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| 1 | Brazing of C/C composite and Ti-6Al-4V with graphene strengthened AgCuTi filler:Effects of graphene on wettability,microstructure and mechanical properties显示文摘Graphene nanosheets(GNSs) strengthened AgCuTi composite filler(AgCuTi_G) was used to braze C/C composite and Ti-6Al-4V. The effects of GNSs on the wettability of AgCuTi_G filler on the C/C composite surface and the interfacial microstructure and mechanical properties of brazed joints were investigated. The results indicate that the addition of GNSs reduced the wettability of AgCuTi_G. The interfacial microstructure of brazed joints evolved with the addition of GNSs, where Ti_3Cu_4 and TiCu_4 were converted to TiCu and the thickness of the reaction layer adjacent to the base material decreased. The maximum shear strength of joints brazed at 0.3 wt% GNSs was 23.3 MPa(880℃/10 min). Further adding GNSs deteriorated the shear strength of the joints. Fracture of the joints occurred in the C/C composite substrate and the TiC layer adjacent to C/C composite. | Duo LIU Yanyu SONG Yinghao ZHOU Xiaoguo SONG Wei FU Jicai FENG | 2018 | Chinese Journal of Aeronautics2018，31，7： | 11 |
| 2 | Vacuum brazing of GH99 superalloy using graphene reinforced BNi-2 composite filler显示文摘A novel graphene reinforced BNi-2 composite filler was developed for brazing GH99 superalloy. The interfacial microstructure of brazed joints was analyzed by field emission scanning electron microscope and a transmission electron microscope. The effects of graphene addition on the microstructure evolution and mechanical properties of brazed joints were investigated, and the strengthening mechanism of graphene was analyzed. The results revealed that due to the addition of graphene, M23(C,B)6 compounds were synthesized in the solid solution and brittle boride precipitates near the brazing seam decreased.Graphene was effective in retarding solute atoms diffusion thus impeding the precipitation of borides.Furthermore, the low coefficient of thermal expansion(CTE) of graphene was conducive to relieve stress concentration of the brazed joints during the cooling process. The shear strengths of brazed joints were significantly improved by exerting the strengthening effect of graphene. The maximum shear strengths of the brazed joints were 410.4 MPa and 329.7 MPa at room temperature and 800?C, respectively. | Duo Liu Yanyu Song Bin Shi Qi Zhang Xiaoguo Song Hongwei Niu Jicai Feng | 2018 | Journal of Materials Science & Technology2018，34，10： | 10 |
| 3 | Clinical characteristics and survival of 5283 esophageal cancer patients: A multicenter study from eighteen hospitals across six regions in China显示文摘Objective:This study aimed to investigate the potential determining epidemiological and clinical risk factors affecting the survival of esophageal cancer(EC)patients across multiple hospitals in China.Methods:This was a multicenter study comprising of newly diagnosed EC cases from Beijing,Hebei,Henan,Hubei,Zhejiang,and Guangdong Province of China.Their baseline characteristics and treatment methods data were collected from their medical records.The EpiData software was used for data quality control.The Kaplan-Meier method was used to estimate their overall survival(OS),and the Cox’s proportional hazard regression model was used to estimate hazard ratios(HR)and 95%confidence interval(CI).Results:The 3-and 5-year OS rates of the 5283 investigated EC patients were 49.98%and 39.07%,respectively.Their median survival was 36.00 months.The median survival time of females was longer than that of males(females vs.males:45.00 vs.33.00,P<0.001).The 5-year OS rate of patients who never-smoked was higher than that of smokers(never-smokers vs smokers:40.73%vs.37.84%,P=0.001).There was no significant difference in the 5-year OS rate between drinkers and never-drinkers(drinkers vs never-drinkers:34.22%vs.29.65%,P=0.330).In multivariate analysis,pathological stage(stage II:HR=1.80,95%CI=1.40-2.31;stage III:HR=2.62,95%CI=2.06-3.34;stage IV:HR=3.90,95%CI=2.98-5.09),poor differentiation/undifferentiated(HR=1.34,95%CI=1.11-1.63),not married status(HR=2.45,95%CI=1.49-4.04),production and service personnel(HR=1.36,95%CI=1.01-1.83)and farming/fishing(HR=1.40,95%CI=1.12-1.76)were independent prognostic risk factors for poor EC survival.Tumors in the thoracic or abdominal part of the esophagus,female and family history of any cancer were independent factors predictive of a good EC OS.Conclusion:Gender,marital status,occupation,family history of any cancer,tumor topographical site,differentiation status,and pathological stage were associated with the survival rate of EC.This study reveals important clinical characteristics of esophageal cancer patients in China and provides helpful information for their clinical management and surveillance. | Yutong He Di Liang Lingbin Du Tiantian Guo Yanyu Liu Xibin Sun Ning Wang Min Zhang Kuangrong Wei Baoen Shan Wanqing Chen | 2020 | Cancer Communications2020，40，10： | 8 |
| 4 | Light absorption properties and potential sources of brown carbon in Fenwei Plain during winter 2018–2019显示文摘A distinctive kind of organic carbon aerosol that could absorb ultraviolet-visible radiation is called brown carbon(Br C),which has an important positive influence on radiative budget and climate change.In this work,we reported the absorption properties and potential source of Br C based on a seven-wavelength aethalometer in the winter of 2018–2019 at an urban site of Sanmenxia in Fenwei Plain in central China.Specifically,the mean value of Br C absorption coefficient was 59.6±36.0 Mm^(-1) at 370 nm and contributed 37.7%to total absorption,which made a significant impact on visibility and regional environment.Absorption coefficients of Br C showed double-peak pattern,and Br C had shown small fluctuations under haze days compared with clean days.As for the sources of Br C,Br C absorption coefficients expressed strong correlations with element carbon aerosols and primary organic carbon aerosols,indicating that most of Br C originated from primary emissions.The linear correlations between trace metal elements(K,As,Fe,Mn,Zn,and Pb)and Br C absorption coefficients further referred that the major sources of Br C were primary emissions,like coal burning,biomass burning,and vehicle emissions.The moderate relationship between Br C absorption coefficients and secondary organic aerosols suggested that secondary production of Br C also played an important role.The 120 hr backward air mass trajectories analysis and concentration-weighted trajectories analysis were also used to investigate potential sources of Br C in and around this area,which inferred most parts of Br C were derived from local emissions. | Wenyu Zhang Weigang Wang Jie Li Shuangliang Ma Chaofan Lian Kun Li Bo Shi Mingyuan Liu Yanyu Li QingQing Wang Yele Sun Shengrui Tong Maofa Ge | 2021 | Journal of Environmental Sciences2021，33，4： | 6 |
| 5 | Anti-scattering light focusing by fast wavefront shaping based on multi-pixel encoded digital-micromirror device显示文摘Speed and enhancement are the two most important metrics for anti-scattering light focusing by wavefront shaping(WS),which requires a spatial light modulator with a large number of modulation modes and a fast speed of response.Among the commercial modulators,the digital-micromirror device(DMD)is the sole solution providing millions of modulation modes and a pattern rate higher than 20 kHz.Thus,it has the potential to accelerate the process of anti-scattering light focusing with a high enhancement.Nevertheless,modulating light in a binary mode by the DMD restricts both the speed and enhancement seriously.Here,we propose a multi-pixel encoded DMD-based WS method by combining multiple micromirrors into a single modulation unit to overcome the drawbacks of binary modulation.In addition,to efficiently optimize the wavefront,we adopted separable natural evolution strategies(SNES),which could carry out a global search against a noisy environment.Compared with the state-of-the-art DMD-based WS method,the proposed method increased the speed of optimization and enhancement of focus by a factor of 179 and 16,respectively.In our demonstration,we achieved 10 foci with homogeneous brightness at a high speed and formed W-and S-shape patterns against the scattering medium.The experimental results suggest that the proposed method will pave a new avenue for WS in the applications of biomedical imaging,photon therapy,optogenetics,dynamic holographic display,etc. | Jiamiao Yang Qiaozhi He Linxian Liu Yuan Qu Rongjun Shao Bowen Song Yanyu Zhao | 2021 | Light(Science & Applications)2021，10，8： | 4 |
| 6 | Efficacy of water fraction from Dioscorea cirrhosa on oxidative stress and apoptosis in H9c2 cardiomyocytes induced by H2O2显示文摘OBJECTIVE:To investigate the efficacy of water fraction from Dioscorea cirrhosa(WF)on oxidative damage and apoptosis of cardiomyocytes induced by H2O2,and to study its mechanism.METHODS:Cell viability was measured by the MST assay kit.The content of malondialdehyde(MDA),release of lactate dehydrogenase(LDH)and activity of catalase(CAT)and superoxide dismutase(SOD)were detected by biochemical kit.The content of reactive oxygen species(ROS)was assessed by nonfluorescent probe 2′,7′-dichlorofluorescin diacetate(DCFH-DA).JC-1 was used to analyze the mitochondrial membrane potential(mtΔΨ)and Annexin-V-FITC/PI staining was applied to assess apoptosis of H9c2 by flow cytometry.Moreover,the expression of B-cell lymphoma-2(Bcl-2),Bcl-2-associated X(Bax),caspase-3,caspase-9,cleaved-caspase-3 and cleaved-caspase-9 proteins was determined by western blot analysis.RESULTS:WF increased cell viability and decreased LDH leakage in H9c2 cells exposed to H2O2.WF treatment decreased ROS and MDA level,enhanced SOD and CAT activities,improved mtΔΨand inhibited apoptosis.Western blot analysis demonstrated that the ratio of Bcl-2/Bax was increased and the expression cleaved-caspase-3,caspase-3,cleaved-caspase-9 and caspase-9 were decreased in group treated with WF.CONCLUSION:WF protects H9c2 myocardial cells on H2O2-induced oxidative stress and apoptosis by scavenging ROS,improving antioxidant capacity,protecting mitochondrial and regulating the proteins expression related to apoptosis. | LIU Chunhua PAN Jie WANG Aimin LAN Yanyu LI Yongjun LU Yuan SUN Jia WANG Yonglin LIU Ting LU Dingyan YOU Jingrui | 2021 | Journal of Traditional Chinese Medicine2021，41，1： | 4 |
| 7 | Multidrug-resistant Proteus mirabilis isolates carrying blaOXA-1 and blaNDM-1 from wildlife in China:increasing public health risk显示文摘The emergence of multidrug resistance(MDR)in Proteus mirabilis clinical isolates is a growing public health concern and has serious implications for wildlife.What is the role of wildlife has been become one of the hot issues in disseminating antimicrobial resistance.Here,54 P.mirabilis isolates from 12 different species were identified.Among them,25 isolates were determined to be MDR by profile of antimicrobial susceptibility;10 MDR P.mirabilis isolates were subjected to comparative genomic analysis by whole genome sequencing.Comprehensive analysis showed that chromosome of P.mirabilis isolates mainly carries multidrug-resistance complex elements harboring resistance to carbapenem genes blaOXA-1,blaNDM-1,and blaTEM-1.Class I integron is the insertion hotspot of IS26;it can be inserted into type I integron at different sites,thus forming a variety of multiple drug resistance decision sites.At the same time,Tn21,Tn7,and SXT/R391 mobile elements cause widespread spread of these drug resistance genes.In conclusion,P.mirabilis isolates from wildlife showed higher resistance to commonly used clinic drugs comparing to those from human.Therefore,wild animals carrying MDR clinical isolates should be paid attention to by the public health. | Qian KANG Xue WANG Jianan ZHAO Zhihui LIU Fang JI Han CHANG Jianchun YANG Shijia HU Ting JIA Xiaojia WANG Jiagui TANG Guoying DONG Guocheng HU Jing WANG Yanyu ZHANG Jianhua QIN Chengmin WANG | 2021 | Integrative Zoology2021，16，6： | 4 |
| 8 | Therapeutic strategies of glioblastoma (GBM):The current advances in the molecular targets and bioactive small molecule compounds显示文摘Glioblastoma(GBM)is the most common aggressive malignant tumor in brain neuroepithelial tumors and remains incurable.A variety of treatment options are currently being explored to improve patient survival,including small molecule inhibitors,viral therapies,cancer vaccines,and monoclonal antibodies.Among them,the unique advantages of small molecule inhibitors have made them a focus of attention in the drug discovery of glioblastoma.Currently,the most used chemotherapeutic agents are small molecule inhibitors that target key dysregulated signaling pathways in glioblastoma,including receptor tyrosine kinase,PI3K/AKT/mTOR pathway,DNA damage response,TP53 and cell cycle inhibitors.This review analyzes the therapeutic benefit and clinical development of novel small molecule inhibitors discovered as promising anti-glioblastoma agents by the related targets of these major pathways.Meanwhile,the recent advances in temozolomide resistance and drug combination are also reviewed.In the last part,due to the constant clinical failure of targeted therapies,this paper reviewed the research progress of other therapeutic methods for glioblastoma,to provide patients and readers with a more comprehensive understanding of the treatment landscape of glioblastoma. | Hui Liu Weimin Qiu Tianyu Sun Lei Wang Chenxi Du Yanyu Hu Wenyuan Liu Feng Feng Yao Chen Haopeng Sun | 2022 | Acta Pharmaceutica Sinica B2022，12，4： | 3 |
| 9 | One-Pot Synthesis of Hierarchically Nanoporous SSZ-13 for Conversion of Methanol to Olefins显示文摘The main disadvantage of microporous SSZ-13 catalyst used in the methanol to olefins(MTO) process is its rapid deactivation due to its relatively low coke resistance. Meanwhile, the hierarchical zeolites usually exhibit improved catalytic stability thanks to their better mass transfer ability. Herein, the hierarchically nanoporous SSZ-13 zeolites were one-pot synthesized by using N,N,N-trimethyl-1-adamantanammonium hydroxide as a microporous structure directing agent and C_(18)H_(37) N^+(CH_3)_2 C_6H_(12) N^+(CH_3)_2 C_6 H_(13)(Br^-)_2(hereinafter abbreviated as C_(18-6-6) Br_2) as a mesoporogen. The hierarchically nanoporous SSZ-13 catalyst was characterized by XRD, N_2 physisorption, SEM, TEM, TG-DTG, ^(27) Al and ^(29) SiNMR spectroscopy and NH_3-TPD techniques. The results showed that the hierarchical SSZ-13 zeolite synthesized in the presence of the C_(18-6-6) Br_2 surfactant exhibits aggregates of primary nanocrystals and contains the well-developed mesopores and excellent acidity. Compared to its conventional counterpart, the hierarchical SSZ-13 zeolite has longer catalytic lifetime and higher selectivity for ethylene and propylene in the MTO reaction, which can be attributed to the synergistic effect of their good acidity and improved diffusion properties resulted from the hierarchical pore structure. | Li Yuping Wang Yanyue Zhang Yi Liu Rui Li Xiaofeng Dou Tao | 2017 | China Petroleum Processing & Petrochemical Technology2017，19，3： | 2 |
| 10 | Treated dentin matrix induces odontogenic differentiation of dental pulp stem cells via regulation of Wnt/β-catenin signaling显示文摘Treated dentin matrix(TDM)is an ideal scaffold material containing multiple extracellular matrix factors.The canonical Wnt signaling pathway is necessary for tooth regeneration.Thus,this study investigated whether the TDM can promote the odontogenic differentiation of human dental pulp stem cells(hDPSCs)and determined the potential role of Wnt/β-catenin signaling in this process.Different concentrations of TDM promoted the dental differentiation of the hDPSCs and meanwhile,the expression of GSK3βwas decreased.Of note,the expression of the Wnt/β-catenin pathway-related genes changed significantly in the context of TDM induction,as per RNA sequencing(RNA seq)data.In addition,the experiment showed that new dentin was visible in rat mandible cultured with TDM,and the thickness was significantly thicker than that of the control group.In addition,immunohistochemical staining showed lower GSK3βexpression in new dentin.Consistently,the GSK3βknockdown hDPSCs performed enhanced odotogenesis compared with the control groups.However,GSK3βoverexpressing could decrease odotogenesis of TDM-induced hDPSCs.These results were confirmed in immunodeficient mice and Wistar rats.These suggest that TDM promotes odontogenic differentiation of hDPSCs by directly targeting GSK3βand activating the canonical Wnt/β-catenin signaling pathway and provide a theoretical basis for tooth regeneration engineering. | Sirui Liu Jingjing Sun Shuai Yuan Yanyu Yang Yuping Gong Ying Wang Runying Guo Xue Zhang Yiming Liu Hongyan Mi Meiyue Wang Mengzhe Liu Rui Li | 2022 | Bioactive Materials2022，7，1： | 2 |
| 11 | Recent advances in Pb-Sn mixed perovskite solar cells显示文摘Organic-inorganic hybrid lead-tin perovskite solar cells(Pb-Sn PSCs)have attracted much attention because of their advantages of low toxicity,variable bandgap,and feasibility for all-perovskite tandem solar cells,and the current power conversion efficiency(PCE)has exceeded 23%.However,due to the rambunctious crystallization process,easily oxidized Sn(Ⅱ)and inadequate energy level arrangement,there are many defects in perovskite films resulting in serious carrier recombination,which makes PCE still lag Pb-based PSCs.The quality of perovskite films is an important factor affecting the overall device performance.The selection and optimization of transport layers not only determines the interface energy level arrangement but also affects the carrier transport.In this paper,the research progress in improving performance of Pb-Sn PSCs in recent years is reviewed from aspects of perovskite layer and transport layers.The profound understanding of different promotion methods is summarized as well.These results have certain guiding significance for the future development and commercial application of Pb-Sn PSCs. | Yanyu Deng Guanhua Ren Danao Han Wenbin Han Zhuowei Li Chunyu Liu Wenbin Guo | 2022 | Journal of Energy Chemistry2022，31，10： | 2 |
| 12 | Efficacy of seasonal pandemic influenza hemagglutinin DNA vaccines delivered by electroporation against aseasonal H1N1 virus challenge in mice显示文摘Prophylactic DNA vaccines against the influenza virus are promising alternatives to conventional vaccines.In this study,we generated two candidate gene-based influenza vaccines encoding either the seasonal or pandemic hemagglutinin antigen(HA) from the strains A/New Caledonia/20/99(H1N1)(pV1A5) and A/California/04/2009(H1N1)(pVEH1) ,respectively.After verifying antigen expression,the immunogenicity of the vaccines delivered intramuscularly with electroporation was tested in a mouse model.Sera of immunized animals were tested in hemagglutination inhibition assays and by ELISA for the presence of HA-specific antibodies.HA-specific T-cells were also measured in IFN-γELISpot assays.The protective efficacy of the candidate influenza vaccines was evaluated by measuring mortality rates and body weight after a challenge with 100 LD50 of mouse-adapted A/New Caledonia/20/99(H1N1) .Mice immunized with either one of the two vaccines showed significantly higher T cell and humoral immune responses(P<0.05) than the pVAX1 control group.Additionally,the pV1A5 vaccine effectively protected the mice against a lethal homologous mouse-adapted virus challenge with a survival rate of 100%compared with a 40%survival rate in the pVEH1 vaccinated group(P<0.05) .Our study indicates that the seasonal influenza DNA vaccine completely protects against the homologous A/New Caledonia/20/99 virus(H1N1) ,while the pandemic influenza DNA vaccine only partially protects against this virus. | TAN Lei LU HuiJun ZHANG Dan WANG KaiYan TIAN MingYao LIU CunXia LIU YanYu HU Bo JIN NingYi | 2011 | Science China(Life Sciences)2011，54，4： | 2 |
| 13 | Cetus:an efficient symmetric searchable encryption against file-injection attack with SGX显示文摘Symmetric searchable encryption(SSE)allows the users to store and query their private data in the encrypted database.Many SSE schemes for different scenarios have been proposed in the past few years,however,most of these schemes still face more or fewer security issues.Using these security leakages,many attacks against the SSE scheme have been proposed,and especially the non-adaptive file injection attack is the most serious.Non-adaptive file injection attack(NAFA)can effectively recover some extremely important private information such as keyword plaintext.As of now,there is no scheme that can effectively defend against such attacks.We first propose the new security attribute called toward privacy to resist nonadaptive file injection attacks.We then present an efficient SSE construction called Cetus to achieve toward privacy.By setting up a buffer and designing the efficient oblivious reading algorithm based on software guard extensions(SGX),we propose the efficient one-time oblivious writing mechanism.Oblivious writing protects the update pattern and allows search operations to be performed directly on the data.The experiment results show that Cetus achieves O(aw)search time and O(1)update communication.The practical search time,communication,and computation overheads incurred by Cetus are lower than those of state-of-the-art. | Yanyu HUANG Siyi LV Zheli LIU Xiangfu SONG Jin LI Yali YUAN Changyu Dong | 2021 | Science China(Information Sciences)2021，64，8： | 2 |
| 14 | Evaluation and Evolution of MAX-DOAS-observed Vertical NO_(2) Profiles in Urban Beijing显示文摘Multiaxis differential absorption spectroscopy(MAX-DOAS)is a newly developed advanced vertical profile detection method,but the vertical nitrogen dioxide(NO_(2))profiles measured by MAX-DOAS have not yet been fully verified.In this study,we perform MAX-DOAS and tower gradient observations to simultaneously acquire tropospheric NO_(2)observations in the Beijing urban area from 1 April to 31 May 2019.The average values of the tropospheric NO_(2)vertical column densities measured by MAX-DOAS and the tropospheric monitoring instrument are 15.8×1015 and 12.4×1015 molecules cm−2,respectively,and the correlation coefficient R reaches 0.87.The MAX-DOAS measurements are highly consistent with the tower-based in situ measurements,and the correlation coefficients R from the ground to the upper air are 0.89(60 m),0.87(160 m),and 0.76(280 m).MAX-DOAS accurately measures the trend of NO_(2)vertical profile changes,although a large underestimation occurs by a factor of two.By analyzing the NO_(2)vertical profile,the NO_(2)concentration reveals an exponential decrease with height.The NO_(2)vertical profile also coincides with the evolution of the boundary layer height.The study shows that the NO_(2)over Beijing mainly originates from local sources and occurs in the boundary layer,and its vertical evolution pattern has an important guiding significance to better understand nitrate production and ozone pollution. | Yanyu KANG Guiqian TANG Qihua LI Baoxian LIU Jianfeng CAO Qihou HU Yuesi WANG | 2021 | Advances in Atmospheric Sciences2021，38，7： | 2 |
| 15 | Cryo-EM structure of the inner ring from the Xenopus laevis nuclear pore complex显示文摘Nuclear pore complex(NPC)mediates nucleocytoplasmic shuttling.Here we present single-particle cryo-electron microscopy structure of the inner ring(IR)subunit from the Xenopus laevis NPC at an average resolution of 4.2Å.A homo-dimer of Nup205 resides at the center of the IR subunit,flanked by two molecules of Nup188.Four molecules of Nup93 each places an extended helix into the axial groove of Nup205 or Nup188,together constituting the central scaffold.The channel nucleoporin hetero-trimer of Nup62/58/54 is anchored on the central scaffold.Six Nup155 molecules interact with the central scaffold and together with the NDC1–ALADIN hetero-dimers anchor the IR subunit to the nuclear envelope and to outer rings.The scarce inter-subunit contacts may allow sufficient latitude in conformation and diameter of the IR.Our structure reveals the molecular basis for the IR subunit assembly of a vertebrate NPC. | Gaoxingyu Huang Xiechao Zhan Chao Zeng Ke Liang Xuechen Zhu Yanyu Zhao Pan Wang Qifan Wang Qiang Zhou Qinghua Tao Minhao Liu Jianlin Lei Chuangye Yan Yigong Shi | 2022 | Cell Research2022，32，5： | 1 |
| 16 | Towards realistic assessment of cultivated land quality in an ecologically fragile environment: A satellite imagery-based approach显示文摘 | Yansui Liu Yanyu Zhang Liying Guo | 2009 | Applied Geography2009，，2： | 1 |
| 17 | Towards realistic assessment of cultivated land quality in an ecologically fragile environment: A satellite imagery - based approach 显示文摘 | Liu Yansui Zhang Yanyu Guo Liying | 2010 | Applied Geography2010，30，： | 1 |
| 18 | Circadian effects on outcome following surgery for intracerebral hemorrhage in humans?显示文摘 | Junwen Guan Yuanlin Ding Yanyu Liu Yonghong Li Yanyou Liu Zhengrong Wang | 2008 | Brain Research2008，，： | 1 |
| 19 | Exploring the Anthropogenic Driving Forces of China's Provincial Environmental Impacts显示文摘 | Wang Mingquan Song Yanyu Liu Jingshuang | 2012 | International Journal of Sustainable Development and World Ecology2012，19，5： | 1 |
| 20 | Molecular diversity and biogeography of benthic microeukaryotes in temperate seagrass(Zostera japonica)systems of northern China显示文摘The productivity and health of seagrass depend on the combined inputs of nutrients from the water and sediments in which they grow and the microbiota with which they live intimately.However,little is known about the composition and diversity pattern of single-celled benthic eukaryotes in seagrass meadows.Here,we investigated how the structure and diversity of the benthic microeukaryotic community vary with respect to season,location,and seagrass colonization,by applying 18S rRNA gene amplicon sequencing for 96 surface sediment samples that were collected from three different seagrass habitats through four seasons.We found that benthic microeukaryotic communities associated with seagrass Zostera japonica exhibited remarkable spatial and seasonal variations,as well as differences between vegetated and unvegetated sediments.Diatoms and dinoflagellates predominated in the benthic microeukaryotic communities,but they were inversely correlated and displaced each other as the dominant microbial group in different seasons or habitats.Mucoromycota was more prevalent in vegetated sediments,whereas Lobulomycetales and Chytridiales had higher proportions in unvegetated sites.Total organic carbon and total organic nitrogen were the most important environmental factors in driving the microeukaryotic assemblages and diversity.Our study expands the available knowledge on the biogeographic distribution patterns and niche preferences for benthic microeukaryotes in seagrass systems. | Pengyuan Liu Haikun Zhang Yanyu Sun Caixia Wang Xiaoke Hu | 2022 | Acta Oceanologica Sinica2022，41，11： | 1 |
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