|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Deficient plastidic fatty acid synthesis triggers cell death by modulating mitochondrial reactive oxygen species显示文摘 | Jian Wu Yuefeng Sun Yannan Zhao Jian Zhang Lilan Luo Meng Li Jinlong Wang Hong Yu Guifu Liu Liusha Yang Guosheng Xiong Jian-Min Zhou Jianru Zuo Yonghong Wang Jiayang Li | 2015 | Cell Research2015，25，5： | 13 |
| 2 | Effects of combined chemical design(Cu addition) and topographical modification(SLA) of Ti-Cu/SLA for promoting osteogenic, angiogenic and antibacterial activities显示文摘Cu has been proved to possess various beneficial biological activities, while sandblasting and acid etching(SLA) is widely used to modify the commercial dental implant in order to improve osseointegration. Based on the above, a novel antimicrobial dental implant material, Ti-Cu alloy, was treated with SLA, to combine chemical design(Cu addition) and topographical modification(SLA). In this work, the effects of SLA treated Ti-Cu alloys(Ti-Cu/SLA) on osteogenesis, angiogenesis and antibacterial properties were evaluated from both in vitro and in vivo tests, and Ti/SLA and Ti-Cu(without SLA) were served as control groups. Benefiting by the combined effects of chemical design(Cu addition) and micro-submicron hybrid structures(SLA),Ti-Cu/SLA had significantly improved inhibitory effects on oral anaerobic bacteria(P. gingivalis and S.mutans) and could induce upregulation of osteogenic-related and angiogenic-related genes expression in vitro. More importantly, in vivo studies also demonstrated that Ti-Cu/SLA implants had wonderful biological performance. In the osseointegration model, Ti-Cu/SLA implant promoted osseointegration via increasing peri-implant bone formation and presenting good bone-binding, compared to Ti/SLA and Ti-Cu implants. Additionally, in the peri-implantitis model, Ti-Cu/SLA effectively resisted the bone resorption resulted from bacterial infection and meanwhile promoted osseointegration. All these results suggest that the novel multiple functional Ti-Cu/SLA implant with rapid osseointegration and bone resorption inhibition abilities has the potential application in the future dental implantation. | Rui Liu Yulong Tang Hui Liu Lilan Zeng Zheng Ma Jun Li Ying Zhao Ling Ren Ke Yang | 2020 | Journal of Materials Science & Technology2020，47，12： | 6 |
| 3 | Life History Recorded in the Vagino-cervical Microbiome Along with Multi-omes显示文摘The vagina contains at least a billion microbial cells,dominated by lactobacilli.Here we perform metagenomic shotgun sequencing on cervical and fecal samples from a cohort of 516 Chinese women of reproductive age,as well as cervical,fecal,and salivary samples from a second cohort of 632 women.Factors such as pregnancy history,delivery history,cesarean section,and breastfeeding were all more important than menstrual cycle in shaping the microbiome,and such information would be necessary before trying to interpret differences between vagino-cervical microbiome data.Greater proportion of Bifidobacterium breve was seen with older age at sexual debut.The relative abundance of lactobacilli especially Lactobacillus crispatus was negatively associated with pregnancy history.Potential markers for lack of menstrual regularity,heavy flow,dysmenorrhea,and contraceptives were also identified.Lactobacilli were rare during breastfeeding or post-menopause.Other features such as mood fluctuations and facial speckles could potentially be predicted from the vagino-cervical microbiome.Gut and salivary microbiomes,plasma vitamins,metals,amino acids,and hormones showed associations with the vagino-cervical microbiome.Our results offer an unprecedented glimpse into the microbiota of the female reproductive tract and call for international collaborations to better understand its long-term health impact other than in the settings of infection or pre-term birth. | Zhuye Jie Chen Chen Lilan Hao Fei Li Liju Song Xiaowei Zhang Jie Zhu Liu Tian Xin Tong Kaiye Cai Zhe Zhang Yanmei Ju Xinlei Yu Ying Li Hongcheng Zhou Haorong Lu Xuemei Qiu Qiang Li Yunli Liao Dongsheng Zhou Heng Lian Yong Zuo Xiaomin Chen Weiqiao Rao Yan Ren Yuan Wang Jin Zi Rong Wang Na Liu Jinghua Wu Wei Zhang Xiao Liu Yang Zong Weibin Liu Liang Xiao Yong Hou Xun Xu Huanming Yang Jian Wang Karsten Kristiansen Huijue Jia | 2022 | Genomics, Proteomics & Bioinformatics2022，20，2： | 2 |
| 4 | Effective shape-controlled synthesis of gallium selenide nanosheets by vapor phase deposition显示文摘The controlled synthesis of large and uniform gallium selenide(GaSe)crystals is crucial for its various applications based on the attractive properties of this emerging material.In this work,vapor phase growth of high-quality monolayer GaSe nanosheets with multiple shape and size is achieved by tuning the Ga/GaSe ratio in the precursor.A theoretical model based on density functional theory calculations and kinetic Wulff construction theory describe the observed shape evolution of the GaSe nanosheets.Results show that the Ga/Se ratio plays a critical role in the evolution of the domain shape and size.Moreover,the as-grown GaSe nanosheets show improved performance with photoresponse time less than 0.7 ms and responsibility up to 3,000 AW.This study presents a previously unexplored strategy for the controlled growth of two-dimensional(2D)GaSe nanosheets for promising applications in next-generation optoelectronics. | Lilan Tan Qingbo Liu Yufeng Ding Xiaogang Lin Wei Hu Meng-Qiu Cai Hong Zhou | 2020 | Nano Research2020，13，2： | 2 |
| 5 | Rnf20 deficiency in adipocyte impairs adipose tissue development and thermogenesis显示文摘RNF20,an E3 ligase critical for monoubiquitination of histone H2B at lysine 120(H2Bub),has been implicated in the regulation of various cellar processes;however,its physiological roles in adipocytes remain poorly characterized.Here,we report that the adipocyte-specific knockout of Rnf20(ASKO)in mice led to progressive fat toss,organomegaly and hyperinsulinemia.Despite signs of hyperinsulinemia,normal insulin sensitivity and improved glucose tolerance were observed in the young and aged CD-fed ASKO mice.In addition,high-fat diet-fed ASKO mice developed severe liver steatosis.Moreover,we observed that the ASKO mice were extremely sensitive to a cold environment due to decreased expression levels of brown adipose tissue(BAT)selective genes,including uncoupling protein 1(l/cpf),and impaired mitochondrial functions.Significantly decreased levels of peroxisome proliterator-activated receptor gamma(Ppary)were observed in the gonadal white adipose tissues(gWAT)from the ASKO mice,suggesting that Rnf20 regulates adipogenesis,at least in part,through Ppary.Rosiglitazone-treated ASKO mice exhibited increased fat mass compared to that of the non-treated ASKO mice.Collectively,our results illustrate the critical role of RNF20 in control of white and brown adipose tissue development and physiological function. | Xiaojuan Liang Cong Tao Jianfei Pan Lilan Zhang Lulu Liu Ying Zhao Yiping Fan Chunwei Cao Jiali Liu Jin Zhang Sin Man Lam Guanghou Shui Wanzhu Jin Wei Li Jianguo Zhao Kui Li Yanfang Wang | 2021 | Protein & Cell2021，12，6： | 1 |
| 6 | The Mathematic Models of the Kalman Filtering for Across-Fault Measurement显示文摘This paper makes a probe into the application of the Kalman filtering method to the data processing of across-fault measurements.On the basis of statistical regression,the mathematic and stochastic models of filtration are established by combining the regression method with Kalman filtering.In the filtering computation,not only the randomness of fault movements but also the time-dependent variation of environmental effects have been taken into consideration.By use of the adaptive filtering method,an estimation of the dynamic noise variance matrix is obtained through iteration.Models for one measuring line(leveling line or baseline),two measuring lines(both leveling lines or both baselines)and four measuring lines(two leveling lines and two baselines)are derived and established systematically.By means of these models,the data of across-fault measurements can be processed dynamically in real-time to provide the filtered values of height difference between benchmarks or baseline length at different time | You Lilan,Liu Dajie,Huang Jia’na,Liu Xue and Zhou KechangInstitute of Crustat Dynamics,SSB,Beijing 100085,China Wuhan Technical University of Surveying and Mapping,Wuhan 430070,China National Center for Seismic Data and Inforraanon,SSB,Beijing 100045,China | 1994 | Earthquake Research in China1994，8，3： | 1 |
| 7 | Resource Management Framewordk for Manufacturing Grid显示文摘 | Liu Lilan Yu Tao Shi Zhanbei | 2004 | Journal of Southeast University(English Edition)2004，20，3： | 1 |
| 8 | Chaotic improved PSObased multi-objective optimization for minimization of power losses and L index in power systems显示文摘 | Gonggui Chen Lilan Liu Peizhu Song | 2014 | Energy Conversion and Management2014，86，： | 1 |
| 9 | Cervicovaginal microbiome dynamics after taking oral probiotics显示文摘The vaginal microbiota is less complex than the gut microbiota,and the colonization of Lactobacillus in the female vagina is considered to be critical for reproductive health.Oral probiotics have been suggested as promising means to modulate vaginal homeostasis in the general population.In this study,60 Chinese women were followed for over a year before,during,and after treatment with the probiotics Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14.Shotgun metagenomic data of 1334 samples from multiple body sites did not support a colonization route of the probiotics from the oral cavity to the intestinal tract and then to the vagina.Our analyses enable the classification of the cervicovaginal microbiome into a stable state and a state of dysbiosis.The microbiome in the stable group steadily maintained a relatively high abundance of Lactobacilli over one year,which was not affected by probiotic intake,whereas in the dysbiosis group,the microbiota was more diverse and changed markedly over time.Data from a subset of the dysbiosis group suggests this subgroup possibly benefited from supplementation with the probiotics,indicating that probiotics supplementation can be prescribed for women in a subclinical microbiome setting of dysbiosis,providing opportunities for targeted and personalized microbiome reconstitution. | Chen Chen Lilan Hao Zhe Zhang Liu Tian Xiaowei Zhang Jie Zhu Zhuye Jie Xin Tong Liang Xiao Tao Zhang Xin Jin Xun Xu Huanming Yang Jian Wang Karsten Kristiansen Huijue Jia | 2021 | Journal of Genetics and Genomics2021，48，8： | 1 |
| 10 | Comprehensive parameter identification of feed servo systems with friction based on responses of the worktable显示文摘 | Liu Lilan Wu Ziying | 2015 | Mechanical Systems and Signal Process2015，6465，： | 1 |
| 11 | Strain - dependent nonlinear damping and application to dynamic analysis of elastic linkage mechanism 显示文摘 | Liu Hongzhao Wang Jianping Zhang Zhongming Yuan Daning Liu Lilan | 2005 | Journal of Sound and Vibration2005，281，： | 1 |
| 12 | Chaotic improved PSO-based multi-objective optimization for minimization of power losses and L index in power systems显示文摘 | Chen Gonggui Liu Lilan Song Peizhu | 2014 | Energy Conversion and Management2014，，86： | 1 |
| 13 | Resource management framework for manufacturing grid显示文摘 | LIU Lilan YU Tao SHI Zhanbei | 2004 | Journal of Southeast University2004，20，3： | 1 |
| 14 | Resource management framework for manufacturing grid显示文摘 | LIU LILAN YU TAO SHI ZHANBEI | 2004 | English Edition Journal of Southeast University2004，20，3： | 1 |
| 15 | Resource managment framework for manufacturing grid显示文摘 | Liu Lilan Yu Tao Shi Zhanbei | 2004 | English Edition Journal of Southeast University2004，20，3： | 1 |
| 16 | Chaotic Im- proved PSO-based Multi-objective Optimization for Mini- mization of Power Losses and L Index in Power Systems 显示文摘 | Chen Gonggui Liu Lilan Song Peizhu | 2014 | Energy Conversion and Management2014，86，10： | 1 |
| 17 | Adaptive cluster synchro-nization for a complex dynamical network with delays andstochastic perturbation 显示文摘 | Yu Le Tu Lilan Liu Hongfang | 2013 | The European Physical Jour-nal B2013，86，4： | 1 |
| 18 | Protein arginine methyltransferase 3 fine-tunes the assembly/disassembly of pre-ribosomes to repress nucleolar stress by interacting with RPS2B in arabidopsis显示文摘Ribosome biogenesis,which takes place mainly in the nucleolus,involves coordinated expression of preribosomal RNAs(pre-rRNAs)and ribosomal proteins,pre-rRNA processing,and subunit assembly with the aid of numerous assembly factors.Our previous study showed that the Arabidopsis thaliana protein arginine methyltransferase AtPRMT3 regulates pre-rRNA processing;however,the underlying molecular mechanism remains unknown.Here,we report that AtPRMT3 interacts with Ribosomal Protein S2(RPS2),facilitating processing of the 90S/Small Subunit(SSU)processome and repressing nucleolar stress.We isolated an intragenic suppressor of atprmt3-2,which rescues the developmental defects of atprmt3-2 while produces a putative truncated AtPRMT3 protein bearing the entire N-terminus but lacking an intact enzymatic activity domain We further identified RPS2 as an interacting partner of AtPRMT3,and found that loss-of-function rps2a2b mutants were phenotypically reminiscent of atprmt3,showing pleiotropic developmental defects and aberrant pre-rRNA processing.RPS2B binds directly to pre-rRNAs in the nucleus,and such binding is enhanced in atprmt3-2.Consistently,multiple components of the 90S/SSU processome were more enriched by RPS2B in atprmt3-2,which accounts for early pre-rRNA processing defects and results in nucleolar stress.Collectively,our study uncovered a novel mechanism by which AtPRMT3 cooperates with RPS2B to facilitate the dynamic assembly/disassembly of the 90S/SSU processome during ribosome biogenesis and repress nucleolar stress. | Runlai Hang Zhen Wang Chao Yang Lilan Luo Beixin MO Xuemei Chen Jing Sun Chunyan Liu Xiaofeng Cao | 2021 | Molecular Plant2021，14，2： | 0 |
| 19 | Synchronization-Based Topology Identification of Uncertain Stochastic Delay Complex Networks显示文摘In this paper, topology identification of general weighted complex network with time-varying delay and stochastic perturbation,which is a zero-mean real scalar Wiener process, is investigated. Based on the adaptive-feedback control method, the stochastic Lyapunov stability theory and the ito formula, some synchronous criteria are established, which guarantee the asymptotical mean square synchronization of the drive network and the response network with stochastic disturbances, as well as identify the topological structure of the uncertain general drive complex network. Finally, numerical simulations are presented to verify the correctness and effectiveness of the proposed scheme. | LIU Hongfang TU Lilan YU Le | 2013 | Wuhan University Journal of Natural Sciences2013，18，4： | 0 |
| 20 | A Cross Layer Protocol for Fast Identification of Blocked Tags in Large-Scale RFID Systems显示文摘Blocker tag attack is one of the denial-of-service(DoS)attacks that threatens the privacy and security of RFID systems.The attacker interferes with the blocked tag by simulating a fake tag with the same ID,thus causing a collision of message replies.In many practical scenarios,the number of blocked tags may vary,or even be small.For example,the attacker may only block the important customers or high-value items.To avoid the disclosure of privacy and economic losses,it is of great importance to fast pinpoint these blocked ones.However,existing works do not take into account the impact of the number of blocked tags on the execution time and suffer from incomplete identification of blocked tags,long identification time or privacy leakage.To overcome these limits,we propose a cross layer blocked tag identification protocol(CLBI).CLBI consists of multiple rounds,in which it enables multiple unblocked tags to select one time slot and concurrently verify them by using tag estimation in physical layer.Benefiting from the utilization of most collision slots,the execution time can be greatly reduced.Furthermore,for efficient identification of blocked tags under different proportions,we propose a hybrid protocol named adaptive cross layer blocked tag identification protocol(A-CLBI),which estimates the remaining blocked tag in each round and adjusts the identification strategy accordingly.Extensive simulations show that our protocol outperforms state-of-the-art blocked tags identification protocol. | Chu Chu Zhong Huang Rui Xu Guangjun Wen Lilan Liu | 2020 | Computers, Materials & Continua2020，，9： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员