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| 1 | The PI3K/Akt/GSK-3β/ROS/eIF2B pathway promotes breast cancer growth and metastasis via suppression of NK cell cytotoxicity and tumor cell susceptibility显示文摘Objective: To examine the effect of pSer9-GSK-3β on breast cancer and to determine whether the underlying metabolic and immunological mechanism is associated with ROS/eIF2B and natural killer(NK) cells.Methods: We employed TWS119 to inactivate GSK-3β by phosphorylating Ser9 and explored its effect on breast cancer and NK cells. The expression of GSK-3β, natural killer group 2 member D(NKG2D) ligands, eIF2B was quantified by PCR and Western blot. We measured intracellular reactive oxygen species(ROS) and mitochondrial ROS using DCFH-DA and MitoSOX^(TM) probe,respectively, and conducted quantitative analysis of cellular respiration on 4T1 cells with mitochondrial respiratory chain complex Ⅰ/Ⅲ kits.Results: Our investigation revealed that TWS119 downregulated NKG2D ligands(H60 a and Rae1), suppressed the cytotoxicity of NK cells, and promoted the migration of 4T1 murine breast cancer cells. Nevertheless, LY290042, which attenuates p-GSK-3β formation by inhibiting the PI3K/Akt pathway, reversed these effects. We also found that higher expression of p Ser9-GSK-3β induced higher levels of ROS, and observed that abnormality of mitochondrial respiratory chain complex Ⅰ/Ⅲ function induced the dysfunction of GSK-3β-induced electron transport chain, naturally disturbing the ROS level. In addition, the expression of NOX3 and NOX4 was significantly up-regulated, which affected the generation of ROS and associated with the metastasis of breast cancer. Furthermore, we found that the expression of pSer535-eIF2B promoted the expression of NKG2D ligands(Mult-1 and Rae1) following by expression of pSer9-GSK-3β and generation of ROS.Conclusions: The PI3K/Akt/GSK-3β/ROS/eIF2B pathway could regulate NK cell activity and sensitivity of tumor cells to NK cells,which resulted in breast cancer growth and lung metastasis. Thus, GSK-3β is a promising target of anti-tumor therapy. | Fengjiao Jin Zhaozhen Wu Xiao Hu Jiahui Zhang Zihe Gao Xiao Han Junfang Qin Chen Li Yue Wang | 2019 | Cancer Biology & Medicine2019，16，1： | 20 |
| 2 | An ACC Oxidase Gene Essential for Cucumber Carpel Development显示文摘在植物的性决心产生便于 outcrossing 并且提高基因差异的单性的花。在黄瓜和甜瓜,乙烯支持心皮开发并且逮捕雄蕊开发。五性决心基因被识别了,包括四个编码在乙烯生合成催化限制率的步骤的 1-aminocyclopropane-1-carboxylate (ACC ) synthase,和抄写因素基因在甜瓜对应于孟德尔的地点 gynoecious 并且是女性的一个否定管理者的 CmWIP1。ACC oxidase (ACO ) 把 ACC 变换成乙烯;然而,它留下逃犯在黄瓜染色体的基因为性决心是它 ACO 并且怎么批评的 CmWIP1 镇压女花的开发。在这研究,我们在 ACO 基因发现了那个变化, CsACO2,在忍受仅仅男的花的黄瓜授与 androecy。变化破坏 CsACO2 的酶的活动,导致从射击尖端的 50% 更少的乙烯排放。CsACO2 在心皮 primordia 被表示,它的表示为性决心在关键阶段在女花与 CsACS11 的重叠了,大概提供为合适的 CsACS2 要求的足够的乙烯表示。CmACO3, CsACO2 的 ortholog,在心皮区域显示出一个类似的表示模式,建议 CsACO2/CmACO3 的保存功能。我们表明了那 CsWIP1, CmWIP1 的 ortholog,能直接绑 CsACO2 的倡导者并且镇压它的表示。一起拿,我们建议由 WIP1 抄写因素和 ACO 组成的一个大概保存的规章的模块在黄瓜和甜瓜控制单性的花开发。 | Huiming Chen Jinjing Sun Shuai Li Qingzhi Cui Huimin Zhang Fengjiao Xin Huaisong Wang Tao Lin Dongli Gao Shenhao Wang Xia Li Donghui Wang Zhonghua Zhang Zhihong Xu Sanwen Huang | 2016 | Molecular Plant2016，9，9： | 16 |
| 3 | Generation of B Cell-Deficient Pigs by Highly Efficient CRISPR/Cas9-Mediated Gene Targeting显示文摘Generating B cell-deficient mutant is the first step to produce human antibody repertoires in large animal models. In this study, we applied the clustered regularly interspaced short palindromic repeat(CRISPR)/CRISPR-associated(Cas) system to target the JHregion of the pig Ig M heavy chain gene which is crucial for B cell development and differentiation. Transfection of Ig M-targeting Cas9 plasmid in primary porcine fetal fibroblasts(PFFs) enabled inducing gene knock out(KO) in up to 53.3% of colonies analyzed, a quarter of which harbored biallelic modification, which was much higher than that of the traditional homologous recombination(HR). With the aid of somatic cell nuclear transfer(SCNT) technology, three piglets with the biallelic Ig M heavy chain gene mutation were produced. The piglets showed no antibody-producing B cells which indicated that the biallelic mutation of the Ig M heavy chain gene effectively knocked out the function of the Ig M and resulted in a B cell-deficient phenotype. Our study suggests that the CRISPR/Cas9 system combined with SCNT technology is an efficient genome-editing approach in pigs. | Fengjiao Chen Ying Wang Yilin Yuan Wei Zhang Zijian Ren Yong Jin Xiaorui Liu Qiang Xiong Qin Chen Manling Zhang Xiaokang Li Lihua Zhao Ze Li Zhaoqiang Wu Yanfei Zhang Feifei Hu Juan Huang Rongfeng Li Yifan Dai | 2015 | Journal of Genetics and Genomics2015，42，8： | 15 |
| 4 | Stabilizing nickel sulfide nanoparticles with an ultrathin carbon layer for improved cycling performance in sodium ion batteries显示文摘Nanostructured 金属硫化物是为钠离子电池的潜在的电极材料;然而,他们典型地由于大体积变化和分泌物产品的溶解受不了很差的骑车的稳定性。此处,我们建议合理材料设计策略让基于硫化物的材料处理这些问题。拿镍硫化物(是的 NiS x ) 一个例子,我们证明它的电气化学的性能能被限制 NiS 在滤的 x nanoparticles 传导性的碳 nanotube 网络,并且与 ultrathin 碳涂层层稳定他们。碳层用作一个物理障碍减轻体积变化和活跃材料的溶解的效果。混合材料展出了一个大可逆特定的能力 > 超过 200 的 500 mAh/g 和优秀骑车稳定性骑车。作为电池阳极材料给 NiS x 的传统地有问题的性质,我们相信这里报导的观察高效反映我们的材料设计策略的有效性。 | Feipeng Zhao Qiufang Gong Brian Traynor Duo Zhang Jiaojiao Li Hualin Ye Fengjiao Chen Na Han Yeyun Wang Xuhui Sun Yanguang Li | 2016 | Nano Research2016，9，10： | 6 |
| 5 | A Study on Spatial Interpolation of Temperature in Anhui Province Based on ANUSPLIN显示文摘To achieve refined temperature grid data with high accuracy and high spatial resolution,hourly temperature grid dataset with spatial resolution of 1 km in Anhui Province from January to December in 2016 was established using the ANUSPLIN thin plate spline algorithm,which meets the needs of climate change research and meteorological disaster risk assessment. And the interpolation error was analyzed. The results show that the interpolated values of hourly temperature by ANUSPLIN are close to the observed values in 2016. The error is generally below 1. 5 ℃,and the root mean square error is 0. 937 6 ℃. On monthly scale,the interpolated values of hourly temperature by ANUSPLIN are also close to the observed values.In October,November,June and May,the interpolation accuracy is the highest,and the proportion of absolute error of hourly temperature lower than 2 ℃ is up to 99%,97. 4%,98. 1% and 97. 4% respectively. In February,March,August and December,the interpolation accuracy is the lowest,and the proportion of absolute error higher than 2 ℃ is 8. 1%,5. 3%,4. 1% and 4. 2% respectively. Due to the effect of complex topography in Anhui,the interpolation accuracy is the lowest in the mountainous areas of southern and western Anhui,and the interpolation error in these regions even exceeds 1. 5 ℃ annually and 1. 8 ℃ monthly. | Wen Huayang Chen Fengjiao Li Jun Qiu Kangjun Wang Gen | 2019 | Meteorological and Environmental Research2019，10，2： | 5 |
| 6 | Augmented renal clearance in Chinese intensive care unit patients after traumatic brain injury: a cross-sectional study显示文摘To the Editor:Augmented renal clearance(ARC)refers to an enhanced elimination of circulating solutes,including drugs,by the kidneys at a rate statistically higher than normal.On the first day of intensive care unit(ICU)admission,ARC occurrence may predict continued creatinine clearance(CrCl)elevation for 1 day to several weeks.[1]ARC has a substantial adverse effect on renally cleared antibiotics'pharmacokinetics/pharmacodynamics.Treatment failure or worse outcomes are more frequent in ARC patients.Thus,a'one size fits all'approach to drug dosing in ARC patients is inappropriate;dosing requires adjustment for some variables. | Zilong Dang Hong Guo Bin Li Maohua Zhen Jian Liu Yuhui Wei Hongyan Qin Zhimin Dou Lei Zhang Lei Zhu Yongqiang Cao Fengjiao Li Xinan Wu | 2022 | Chinese Medical Journal2022，，6： | 3 |
| 7 | Photocatalytic decompositions of gaseous HCHO and methylene blue with highly ordered TiO_2 nanotube arrays显示文摘The highly ordered Ti O_2nanotubes(NTs) were fabricated by the anodic oxidation method.Their morphology,structure and crystalline phase were characterized by scanning electron microscopy(SEM) and X-ray diffractometer(XRD).The effects of morphology,specific surface area,pore structures and photocatalytic activity of the Ti O_2 NTs were investigated.UV–vis spectra analysis showed that its light absorption had been extended to the visible light range.The photocatalytic activity of the as-prepared samples was evaluated by photocatalytic oxidation of gaseous HCHO and MB aqueous solution.The samples had better adhesion strength in the dark and showed a higher photocatalytic activity than nanoparticles.Especially,with ultraviolet light pretreatment,the nanotubes exhibited more stable active for photocatalytic decomposition and the photodecomposition rate remained at high level after 3 cycles of the photocatalysis experiment.Thus,how the number of surface active group ·OH increased and the mechanism for the great improvement for the photocatalytic activity are discussed. | Lixia Li Jing Ya Fengjiao Hu Zhifeng Liu Lei E | 2016 | Journal of Energy Chemistry2016，25，4： | 2 |
| 8 | Controllable Biosynthesis and Properties of Gold Nanoplates Using Yeast Extract显示文摘Biosynthesis of gold nanostructures has drawn increasing concerns because of its green and sustainable synthetic process. However, biosynthesis of gold nanoplates is still a challenge because of the expensive source and difficulties of controllable formation of morphology and size. Herein, one-pot biosynthesis of gold nanoplates is proposed, in which cheap yeast was extracted as a green precursor. The morphologies and sizes of the gold nanostructures can be controlled via varying the pH value of the biomedium. In acid condition, gold nanoplates with side length from 1300 ± 200 to 300 ± 100 nm and height from 18 to 15 nm were obtained by increasing the pH value. Whereas, in neutral or basic condition, only gold nanoflowers and nanoparticles were obtained. It was determined that organic molecules, such as succinic acid, lactic acid, malic acid, and glutathione, which are generated in metabolism process, played important role in the reduction of gold ions. Besides, it was found that the gold nanoplates exhibited plasmonic property with prominent dipole infrared resonance in near-infrared region, indicating their potential in surface plasmon-enhanced applications, such as bioimaging and photothermal therapy. | Zhi Yang Zhaohui Li Xuxing Lu Fengjiao He Xingzhong Zhu Yujie Ma Rong He Feng Gao Weihai Ni Yasha Yi | 2017 | Nano-Micro Letters2017，9，1： | 2 |
| 9 | A New Indicator for Global Food Security Assessment: Harvested Area Rather Than Cropland Area显示文摘Cropland area has long been used as a key indicator of food security.However,grain yield is not solely controlled by the area of the cropland.Therefore,we proposed a new indicator to assess food security.Results show that from 1992 to 2004,the global cropland area increased by 840200 km^(2)(99.4%),but the grain yield increased only by 310 million t(29.1%);and from 2004 to 2015,the cropland area decreased by 39000 km^(2)(4.64%),but the grain yield increased by 370 million t(70.84%).This result showed that grain yield was not linearly correlated with cropland area,and delimiting the threshold of cropland protection may not guarantee food security.Combined with further correlation analysis,we found that the increase in the global grain yield was more closely related to the harvested area(R^(2)=0.94),which indicated that the harvested area is a more scientific and accurate indicator than cropland area in terms of guaranteeing food security.Therefore,if governments want to ensure the food security,they should choose a new and more accurate indicator:harvested area rather than cropland area. | SONG Fengjiao WANG Shijie BAI Xiaoyong WU Luhua WANG Jinfeng LI Chaojun CHEN Huan LUO Xuling XI Huipeng ZHANG Sirui LUO Guofeng YAN Mengqi ZHEN Qingqing | 2022 | Chinese Geographical Science2022，32，2： | 2 |
| 10 | Synthesis of selective PAK4 inhibitors for lung metastasis of lung cancer and melanoma cells显示文摘The p21 activated kinase 4(PAK4) is serine/threonine protein kinase that is critical for cancer progression.Guided by X-ray crystallography and structure-based optimization,we report a novel subseries of C-3-substituted 6-ethynyl-1 H-indole derivatives that display high potential and specificity towards group Ⅱ PAKs.Among these inhibitors,compound 55 exhibited excellent inhibitory activity and kinase selectivity,displayed superior anti-migratory and anti-invasive properties against the lung cancer cell line A549 and the melanoma cell line B16.Compound 55 exhibited potent in vivo antitumor metastatic efficacy,with over 80% and 90% inhibition of lung metastasis in A549 or B16-BL6 lung metastasis models,respectively.Further mechanistic studies demonstrated that compound 55 mitigated TGF-β1-induced epithelial-mesenchymal transition(EMT). | Peilu Song Fan Zhao Dahong Li Jiqiang Qu Miao Yao Yuan Su Hanxun Wang Miaomiao Zhou Yujie Wang Yinli Gao Feng Li Dongmei Zhao Fengjiao Zhang Yu Rao Mingyu Xia Haitao Li Jian Wang Maosheng Cheng | 2022 | Acta Pharmaceutica Sinica B2022，12，6： | 2 |
| 11 | Nano-polycrystalline diamond formation under ultra-high pressure显示文摘 | Chao Xu Duanwei He Haikuo Wang Junwei Guan Chunmei Liu Fang Peng Wendan Wang Zili Kou Kai He Xiaozhi Yan Yan Bi Lei Liu Fengjiao Li Bo Hui | 2013 | International Journal of Refractory Metals and Hard Materials2013，，： | 2 |
| 12 | Effect of Mn doping on the microstructure and magnetic properties of CuFeO2 ceramics显示文摘The effects of Mn doping on the microstructure and magnetic properties of CuFeO2 systems were studied using X-ray diffraction(XRD),X-ray photoelectron spectroscopy,scanning electron microscopy(SEM),and a physical property measurement method.The microstructure measurements demonstrated that the substitution of Mn for Fe can cause lattice distortion,promote grain growth,and change the valence state of Fe and Mn ions.Ceramic samples with doping content x=0.00−0.03 exhibited two successive magnetic transition temperature(TN)at TN1≈14 K and TN2≈10 K.TN decreased gradually with the Mn4+content,and TN2 was not observed in the x>0.05 samples within a temperature range of T=5−300 K.Magnetic hysteresis loops revealed that only anti-ferromagnetic behavior occurred in the low-doped samples(x=0.00−0.03),and the coexistence of ferromagnetism and anti-ferromagnetism was observed in the high-doped samples(x=0.05−0.10).Besides,the x=0.10 sample had a maximum magnetization of 5.98 emu/g.This study provides basic experimental data for investigating the relationship between the microstructure and magnetic properties of CuFeO2 systems. | Fengjiao Ye Haiyang Dai Ke Peng Tao Li Jing Chen Zhenping Chen Nannan Li | 2020 | Journal of Advanced Ceramics2020，9，4： | 2 |
| 13 | Knowledge management research status in China from 2006 to 2010:Based on analysis of the degree theses显示文摘 | Li Changling Guo Fengjiao Zhi Ling | 2013 | Scientometrics2013，94，1： | 1 |
| 14 | A Study on Precipitation Products with High Resolution in Anhui Province Based on Thin Plate Smoothing Spline显示文摘In order to achieve refined precipitation grid data with high accuracy and high spatial resolution,hourly precipitation grid dataset with 1 km spatial resolution in Anhui Province from May to September (in the rainy season) in 2016 and from August 2017 to July 2018 was established based on thin plate smoothing spline (TPS),which meets the needs of climate change research and meteorological disaster risk assessment.The interpolation errors were then analyzed.The grid precipitation product obtained based on thin plate smoothing spline,CLDAS-FAST and CLDAS-FRT were evaluated.The results show that the interpolated values of hourly precipitation by thin plate smoothing spline are close to the observed values in the rainy season of 2016.The errors are generally below 0.9 mm/h.However,the errors of precipitation in the mountainous areas of eastern Huaibei and western Anhui are above 1.2 mm/h.On monthly scale,the errors in June and July are the largest,and the proportion of absolute values of the errors ≥2 mm/h is up to 2.0% in June and 2.2% in July.The errors in September are the smallest,and the proportion of absolute values of the errors ≥2 mm/h is only 0.6%.The root mean square (RMSE) is only 0.37 mm/h,and the correlation coefficient (COR) is 0.93.The interpolation accuracy of CLDAS-FRT is the highest,with the smallest RMSE (0.65 mm/h) and mean error ( ME =0.01 mm/h),and the largest COR (0.81).The accuracy of the precipitation product obtained by thin plate smoothing spline interpolation is close to that of CLDAS-FAST.Its RMSE is up to 0.80 mm/h,and its ME is only -0.01 mm/h.Its COR is 0.73,but its bias (BIAS) is up to 1.06 mm/h. | Li Jun Wen Huayang Chen Fengjiao | 2019 | Meteorological and Environmental Research2019，10，3： | 1 |
| 15 | Relationship between Extreme Precipitation and Temperature in Two Different Regions:The Tibetan Plateau and Middle–East China显示文摘The change of extreme precipitation with temperature has regional characteristics in the context of global warming.In this study, radiosonde data, co-located rain gauge(RG) observations, and Tropical Rainfall Measuring Mission(TRMM) precipitation radar(PR) products are used to explore the relationship between extreme precipitation intensity and near-surface temperature in Middle–East China(MEC) and the eastern Tibetan Plateau(TP) during1998–2012. The results show that extreme precipitation intensity increases with increasing temperature at an approximate Clausius–Clapeyron(C–C) rate(i.e., water vapor increases by 7% as temperature increases by 1°C based on the C–C equation) in MEC and TP, but the rate of increase is larger in TP than in MEC. This is probably because TP(MEC) is featured with deep convective(stratiform) precipitation, which releases more(less) latent heat and strengthens the convection intensity on a shorter(longer) timescale. It is also found that when temperature is higher than 25°C(15°C) in MEC(TP), the extreme precipitation intensity decreases with rise of temperature, suggesting that the precipitation intensity does not always increase with warming. In this case, the limited atmospheric humidity and precipitable water could be the primary factors for the decrease in extreme precipitation intensity at higher temperatures. | Rui WANG Tao XIAN Mengxiao WANG Fengjiao CHEN Yuanjian YANG Xiangdong ZHANG Rui LI Lei ZHONG Chun ZHAO Yunfei FU | 2019 | Journal of Meteorological Research2019，33，5： | 1 |
| 16 | A MODEL FOR THE RELEASE BEHAVIOR OF DRUGS FROM HYDROGEL NANOPARTICLE显示文摘A model to correlate and predict the release behavior of drugs from hydrogel nanoparticles is presented in this paper. The nanoparticle is considered as a combination of a shell of an elastic semipermeable membrane and a core of a fluid phase (After swelling equilibrium). The fluid core consists of network building materials and other components that are able to partition in hydrogel nanoparticle phase and surrounding coexisting liquid phase, and is enveloped by the membrane shell. The excess Gibbs energies of the hydrogel nanoparticle phase and the surrounding coexisting fluid phase are expressed e.g. using UNIQUAC equation with “free-volume” contribution for non-ionic solution and VERS-model for ionic one. The elastic properties of polymer network could be described, for example, by the “phantom network” theory. | XU Xiaoping LI Zhongqin CHEN Xiaogeng LV Fengjiao | 2006 | Chinese Journal of Reactive Polymers2006，15，2： | 1 |
| 17 | Astrocyte elevated gene‐1 interacts with β‐catenin and increases migration and invasion of colorectal carcinoma显示文摘 | Fenfen Zhang Qingxu Yang Fengjiao Meng Huijuan Shi Hui Li Yingjie Liang Anjia Han | 2013 | Carcinog2013，，8： | 1 |
| 18 | Electrochemical removal of ammonium nitrogen in high efficiency and N_(2) selectivity using non-noble single-atomic iron catalyst显示文摘Ammonia nitrogen (NH_(4)^(+)-N) is a ubiquitous environmental pollutant,especially in offshore aquaculture systems.Electrochemical oxidation is very promising to remove NH_(4)^(+)-N,but suffers from the use of precious metals anodes.In this work,a robust and cheap electrocatalyst,iron single-atoms distributed in nitrogen-doped carbon (Fe-SAs/N-C),was developed for electrochemical removal of NH_(4)^(+)-N from in wastewater containing chloride.The FeSAs/N-C catalyst exhibited superior activity than that of iron nanoparticles loaded carbon(Fe-NPs/N-C),unmodified carbon and conventional Ti/IrO_(2)-TiO_(2)-RuO_(2)electrodes.And high removal efficiency (>99%) could be achieved as well as high N_(2)selectivity (99.5%) at low current density.Further experiments and density functional theory (DFT) calculations demonstrated the indispensable role of single-atom iron in the promoted generation of chloride derived species for efficient removal of NH_(4)^(+)-N.This study provides promising inexpensive catalysts for NH_(4)^(+)-N removal in aquaculture wastewater. | Fengjiao Quan Guangming Zhan Bing Zhou Cancan Ling Xiaobing Wang Wenjuan Shen Jianfen Li Falong Jia Lizhi Zhang | 2023 | Journal of Environmental Sciences2023，，3： | 1 |
| 19 | Gut dysbiosis of bacteria and fungi associated with human immunodeficiency virus infection显示文摘To the Editor:There have been growing concerns about the gut bacterial dysbiosis associated with HIV infection,addressing a critical role of gut bacteria in persistent chronic inflammation and severe intestinal dysfunction among the human immunodeficiency virus(HIV)infected population.However,little is known about the gut fungal dysbiosis caused by HIV-infection.Therefore,we launched a case-control study aiming to explore the gut dysbiosis of bacteria and fungi in HIV infection,which may reveal a more comprehensive feature of HIV infection-related gut dysbiosis of bacteria and fungi that possibly play a role in the chronic systemic immune activation observed in HIV infection. | Xueqi Wu Yuanhong Xu Qingfeng Li Fengjiao Yang Shenghua He Yingjie Li Shujuan Yang Peibin Zeng | 2022 | Chinese Medical Journal2022，，11： | 1 |
| 20 | A carbon-neutrality-capactiy index for evaluating carbon sink contributions显示文摘The accurate determination of the carbon-neutrality capacity(CNC)of a region is crucial for developing policies related to emissions and climate change.However,a systematic diagnostic method for determining the CNC that considers the rock chemical weathering carbon sink(RCS)is lacking.Moreover,it is challenging but indispensable to establish a fast and practical index model to determine the CNC.Here,we selected Guizhou as the study area,used the methods for different types of carbon sinks,and constructed a CNC index(CNCI)model.We found that:(1)the carbonate rock chemical weathering carbon sink flux was 30.3 t CO_(2)km^(-2)yr^(-1).Guizhou accounted for 1.8%of the land area and contributed 5.4%of the carbonate chemical weathering carbon sink;(2)the silicate rock chemical weathering carbon sink and its flux were 1.44×10^(3)t CO_(2)and 2.43 t CO_(2)km^(-2)yr^(-1),respectively;(3)the vegetation-soil ecosystem carbon sink and its flux were 1.37×10^(8)t CO_(2)and 831.70 t CO_(2)km^(-2)yr^(-1),respectively;(4)the carbon emissions(CEs)were 280 Tg CO_(2),about 2.8%of the total for China;and(5)the total carbon sinks in Guizhou were 160 Tg CO_(2),with a CNCI of 57%,which is 4.8 times of China and 2.1 times of the world.In summary,we conducted a systematic diagnosis of the CNC considering the RCS and established a CNCI model.The results of this study have a strong implication and significance for national and global CNC determination and gap analysis. | Xiaoyong Bai Sirui Zhang Chaojun Li Lian Xiong Fengjiao Song Chaochao Du Minghui Li Qing Luo Yingying Xue Shijie Wang | 2023 | Environmental Science and Ecotechnology2023，，3： | 1 |
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