 60 mm, employs a sequence of successive rod amplifiers to achieve 100-J-level energy at 1053 nm at3 ns. The frequency conversion can provide energy of 50-J level at 351 nm. In addition to the high stability of the energy output, the most valuable of the laser system is the high spatiotemporal beam quality of the output, which contains the uniform square pulse waveform, the uniform flat-top spatial fluence distribution and the uniform flat-top wavefront. | Sensen Li Yulei Wang Zhiwei Lu Lei Ding Yi Chen Pengyuan Du Dexin Ba Zhenxing Zheng Xin Wang Hang Yuan Chengyu Zhu Weiming He Dianyang Lin Yongkang Dong Dengwang Zhou Zhenxu Bai Zhaohong Liu Can Cui | 2016 | High Power Laser Science and Engineering2016，4，1： | 3 |
| 16 | Structural modification and antitumor activity of antimicrobial peptide HYL显示文摘HYL derived from the venom of the solitary bee Hylaeus signatus(Hymenoptera:Colletidae)is anα-helical antimicrobial peptide with 16 residues.To explore whether HYL can be applied in anti-tumor therapy,we synthesized HYL and further modified its structure by using a solid-phase synthesis method,and then evaluated their antitumor activities.Firstly,we identified the key residues of HYL by alanine scanning strategy,and then a series of stapled peptides were synthesized by hydrocarbon stapling strategy without destroying the key residues.All the stapled peptides of HYL showed significant improvement not only inα-helicity,but also in antitumor activity and protease resistance when compared to the parent peptide HYL.The results showed that hydrophobicity and amphiphilicity are important factors affecting the antitumor activity of HYL,and the stapling strategy can significantly affect the proteolytic stability and helicity of HYL.What’s more,we find that the stapled peptides HYL-14,HYL-16 and HYL-18 show a promising prospect for novel anti-tumor drug development. | Minghao Wu Qing Chen Yingdi Wang Yulei Li Xia Zhao Qi Chang | 2020 | Chinese Chemical Letters2020，31，5： | 2 |
| 17 | Carrier dynamics and terahertz photoconductivity of doped silicon measured by femtosecond pump-terahertz probe spectroscopy显示文摘The carrier dynamics and terahertz photoconductivity in the n-type silicon (n-Si) as well as in the p-type Silicon (p-Si) have been investigated by using femtosecond pump-terahertz probe technique. The measurements show that the relative change of terahertz transmission of p-Si at low pump power is slightly smaller than that of n-Si,due to the lower carrier density induced by the recombination of original holes in the p-type material and the photogenerated electrons. At high pump power,the bigger change of terahertz transmission of p-Si originates from the greater mobility of the carriers compared to n-Si. The transient photoconductivities are calculated and fit well with the Drude-Smith model,showing that the mobility of the photogenerated carriers decreases with the increasing pump power. The obtained results indicate that femtosecond pump-terahertz probe technique is a promising method to investigate the carrier dynamics of semiconductors. | ZHOU QingLi SHI YuLei LI Tong JIN Bin ZHAO DongMei ZHANG CunLin | 2009 | Science China(Physics,Mechanics & Astronomy)2009，52，12： | 2 |
| 18 | A Novel Interacting Multiple-Model Method and Its Application to Moisture Content Prediction of ASP Flooding显示文摘In this paper,an interacting multiple-model(IMM)method based on datadriven identification model is proposed for the prediction of nonlinear dynamic systems.Firstly,two basic models are selected as combination components due to their proved effectiveness.One is Gaussian process(GP)model,which can provide the predictive variance of the predicted output and only has several optimizing parameters.The other is regularized extreme learning machine(RELM)model,which can improve the overfitting problem resulted by empirical risk minimization principle and enhances the overall generalization performance.Then both of the models are updated continually using meaningful new data selected by data selection methods.Furthermore,recursive methods are employed in the two models to reduce the computational burden caused by continuous renewal.Finally,the two models are combined in IMM algorithm to realize the hybrid prediction,which can avoid the error accumulation in the single-model prediction.In order to verify the performance,the proposed method is applied to the prediction of moisture content of alkali-surfactant-polymer(ASP)flooding.The simulation results show that the proposed model can match the process very well.And IMM algorithm can outperform its components and provide a nice improvement in accuracy and robustness. | Shurong Li Yulei Ge Renlin Zang | 2018 | Computer Modeling in Engineering & Sciences2018，，1： | 2 |
| 19 | Hole-pinned defect-dipoles induced colossal permittivity in Bi doped SrTiO3 ceramics with Sr deficiency显示文摘Bi doped SrTiO3 ceramics with Sr deficiency,i.e.Sr1-1.5xBixTiO3(x=0,0.01,0.05,0.1),were prepared via conventional solid-state reaction route.A colossal permittivity(CP)over 104 with low dielectric loss less than 0.05wasobtained in x=0.05 Sr1-1.5xBixTiO3 ceramics.In addition,the dielectric constant is maintained at a value greater than 104 in the range of 102-105 Hz and almost frequency independent.Phase structure analysis and density functional theory calculations suggest that the Bi·Sr-V'Sr-Bi·Sr defect complex with hole-pinned defect-dipoles maybe responsible for the high-performance CP properties.This work gives a new way to achieve high performance CP materials in ABO3 perovskite ceramics. | Yulong Qiao Weili Li Yulei Zhang Lu Jing Chang Gao Wenping Cao Dan Xu Weidong Fei | 2020 | Journal of Materials Science & Technology2020，44，9： | 2 |
| 20 | Increased prediction value of biomarker combinations for the conversion of mild cognitive impairment to Alzheimer's dementia显示文摘Background:Progression of mild cognitive impairment(MCI)to Alzheimer's disease(AD)dementia can be predicted by clinical features and a combination of biomarkers may increase the predictive power.In the present study,we investigated whether the combination of olfactory function and plasma neuronal-derived exosome(NDE)Aβ1-42 can best predict progression to AD dementia.Methods:Eighty-seven MCI patients were enrolled and received cognitive assessment at 2-year and 3-year follow-up to reevaluate cognition.In the meanwhile,80 healthy controls and 88 AD dementia patients were enrolled at baseline as well to evaluate the diagnose value in cross-section.Olfactory function was evaluated with the sniffin sticks(SS-16)and Aβ142 levels in NDES were determined by ELISA.Logistic regression was performed to evaluate the risk factors for cognitive decline in MCI at 2-year and 3-year revisits.Results:In the cross cohort,lower SS-16 scores and higher AB142 levels in NDES were found in MCI and AD dementia compared to healthy controls.For the longitudinal set,8 MCI individuals developed AD dementia within 2 years,and 16 MCI individuals developed AD dementia within 3 years.The two-parameter combination of SS-16 scores and Aβ1-42 level in NDEs showed better prediction in the conversion of MCI to AD dementia at 2-year and 3-year revisits.Moreover,after a 3-year follow-up,SS-16 scores also significantly predicted the conversion to AD dementia,where lower scores were associated with a 10-fold increased risk of developing AD dementia(p=0.006).Similarly,higher AB1-42 levels in NDES in patients with MCI increased the risk of developing AD dementia by 8.5-fold(p=0.002).Conclusion:A combination of two biomarkers NDE AB1-42 and SS-16 predicted the conversion of MCI to AD dementia more accurately.These findings have critical implications for understanding the pathophysiology of AD dementia and for developing preventative treatments for cognitive decline. | Aonan Zhao Yuanyuan Li Yi Yan Yinghui Qiu Binyin Li Wei Xu Ying Wang Jun Liu Yulei Deng | 2020 | Translational Neurodegeneration2020，9，3： | 2 |
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