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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020，28，3： | 516 |
| 2 | Abnormal activation of the synuclein-gamma gene in hepatocellular carcinomas by epigenetic alteration.显示文摘 | Zhao W Liu H Liu W Wu Y Chen W Jiang B Zhou Y Xue R Luo C Wang L Jiang JD Liu J | 2006 | 中国生物学文摘2006，20，4： | 31 |
| 3 | Destabilization of strigolactone receptor DWARF14 by binding of ligand and E3-1igase signaling effector DWARF3显示文摘 | Li-Hua Zhao X Edward Zhou Wei Yi Zhongshan Wu Yue Liu Yanyong Kang Li Hou Parker W de Waal Suling Li Yi Jiang Adrian Scaffidi Gavin R Flematti Steven M Smith Vinh Q Lam Patrick R Griffin YonghongWang Jiayang Li Karsten Melcher H Eric Xu | 2015 | Cell Research2015，25，11： | 7 |
| 4 | Common non-synonymous polymorphisms in the BRCA1 Associated RING Domain (BARD1) gene are associated with breast cancer susceptibility:a case-control analysis显示文摘The BRCA1 Associated RING Domain(BARD1) gene has been identified as a high penetrance gene for breast cancer, whose germline and somatic mutations were reported in both non-BRCA1/2 hereditary site-specific and sporadic breast cancer cases. BARD1 plays a crucial role in tumor repression, along with its heterodimeric partner BRCA1. In the current study, we tested the hypothesis that common non-synonymous polymorphisms in BARD1 are associated with breast cancer susceptibility in a case-control study of 507 patients with incident breast cancer and 539 frequency-matched cancer-free controls in Chinese women. We genotyped all three common(minor allele frequency (MAF) > 0.10) non-synonymous polymorphisms(Pro24Ser, Arg378Ser, and Val507Met) in BARD1. We found that the BARD1 Pro24Ser variant genotypes(24Pro/Ser and 24Ser/Ser) and Arg378Ser variant homozygote 378Ser/Ser were associated with a significantly decreased breast cancer risk, compared with their wild-type homozygotes, respectively. Furthermore, a significant locus-locus interaction was evident between Pro24Ser and Arg378Ser (P-int = 0.032). Among the 378Ser variant allele carriers, the 24Pro/Pro wild-type homozygote was associated with a significantly increased breast cancer risk (adjusted OR = 1.81, 95% CI = 1.11-2.95), but the subjects having 24Pro/Ser or Ser/Ser variant genotypes had a significantly decreased risk(adjusted OR = 0.74, 95% CI = 0.56-0.99). In stratified analysis, this locus-locus interaction was more evident among subjects without family cancer history, those with positive estrogen receptor (ER) and individuals with negative progesterone receptor(PR). These findings indicate that the potentially functional polymorphisms Pro24Ser and Arg378Ser in BARD1 may jointly contribute to the susceptibility of breast cancer. | Huo, X Hu, Z. B Zhai, X. J Wang, Y Wang, S Wang, X. C Qin, J. W Chen, W. S Jin, G. F Liu, J. Y Gao, J Wei, Q. Y Wang, X. R Shen, H. B | 2007 | 南京医科大学学报(自然科学版)2007，27，7： | 3 |
| 5 | 发生在西方患者中的肺纤毛黏液结节性乳头状肿瘤具有BRAF和AKT1突变显示文摘纤毛黏液结节性乳头状肿瘤是一种罕见的肺外周病变,以乳头状结构和纤毛柱状细胞与黏液细胞、基底细胞混合为特征。常出现显著的肺泡腔内黏液,可能导致与黏液腺癌诊断上的混淆。诊断纤毛黏液结节性乳头状肿瘤的关键在于对具有纤毛柱状细胞的识别。 | Liu L Aesif S W Kipp B R 魏建国 刘勇 | 2017 | 临床与实验病理学杂志2017，33，1： | 2 |
| 6 | Construction of an AFLP genetic map with nearly complete genome coverage in Pinus taeda显示文摘 | Remington D L Wheten R W Liu B H | 1999 | Theoretical and Applied Genetics1999，98，： | 1 |
| 7 | The pharmacology effect and clinical development of huperzine A显示文摘 | LIU X L CHENG C R CAO W | 2006 | Hera Med2006，，2： | 1 |
| 8 | Studies on the toxic effects of pentachlorophenol on the biological activity of anaerobic granular sludge 显示文摘 | Liu X W He R Shen D S | 2008 | J Environ Manage2008，88，： | 1 |
| 9 | Wind-induced vibration of high-rise building with tuned mass damper including soil-structure interaction显示文摘 | Liu M Y Chiang W L Hwang J H Chu C R | 2008 | Journal of Wind Engineering and Industrial Aerodynamics2008，96，： | 1 |
| 10 | Study on the corrosion re- sistance of phytic acid conversion coating for magnesiu mal- loys 显示文摘 | Liu J R Guo Y N Huang W D | 2006 | Surface and Coatings Technology2006，201，34： | 1 |
| 11 | Self-evolution Neural Model 显示文摘 | Shuai J W Chen Z XI Liu R T | 1996 | Physics Letters-A1996，221，5： | 1 |
| 12 | Botulinum toxin type B micromechanosensor 显示文摘 | LIU W MONTANA V CHAPMAN E R | 2003 | Proceedings of the National Academy of Sciences of the United States of America2003，100，13： | 1 |
| 13 | High color rendering white light-emitting-diode illuminator using the red-emitting Eu^2+ -activated CaZnOS phosphors excited by blue LED 显示文摘 | Kuo T W Liu W R Chen T M | 2010 | Optics Express2010，18，8： | 1 |
| 14 | Prediction of prognosis in gallbladder carcinoma by CD147 and MMP-2 immunohistochemistry 显示文摘 | Wu W Wang R Liu H | 2009 | Med Oncol2009，26，2： | 1 |
| 15 | Homogeneous modification of cellulose with succinic anhydride in ionic liquid using4-dimethylaminopyridine as a catalyst显示文摘 | Li W Y Liu C F Sun R C | 2009 | Carbohydrate Polymers2009，78，3： | 1 |
| 16 | Molecular dynamics simulations of consolidation processes during fabrication of nanophase palladium显示文摘 | Liu C L Adams J B Siegal R W | 1994 | Nanostructured Materials1994，4，4： | 1 |
| 17 | Modeling the Dynamic Corrosion Process in Chloride Contaminated Concrete Structures显示文摘 | Liu T Weyers R W | 1998 | Cement and Concrete Rsearch1998，，3： | 1 |
| 18 | Eu Substitution and Particle Size Control of Y2O2S for the Excitation by UV Light Emitting Diodes显示文摘 | Chou T W Mylswamy S Liu R S | 2005 | Solid State Communications2005，136，： | 1 |
| 19 | Effect of electrode structure on performance of Si anode in Li-ion batteries: Si particle size and conductive additive显示文摘 | LIU W R GUO Z Z YOUNG W S | 2005 | Journal of Power Sources2005，140，1： | 1 |
| 20 | Diversity analysis for frequency-selective MIMO-OFDM systems with general spatial and temporal correlation model 显示文摘 | SADEK A K SU W LIU K J R | 2006 | IEEE Trans Commun2006，54，5： | 1 |
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