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| 1 | Acetylenes and fatty acids from Codonopsis pilosula显示文摘Four new acetylenes(1–4) and one new unsaturated ω-hydroxy fatty acid(5),together with 5known analogues,were isolated from an aqueous extract of Codonopsis pilosula roots.Their structures were determined by spectroscopic and chemical methods.The new acetylenes are categorized as an unusual cyclotetradecatrienynone(1),tetradecenynetriol(2),and rare octenynoic acids(3 and 4),respectively,and 3 and 4 are possibly derived from oxidative metabolic degradation of 1 and/or 2.The absolute configuration of 1 was assigned by comparison of the experimental circular dichroism(CD)spectrum with the calculated electronic circular dichroism(ECD) spectra of stereoisomers based on the quantum-mechanical time-dependent density functional theory,while the configuration of 2 was assigned by using modified Mosher's method based on the MPA determination rule of ΔδRSvalues for diols. | Yueping Jiang Yufeng Liu Qinglan Guo Zhibo Jiang Chengbo Xu Chenggen Zhu Yongchun Yang Sheng Lin Jiangong Shi | 2015 | Acta Pharmaceutica Sinica B2015，5，3： | 15 |
| 2 | Nonlinear optical properties of graphene-based materials显示文摘Graphene,a two-dimensional carbon atom sheet,has attracted tremendous attention and research interest because of its exceptional physical properties.Graphene has high mobility and optical transparency,in addition to flexibility,robustness and environmental stability.The main focus so far has been on fundamental physics and electronic devices.However,because the linear dispersion of the Dirac electrons enables ultrawideband tunability,we believe its true potential lies in photonics and optoelectronics.In this review,we introduce recent advances in the nonlinear optical properties of graphene-based materials.The rise of graphene in nonlinear optics is shown by several recent results,ranging from saturable absorbers and the four-wave mixing effect to giant two-photon absorption,reverse saturable absorption and optical limiting.The relevant forms of the graphene-based materials include pure graphene,graphene oxide and graphene hybrids. | LIU ZhiBo ZHANG XiaoLiang YAN XiaoQing CHEN YongSheng TIAN JianGuo | 2012 | Chinese Science Bulletin2012，57，23： | 10 |
| 3 | Relationship between the Flow Blockage of Tip Leakage Vortex and its Evolutionary Procedures inside the Rotor Passage of a Subsonic Axial Compressor显示文摘The near casing flow fields inside the rotor passage of a 1.5 stage axial compressor with different blade-loading levels and tip gap sizes were measured by using stereoscopic particle image velocimetry(SPIV). Based on a carefully defined blockage extracting method, the variations of blockage parameter inside the blade passage were analyzed. It was found that the variation of blockage parameter appeared as a non-monotonic behavior inside the blade passage in most cases. This non-monotonic behavior became much more remarkable as the blade loading increases or mass flow rate decreases.The variations of the blockage parameter inside the blade passage had close relation to the evolutionary procedures of the tip leakage vortex(TLV). The destabilization of the TLV caused a rapid increasing of the blockage parameter. After the TLV lost the features of a concentrated streamwise vortex,the blockage parameter usually got a peak value. And then, because of the intense turbulent mixing between the TLV low momentum flow and its surrounding flows, the flow deficit inside the TLV recovered. | DU Hui YU Xianjun ZHANG Zhibo LIU Baojie | 2013 | Journal of Thermal Science2013，22，6： | 7 |
| 4 | Multimode Interference Refractive Index Sensor Based on Coreless Fiber显示文摘multimode 干扰折射索引(RI ) 传感器数字地并且试验性地基于无核心的纤维被表明。二相同单个模式纤维(SMF ) 在什么时候的能被看作微弱地与步索引侧面指导 multimode 纤维(MMF ) 的等价物的无核心的纤维的节的两结束被拼接包围折射索引(SRI ) 比无核心的纤维的低。因此,它成为常规单个模式的 multimode 单个模式(SMS ) 纤维结构但是与一种更大的核心尺寸。产量系列将由于无核心的纤维的直接暴露在 SRI 与变化一起变。在不同 SRI 下面的产量系列数字地被学习,以及有无核心的纤维的不同长度和直径的敏感。断言和计算与试验性的结果显示出好协议。证明由确认可行的建议 RI 传感器试验,并且相对错误仅仅是 0.1% 哪个占据了更好的察觉到的性能和有实行可能。 | Yang Li Zhibo Liu Shuisheng Jian | 2014 | Photonic Sensors2014，4，1： | 4 |
| 5 | Apatite Fission Track Ages in the Duolong Ore District and the Uplift Time of the Qiangtang Terrrane, Tibet显示文摘Objective Fission track(FT)analysis has developed into one of the most useful techniques throughout the geologic community to reconstruct low-temperature thermal historyof rocks over geological time(Reiners et al.,2005).The FT method is based on the accumulation of narrow damage trails(i.e.,fission tracks)in uranium-rich mineral grains(e.g.,apatite,zircon,titanite)and natural glasses, | YANG Huanhuan TANG Juxing SONG Yang LIU Zhibo LIN Bin | 2018 | Acta Geologica Sinica(English Edition)2018，92，1： | 4 |
| 6 | Typing of biliary tumor thrombus influences the prognoses of patients with hepatocellular carcinoma显示文摘Objective:To establish a new classification of biliary tumor thrombus(BTT).Methods:Overall survival of patients with BTT was first used to determine whether it correlated with current hepatocellular carcinoma staging systems.Univariate and multivariate analyses were used to determine factors affecting the overall survival(OS)to form the basis of our new classification for BTT.Results:All 6 international staging systems showed overlapping survival curves.Univariate followed by multivariate analyses showed that total bilirubin and intrahepatic/extrahepatic BTT were significant risk factors of OS.Based on these data,a new BTT classification was defined as:TypeⅠ:intrahepatic BTT;and TypeⅡ:extrahepatic BTT involving a common bile duct or common hepatic duct.TypeⅠwas further subdivided into type Ia:BTT involving a second-order intrahepatic duct or above,and type Ib:BTT involving a first-order intrahepatic duct.TypeⅡwas further subdivided into typeⅡa and typeⅡb using a cut-off total bilirubin(TB)>300μmol/L.The numbers(percentages)of patients with typesⅠandⅡBTT were 69(34.2%)and 133(65.8%),respectively.The median OS of typeⅠpatients was significantly higher than that of typeⅡpatients(37.5 months vs.23.2 months;P=0.002).Using subgroup analyses,OS outcomes were significantly different between the subgroups of typeⅡb and type IIa,although there was no significant difference between the type Ia and type Ib subgroups(P=0.07).Conclusions:A new BTT classification was established to predict prognoses of HCC patients with BTT who underwent liver resection. | Juxian Sun Jiayi Wu Chang Liu Jie Shi Yonggang Wei Jianyin Zhou Zhibo Zhang Wan Yee Lau Maolin Yan Shuqun Cheng | 2021 | Cancer Biology & Medicine2021，18，3： | 3 |
| 7 | Numerical study on dynamic mechanism of brain volume and shear deformation under blast loading显示文摘Blast-induced traumatic brain injury(b-TBI)is a kind of significant injury to soldiers in the current military conflicts.However,the mechanism of b-TBI has not been well understood,and even there are some contradictory conclusions.It is crucial to reveal the dynamic mechanism of brain volume and shear deformations under blast loading for better understanding of b-TBI.In this paper,the numerical simulation method is adopted to carry out comprehensive and in-depth researches on this issue for the first time.Based on the coupled Eulerian-Lagrangian method,the fluid-structure coupling model of the blast wave and human head is developed to simulate two situations,namely the head subjected to the frontal and lateral impacts.The simulation results are analyzed to obtain the underlying dynamic mechanisms of brain deformation.The brain volume deformation is dominated by the local bending vibration of the skull,and the corresponding frequency for the forehead skull under the frontal impact and the lateral skull faced to the lateral impact is as high as 8 kHz and 5 kHz,respectively.This leads to the high-frequency fluctuation of brain pressure and the large pressure gradient along the skull,totally different from the dynamic response of brain under head collisions.While the brain shear deformation mainly depends on the relative tangential displacement between the skull and brain and the anatomical structure of inner skull,being not related to the brain pressure and its gradient.By further comparing the medical statistics,it is inferred that diffuse axonal injury and brain contusion,the two most common types of b-TBI,are mainly attributed to brain shear deformations.And the von Mises stress can be adopted as the indicator for these two brain injuries.This study can provide theoretical guidance for the diagnosis of b-TBI and the development of protective equipment. | Zhijie Li Zhibo Du Xiaochuan You Zhanli Liu Jian Cheng Chengcheng Luo Dongyang Chu Shaowu Ning Yue Kang Ce Yang Zhuo Zhuang | 2019 | Acta Mechanica Sinica2019，35，5： | 3 |
| 8 | Solution-processable graphene mesh transparent electrodes for organic solar cells显示文摘有好电导率和透明性的 Graphene 网孔电极(GME ) 被标准工业影印石版术和 O2 血浆蚀刻过程用 graphene 答案制作了。器官光电( OPV )用 GME 的房间作为有poly-( 3-hexylthiophene )的混合的透明电极, /phenyl-C61-butyric 酸甲基酉旨( P3HT/PC61BM )作为活跃的层被制作了并且展出2.04%的力量变换效率( PCE ),为透明基于电极的太阳能电池迄今为止报导了的处理答案的 graphene 的最高的 PCE 。 | Qian Zhang Xiangjian Wan Fei Xing Lu Huang Guankui Long Ningbo Yi Wang Ni Zhibo Liu Jianguo Tian Yongsheng Chen | 2013 | Nano Research2013，6，7： | 3 |
| 9 | CRISPR/Cas9-mediated mutagenesis at microhomologous regions of human mitochondrial genome显示文摘Genetic manipulation of mitochondrial DNA(mtDNA)could be harnessed for deciphering the gene function of mitochondria;it also acts as a promising approach for the therapeutic correction of pathogenic mutation in mtDNA.However,there is still a lack of direct evidence showing the edited mutagenesis within human mtDNA by clustered regularly interspaced short palindromic repeats-associated protein 9(CRISPR/Cas9).Here,using engineered CRISPR/Cas9,we observed numerous insertion/deletion(InDel)events at several mtDNA microhomologous regions,which were triggered specifically by double-strand break(DSB)lesions within mtDNA.InDel mutagenesis was significantly improved by sgRNA multiplexing and a DSB repair inhibitor,iniparib,demonstrating the evidence of rewiring DSB repair status to manipulate mtDNA using CRISPR/Cas9.These findings would provide novel insights into mtDNA mutagenesis and mitochondrial gene therapy for diseases involving pathogenic mtDNA. | Bang Wang Xiujuan Lv Yufei Wang Zhibo Wang Qi Liu Bin Lu Yong Liu Feng Gu | 2021 | Science China(Life Sciences)2021，64，9： | 3 |
| 10 | New Zircon U-Pb Age of the Ore-bearing Porphyry from the Kuga Copper Deposit in the Eastern Bangongco–Nujiang Matallogenic Belt, Tibet显示文摘Objective As the third most important copper polymetallic metallogenic belt in Tibet,the Bangongco–Nujiang metallogenic belt(BNMB)has attracted much attention among geoscientists all over the world(Lin Bin et al.,2017a).There are two ore clusters in the western of BNMB,the Duolong giant porphyry-epithermal Cu(Au,Ag)ore cluster and the Ga’erqiong–Galalelarge porphyry- | LIN Bin SONG Yang LIU Zhibo LIU Zhenyu GAO Yiming | 2018 | Acta Geologica Sinica(English Edition)2018，92，2： | 3 |
| 11 | Fiscal Expenditure and Income Gap between Urban and Rural Residents: An Empirical Study Based on Malmquist Index and Spatial Econometrics显示文摘Based on the analysis methods of non-parametric Malmquist index and spatial econometrics as well as the provincial panel data in 2007-2010, this paper estimates the efficiency of fiscal expenditure from local governments in china in terms of reducing the income gap between urban and rural residents for the first time and evaluates the spatial correlation and heterogeneity of this efficiency. The results have shown that the fiscal expenditure of most provinces is of low efficiency in reducing the income gap between urban and rural residents, and the expenditure efficiency of local governments is not relevant to their levels of economic development. Besides, the efficiency on reducing the urban-rural income gap between different regions of China has a tendency of convergence. But this is mainly reflected inside the regional economic belt. There is significant difference between the efficiency of each economic belt. The central region has the highest efficiency in a rising trend, the western region has the lowest efficiency in a downward trend, while the eastern region is relatively stable. | Jianhui LIU Ming ZHANG Fangfang ZHANG Zhibo ZHOU | 2013 | Asian Agricultural Research2013，5，2： | 2 |
| 12 | Therapeutic Effect of Human Umbilical Cord Multipotent Mesenchymal Stromal Cells in a Rat Model of Stroke显示文摘 | Wenbin Liao Jiang Xie Jian Zhong Yongjun Liu Lei Du Bin Zhou Jie Xu Pengxia Liu Shaoguang Yang Jiming Wang Zhibo Han Zhong Chao Han | 2009 | Transplantation2009，，3： | 2 |
| 13 | Synthesis, characterization and optical limiting property of covalently oligothiophene-functionalized graphene material显示文摘 | Yongsheng Liu Jiaoyan Zhou Xiaoliang Zhang Zhibo Liu Xiangjian Wan Jianguo Tian Tuo Wang Yongsheng Chen | 2009 | Carbon2009，，13： | 2 |
| 14 | The Entire Small Intestine Mediates the Changes in Glucose Homeostasis After Intestinal Surgery in Goto-Kakizaki Rats显示文摘 | Shaozhuang Liu Guangyong Zhang Lei Wang Dong Sun Weijie Chen Zhibo Yan Yu Sun Sanyuan Hu | 2012 | Annals of Surgery2012，，6： | 2 |
| 15 | Use of angiotensin-converting enzyme inhibitors and angiotensin Ⅱ receptor blockers in context of COVID-19 outbreak:a retrospective analysis显示文摘The possible effects of angiotensin-converting enzyme inhibitors(ACEIs)or angiotensin Ⅱ receptor blockers(ARBs)on COVID-19 disease severity have generated considerable debate.We performed a single-center,retrospective analysis of hospitalized adult COVID-19 patients in Wuhan,China,who had definite clinical outcome(dead or discharged)by February 15,2020.Patients on anti-hypertensive treatment with or without ACEI/ARB were compared on their clinical characteristics and outcomes.The medical records from 702 patients were screened.Among the 101 patients with a history of hypertension and taking at least one anti-hypertensive medication,40 patients were receiving ACEI/ARB as part of their regimen,and 61 patients were on antihypertensive medication other than ACEI/ARB.We observed no statistically significant differences in percentages of in-hospital mortality(28%vs.34%,P=0.46),ICU admission(20%vs.28%,P=0.37)or invasive mechanical ventilation(18%vs.26%,P=0.31)between patients with or without ACEI/ARB treatment.Further multivariable adjustment of age and gender did not provide evidence for a significant association between ACEI/ARB treatment and severe COVID-19 outcomes.Our findings confirm the lack of an association between chronic receipt of reninangiotensin system antagonists and severe outcomes of COVID-19.Patients should continue previous antihypertensive therapy until further evidence is available. | Jiuyang Xu Chaolin Huang Guohui Fan Zhibo Liu Lianhan Shang Fei Zhou Yeming Wang Jiapei Yu Luning Yang Ke Xie Zhisheng Huang Lixue Huang Xiaoying Gu Hui Li Yi Zhang Yimin Wang Frederick G.Hayden Peter W.Horby Bin Cao Chen Wang | 2020 | Frontiers of Medicine2020，14，5： | 2 |
| 16 | Duodenal-jejunal bypass surgery on type 2 diabetic rats reduces the expression of matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-1 in the thoracic aorta显示文摘 | Maimaitiyusufu Wubulikasimu Han Haifeng Yan Zhibo Zhang Xiang Liu Shaozhuang Zhang Guangyong Kasimu Aimaiti Hu Sanyuan | 2014 | Chinese Medical Journal2014，，13： | 2 |
| 17 | Clinical factors associated with composition of lung microbiota and important taxa predicting clinical prognosis in patients with severe community-acquired pneumonia显示文摘Few studies have described the key features and prognostic roles of lung microbiota in patients with severe community-acquired pneumonia(SCAP).We prospectively enrolled consecutive SCAP patients admitted to ICU.Bronchoscopy was performed at bedside within 48 h of ICU admission,and 16S rRNA gene sequencing was applied to the collected bronchoalveolar lavage fluid.The primary outcome was clinical improvements defined as a decrease of 2 categories and above on a 7-category ordinal scale within 14 days following bronchoscopy.Sixty-seven patients were included.Multivariable permutational multivariate analysis of variance found that positive bacteria lab test results had the strongest independent association with lung microbiota(R2=0.033;P=0.018),followed by acute kidney injury(AKI;R2=0.032;P=0.011)and plasma MIP-1βlevel(R2=0.027;P=0.044).Random forest identified that the families Prevotellaceae,Moraxellaceae,and Staphylococcaceae were the biomarkers related to the positive bacteria lab test results.Multivariable Cox regression showed that the increase inα-diversity and the abundance of the families Prevotellaceae and Actinomycetaceae were associated with clinical improvements.The positive bacteria lab test results,AKI,and plasma MIP-1βlevel were associated with patients’lung microbiota composition on ICU admission.The families Prevotellaceae and Actinomycetaceae on admission predicted clinical improvements. | Sisi Du Xiaojing Wu Binbin Li Yimin Wang Lianhan Shang Xu Huang Yudi Xia Donghao Yu Naicong Lu Zhibo Liu Chunlei Wang Xinmeng Liu Zhujia Xiong Xiaohui Zou Binghuai Lu Yingmei Liu Qingyuan Zhan Bin Cao | 2022 | Frontiers of Medicine2022，16，3： | 2 |
| 18 | Petrogenesis and Tectonic Significance of the Three-Period Porphyries from the Daruoluolong Cu(Au) Deposit, Tibet, China显示文摘The Daruoluolong deposit is the first high-grade Cu(Au) deposit discovered in the middle section of theBangonghu-Nujiang (herein after referred to as Ban-Nu)metallogenic belt, which has not been documented aboutpreviously. This deposit is located in Shuanghu County ofnorthern Tibet, and its geotectonic position belongs to thenorthern margin of the Ban-Nu suture and southern marginof the Qiangtang terrane. There are three-periodporphyries including ore-bearing granodiorite porphyry,barren granite porphyry and biotite granodiorite porphyryin the deposit. In this paper, we present new zircon U-Pbdate, petrogeochemistry, and Hf isotopic compositions toassess host rock and mineralization age, rock type andmagma source. We have also discussed the metallogenicbackground of the Daruoluolong deposit which isconsistent with that of Naruo the deposit in the westernsection of the Ban-Nu metallogenic belt (Ding Shuai et al.,2017). | GAO Ke SONG Yang LIU Zhibo FANG Xiang LI Faqiao LI Haifeng | 2018 | Acta Geologica Sinica(English Edition)2018，92，3： | 2 |
| 19 | Stretchable and self-healable hydrogel artificial skin显示文摘Hydrogels have emerged as promising materials for the construction of skin-like mechanical sensors.The common design of hydrogel-based artificial skin requires a dielectric sandwiched between two hydrogel layers for capacitive sensing.However,such a planar configuration limits the sensitivity,stretchability and self-healing properties.Here,we report the design of single-layer composite hydrogels with bulk capacitive junctions as mechanical sensors.We engineer dielectric peptide-coated graphene(PCG)to serve as homogenously dispersed electric double layers in hydrogels.Any mechanical motions that alter the microscopic distributions of PCG in the hydrogels can significantly change the overall capacitance.We use peptide self-assembly to render strong yet dynamic interfacial interactions between the hydrogel network and graphene.The resulting hydrogels can be stretched up to 77 times their original length and self-heal in a few minutes.The devices can effectively sense strain and pressure in both air and aqueous environments,providing tremendous opportunities for next-generation iontronics. | Bin Xue Hui Sheng Yongqiang Li Lan Li Weishuai Di Zhengyu Xu Linjie Ma Xin Wang Haoting Jiang Meng Qin Zhibo Yan Qing Jiang Jun-Ming Liu Wei Wang Yi Cao | 2022 | National Science Review2022，9，7： | 2 |
| 20 | A graphene hybrid material covalently functionalized with porphyrin: synthe- sis and optical limiting property显示文摘 | XU YANFEI LIU ZHIBO ZHANG XIAOLI | 2009 | Advanced Materials2009，21，12： | 1 |
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