|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Preliminary 3D printing of large inclined-shaped alumina ceramic parts by direct ink writing显示文摘Three dimensional(3D)printing technology by direct ink writing(DIW)is an innovative complex shaping technology,possessing advantages of flexibility in fabrication,high efficiency,low cost,and environmental-friendliness.Herein,3D printing of complex alumina ceramic parts via DIW using thermally induced solidification with carrageenan swelling was investigated.The rheological properties of the slurry under different thermally-induced modes were systematically studied.The solidification properties of thermally-induced pastes with varying contents of carrageenan were optimized.The experimental results showed that the optimized paste consisting of 0.4 wt%carrageenan could be rapidly solidified at about 55℃,which could print inclined-plane more than 60°in vertical without support,resulting in better homogeneity of the green body.A nearly pore-free structure was obtained after sintering at 1600℃ for 2 h. | Liangliang YANG Xiaojun ZENG Allah DITTA Bo FENG Lizhong SU Yue ZHANG | 2020 | Journal of Advanced Ceramics2020，9，3： | 9 |
| 2 | Informative gene selection using the Algebraic Connectivity Strength of Point and Scoring Criteria显示文摘This paper presents a novel method that integrates the Algebraic Connectivity Strength of Point(ACSP) and Scoring Criteria to identify genes associated with tumor type.First,for each gene,the ACSP is used to identify reliable expression levels of the gene in all the samples.The informative genes are then selected using Scoring Criteria based on these reliable expression levels.Finally,the Support Vector Machine(SVM) classifier is used to classify the two datasets of gene expression profiling.The results show that the informative genes selected by the proposed method have higher credibility than those selected by Scoring Criteria alone. | WANG Nian SU LiangLiang TANG Jun YE AiXia | 2013 | Chinese Science Bulletin2013，58，6： | 2 |
| 3 | New strong bounds on sub-GeV dark matter from boosted and Migdal effects显示文摘Due to the low nuclear recoils,sub-Ge V dark matter(DM)is usually beyond the sensitivity of the conventional DM direct detection experiments.The boosted and Migdal scattering mechanisms have been proposed as two new complementary avenues to search for light DM.In this study,we consider the momentum-transfer effect in the DM-nucleus scattering to derive the new bounds on sub-GeV DM for these two scenarios.We show that such an effect is sizable so that the existing bounds on the DM-nucleus scattering cross section can be improved significantly. | Victor V.Flambaum Liangliang Su Lei Wu Bin Zhu | 2023 | Science China(Physics,Mechanics & Astronomy)2023，66，7： | 1 |
| 4 | LncRNA DACH1 protects against pulmonary fibrosis by binding to SRSF1 to suppress CTNNB1 accumulation显示文摘Idiopathic pulmonary fibrosis(IPF)is a progressive disease with unknown etiology and limited therapeutic options.Activation of fibroblasts is a prominent feature of pulmonary fibrosis.Here we report that lncRNA DACH1(dachshund homolog 1)is downregulated in the lungs of IPF patients and in an experimental mouse model of lung fibrosis.LncDACH1 knockout mice develop spontaneous pulmonary fibrosis,whereas overexpression of LncDACH1 attenuated TGF-β1-induced aberrant activation,collagen deposition and differentiation of mouse lung fibroblasts.Similarly,forced expression of LncDACH1 not only prevented bleomycin(BLM)-induced lung fibrosis,but also reversed established lung fibrosis in a BLM model.Mechanistically,LncDACH1 binding to the serine/arginine-rich splicing factor 1(SRSF1)protein decreases its activity and inhibits the accumulation of Ctnnb1.Enhanced expression of SRSF1 blocked the anti-fibrotic effect of LncDACH1 in lung fibroblasts.Furthermore,loss of LncDACH1 promoted proliferation,differentiation,and extracellular matrix(ECM)deposition in mouse lung fibroblasts,whereas such effects were abolished by silencing of Ctnnb1.In addition,a conserved fragment of LncDACH1 alleviated hyperproliferation,ECM deposition and differentiation of MRC-5 cells driven by TGF-β1.Collectively,LncDACH1 inhibits lung fibrosis by interacting with SRSF1 to suppress CTNNB1 accumulation,suggesting that LncDACH1 might be a potential therapeutic target for pulmonary fibrosis. | Jian Sun Tongzhu Jin Zhihui Niu Jiayu Guo Yingying Guo Ruoxuan Yang Qianqian Wang Huiying Gao Yuhan Zhang Tianyu Li Wenxin He Zhixin Li Wenchao Ma Wei Su Liangliang Li Xingxing Fan Hongli Shan Haihai Liang | 2022 | Acta Pharmaceutica Sinica B2022，12，9： | 1 |
| 5 | A smart nanoprobe based on luminescent terbium metal-organic framework coated gold nanorods for monitoring and photo-stimulated combined thermal-chemotherapy显示文摘Real-time monitoring and accurate treatment are of great significance for reducing the side effects during the cancer therapy.In this work,we rationally prepared a smart nanoprobe based on core-shell terbium metal-organic gramework(MOF)with highly effective photothermal conversion capacity and drug release efficiency under near-infrared light irradiation for real-time fluorescence imaging-guided multimodal therapy.The nanoprobe can achieve prominent photothermal therapy and controllable drug release,act as a fluorescence thermometer,and also real-time feedback of temperature is expected to be achieved.At the same time,the two-photon ligand design significantly improves the tissue penetration ability of the nanoprobe.Our work is expected to provide a reference for precise treatment and real-time monitoring of tumors and at the same time provide new ideas for the formulation of individualized treatment plans. | Tong Zhang Liying Qin Liangliang Liu Meina Zhang Tianyi Du Yifan Fan Huicheng Yan Pingru Su Ping Zhou Yu Tang | 2022 | Journal of Rare Earths2022，40，9： | 0 |
| 6 | Microfluidic-directed magnetic controlling supraballs with multi-responsive anisotropic photonic crystal structures显示文摘The design and fabrication of anisotropic photonic crystal supraballs with multiple responses are highly desirable for versatile environmental sensing and flexible displaying.Herein,we developed an available strategy to construct a series of multi-responsive magnetic colloidal photonic crystal(CPC)supraballs with Janus and molecular-analogue structures.Initially,the humidity and temperature sensitive CPC supraballs were obtained via immobilization of polyacrylamide(PAM)and polyisopropylacrylamide(PNIPAM)hydrogels into the CPC structure,respectively,and CdTe/ZnS quantum dots endow the supraballs fluorescent signal under UV light.Furthermore,Fe_(3)O_(4) nanoparticles(NPs)were served as a magnetic hemisphere to construct CPC Janus supraballs which can be subsequently assembled into three different molecular-shaped cluster particles that integrate more response types via Fe_(3)O_(4) NPs hemisphere coalescence to a magnetic coupling center,recognizing multiple responses simultaneously that correspond the environmental altering.In addition,2D polychromatic patterns with sensitive CPC pixels printed by automatic printing system were demonstrated,which could monitor the changes of temperature and humidity.The multi-responsive magnetic controlling supraballs and 2D patterns reveal the promising applications in environmental sensing,anti-counterfeiting and displaying. | Lu-Wei Hao Ji-Dong Liu Qing Li Ren-Kun Qing Yun-Ya He Jiazhuang Guo Ge Li Liangliang Zhu Chen Xu Su Chen | 2021 | Journal of Materials Science & Technology2021，，22： | 0 |
| 7 | Oxygen vacancy-rich amorphous FeNi hydroxide nanoclusters as an efficient electrocatalyst for water oxidation显示文摘In this work,a one-pot strategy is presented to directly synthesize amorphous Fe_(x)Ni_(y) hydroxide nanoclusters(denoted as ANC-Fe_(x)Ni_(y),<2 nm)with oxygen vacancies induced by ionic liquids.The ANC-Fe_(x)Ni_(y) catalyst presents abundant catalytic sites and high intrinsic conductivity.As such,the optimized ANC-Fe_(1)Ni_(2) exhibits high activity in oxygen evolution reaction(OER)with a Tafel slope of 39 m V dec^(–1) and an overpotential of 266 m V at 10 m A cm^(-2).Notably,the optimized ANC-Fe_(1)Ni_(2) shows an extraordinarily large mass activity of 3028 Ag_(FeNi)^(–1) at the overpotential of 300 m V,which is~24-fold of commercial RuO_(2) catalyst.The superior activity of these Fe_(x)Ni_(y) hydroxide nanoclusters is ascribed to(i)the amorphous and distorted structure with abundant oxygen vacancies,and(ii)enhanced active site density by downsizing the ANC-FexNiyclusters.This strategy provides a novel route for enhancing OER electrocatalytic performance and highly encouraging for the future application of amorphous metal hydroxides in catalysis. | Youhai Cao Yang Su Liangliang Xu Xiaohua Yang Zhongkang Han Rui Cao Gao Li | 2022 | Journal of Energy Chemistry2022，31，8： | 0 |
| 8 | An improved bound on accelerated light dark matter显示文摘Light(sub-GeV)dark matter has gained increasing interest in terms of direct detection.Accelerated dark matter is a promising candidate that can generate detectable nuclear recoil energy within the sub-GeV range.Because of the large kinetic energy,its interactions with the nucleus are predominantly governed by inelastic scattering,including quasi-elastic and deep inelastic scattering.In this work,we calculated the inelastic effects in dark matter-Earth scattering mediated by a vector particle.Our analysis revealed that the impact of inelastic scattering relies on the mediator mass and the kinetic energy spectrum of dark matter.The results exhibited considerable disparity:the upper bounds of the exclusion limit for the spin-independent cross-section between accelerated dark matter and nuclei via a heavy mediator differ by several tens of times when inelastic scattering is considered. | Liangliang Su Lei Wu Bin Zhu | 2024 | Science China(Physics,Mechanics & Astronomy)2024，67，2： | 0 |
| 9 | A Novel Detection Method for Pavement Crack with Encoder-Decoder Architecture显示文摘As a current popular method,intelligent detection of cracks is of great significance to road safety,so deep learning has gradually attracted attention in the field of crack image detection.The nonlinear structure,low contrast and discontinuity of cracks bring great challenges to existing crack detection methods based on deep learning.Therefore,an end-to-end deep convolutional neural network(AttentionCrack)is proposed for automatic crack detection to overcome the inaccuracy of boundary location between crack and non-crack pixels.The AttentionCrack network is built on U-Net based encoder-decoder architecture,and an attention mechanism is incorporated into the multi-scale convolutional feature to enhance the recognition of crack region.Additionally,a dilated convolution module is introduced in the encoder-decoder architecture to reduce the loss of crack detail due to the pooling operation in the encoder network.Furthermore,since up-sampling will lead to the loss of crack boundary information in the decoder network,a depthwise separable residual module is proposed to capture the boundary information of pavement crack.The AttentionCrack net on public pavement crack image datasets named CrackSegNet and Crack500 is trained and tested,the results demonstrate that the AttentionCrack achieves F1 score over 0.70 on the CrackSegNet and 0.71 on the Crack500 in average and outperforms the current state-of-the-art methods. | Yalong Yang Wenjing Xu Yinfeng Zhu Liangliang Su Gongquan Zhang | 2023 | Computer Modeling in Engineering & Sciences2023，，10： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员