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| 1 | Psychophysiological Effects of Bamboo Plants on Adults显示文摘The present study was conducted to clarify the psychophysiological relaxation effects of viewing bamboo on university students. Forty healthy Chinese participants enrolled in this study to clarify the psychophysiological relaxation effects of viewing bamboo. The effects of visual stimulation using a pot both with and without a bamboo were recorded by measuring the student's blood pressure, EEG and STAI. We observed that viewing bamboo plants resulted in significantly lower systolic(female, P < 0.001; male, P < 0.001; P < 0.05) and diastolic(female,P < 0.001; male, P < 0.001; P < 0.05) blood pressures, but no changes in the pulse rate(female, P = 0.09; male, P = 0.07; P > 0.05) were observed. The results of the EEG analysis indicated brainwave variation(all P < 0.05) and lower anxiety scores(P < 0.01) after 3 min of viewing bamboo compared with the control. These findings indicate that visual stimulation with bamboo plants induced psychophysiological relaxation effects on adults. | Ahmad Hassan CHEN Qi Bing JIANG Tao LYU Bing Yang LI Nian LI Shu SHANGGUAN Zi Yue LI Yun Ting JUN Zhou Li LUO Qian CHEN Xin Yi WANG Yi Yan ZENG Cheng Cheng YANG Jun Muhammad Sohaib Tahir | 2017 | Biomedical and Environmental Sciences2017，30，11： | 8 |
| 2 | Facile Fabrication of Cellulosic Paper-based Composites with Temperature-controlled Hydrophobicity and Excellent Mechanical Strength显示文摘In this paper,we presented a novel strategy to employ a plantderived carbohydrate polymer,i.e.,cellulose,to prepare a hydrophobic composite.Cellulose was used as a scaffold,and ethylene-propylene side by side(ES)fiber was thermally melted and then coated on the cellulose surface to achieve hydrophobicity.Experimental results revealed that the thermocoating ES fibers greatly increased the water contact angle of the cellulose scaffold from 25°to 153°while simultaneously enhanced the wet tensile strength of the composite approximately 6.7-fold(drying temperature of 170℃)compared with the pure cellulose paper.In particular,compared with other related research,the prepared cellulose-based composite possessed excellent hydrophobicity and superior mechanical strength,which introduces a new chemical engineering approach to prepare hydrophobic cellulose-based functional materials. | Tongtong Yun Yilin Wang Jie Lu Yi Cheng Yanna Lyu Haisong Wang | 2020 | Paper And Biomaterials2020，5，2： | 6 |
| 3 | Vertical Distribution Characteristics of PM2.5 Observed by a Mobile Vehicle Lidar in Tianjin, China in 2016显示文摘We present mobile vehicle lidar observations in Tianjin, China during the spring, summer, and winter of 2016. Mobile observations were carried out along the city border road of Tianjin to obtain the vertical distribution characteristics of PM_(2.5). Hygroscopic growth was not considered since relative humidity was less than 60% during the observation experiments. PM_(2.5) profile was obtained with the linear regression equation between the particle extinction coefficient and PM_(2.5) mass concentration. In spring, the vertical distribution of PM_(2.5) exhibited a hierarchical structure. In addition to a layer of particles that gathered near the ground, a portion of particles floated at 0.6–2.5-km height. In summer and winter, the fine particles basically gathered below 1 km near the ground. In spring and summer, the concentration of fine particles in the south was higher than that in the north because of the influence of south wind. In winter, the distribution of fine particles was opposite to that measured during spring and summer. High concentrations of PM_(2.5) were observed in the rural areas of North Tianjin with a maximum of 350 μg m–3 on 13 December2016. It is shown that industrial and ship emissions in spring and summer and coal combustion in winter were the major sources of fine particles that polluted Tianjin. The results provide insights into the mechanisms of haze formation and the effects of meteorological conditions during haze–fog pollution episodes in the Tianjin area. | Lihui LYU Yunsheng DONG Tianshu ZHANG Cheng LIU Wenqing LIU Zhouqing XIE Yan XIANG Yi ZHANG Zhenyi CHEN Guangqiang FAN Leibo ZHANG Yang LIU Yuchen SHI Xiaowen SHU | 2018 | Journal of Meteorological Research2018，32，1： | 5 |
| 4 | Advances in Biodegradation of Aflatoxins显示文摘Aflatoxins are secondary metabolites of fungi such as Aspergillus flavus and Aspergillus parasiticus. They are one of the contaminants most common in food and feed, with high toxicity and carcinogenicity. Aflatoxins usually enter animal body together with feed and then enter human body by food chain, thereby seriously threatening human health. In recent years, the degradation of aflatoxins has become a hot research topic. This study overviewed the characteristics and detoxification ways of aflatoxins, specifically for the advances in biodegradation and degradation products of aflatoxins. | Yi WANG Chunxia ZHAO Yucai LYU Wei CHENG Peng GUO | 2016 | Agricultural Science & Technology2016，17，4： | 2 |
| 5 | Lipidomic and transcriptomic analysis reveals reallocation of carbon flux from cuticular wax into plastid membrane lipids in a glossy“Newhall”navel orange mutant显示文摘Both cuticle and membrane lipids play essential roles in quality maintenance and disease resistance in fresh fruits.Many reports have indicated the modification of alternative branch pathways in epicuticular wax mutants;however,the specific alterations concerning lipids have not been clarified thus far.Here,we conducted a comprehensive,timeresolved lipidomic,and transcriptomic analysis on the“Newhall”navel orange(WT)and its glossy mutant(MT)“Gannan No.1”.The results revealed severely suppressed wax formation accompanied by significantly elevated production of 36-carbon plastid lipids with increasing fruit maturation in MT.Transcriptomics analysis further identified a series of key functional enzymes and transcription factors putatively involved in the biosynthesis pathways of wax and membrane lipids.Moreover,the high accumulation of jasmonic acid(JA)in MT was possibly due to the need to maintain plastid lipid homeostasis,as the expression levels of two significantly upregulated lipases(CsDAD1 and CsDALL2)were positively correlated with plastid lipids and characterized to hydrolyze plastid lipids to increase the JA content.Our results will provide new insights into the molecular mechanisms underlying the natural variation of plant lipids to lay a foundation for the quality improvement of citrus fruit. | Haoliang Wan Hongbo Liu Jingyu Zhang Yi Lyu Zhuoran Li Yizhong He Xiaoliang Zhang Xiuxin Deng Yariv Brotman Alisdair RFernie Yunjiang Cheng Weiwei Wen | 2020 | Horticulture Research2020，7，1： | 2 |
| 6 | Disinfection and Protective Measures for Makeshift Hospitals显示文摘During the COVID-19 epidemic,Wuhan city had the hardest hit in China.The treatment capacity of the local medical system exceeded due to the rapid growth of COVID-19 cases.As a result,a considerable part of diagnosed patients could not be admitted to hospitals for isolation and treatment in time,causing the risk of spreading in the community.To effectively achieve the goals of controlling the source of infection by cutting off the transmission route,increasing the cure rate and reducing the mortality rate,Wuhan has reconstructed several makeshift hospitals based on large public places. | WANG Jia Qi LIU Xiao Li DUAN Hong Yang CHEN Xiao Min QIAN Le LYU Xi Fang CHENG Yi Bin LIANG Jian Sheng YAO Xiao Yuan | 2020 | Biomedical and Environmental Sciences2020，33，12： | 2 |
| 7 | Somatic mutation contributing to clonal haematopoiesis is a risk factor of recurrent stroke in first-ever acute ischaemic stroke:a prospective cohort study显示文摘Background Somatic mutation contributes to clonal haematopoiesis of indeterminate potential(CHIP)is related to age and associated with a higher risk of stroke and atherosclerotic cardiovascular disease.Here,we investigated the prognostic significance of CHIP in a large first-ever acute ischaemic stroke(AIS)cohort and explored the underlying mechanisms.Methods We studied a prospective cohort of 6016 patients who had a first-ever AIS in China.Whole-genome sequencing was performed to identify CHIP.High-sensitivity C reactive protein(hs-CRP)levels above 3 mg/L at baseline were defined as hyperinflammation.Recurrent stroke during the 3-month follow-up was the primary outcome.Results Among the 6016 patients who had a first-ever AIS,with a median age was 62 years(IQR,54.0‒70.0),3.70%were identified as CHIP carriers.The most common mutations occurred in the DNMT3A(30.0%)and TET2(11.4%)genes.During a follow-up of 3 months,the presence of CHIP was associated with recurrent stroke(HR 1.62,95%CI 1.04 to 2.51,p=0.03),recurrent ischaemic stroke(HR 1.64,95%CI 1.04 to 2.58,p=0.03)and combined vascular events(HR 1.58,95%CI 1.02 to 2.44,p=0.04)after adjusting for hsCRP levels at baseline in patients who had a first-ever AIS.Subgroup analysis demonstrated that CHIP was only associated with recurrent stroke when patients under hyperinflammation(OR 3.10,95%CI 1.92 to 5.00,p<0.001)but not in those without hyperinflammation(OR 0.18,95%CI 0.03 to 1.04,p=0.06,Pinteraction=0.002).Conclusion Our results suggest that somatic mutations contributing to CHIP increase the risk of short-term recurrent stroke in patients who had a first-ever AIS.Hyperinflammation may be important in the relationship between CHIP and recurrent stroke. | Xin Qiu Yalun Dai Si Cheng Hong-Qiu Gu Yong Jiang Xia Meng Yilong Wang Xingquan Zhao Yingyu Jiang Zhe Xu Xinying Huang Meng Wang Tian Jie Lyu Yubo Wang Jiaxu Weng Lingyun Cui Yi Shangguan Hao Li Yongjun Wang Zixiao Li | 2023 | Stroke & Vascular Neurology2023，8，2： | 1 |
| 8 | Human Serum-derived Extracellular Vesicles Protect A549 from PM_(2.5)-induced Cell Apoptosis显示文摘Objective Epidemiological studies reveal that exposure to fine particulate matter(aerodynamic diameter≤2.5μm,PM_(2.5))increases the morbidity and mortality of respiratory diseases.Emerging evidence suggests that human circulating extracellular vesicles(EVs)may offer protective effects against injury caused by particulate matter.Currently,however,whether EVs attenuate PM_(2.5)-induced A549 cell apoptosis is unknown.Methods EVs were isolated from the serum of healthy subjects,quantified via nanoparticle tracking analysis,and qualified by the marker protein CD63.PM_(2.5)-exposed(50μg/mL)A549 cells were pretreated with 10μg/mL EVs for 24 h.Cell viability,cell apoptosis,and AKT activation were assessed via Cell Counting Kit-8,flow cytometry,and Western blot,respectively.A rescue experiment was also performed using MK2206,an AKT inhibitor.Results PM_(2.5)exposure caused a 100%in crease in cell apoptosis.EVs treatme nt reduced cell apoptosis by 10%,promoted cell survival,and inhibited the PM_(2.5)-induced upregulation of Bax/Bcl2 and cleaved caspase 3/caspase 3 in PM_(2.5)-exposed A549 cells.Moreover,EVs treatment reversed PM_(2.5)-induced reductions in p-AKT^(Thr308)and p-AKT^(Ser473).A KT inhibition attenuated the anti-apoptotic effect of EVs treatment on PM_(2.5)-exposed A549 cells.Conclusions EVs treatment promotes cell survival and attenuates PM_(2.5)-induced cell apoptosis via AKT phosphorylation.Human serum-derived EVs may be an efficacious novel therapeutic strategy in PM_(2.5)-induced lung injury. | ZHOU Qiu Lian BAI Yu Zheng GAO Juan DUAN Yi LYU Yi Cheng GUAN Long Fei ELKIN Kenneth XIE Yu Ling JIAO Zheng WANG Hong Yun | 2021 | Biomedical and Environmental Sciences2021，34，1： | 0 |
| 9 | A conceived model of“physician scientist”cultivation:exploring the double degrees of MD-PhD program显示文摘To the Editor:With the rapid economic growth and improvement of people's living standards in China,ever-greater demands for high-level health-care services hre expected.These expectations are bringing new challenges to the development of clinical doctors.However,the traditional path for doctor training is inadequate to meet these challenges,as both clinical and scientific practices are important for doctors but difficult to integrate into medical education.Thus,the current medical training system is challenged to combine scientific research training with conventional clinical training.To provide possible sol-utions,Health Science Center(HSC)of Xian Jiaotong University(XJTU)has been exploring a new mode of developing physician scientists:The Double Doctoral Program(DDP)。 | Wei-Jiang Dong Wen-Bin Liu Hui-Lin Gong Yan-Bin Cheng Ming Zhang Yi Lyu Xiao-Jian Wu Xiao-Jun Meng She-Min Lyu Li-Na Chen Qian Guo Jin-Song Zhou Hong Yan | 2020 | Chinese Medical Journal2020，，13： | 0 |
| 10 | Transcription factor CsESE3 positively modulates both jasmonic acid and wax biosynthesis in citrus显示文摘PLIP lipases can initiate jasmonic acid(JA)biosynthesis.However,little is known about the transcriptional regulation of this process.In this study,an ERF transcription factor(CsESE3)was found to be co-expressed with all necessary genes for JA biosynthesis and several key genes for wax biosynthesis in transcriptomes of‘Newhall’navel orange.CsESE3 shows partial sequence similarity to the well-known wax regulator SHINEs(SHNs),but lacks a complete MM protein domain.Ectopic overexpression of CsESE3 in tomato(OE)resulted in reduction of fruit surface brightness and dwarf phenotype compared to the wild type.The OE tomato lines also showed significant increases in the content of wax and JA and the expression of key genes related to their biosynthesis.Overexpression of CsESE3 in citrus callus and fruit enhanced the JA content and the expression of JA biosynthetic genes.Furthermore,CsESE3 could bind to and activate the promoters of two phospholipases from the PLIP gene family to initiate JA biosynthesis.Overall,this study indicated that CsESE3 could mediate JA biosynthesis by activating PLIP genes and positively modulate wax biosynthesis.The findings provide important insights into the coordinated control of two defense strategies of plants represented by wax and JA biosynthesis. | Haoliang Wan Haiji Qiu Zhuoran Li Xiaoliang Zhang Jingyu Zhang Deyuan Jiang Alisdair RFernie Yi Lyu Yunjiang Cheng Weiwei Wen | 2022 | aBIOTECH2022，3，4： | 0 |
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