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| 1 | Herbgenomics: A stepping stone for research into herbal medicine显示文摘From the prehistoric era until the publishing of the Compendium of Materia Medica and the first scientific Nobel Prize in the Chinese mainland for Tu's discovery on anti-malarial tablets,each milestone and stepping stone in the developmental history of herbal medicine involved intrepid exploration,bold hypothesis formulation,and cautious verification.After thousands of years of discovery and development,herbal research has entered a new era—the era of herbgenomics.Herbgenomics combines herbal and genomic research,bridging the gap between traditional herbal medicine and cutting-edge omics studies.Therefore,it provides a general picture of the genetic background of traditional herbs,enabling researchers to investigate the mechanisms underlying the prevention and treatment of human diseases from an omics perspective. | Haoyu Hu Xiaofeng Shen Baosheng Liao Lu Luo Jiang Xu Shilin Chen | 2019 | Science China(Life Sciences)2019，62，7： | 13 |
| 2 | Memristive crossbar array with applications in image processing显示文摘A memristor is a kind of nonlinear resistor with memory capacity.Its resistance changes with the amount of charge or flux passing through it.As the fourth fundamental circuit element,it has huge potential applications in many fields,and has been expected to drive a revolution in circuit theory.Through numerical simulations and circuitry modeling,the basic theory and properties of memristors are analyzed,and a memristor-based crossbar array is then proposed.The array can realize storage and output for binary,grayscale and color images.A series of computer simulations demonstrates the effectiveness of the proposed scheme.Owing to the advantage of the memristive crossbar array in parallel information processing,the proposed method is expected to be used in high-speed image processing. | HU XiaoFang DUAN ShuKai WANG LiDan LIAO XiaoFeng | 2012 | Science China(Information Sciences)2012，55，2： | 13 |
| 3 | Event-Triggered Differentially Private Average Consensus for Multi-agent Network显示文摘This paper investigates the differentially private problem of the average consensus for a class of discrete-time multi-agent network systems(MANSs). Based on the MANSs,a new distributed differentially private consensus algorithm(DPCA) is developed. To avoid continuous communication between neighboring agents, a kind of intermittent communication strategy depending on an event-triggered function is established in our DPCA. Based on our algorithm, we carry out the detailed analysis including its convergence, its accuracy, its privacy and the trade-off between the accuracy and the privacy level, respectively. It is found that our algorithm preserves the privacy of initial states of all agents in the whole process of consensus computation. The trade-off motivates us to find the best achievable accuracy of our algorithm under the free parameters and the fixed privacy level. Finally, numerical experiment results testify the validity of our theoretical analysis. | Aijuan Wang Xiaofeng Liao Haibo He | 2019 | IEEE/CAA Journal of Automatica Sinica2019，6，1： | 12 |
| 4 | Allele-aware chromosome-level genome assembly of Artemisia annua reveals the correlation between ADS expansion and artemisinin yield显示文摘Artemisia annua is the major natural source of artemisinin,an anti-malarial medicine commonly used worldwide.Here,we present chromosome-level haploid maps for two A.annua strains with different artemisinin contents to explore the relationships between genomic organization and artemisinin production.High-fidelity sequencing,optical mapping,and chromatin conformation capture sequencing were used to assemble the heterogeneous and repetitive genome and resolve the haplotypes of A.annua.Approximately 5o,ooo genes were annotated for each haplotype genome,and a triplication event that occurred approximately 58.12million years ago was examined for the first time in this species.A total of 3,903,467-5,193,414 variants(SNPs,indels,and structural variants)were identified in the 1.5-Gb genome during pairwise comparison between haplotypes,consistent with the high heterozygosity of this species.Genomic analyses revealed a correlation between artemisinin concents and the copy number of amorpha-4,11-dienes ynthasegenes.This correlation was further confirmed by resequencing of 36A.annua samples with varied artemisinin contents.Circular consensus sequencing of transcripts facilitated the detection of paralog expression.Collectively,our study provides chromosome-level allele-aware genome assemblies for two A.annua strains and new insights into the biosynthesis of artemisinin and its regulation,which will contribute to conquering malaria worldwide. | Baosheng Liao Xiaofeng Shen Li Xiang Shuai Guo Shiyu Chen Ying Meng Yu Liang Dandan Ding Junqi Bai Dong Zhang Tomasz Czechowski Yi Li Hui Yao Tingyu Mai Caroline Howard Chao Sun Haitao Liu Jiushi Liu Jin Pei Jihai Gao Jigang Wang Xiaohui Qiu Zhihai Huang Hongyi Li Ling Yuan Jianhe Wei lan Graham Jiang Xu Boli Zhang Shilin Chen | 2022 | Molecular Plant2022，15，8： | 9 |
| 5 | Overactive bladder symptom score to evaluate efficacy of solifenacin for the treatment of overactive bladder symptoms显示文摘 | Liu Ming Wang Jianye Yang Yong An Ruihua Wen Jianguo Guan Zhichen Zheng Shaobin Wang Dongwen Song Bo Liao Limin Guo Hongqian Xiao Jiaquan Sun Yinghao Shen Zhoujun Kong Chuize He Dalin Huang Yiran Wang Xiaofeng Zhang Xu Li Hanzhong Huang Jian Zhao Xiaokun Zeng Puqing Song Xishuang Ye Zhangqun | 2014 | Chinese Medical Journal2014，，2： | 7 |
| 6 | Multiple effects of nitrate amendment on the transport, transformation and bioavailability of antimony in a paddy soil-rice plant system显示文摘Nitrate(NO3^(-))is known to be actively involved in the processes of mineralization and heavy metal transformation;however,it is unclear whether and how it affects the bioavailability of antimony(Sb)in paddy soils and subsequent Sb accumulation in rice.Here,the effects of NO3^(-)on Sb transformation in soil-rice system were investigated with pot experiments over the entire growth period.Results demonstrated that NO3^(-)reduced Sb accumulation in brown rice by 15.6%compared to that in the control.After amendment with NO3^(-),the Sb content in rice plants increased initially and then gradually decreased(in roots by 46.1%).During the first 15 days,the soil p H increased,the oxidation of Sb(Ⅲ)and sulfides was promoted,but the reduction of iron oxide minerals was inhibited,resulting in the release of adsorbed and organic-bound Sb from soil.The microbial arsenite-oxidizing marker gene aox B played an important role in Sb(Ⅲ)oxidation.From days 15 to 45,after NO3^(-)was partially consumed,the soil p H decreased,and the reductive dissolution of Fe(Ⅲ)-bearing minerals was enhanced;consequently,iron oxide-bound Sb was transformed into adsorbed and dissolved Sb species.After day 45,NO3^(-)was completely reduced,Sb(V)was evidently reduced to Sb(Ⅲ),and green rust was generated gradually.Thus,the available Sb decreased due to its enhanced affinity for iron oxides.Moreover,NO3^(-)inhibited the reductive dissolution of iron minerals,which ultimately caused low Sb availability.Therefore,NO3^(-)can chemically and biologically reduce the Sb availability in paddy soils and alleviate Sb accumulation inrice.This study provides a potential strategy for decreasing Sb accumulation in rice in the Sb-contaminated sites. | Xiaofeng Zhang Tongxu Liu Fangbai Li Xiaomin Li Yanhong Du Huanyun Yu Xiangqin Wang Chuanpin Liu MiFeng Bing Liao | 2021 | Journal of Environmental Sciences2021，33，2： | 6 |
| 7 | In situ generated thrombin in the protein corona of zeolites: Relevance of the functional proteins to its biological impact显示文摘到 nanomaterial 表面的血浆蛋白质的吸附在他们的简历功能上有大影响。然而,有在在蛋白质日冕和材料的生物身份的功能的蛋白质之间的关系的有限理解。这里,我们证明在里面 situ 在 Ca 沸石表面的蛋白质日冕产生了凝血酵素显示一个钙依赖者,不平常地高(3,000 NIH U/mg ) procoagulant 活动,它对 antithrombin 释放是甚至稳定的。移开包含的 Ca < 啜 class= “ a-plus-plus ” > 在沸石的 2+ 由 antithrombin 导致释放。我们的观察建议凝血酵素活动能被无机的表面和阳离子调整。最重要地,我们的发现在蛋白质日冕和材料的 procoagulant 活动显示在 biomolecules 之间的连接,提供为沸石 hemostatics 的 procoagulant 机制的一个新分子的基础。 | Yunlong Li Xiaofeng Liao Xiaoxi Zhang Guicen Ma Shuai Zuo Liping Xiao Galen D. Stucky Zhugang Wang Xian Chen Xiaoqiang Shang Jie Fan | 2014 | Nano Research2014，7，10： | 5 |
| 8 | Natural orifice transluminal endoscopic surgery in urology: The Chinese experience显示文摘Objective:To describe the Chinese experience of natural orifice transluminal endoscopic surgery(NOTES)in urology.Methods:From December 2008 to May 2017,35 animal experiments and 305 clinical surgeries of NOTES or natural orifices specimen extractions(NOSE)were performed in China.The animal experiments included five kidney biopsies,24 nephrectomies and six partial nephrectomies.The clinical surgeries included 12 transvaginal NOSE(TV-NOSE),266 hybrid transvaginal NOTES(TV-NOTES)and 27 pure TV-NOTES.The TV-NOSE procedure was performed in five transumbilical laparoendoscopic single-site(U-LESS)nephrectomies,four suprapubic-assisted laparoendoscopic single-site surgery(SA-LESS)nephroureterectomies,and three laparoscopic radical cystectomies.The hybrid TV-NOTES procedure included 210 nephrectomies,31 adrenalectomies,eight nephroureterectomies,13 partial nephrectomies,and four heminephrectomies.The pure TV-NOTES procedure included five renal cyst decortications and 22 nephrectomies.Results:A total of 29 animal experiments were successfully performed.One partial nephrectomy was converted to standard laparoscopic surgery.Two kidney biopsies and two nephrectomies were unsuccessful.A total of 297 clinical surgeries were successfully performed.Six patients who underwent hybrid TV-NOTES were converted to open surgery.Two patients who underwent pure TV-NOTES were converted to SA-LESS.There were 22 major complications,16 occurred intraoperatively and six postoperatively.The mean visual analog score(VAS)of 48 h after the operation was 2.5 points in TV-NOSE,2.3 points in hybrid TV-NOTES and 1.7 points in pure TV-NOTES.The mean follow-up of 50.6(3.0-87.0)months showed that all patients were in good condition.The umbilicus scars were nearly invisible in TV-NOSE and hybrid TV-NOTES.The vaginal incision healed well.Conclusions:TV-NOSE and TV-NOTES are feasible,safe,and effective with little injury,low pain,fast recovery,and good cosmetic outcomes in properly selected patients.They are worth consideration for urological clinical practice. | Xiaofeng Zou Guoxi Zhang Tianpeng Xie Yuanhu Yuan Rihai Xiao Gengqing Wu Xiaoning Wang Hui Xu Folin Liu Yuting Wu Yunfeng Liao Quanliang Liu Yinghao Sun Bo Yang Linhui Wang Chuanliang Xu Xiaofeng Gao | 2020 | Asian Journal of Urology2020，7，1： | 5 |
| 9 | A new technology for hard-rock tunneling based on drilling and hydraulic impact breaking显示文摘In order to realize the safety, high efficiency and rapidity of hard rock tunneling, we propose the drilling &hydraulic impact hard-rock tunneling(DHIHT) technology and method. Based on the LS-DYNA explicit module and APDL programming, the key parameters of DHIHT, including drilling spacing and drilling radius, were investigated. The simulation results show that: the drilling spacing should not exceed0.20 m-larger distances weaken the actual breaking effect; the best drilling radius is about 0.035 m, larger or smaller distances would both decrease the effect of drilling-hole free surfaces. The field impact breaking experiments were conducted in Baitaizi township granite quarry, Jinzhou, Liaoning province,China. The experiment results indicate that DHIHT is a feasible method for hard-rock tunneling, but its efficiency still needs to be further optimized and improved. | Long Risheng Sun Shaoni Lian Zisheng Liao Yaoyao Qin Xiaofeng | 2015 | International Journal of Mining Science and Technology2015，25，6： | 4 |
| 10 | An Optimized Vertical Handoff Algorithm Based on Markov Process in Vehicle Heterogeneous Network显示文摘In order to solve the problem the existing vertical handoff algorithms of vehicle heterogeneous wireless network do not consider the diversification of network's status, an optimized vertical handoff algorithm based on markov process is proposed and discussed in this paper. This algorithm takes into account that the status transformation of available network will affect the quality of service(Qo S) of vehicle terminal's communication service. Firstly, Markov process is used to predict the transformation of wireless network's status after the decision via transition probability. Then the weights of evaluating parameters will be determined by fuzzy logic method. Finally, by comparing the total incomes of each wireless network, including handoff decision incomes, handoff execution incomes and communication service incomes after handoff, the optimal network to handoff will be selected. Simulation results show that: the algorithm proposed, compared to the existing algorithm, is able to receive a higher level of load balancing and effectively improves the average blocking rate, packet loss rate and ping-pang effect. | MA Bin DENG Hong XIE Xianzhong LIAO Xiaofeng | 2015 | China Communications2015，12，4： | 4 |
| 11 | Short-DNA Specific Blocker PCR for Efficient and Simple Enrichment of Cell Free Fetal DNAs with Short Lengths显示文摘As an inn ate characteristic,DNA length has attracted more and more atte ntion.The length of some import ant biomarkers such as ctDNA(Circulating tumor DNA)and cffDNA(Cell free fetal DNA)is shorter than that of cell-free DNA.Researchers have utilized the differe nee in length to in crease the abunda nee of ctDNA or cffDNA in total cell-free DNA to overcome the difficulties in detecti on due to their low abundance. | Yangwei Liao Xiaofeng Tang Zhihao Ming Lida Ren Wei Zhang Xianjin Xiao | 2021 | Chinese Journal of Chemistry2021，39，8： | 2 |
| 12 | A chaos-based image encryption algorithm with variable control parameters显示文摘 | Yong Wang Kwok-Wo Wong Xiaofeng Liao Tao Xiang Guanrong Chen | 2008 | Chaos, Solitons and Fractals2008，，4： | 2 |
| 13 | Period analysis of the Logistic map for the finite field显示文摘Usually, the security of traditional cryptography which works on integer numbers and chaotic cryptosystem which works on real numbers is worthy of study. But the classical chaotic map over the real domain has a disadvantage that the calculation accuracy of the floating point number can be doubled when the map is implemented by computer. This is a serious drawback for practical application. The Logistic map is a classical chaotic system and it has been used as a chaotic cipher in the real number field. This inevitably leads to the degradation of finite precision under computer environment, and it is also very difficult to guarantee security.To solve these drawbacks, we extend the Logistic map to the finite field. In this paper, we consider the Logistic map for the finite field N = 3~n, and analyze the period property of sequences generated by the Logistic map over ZN. Moreover, we discuss the control parameters which may influence the behavior of the mapping, and show that the Logistic map over ZN may be suitable for application by performance analysis. Ultimately, we find that there exists an automorphic map between two Logistic maps with the different control parameters, which makes them suitable for sequence generator in cryptosystem. The automorphic sequence generated algorithm based on the Logistic map over ZN is designed and analyzed in detail. These sequences can be used in the pseudorandom number generator, the chaotic stream cipher, and the chaotic block cipher, etc. | Bo YANG Xiaofeng LIAO | 2017 | Science China(Information Sciences)2017，60，2： | 2 |
| 14 | On the security of a novel key agreement protocol based on chaotic maps显示文摘 | Tao Xianga Kwok-Wo Wongb Xiaofeng Liao | 2009 | Chaos Solitons Fract2009，40，2： | 1 |
| 15 | A secure arithmetic coding based on Markov model 显示文摘 | DUAN Lili LIAO Xiaofeng XIANG Tao | | Communications on Nonlinear Science and Numerical Simulation0，6，： | 1 |
| 16 | A novel block cryptosystem based on iterating a chaotic map显示文摘 | Xiang Tao Liao Xiaofeng Tang Guoping | 2006 | Physics Letters A2006，，349： | 1 |
| 17 | Hopf bifurcation in a Volterra prey-predator model with strong kernel显示文摘 | LI Shaowen LIAO Xiaofeng L1 Chunguang | 2004 | Chaos Solitons & Fraetals2004，22，： | 1 |
| 18 | Comprehensive Multi-Level Exploration of Buried Active Faults:an Example of the Yinchuan Buried Active Fault显示文摘The paper introduces the steps and methods of multi-approach,multi-level exploration of buried faults in thick Quaternary sediment regions by taking the test exploration of the Yinchuan active fault as example.Based on the comprehensive analyses of previous data,we choose the Xinqushao Village of Xingqing District of Yinchuan City as the test site for the comprehensive exploration.Firstly,we adopted shallow seismic investigation with group intervals of 10m,5m and 1m to gradually trace layer by layer the master fault of the Yinchuan buried fault from a deep depth to a shallow depth where drilling could be used.Then,with composite geological profile drilling,we determined the precise location and dip angle of the fault.The drilling show the buried depth of the upper offset point is 8.3m.Finally,large-scale trenching revealed that the actual buried depth of the upper offset point of the fault is 1.5m from the ground surface and there are paleoearthquake events of 5 stages.Combined with the preliminary result of corresponding sample age,we conclude the Yinchuan buried fault is a mid to late Holocene active fault. | Chai Chizhang Meng Guangkui Du Peng Wang Yin Liu Baojin Shen Weihua LeiQiyun Liao Yuhua Zhao Chengbin Feng Shaoying Zhang Xuehui Xie Xiaofeng | 2007 | Earthquake Research in China2007，21，3： | 1 |
| 19 | An improved chaotic cryptosystem with external key 显示文摘 | Tao Xiang Kwok - wo Wong Xiaofeng Liao | 2008 | Communications in Nonlinear Science and Numerical Simulation2008，，13： | 1 |
| 20 | An Improved Chaotic Cryptosystem with External Key显示文摘 | Xiang Tao Wong K W Liao Xiaofeng | 2008 | Communications in Nonlinear Science and Numerical Simulation2008，13，9： | 1 |
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