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| 1 | Pharmacogenetic Correlates of Antipsychotic-Induced Weight Gain in the Chinese Population显示文摘Antipsychotic-induced weight gain(AIWG) is a common adverse effect of this treatment, particularly with second-generation antipsychotics, and it is a major health problem around the world. We aimed to review the progress of pharmacogenetic studies on AIWG in the Chinese population to compare the results for Chinese with other ethnic populations, identify the limitations and problems of current studies, and provide future research directions in China. Both English and Chinese electronic databases were searched to identify eligible studies. We determined that [ 25 single-nucleotide polymorphisms in19 genes have been investigated in association with AIWG in Chinese patients over the past few decades. HTR2 C rs3813929 is the most frequently studied single-nucleotide polymorphism, and it seems to be the most strongly associated with AIWG in the Chinese population. However, many genes that have been reported to be associated with AIWG in other ethnic populations have not beenincluded in Chinese studies. To explain the pharmacogenetic reasons for AIWG in the Chinese population,genome-wide association studies and multiple-center, standard, unified, and large samples are needed. | Chao Luo Junyan Liu Xu Wang Xiaoyuan Mao Honghao Zhou Zhaoqian Liu | 2019 | Neuroscience Bulletin2019，35，3： | 7 |
| 2 | Highly-ordered dye-sensitized TiO_2 nanotube arrays film used for improving photoelectrochemical electrodes显示文摘Thin titanium oxide nanotube arrays (TNAs) films were synthesized by anodization of titanium foil in an aqueous dimethyl sulfoxide solution using a platinum foil counter electrode.TNAs up to 6.8 μm in length,120 nm in inner pore diameter,and 20 nm in wall thickness were obtained by 40 V potentials anodization for 24 h.Their microstructures and surface morphologies were characterized by XRD,TEM,SAED and UV-vis spectroscopy.The photoelectrochemical properties of as-prepared unsensitized and dye-sensitized TNAs electrodes were examined under simulated solar light (AM 1.5,100 mW/cm2) illumination.The results showed that the photocurrent of the dye-sensitized TNAs electrodes reached 6.9 mA/cm2,which was 6 times more than that of the dye-sensitized TiO2 nanoparticles (TNPs) electrodes.It implied that the electron transport process and the charge recombination suppression within TNAs electrodes were much more favorable in comparison with that in the TNPs electrodes.Electrodes applying such kind of titania nanotubes will have a potential to further enhance the efficiencies of TNAs-based dye-sensitized solar cells. | XIONG BiTao WANG ChangRong LUO JunYan CHEN BaoXin ZHOU BaoXue ZHU ZhiYan | 2013 | Science China Chemistry2013，56，1： | 3 |
| 3 | Interplay between the cellular autophagy machinery and positive-stranded RNA viruses显示文摘Autophagy 是在维持细胞的动态平衡充当一个关键管理者的一个保存细胞的过程。最近的研究含有为在由搬迁入侵病原体并且通过 modulating 的感染和免疫的 autophagy 的一个重要角色天生、适应的有免疫力的回答。然而,几病原体,一些尤其是积极海滨的 RNA 病毒,破坏了 autophagy 到他们的自己的目的。在这评论,我们总结有一个积极海滨的 RNA 染色体的病毒怎么与主人 autophagy 机械交往控制他们的复制并且传播的当前的理解。我们考察位于 autophagy 的正式就职下面的机制并且讨论支持 viral 和 autophagy 和包含的潜在的机制的抗病毒的功能。 | Junyan Shi Honglin Luo | 2012 | Acta Biochimica et Biophysica Sinica2012，44，5： | 2 |
| 4 | Morphology,Chemistry and U-Pb Geochronology of Zircon Grains in Quartz Monzodiorite from the Sunzhuang Area,Fanshi County,Shanxi Province显示文摘The morphology, REE geochemistry and U-Pb geochronology of zircons from quartz monzodiorite in the Sunzhuang area, Fanshi County, Shanxi Province are presented in this study. The zircon crystals can be classified into four main types as: AB, L, S and P, and 24 subtypes such as AB4, AB5, L5, and S3. The maximum crystallization temperature of zircon was estimated as 850°C, with the minimum of 550°C. The peak temperatures of the zircon crystallization range from 650°C to 700°C. The abundances of Th and U in the zircon grains show large variation with the Th/U values > 0.4. The Th and U values also show a positive correlation in most zircons. The REE abundance of zircon in the quartz monzodiorite ranges from 280.4 ppm to 2143 ppm with an average of 856.4 ppm. The chondrite normalized zircon REE patterns show two types, one is characterized by HREE enrichment and LREE depletion with positive Ce-anomaly and negative Eu-anomaly whereas the other is HREE enriched and LREE depleted with negative Eu-anomaly but without positive Ce-anomaly, and relatively flat patterns. The LA-ICP-MS U-Pb geochronology on the zircons yields a mean age of 133±0.87 Ma. Our data on zircon morphology, composition and U-Pb geochronology reveal that the parent magma of the quartz monzodiorite which was emplaced during late Yanshanian had a mixed crust-mantle source, with crustal components dominating. The magma is inferred to have been water rich and alkaline with initial high oxygen fugacity. Post-magmatic hydrothermal activity occurred under relatively reducing conditions which was conductive for gold precipitation in the Yixingzhai gold deposit. | SONG Jiye LI Shengrong QIN Mingkuan CAI Yuqi LUO Junyan ZHANG Juquan LI Chenglu SANTOSH M. | 2015 | Acta Geologica Sinica(English Edition)2015，89，4： | 2 |
| 5 | Understanding enzyme catalysis by means of supramolecular artificial enzymes显示文摘Enzymes are biomacromolecules responsible for the abundant chemical biotransformations that sustain life. Recently, biochemists have discovered that multiple conformations and numerous parallel paths are involved during the processes catalyzed by enzymes. It is plausible that the entire macromolecular scaffold is involved in catalysis via cooperative motions that result in incredible catalytic efficiency. Moreover, some enzymes can very strongly bind the transition state with an association constant of up to 1024 M-1, suggesting that covalent bond formation is a possible process during the conversion of the transition state in enzyme catalysis, in addition to the concatenation of noncovalent interactions. Supramolecular chemistry provides fundamental knowledge about the relationships between the dynamic structures and functions of organized molecules. By tak-ing advantage of supramolecular concepts, numerous supramolecular enzyme mimics with complex and hierarchical structures have been designed and investigated. Through the study of supramolecular enzyme models, a great deal of information to aid our understanding of the mechanism of catalysis by natural enzymes has been acquired. With the development of supramolec-ular artificial enzymes, it is possible to replicate the features of natural enzymes with regards to their constitutional complexity and cooperative motions, and eventually decipher the conformation-based catalytic mystery of natural enzymes. | DONG ZeYuan ZHU JunYan LUO Quan LIU JunQiu | 2013 | Science China Chemistry2013，56，8： | 2 |
| 6 | Performance and prospects of payments for ecosystem services programs: Evidence from China显示文摘 | Wu Yang Wei Liu Andrés Vi?a Junyan Luo Guangming He Zhiyun Ouyang Hemin Zhang Jianguo Liu | 2013 | Journal of Environmental Management2013，，： | 1 |
| 7 | Efficient CHzNHzPbl3 perovskite solar cells with 2TPA- n-DP hole-transporting layers显示文摘 | Lifeng Zhu Junyan Xiao Jiangjian Shi Junjie Wang Songtao Lv Yuzhuan Xu Yanhong Luo YinXiao Shirong Wang Qingbo Meng Xianggao Li Dongmei Li | 2015 | Nano Research2015，8，4： | 1 |
| 8 | Calculation of the current noise spectrum in mesoscopic transport:A quantum master equation approach显示文摘 | JunYan Luo Xin-Qi Li YiJing Yan | 2007 | Phys Rev B2007，76，08： | 1 |
| 9 | Quantum master-equation approach to quantum transport through mesoscopic systems显示文摘 | Xin-Qi Li JunYan Luo Yong-Gang Yang | 2005 | Phys Rev B2005，71，20： | 1 |
| 10 | Impact of Side Branch Lesion Length on Clinical Outcome after Coronary Stenting Techniques in Patients with Coronary Artery Bifurcation Disease:A Meta-Analysis显示文摘Objective:The optimal percutaneous coronary intervention(PCI)technique for bifurcation lesions remains controversial,especially considering the variability of the side branch(SB).A provisional stenting technique is currently recommended in most cases.This meta-analysis aimed to compare outcomes of different bifurcation PCI strategies,clarifying their scope of application.Methods:Randomized controlled trials comparing PCI strategies for coronary bifurcation lesions were systematically retrieved from PubMed,Cochrane,Web of Science,and EBSCO literature databases without limitations on published date or language.Major adverse cardiovascular events(MACEs)were stipulated as main outcomes.Secondary outcomes of interest were all-cause mortality,cardiovascular mortality,target lesion revascularization(TLR),target vessel revascularization,myocardial infarction(MI),and stent thrombosis.Both pooled analysis and sub-group analysis were performed.Results:Twenty-three randomized controlled trials with 6380 participants were included.Eighteen studies compared the provisional strategy with 2-stent approaches.No significant difference in MACEs(relative risk(RR),1.16;95%confidence interval(CI),0.90-1.48;I2=62%)was found between 1-stent and 2-stent techniques.However,when SB lesion length was used as the separation condition,the 2-stent strategy was associated with fewer MACEs(RR,1.87;95%CI,1.46-2.41;I2=70%),TLRs(RR,2.13;95%CI,1.50-3.02;I2=59%),and MIs(RR,2.17;95%CI,1.19-3.95;I2=52%)than the provisional strategy in those where SB lesions measured>10 mm long.Conclusions:In the current work,there was no significant difference between 1-stent and 2-stent techniques in terms of MACEs or secondary outcomes.However,2-stent approaches have clinical advantages over the provisional strategy in bifurcation when the SB lesion length is>10 mm due to fewer cases of TLR and MI. | Junyan Kan Shuai Luo Dongchen Wang Dandan Cai Xiaojuan Zhang Jing Kan | 2022 | Cardiology Discovery2022，2，3： | 1 |
| 11 | Preparation and comparative evaluation of well-defined fluorinated acrylic copolymer latex and solution for ancient stone protection显示文摘 | Ling He Junyan Liang Xiang Zhao Weidong Li Hongjie Luo | 2010 | Progress in Organic Coatings2010，，4： | 1 |
| 12 | Effect of thidiazuron on somatic embryogenesis of Cayratia japonica显示文摘 | Junyan Zhou Hui Ma Fuxing Guo Xintan Luo | 1994 | Plant Cell Tissue and Organ Culture1994，，1： | 1 |
| 13 | Building Sustainable Cities in China:Experience,Challenges,and Prospects显示文摘According to the 2030 Agenda for Sustainable Development,the sustainable development goal 11 is to“make cities and human settlement inclusive,safe,resilient and sustainable”.China has been making great effort in this respect.With the advancement in science and technology,the concepts of green development,environmental friendliness,and fair development are gradually moving from theories to practices,guiding the construction and development of sustainable cities in China.Over the past 40 years of reform and opening up,the overall process of China’s construction of sustainable cities and development can be divided into three stages:the initial practice stage(1986–2000),the stage focusing on transformation(2001–2012),and the stage emphasizing coordinated development and social fairness(2012 to present).During the process,China has proposed and carried out a series of pilot demonstrations of sustainable cities,eco-cities,garden cities,low-carbon cities,livable cities,resilient cities,sanitary cities,sponge cities,and circular economy cities.It has achieved remarkable results with valuable experience;meanwhile,it still faces many challenges considering the current practices.With the integration of planning for the national economy and social development,rural and urban development,land use,and other aspects,as well as the implementation of the 2030 Agenda for Sustainable Development,sustainable urban practices in China will receive more policy support and effective administrative support.As the largest developing country in the world,China’s practice in sustainable urban development undoubtedly has a broad demonstration effect and can contribute to global sustainable development. | KANG Wenmei WANG Mou LIU Junyan LV Xianhong ZHANG Ying LUO Dongshen WANG Dawei | 2019 | Chinese Journal of Urban and Environmental Studies2019，7，1： | 0 |
| 14 | 靶向eIF4AI的N-末端抑制其催化循环显示文摘文章简介蛋白翻译是中心法则的最后一环,是控制细胞内蛋白质稳态的关键生命过程。蛋白翻译起始是整个翻译过程中最关键的限速步骤,翻译过程的失调与神经发育类疾病以及恶性肿瘤等多种疾病密切相关。真核蛋白翻译起始因子eIF4A是最早被发现的DEAD盒(DEAD-box)RNA解旋酶超家族成员。 | 蒋晨晓 汤叶根 丁露露 Renke Tan Xiaojing Li Junyan Lu Jing Jiang Zhaomeng Cui Zhewei Tang Wei Li Zhangjun Cao Tilman Schneider-Poetsch Wei Jiang Cheng Luo 丁滪 刘建伟 党永军 | 2020 | 科学新闻2020，，2： | 0 |
| 15 | Vitamin A deficiency suppresses CEACAM1 to impair colonic epithelial barrier function via downregulating microbial-derived short-chain fatty acids显示文摘Vitamin A (VA) plays an essential role in modulating both the gut microbiota and gut barrier function.Short-chain fatty acids (SCFAs),as metabolites of the gut microbiota,protect the physiological intestinal barrier;however,they are compromised when VA is deficient.Thus,there is an urgent need to understand how and which SCFAs modulate colonic epithelial barrier integrity in VA deficiency (VAD).Herein,compared with normal VA rats (VAN),at the beginning of pregnancy,we confirmed that the colonic desmosome junction was impaired in the VAD group,and the amounts of acetate,propionate,and butyrate declined because of the decreased abundance of SCFA-producing bacteria (Romboutsia ,Collinsella ,and Allobaculum ).The differentially expressed genes correlated with the gut barrier and the histone deacetylase complex between the VAD and VAN groups were enriched by RNA sequencing.In the VAD group,the expression levels of colonic CEA cell adhesion molecule 1 (CEACAM1) were down-regulated,and the levels of histone deacetylase 1 (HDAC1) and HDAC3 were up-regulated.Intriguingly,the above changes in the VAD groups were rescued by VA supplementation in the early postnatal period.Further study indicated that in Caco-2 cells,butyrate treatment significantly repressed the enrichment of HDAC3 on the promoter of the CEACAM1 gene to induce its expression.Our findings support that butyrate intervention can alleviate the impairment of colonic barrier function caused by VAD,and timely postnatal VA intervention may reverse the damage caused by VAD on gut barrier integrity during pregnancy. | Junyan Yan Lu Xiao Di Feng Baolin Chen Ting Yang Bei Tong Ruifang Luo Yuting Wang Jie Chen | 2024 | Genes & Diseases2024，11，2： | 0 |
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