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| 1 | Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial显示文摘 | Paul Y Kwo Eric J Lawitz Jonathan McCone Eugene R Schiff John M Vierling David Pound Mitchell N Davis Joseph S Galati Stuart C Gordon Natarajan Ravendhran Lorenzo Rossaro Frank H Anderson Ira M Jacobson Raymond Rubin Kenneth Koury Lisa D Pedicone Clifford | 2010 | The Lancet2010，，9742： | 3 |
| 2 | Sex-specific differences in white matter microvascular integrity after ischaemic stroke显示文摘background and purpose Functional outcomes after ischaemic stroke are worse in women,despite adjusting for differences in comorbidities and treatment approaches.White matter microvascular integrity represents one risk factor for poor long-term functional outcomes after ischaemic stroke.The aim of the study is to characterise sex-specific differences in microvascular integrity in individuals with acute ischaemic stroke.Methods A retrospective analysis of subjects with acute ischaemic stroke and brain MRI with diffusion-weighted(DWI)and dynamic-susceptibility contrast-enhanced(DSC)perfusion-weighted imaging obtained within 9 hours of last known well was performed.In the hemisphere contralateral to the acute infarct,normal-appearing white matter(NAWM)microvascular integrity was measured using the K_(2) coefficient and apparent diffusion coefficient(ADC)values.Regression analyses for predictors of K_(2) coefficient,DWI volume and good outcome(90-day modified Rankin scale(mRS)score<2)were performed.results 105 men and 79 women met inclusion criteria for analysis.Despite no difference in age,women had increased NAWM K_(2) coefficient(1027.4 vs 692.7×10^(-6)/s;p=0.006).In women,atrial fibrillation(β=583.6;p=0.04)and increasing NAWM ADC(β=4.4;p=0.02)were associated with increased NAWM K_(2) coefficient.In multivariable regression analysis,the K_(2) coefficient was an independent predictor of DWI volume in women(β=0.007;p=0.01)but not men.Conclusions In women with acute ischaemic stroke,increased NAWM K_(2) coefficient is associated with increased infarct volume and chronic white matter structural integrity.Prospective studies investigating sex-specific differences in white matter microvascular integrity are needed. | Mark R Etherton Ona Wu Pedro Cougo Svetlana Lorenzano Hua Li Lisa Cloonan Mark J R J Bouts Arne Lauer Ken Arai Eng H Lo Steve K Feske Karen L Furie Natalia S Rost | 2019 | Stroke & Vascular Neurology2019，4，4： | 2 |
| 3 | Differential expression of components of the cardiomyocyte adrenomedullin/intermedin receptor system following blood pressure red-uction in Nodeificient hypertension显示文摘 | Abdelrahman A M David B Lisa R S | 2005 | JPET Fast Forward2005，12，3： | 1 |
| 4 | Combing new technologies for determination of phytoplankton community structure in the northern gulf of Mexico显示文摘 | JASON H S LISA C TAMMI L R | 2005 | Journal Plankton2005，41，： | 1 |
| 5 | Preventing the Sex-ual Transmission of HIV-1 with Topical Microbicides:Another Piece of the Equation显示文摘 | Lisa C R Sharon L H Charlene S D | 2007 | EDITORIAL COM-MENTARY2007，96，： | 1 |
| 6 | Applications of array biosensor for detection of food allergens显示文摘 | LISA C CHRIS R T LIGLER S | 2004 | Journal of AOAC International2004，87，6： | 1 |
| 7 | Achieving relationship marketing effectiveneas in business-to-busineas exchanges显示文摘 | ROBERT P W LISA'S K KENNETH R | 2008 | Journal of the Acadmy of Science Sunmmer2008，36，2： | 1 |
| 8 | Clearance of hepatitis B eantigen in patients with chronic hepatitis B and genotypes A,B,C,D and F显示文摘 | Stephen E L Josephine P S Lisa R B | 2007 | Gastroenterology2007，133，5： | 1 |
| 9 | Differential expression of components of the cardiomyocyte adrenomedullin/intermedin receptor systerm following blood pressure reduction in nitric oxide-deficient hypertension显示文摘 | ZHAO Y Y DAVID B LISA R S | 2006 | J Pharmacol Exp Ther2006，316，： | 1 |
| 10 | A two-phase study evaluating the relationship between Thimerosal-containing vaccine administration and the risk for an autism spectrum disorder diagnosis in the United States显示文摘Background:Autism spectrum disorder(ASD)is defined by standardized criteria of qualitative impairments in social interaction,qualitative impairments in communication,and restricted and stereotyped patterns of behavior,interests,and activities.A significant number of children diagnosed with ASD suffer a loss of previously-acquired skills,which is suggestive of neurodegeneration or a type of progressive encephalopathy with an etiological pathogenic basis occurring after birth.To date,the etiology of ASD remains under debate,however,many studies suggest toxicity,especially from mercury(Hg),in individuals diagnosed with an ASD.The present study evaluated concerns about the toxic effects of organic-Hg exposure from Thimerosal(49.55%Hg by weight)in childhood vaccines by conducting a two-phased(hypothesis generating/hypothesis testing)study with documented exposure to varying levels of Thimerosal from vaccinations.Methods:A hypothesis generating cohort study was undertaken to evaluate the relationship between exposure to organic-Hg from a Thimerosal-containing Diphtheria-Tetanus-acellular-Pertussis(DTaP)vaccine in comparison to a Thimerosal-free DTaP vaccine administered,from 1998 through 2000,for the risk of ASD as reported in the Vaccine Adverse Event Reporting System(VAERS)database(phase I).A hypothesis testing case–control study was undertaken to evaluate the relationship between organic-Hg exposure from Thimerosal-containing hepatitis B vaccines administered at specific intervals in the first six months of life among cases diagnosed with an ASD and controls born between 1991 through 1999 in the Vaccine Safety Datalink(VSD)database(phase II).Results:In phase I,it was observed that there was a significantly increased risk ratio for the incidence of ASD reported following the Thimerosal-containing DTaP vaccine in comparison to the Thimerosal-free DTaP vaccine.In phase II,it was observed that cases diagnosed with an ASD were significantly more likely than controls to receive increased organic-Hg from Thimerosal-containing hepatitis B vaccine administered within the first,second,and sixth month of life.Conclusions:Routine childhood vaccination is an important public health tool to reduce the morbidity and mortality associated with infectious diseases,but the present study provides new epidemiological evidence supporting an association between increasing organic-Hg exposure from Thimerosal-containing childhood vaccines and the subsequent risk of an ASD diagnosis. | David A Geier Brian S Hooker Janet K Kern Paul G King Lisa K Sykes Mark R Geier | 2013 | Translational Neurodegeneration2013，2，1： | 1 |
| 11 | Clinical process analysis and activity-based costing at a heart center显示文摘 | Lisa R Andreas J Tommy S | 2002 | J Med Syst2002，26，4： | 1 |
| 12 | Femtoscopy in Relativistic Heavy Ion Collisions显示文摘 | Lisa M Prat t S Soltz R | 2005 | Ann Rev Nucl Part Sci2005，55，： | 1 |
| 13 | Differential expression of components of the cardiomyocyte adrenomedullin/intermedin receptor systerm following blood pressure reduction in nitric oxide-deficient hypertension显示文摘 | ZHAO Y Y DAVID B LISA R S | 2006 | J Pharmacol Exp Ther2006，316，： | 1 |
| 14 | Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial显示文摘 | Paul Y Kwo Eric J Lawitz Jonathan McCone Eugene R Schiff John M Vierling David Pound Mitchell N Davis Joseph S Galati Stuart C Gordon Natarajan Ravendhran Lorenzo Rossaro Frank H Anderson Ira M Jacobson Raymond Rubin Kenneth Koury Lisa D Pedicone Clifford | 2010 | The Lancet2010，，9742： | 1 |
| 15 | Insulin resistance, the metabolic syndrome, and Incident cardiovascular events in l he Framingham offspring study显示文摘 | Martin K R James B M Lisa M S | 2005 | Diabetes2005，54，11： | 1 |
| 16 | Prediction of renal insufficiency in Pima Ind diabetes mellitus显示文摘 | Alexander S Goldfarb R Lisa P | 2002 | American Journal of Kidney Diseases2002，40，2： | 1 |
| 17 | Regulation of the synthesis and activity of ammonia monooxygenase in nigrosomonas europaea by altering pH to affect NH3 acailability显示文摘 | Lisa Y S Daniel J A Michael R H | 1997 | Applied and Environmental Microbiology1997，63，11： | 1 |
| 18 | Inflammatory markers and risk of heart failure in elderly subjects without prior myocardial infacetion显示文摘 | Ramachandran S Lisa M Ronenn R | 2003 | Circulation2003，107，： | 1 |
| 19 | Oral vaccination of mice against tetanus with recombinant Lactococcus lactis显示文摘 | KAREN R LISA M C KARIN M S | 1997 | Nature Biotechnology1997，15，： | 1 |
| 20 | Clinical process analysis and activity-based costing at a heart center显示文摘 | Lisa R Andreas J Tommy S | | 0，，04： | 1 |
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