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| 1 | Gold immunochromatographic sensor for the rapid detection of twenty-six sulfonamides in foods显示文摘一个金 immunochromatographic 传感器(GICS ) 在蜂蜜样品为 26 硫安类药剂的快速的察觉被开发。传感器基于能认出所有 26 硫安类药剂的组特定的 monoclonal 抗体(mAb ) 。三 haptens (1 与 thiazole 包围的 hapten, 2 与苯包围的 hapten,和 3 与直碳锁住的 hapten ) 被用于抗原准备。与 hybridoma 技术,组特定的 mAb 与 50% 最大的禁止的集中被屏蔽(对 sulfathizole (STZ ) 和从 0.08 ~ 90.18 ng/mL 的另外的 25 类似物的 IC 50) 。单音分散金 nanoparticles 与 mAb 被结合开发侧面的 immunochromatographic 长带。0.1 g/mL 的标记的抗体集中和在测试线的 0.2 g/mL 的涂层抗原集中为长带准备被选择。在优化条件,为 STZ 的集中的察觉( vLOD )的视觉限制, sulfamethoxazole , sulfamethizole ,磺胺嘧啶, sulfamerazine , sulfadimethoxine , sulfamonomethoxine , sulfameter , sulfamethoxypyridazine ,和 sulfachloropyridazine 下面是 5 , 0.25 , 0.25 , 10 , 5 , 10 , 25 , 2.5 , 5 , 0.25 ,和 10 g/kg 分别地。在蜂蜜样品的扫描仪分析为 26 硫安类药剂的察觉揭示了好性能。商业蜂蜜样品与传感器被测试,积极结果与高效的液体层析被证实。建议脱衣传感器在爱人样品为硫安类药剂污染物质的快速、可靠的决心提供一个方便方法。 | Yanni Chen Liqiang Liu Liguang Xu Shanshan Song Hua Kuang Gang Cui Chuanlai Xu | 2017 | Nano Research2017，10，8： | 11 |
| 2 | ADVANCES IN UNDERSTANDING AND FORECASTING RAPIDLY CHANGING PHENOMENA IN TROPICAL CYCLONES显示文摘This review of new understanding and forecasting of tropical cyclones(TCs) is based on presentations at the International Top-level Forum on Rapid Change Phenomena in Tropical Cyclones in Haikou, China. The major topics are the sudden changes in tracks, rapid changes in structure and intensity, rapid changes in rainfall, and advances in forecasting and forecaster requirements. Although improved track forecast guidance has been achieved with the Australian ACCESS-TC model and in track forecasts to 120 h by the China Meteorological Administration, there is a continuing need for better understanding and improved track forecast guidance. Advances in understanding of processes related to rapid intensification(RI), secondary eyewall formation, mechanisms controlling inner-core structure and size changes, and structure and intensity changes at landfall have been achieved, but progress in prediction of rapid changes in structure and intensity has been slow. Taking into account complex interactions involved in TC-related rainfall, a prioritized list of physical processes that govern rainfall from landfalling TCs in China has been developed. While forecaster participants were generally encouraged by the progress being made, they expressed a strong desire for a transition of that new knowledge to timely and reliable forecast guidance products. | RUSSELL L.ELSBERRy LIANSHOU CHEN JIM DAVIDSON ROBERT ROGERS YUQING WANG LIGUANG WU | 2013 | Tropical Cyclone Research and Review2013，2，1： | 7 |
| 3 | Allele-aware chromosome-scale assembly of the allopolyploid genome of hexaploid Ma bamboo(Dendrocalamus latiflorus Munro)显示文摘Dendrocalamus latiflorus Munro is a woody clumping bamboo with rapid shoot growth.Both genetic transformation and clustered regularly interspaced short palindromic repeats(CRISPR)/CRISPR-associated protein 9(Cas9)gene editing techniques are available for D.latiflorus,enabling reverse genetic approaches.Thus,D.latiflorus has the potential to be a model bamboo species.However,the genome sequence of D.latiflorus has remained unreported due to its polyploidy and large genome size.Here,we sequenced the D.latiflorus genome and assembled it into three allele-aware subgenomes(AABBCC),representingthe largest genome of a major bamboo species.We assembled 70 allelic chromosomes(2,737 Mb)for hexaploid D.latiflorus using both singlemolecule sequencing from the Pacific Biosciences(Pac Bio)Sequel platform and chromosome conformation capture sequencing(Hi-C).Repetitive sequences comprised 52.65%of the D.latiflorus genome.We annotated 135231 protein-coding genes in the genome based on transcriptomes from eight different tissues.Transcriptome sequencing using RNA-Seq and Pac Bio singlemolecule real-time long-read isoform sequencing revealed highly differential alternative splicing(AS)between non-abortive and abortive shoots,suggesting that AS regulates the abortion rate of bamboo shoots.This high-quality hexaploid genome and comprehensive strand-specific transcriptome datasets for this Poaceae family member will pave the way for bamboo research using D.latiflorus as a model species. | Yushan Zheng Deming Yang Jundong Rong Liguang Chen Qiang Zhu Tianyou He Lingyan Chen Jing Ye Lili Fan Yubang Gao Hangxiao Zhang Lianfeng Gu | 2022 | Journal of Integrative Plant Biology2022，64，3： | 6 |
| 4 | MKRN3 regulates the epigenetic switch of mammalian puberty via ubiquitination of MBD3显示文摘Central precocious puberty(CPP)refers to a human syndrome of early puberty initiation with characteristic increase in hypothalamic production and release of gonadotropin-releasing hormone(GnRH).Previously,loss-of-function mutations in human MKRN3,encoding a putative E3 ubiquitin ligase,were found to contribute to about 30%of cases of familial CPP.MKRN3 was thereby suggested to serve as a‘brake’of mammalian puberty onset,but the underlying mechanisms remain as yet unknown.Here,we report that genetic ablation of Mkrn3 did accelerate mouse puberty onset with increased production of hypothalamic GnRH1.MKRN3 interacts with and ubiquitinates MBD3,which epigenetically silences GNRH1 through disrupting the MBD3 binding to the GNRH1 promoter and recruitment of DNA demethylase TET2.Our findings have thus delineated a molecular mechanism through which the MKRN3-MBD3 axis controls the epigenetic switch in the onset of mammalian puberty. | Chuanyin Li Wenli Lu Liguang Yang Zhengwei Li Xiaoyi Zhou Rong Guo Junqi Wang Zhebao Wu Zhiya Dong Guang Ning Yujiang Shi Yinmin Gu Peng Chen Zijian Hao Tianting Han Meiqiang Yang Wei Wang Xuehui Huang Yixue Li Shan Gao Ronggui Hu | 2020 | National Science Review2020，7，3： | 2 |
| 5 | Temporal Onset of Hypoxia and Oxidative Stress After Pulmonary Irradiation显示文摘 | Katharina Fleckenstein Larisa Zgonjanin Liguang Chen Zahid Rabbani Isabel L. Jackson Bradley Thrasher John Kirkpatrick W. Michael Foster Zeljko Vujaskovic | 2007 | International Journal of Radiation Oncology, Biology, Physics2007，，： | 1 |
| 6 | Soluble TGFβ TYPE II receptor gene therapy ameliorates acute radiation-induced pulmonary injury in rats显示文摘 | Zahid N Rabbani Mitchell S Anscher Xiuwu Zhang Liguang Chen Thaddeus V Samulski Chuan-Yuan Li Zeljko Vujaskovic | 2003 | International Journal of Radiation Oncology, Biology, Physics2003，，2： | 1 |
| 7 | Lithium nitrate regulated carbonate electrolytes for practical Li-metal batteries: Mechanisms, principles and strategies显示文摘Li-metal batteries(LMBs)regain research prominence owing to the ever-increasing high-energy requirements.Commercially available carbonate electrolytes exhibit unfavourable parasitic reactions with Limetal anode(LMA),leading to the formation of unstable solid electrolyte interphase(SEI)and the breed of Li dendrites/dead Li.Significantly,lithium nitrate(LiNO_(3)),an excellent film-forming additive,proves crucial to construct a robust Li_(3)N/Li_(2)O/Li_(x)NO_(y)-rich SEI after combining with ether-based electrolytes.Thus,the given challenge leads to natural ideas which suggest the incorporation of LiNO_(3) into commercial carbonate for practical LMBs.Regrettably,LiNO_(3) demonstrates limited solubility(~800 ppm)in commercial carbonate electrolytes.Thence,developing stable SEI and dendrite-free LMA with the incorporation of LiNO_(3) into carbonate electrolytes is an efficacious strategy to realize robust LMBs via a scalable and cost-effective route.Therefore,this review unravels the grievances between LMA,LiNO_(3)and carbonate electrolytes,and enables a comprehensive analysis of LMA stabilizing mechanism with LiNO_(3),dissolution principle of LiNO_(3) in carbonate electrolytes,and LiNO_(3) introduction strategies.This review converges attention on a point that the LiNO_(3)-introduction into commercial carbonate electrolytes is an imperious choice to realize practical LMBs with commercial 4 V layered cathode. | Kun Wang Wenbing Ni Liguang Wang Lu Gan Jing Zhao Zhengwei Wan Wei Jiang Waqar Ahmad Miaomiao Tian Min Ling Jun Chen Chengdu Liang | 2023 | Journal of Energy Chemistry2023，，2： | 1 |
| 8 | The Real-Time MRI (0.23T Open Scanner) Guidance and Monitoring in Percutaneous Laser Ablation of Liver Primary and Secondary Tumors显示文摘 | Chengli Li Lebin Wu Liguang Chen Hao Shi Zengyu Lin Robert Blanco Sequneir | 2005 | Journal of US-China Medical Science2005，2，4： | 1 |
| 9 | Design and Implementation of an FDP Chip显示文摘 | Chen Liguang Wang Yabin Wu Fang | | 0，，04： | 1 |
| 10 | O _{2}^{\z.rad - }显示文摘 | Isabel L. Jackson Liguang Chen Ines Batinic-Haberle Zeljko Vujaskovic | 2007 | Free Radical Research2007，，1： | 1 |
| 11 | High expression of miR-21 and miR-155 predicts recurrence and unfavourable survival in non-small cell lung cancer显示文摘 | Miaomiao Yang Hongchang Shen Chen Qiu Yang Ni Liguang Wang Wei Dong Yida Liao Jiajun Du | 2012 | European Journal of Cancer2012，，： | 1 |
| 12 | Separation cyclohexene /cyclohexane mixtures with facilitated transport membrane of poly(vinyl alcohol)-Co(Ⅱ) 显示文摘 | Shen Jiangnan Wu Liguang Chen Huanlin | 2005 | Separation and Purification Technology2005，45，2： | 1 |
| 13 | Preparation and pervaporation property of chitosan membrane with functionalized multiwalled carbon nanotubes 显示文摘 | Qiu Shi Wu Liguang Shi Guozhong Zhang Lin Chen Huanlin Gao Congjie | 2010 | Industrial & Engineering Chemistry Research2010，49，11： | 1 |
| 14 | Plate versus intramedullary nail fixation in the treatment of humeral shaft fractures: an updated meta-analysis显示文摘 | Hanbin Ouyang Jun Xiong Peng Xiang Zhuang Cui Liguang Chen Bin Yu | 2012 | Journal of Shoulder and Elbow Surgery2012，，： | 1 |
| 15 | An advanced low-cost cathode composed of graphene-coated Na_(2.4)Fe_(1.8)(SO_(4))_(3) nanograins in a 3D graphene network for ultra-stable sodium storage显示文摘Iron-based electrodes have attracted great attention for sodium storage because of the distinct cost effectiveness.However,exploring suitable iron-based electrodes with high power density and long duration remains a big challenge.Herein,a spray-drying strategy is adopted to construct graphene-coated Na_(2.4)Fe_(1.8)(SO_(4))_(3) nanograins in a 3D graphene microsphere network.The unique structural and compositional advantages endow these electrodes to exhibit outstanding electrochemical properties with remarkable rate performance and long cycle life.Mechanism analyses further explain the outstanding electrochemical properties from the structural aspect. | Yongjin Fang Qi Liu Xiangming Feng Weihua Chen Xinping Ai Liguang Wang Liang Wang Zhiyuan Ma Yang Ren Hanxi YangYuliang Cao | 2021 | Journal of Energy Chemistry2021，30，3： | 0 |
| 16 | Genetic Advances in Genome and Phenotypic Characters of Domestic Dog显示文摘Dogs represent such a rich potential resource to further understand diseases and genetic traits.Comparing the genomes of three species of canine,human,and rat in terms of genome analysis,it is found that dogs are highly conservative with humans and rats.The special population structure of dogs makes it a good model for studying the diversity of morphology and behavior,the genetic basis of mammalian evolution,and dis-eases.This article gives a brief review of recent advances in domestic dog origin and evolution,genomic structure,genetic variation in dog pheno-typic characteristics,and gene mapping.These research results are expected to provide a better theoretical basis for canine genetic breeding re-search and provide new ideas and methods for the prevention,diagnosis and treatment of human diseases. | Li Jing Wan Jiusheng Chen Chao Deng Weidong Yue Rui Xiong Heli Li Liguang | 2020 | Animal Husbandry and Feed Science2020，12，2： | 0 |
| 17 | Circularly Polarized Light-Enabled Chiral Nanomaterials:From Fabrication to Application显示文摘For decades,chiral nanomaterials have been extensively studied because of their extraordinary properties.Chiral nanostructures have attracted a lot of interest because of their potential applications including biosensing,asymmetric catalysis,optical devices,and negative index materials.Circularly polarized light(CPL)is the most attractive source for chirality owing to its high availability,and now it has been used as a chiral source for the preparation of chiral matter.In this review,the recent progress in the field of CPL-enabled chiral nanomaterials is summarized.Firstly,the recent advancements in the fabrication of chiral materials using circularly polarized light are described,focusing on the unique strategies.Secondly,an overview of the potential applications of chiral nanomaterials driven by CPL is provided,with a particular emphasis on biosensing,catalysis,and phototherapy.Finally,a perspective on the challenges in the field of CPL-enabled chiral nanomaterials is given. | Changlong Hao Gaoyang Wang Chen Chen Jun Xu Chuanlai Xu Hua Kuang Liguang Xu | 2023 | Nano-Micro Letters2023，15，3： | 0 |
| 18 | Discovery of novel heteroaryl alkynes for highly potent KIT^(D816V) cells inhibition to treat gastrointestinal stromal tumors显示文摘To the Editor:Gastrointestinal stromal tumors(GIST)is the most popular mesenchymal tumor in the gastrointestinal tract with approximately 80%of GIST harboring gain-of-function mutations at either the extracellular region(exon 9)or the juxtamembrane domain(JMD,exon 11)of KIT,resulting in uncontrolled proliferation and resistance to apotosis1. | Zhicheng Xie Lin Li Yihao Guo Mi Zhang Taiwen Chen Yongpeng Li Xin Li Xi Zhu Yu Zhang Liguang Lou Youhong Hu | 2022 | Acta Pharmaceutica Sinica B2022，12，10： | 0 |
| 19 | Synergistic Effects of Rotavirus and Co-Infecting Viral Enteric Pathogens on Diarrheal Disease-Guangzhou City,Guangdong Province,China,2019显示文摘What is already known about this topic?Diarrhea represents a substantial public health issue,contributing globally to a high number of pediatric medical consultations,hospital admissions,and mortality rates.What is added by this report?An increase in diarrheal frequency serves as a critical benchmark for evaluating severity.The predominant pathogens associated with pediatric diarrhea are rotavirus and norovirus,with co-infections exerting a notable compounding effect that leads to more severe diarrhea.What are the implications for public health practice?Implementing sensitive diagnostic techniques and comprehensive monitoring is paramount in identifying co-infections.Such strategies can provide physicians with critical insights into disease progression,thus considerably reducing the burden of diarrhea. | Shunxian Zhang Liguang Tian Yan Lu Lei Wang Wenwen Lyu Jinxin Zheng Shan Lyu Lili Pang Guobing Yang Hongli Wang Ruitao Liu Guanhua Chen Jichun Wang | 2023 | China CDC weekly2023，5，33： | 0 |
| 20 | A Full Coverage Test Method for Configurable Logic Blocks in FPGA显示文摘 | FU Yong WANG Chi CHEN Liguang LAI Jinmei | 2013 | Chinese Journal of Electronics2013，22，3： | 0 |
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