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| 1 | TET1 is a DNA-binding protein that modulates DNA methylation and gene transcription via hydroxylation of 5-methylcytosine显示文摘 | Haikuo Zhang Xin Zhang Erin Clark Michelle Mulcahey Stephen Huang Yujiang Geno Shi | 2010 | Cell Research2010，20，12： | 20 |
| 2 | State of charge estimation by finite difference extended Kalman filter with HPPC parameters identification显示文摘State of charge(SOC) is a key parameter of lithium-ion battery. In this paper, a finite difference extended Kalman filter(FDEKF)with Hybrid Pulse Power Characterization(HPPC) parameters identification is proposed to estimate the SOC. The finite difference(FD) algorithm is benefit to compute the partial derivative of nonlinear function, which can reduce the linearization error generated by the extended Kalman filter(EKF). The FDEKF algorithm can reduce the computational load of controller in engineering practice without solving the Jacobian matrix. It is simple of dynamic model of lithium-ion battery to adopt a secondorder resistor-capacitor(2 RC) network, the parameters of which are identified by the HPPC. Two conditions, both constant current discharge(CCD) and urban dynamometer driving schedule(UDDS), are utilized to validate the FDEKF algorithm.Comparing convergence rate and accuracy between the FDEKF and the EKF algorithm, it can be seen that the former is a better candidate to estimate the SOC. | HE Lin HU MinKang WEI YuJiang LIU BingJiao SHI Qin | 2020 | Science China(Technological Sciences)2020，63，3： | 11 |
| 3 | Matrix porosity calculation in volcanic and dolomite reservoirs and its application显示文摘矩阵孔计算断裂并且 vuggy 水库例如 volcanics 和捱过的白云石,是着急地需要在记载得好的评估解决的问题之一。在这篇论文,我们首先比较为从有矩阵孔公式的完整的直径流纹岩核心实验的孔计算的一个实验公式通常使用了。我们讨论实验公式的适用性在断裂并且 vuggy 水库,例如中介基本的 volcanics 和捱过的白云石。基于核心分析数据,我们的实验公式的计算的孔的错误分发和在这些水库的公式被给的另外的孔。统计错误分析显示我们的实验公式比另外的孔公式提供更高的精确。当孔在 1.5% 和 15% 之间时,声学的实验公式能不仅为酸的 volcanics 而且在折断的其它和 vuggy 水库被使用,例如中介基本的 volcanics 并且捱过白云石。而且,公式能在孔计算上减少地上凿穿增大和岩石改变的效果。 | Li Ning Wu Hongliang Feng Qingfu Wang Kewen Shi Yujiang Li Qingfeng Luo Xinping | 2009 | Applied Geophysics2009，6，3： | 6 |
| 4 | Histone demethylase LSD1 regulates bone mass by controlling WNT7B and BMP2 signaling in osteoblasts显示文摘Multiple regulatory mechanisms control osteoblast differentiation and function to ensure unperturbed skeletal formation and remodeling. In this study we identify histone lysine-specific demethylase 1(LSD1/KDM1 A) as a key epigenetic regulator of osteoblast differentiation. Knockdown of LSD1 promoted osteoblast differentiation of human mesenchymal stem cells(hMSCs)in vitro and mice lacking LSD1 in mesenchymal cells displayed increased bone mass secondary to accelerated osteoblast differentiation. Mechanistic in vitro studies revealed that LSD1 epigenetically regulates the expression of WNT7 B and BMP2. LSD1 deficiency resulted in increased BMP2 and WNT7 B expression in osteoblasts and enhanced bone formation, while downregulation of WNT7 B-and BMP2-related signaling using genetic mouse model or small-molecule inhibitors attenuated bone phenotype in vivo. Furthermore, the LSD1 inhibitor tranylcypromine(TCP) could increase bone mass in mice. These data identify LSD1 as a novel regulator of osteoblast activity and suggest LSD1 inhibition as a potential therapeutic target for treatment of osteoporosis. | Jun Sun Joerg Ermann Ningning Niu Guang Yan Yang Yang Yujiang Shi Weiguo Zou | 2018 | Bone Research2018，6，3： | 5 |
| 5 | A new strain of Crimean-Congo hemorrhagic fever virus isolated from Xinjiang, China显示文摘Crimean-Congo hemorrhagic fever virus(CCHFV) is a highly pathogenic tick-borne virus with a fatality rate of up to 50% in humans. CCHFV is widely distributed in countries around the world.Outbreaks of CCHFV infection in humans have occurred in prior years in Xinjiang Province, China.Epidemiological surveys have detected CCHFV RNA in ticks and animals; however, few isolates were identified. In this study, we identified and isolated a new CCHFV strain from Hyalomma asiaticum asiaticum ticks collected from north of Tarim Basin in Xinjiang, China. A preliminary investigation of infection and antigens expression of CCHFV was performed in newborn mice. The target tissues for CCHFV replication in newborn mice were identified. The analysis of the phylogenetic relationships with other Chinese strains suggested that diverse genotypes of CCHFV have circulated in Xinjiang for years. These findings provide important insights into our understanding of CCHFV infection and evolution as well as disease prevention and control for local residents. | Rong Guo Shu Shen Yanfang Zhang Junming Shi Zhengyuan Su Dan Liu Jinliang Liu Juan Yang Qiguo Wang Zhihong Hu Yujiang Zhang Fei Deng | 2017 | Virologica Sinica2017，32，1： | 5 |
| 6 | Fluid Property Discrimination in Dolostone Reservoirs Using Well Logs显示文摘The Ordovician Majiagou Formation is one of the main gas-producing strata in the Ordos Basin,China.The identification of hydrocarbon-bearing intervals via conventional well logs is a challenging task.This study describes the litholog of Ma 5(Member 5 of Majiagou Formation)dolostones,and then analyzes the responses of various conventional well logs to the presences of natural gas.The lithology of the gas bearing layers is dominantly of the dolomicrite to fine to medium crystalline dolomite.Natural gas can be produced from the low resistivity layers,and the dry layers are characterized by high resistivities.Neutron-density crossovers are not sensitive to the presences of natural gas.In addition,there are no significant increases in sonic transit times in natural gas bearing layers.NMR(nuclear magnetic resonance)logs,DSI(Dipole Sonic Imager)logs and borehole image logs(XRMI)are introduced to discriminate the fluid property in Majiagou dolostone reservoirs.The gas bearing intervals have broad NMR T2(transverse relaxation time)spectrum with tail distributions as well as large T2gm(T2 logarithmic mean values)values,and the T2 spectrum commonly display polymodal behaviors.In contrast,the dry layers and water layers have low T2gm values and very narrow T2 spectrum without tails.The gas bearing layers are characterized by low Vp/Vs ratios,low Poisson’s ratios and low P-wave impedances,therefore the fluid property can be discriminated using DSI logs,and the interpretation results show good matches with the gas test data.The apparent formation water resistivity(AFWR)spectrum can be derived from XRMI image logs by using the Archie’s formula in the flushed zone.The gas bearing layers have broad apparent formation water resistivity spectrum and tail distributions compared with the dry and water layers,and also the interpretation results from the image logs exhibit good agreement with the gas test data.The fluid property in Majiagou dolostone reservoirs can be discriminated through NMR logs,DSI logs and borehole image logs.This study helps establish a predictable model for fluid property in dolostones,and have implications in dolostone reservoirs with similar geological backgrounds worldwide. | WANG Guiwen LAI Jin LIU Bingchang FAN Zhuoying LIU Shichen SHI Yujiang ZHANG Haitao CHEN Jing | 2020 | Acta Geologica Sinica(English Edition)2020，94，3： | 4 |
| 7 | A Novel Model of Predicting Archie's Cementation Factor from Nuclear Magnetic Resonance(NMR) Logs in Low Permeability Reservoirs显示文摘The resistivity experimental measurements of core samples drilled from low permeability reservoirs of Ordos Basin,Northwest China,illustrate that the cementation factors are not agminate,but vary from 1.335 to 1.749.This leads to a challenge for the estimation of water and hydrocarbon saturation.Based on the analysis of Purcell equation and assumption that rock resistivity is determined by the parallel connection of numerous capillary resistances,a theoretical expression of cementation factor in terms of porosity and permeability is established.Then,cementation factor can be calculated if the parameters of porosity and permeability are determined.In the field application,porosity can be easily obtained by conventional logs.However,it is a tough challenge to estimate permeability due to the strong heterogeneity of low permeability reservoirs.Thus,the Schlumberger Doll Research(SDR)model derived from NMR logs has been proposed to estimate permeability.Based on the analysis of the theoretical expressions of cementation factor and SDR model,a novel cementation factor prediction model,which is relevant to porosity and logarithmic mean of NMR T2spectrum(T2lm),is derived.The advantage of this model is that all the input information can be acquired from NMR logs accurately.In order to confirm the credibility of the novel model,the resistivity and corresponding laboratory NMR measurements of 27 core samples are conducted.The credibility of the model is confirmed by comparing the predicted cementation factors with the core analyzed results.The absolute errors for all core samples are lower than 0.071.Once this model is extended to field application,the accuracy of water and hydrocarbon saturation estimation will be significantly improved. | Liang Wang Zhiqiang Mao Yujiang Shi Qin'e Tao Yumei Cheng Yong Song | 2014 | Journal of Earth Science2014，25，1： | 4 |
| 8 | State of charge estimation by square root cubature particle filter approach with fractional order model of lithium-ion battery显示文摘In this paper, a square root cubature particle filter approach was designed to estimate the state of charge of lithium-ion battery,which not only enhanced the numerical stability and guaranteed positive definiteness of the state covariance, but also increased accuracy and decreased computation quantity. Due to the fractional characteristics of the battery capacitance, a fractional order model was used to formulate the lithium-ion battery. Considering the high accuracy and easy convergence, a particle swarm optimization algorithm was utilized to identify the model parameters. The above-mentioned approach was modelled and translated into C code, which was downloaded into battery control unit of battery management system for experimental validation. Two kinds of dynamic cycles were utilized to validate the proposed approach at different temperatures, where both unscent Kalman filter and cubature Kalman filter were compared with the proposed approach. Experimental results indicate that the proposed approach has better accuracy and robustness, and fractional order model is more accurate than integer order model.Therefore, the square root cubature particle filter with fractional order model of lithium-ion battery is a good candidate to estimate the state of charge. | LIU YiWen SHI Qin WEI YuJiang HE ZeJia HU XiaoSong HE Lin | 2022 | Science China(Technological Sciences)2022，65，8： | 2 |
| 9 | Smad5 acts as an intracellular pH messenger and maintains bioenergetic homeostasis显示文摘环境暗示和细胞内部的 bioenergetic 状态深刻地影响细胞内部的 pH (pHi ) 。一个房间怎么对 pHi 变化作出回应维持 bioenergetic 动态平衡,留下逃犯。这里,我们显示出那 Smad5,发信号的形态基因的蛋白质(BMP ) 回答到 pHi 的骨头的一个描绘得好的下游的部件变化。冷、基本或张力亢进的条件增加 pHi,它接着在 Smad5 的 MH1 域以内声言不赞成控告的氨基酸簇,推动它到细胞质的从原子核的重定位。在另一方面,加热,酸或张力减退的条件减少 pHi,堵住 Smad5 的原子出口,并且因此引起它的原子累积。环境变化和 pHi 变化导致的 Smad5 的活跃 nucleocytoplasmic shuttling 独立于 BMP 发信号, carboxyl 终点 phosphorylation 和 Smad4。另外, Smad5 的脱离引起在区别识别了的神经发展过程人的 pluripotent 干细胞建模的细胞的 bioenergetic 动态平衡和破坏正常的长期、不可逆的 dysregulation。重要地,在 Smad5 缺乏的房间的这些新陈代谢、发展的赤字能仅仅由细胞质的 Smad5 被救。细胞质的 Smad5 身体上与 hexokinase 交往 1 并且加速 glycolysis。一起,我们的调查结果显示 Smad5 充当一个 pHi 送信人并且由调整细胞质的新陈代谢的机械维持房间的 bioenergetic 动态平衡。 | Yujiang Fang Zhongliang Liu Zhenyu Chen Xiangjie Xu Mengtao Xiao Yanyan Yu Yuanyuan Zhang Xiaobai Zhang Yanhua Du Cizhong Jiang Yuzheng Zhao Yiran Wang Beibei Fan Daniel Terheyden-Keighley Yang Liu Lei Shi Yi Hui Xin Zhang Bowen Zhang Hexi Feng Lin Ma Quanbin Zhang Guohua Jin Yi Yang Bin Xiang Ling Liu Xiaoqing Zhang | 2017 | Cell Research2017，27，9： | 2 |
| 10 | A Fuzzy-based Sliding Mode Control Approach for Acceleration Slip Regulation of Battery Electric Vehicle显示文摘Due to quick response and large quantity of electric motor torque,the traction wheels of battery electric vehicle are easy to slip during the initial phase of starting.In this paper,a sliding mode control approach of acceleration slip regulation is designed to prevent the slip of the traction wheels.The wheel slip ratio is used as the state variable for the formulation of system dynamics model.The fuzzy algorithm is utilized to adjust the switch function of sliding mode controller.After stability and robustness analysis,the sliding mode control law is transferred into C code and downloaded into vehicle control unit,which is validated under wet and dry road conditions.The experimental results with a small overshoot and a quick response during starting indicate that the sliding mode controller has good control efect on the slip ratio regulation.This article proposes an acceleration slip regulation method that improves the safety during acceleration for battery electric vehicle. | Qin Shi Mingwei Wang Zejia He Cheng Yao Yujiang Wei Lin He | 2022 | Chinese Journal of Mechanical Engineering2022，35，4： | 2 |
| 11 | MKRN3 regulates the epigenetic switch of mammalian puberty via ubiquitination of MBD3显示文摘Central precocious puberty(CPP)refers to a human syndrome of early puberty initiation with characteristic increase in hypothalamic production and release of gonadotropin-releasing hormone(GnRH).Previously,loss-of-function mutations in human MKRN3,encoding a putative E3 ubiquitin ligase,were found to contribute to about 30%of cases of familial CPP.MKRN3 was thereby suggested to serve as a‘brake’of mammalian puberty onset,but the underlying mechanisms remain as yet unknown.Here,we report that genetic ablation of Mkrn3 did accelerate mouse puberty onset with increased production of hypothalamic GnRH1.MKRN3 interacts with and ubiquitinates MBD3,which epigenetically silences GNRH1 through disrupting the MBD3 binding to the GNRH1 promoter and recruitment of DNA demethylase TET2.Our findings have thus delineated a molecular mechanism through which the MKRN3-MBD3 axis controls the epigenetic switch in the onset of mammalian puberty. | Chuanyin Li Wenli Lu Liguang Yang Zhengwei Li Xiaoyi Zhou Rong Guo Junqi Wang Zhebao Wu Zhiya Dong Guang Ning Yujiang Shi Yinmin Gu Peng Chen Zijian Hao Tianting Han Meiqiang Yang Wei Wang Xuehui Huang Yixue Li Shan Gao Ronggui Hu | 2020 | National Science Review2020，7，3： | 2 |
| 12 | Histone Demethylation Mediated by the Nuclear Amine Oxidase Homolog LSD1显示文摘 | Yujiang Shi Fei Lan Caitlin Matson Peter Mulligan Johnathan R. Whetstine Philip A. Cole Robert A. Casero Yang Shi | 2004 | Cell2004，，7： | 2 |
| 13 | Assessment of strong earthquake risk in the Chinese mainland from 2021 to 2030显示文摘The long-term earthquake prediction from 2021 to 2030 is carried out by researching the active tectonic block boundary zones in the Chinese mainland.Based on the strong earthquake recurrence model,the cumulative probability of each target fault in the next 10 years is given by the recurrence period and elapsed time of each fault,which are adopted from relevant studies such as seismological geology,geodesy,and historical earthquake records.Based on the long-term predictions of large earthquakes throughout the world,this paper proposes a comprehensive judgment scheme based on the fault segments with the seismic gap,motion strongly locked,sparse small-moderate earthquakes,and apparent Coulomb stress increase.This paper presents a comprehensive analysis of the relative risk for strong earthquakes that may occur in the coming 10 years on the major faults in the active tectonic block boundary zones in the Chinese mainland.The present loading rate of each fault is first constrained by geodetic observations;the cumulative displacement of each fault is then estimated by the elapsed time since the most recent strong earthquake. | Zhigang Shao Yanqiang Wu Lingyun Ji Faqi Diao Fuqiang Shi Yujiang Li Feng Long Hui Zhang Wuxing Wang Wenxin Wei Peng Wang Xiaoxia Liu Qi Liu Zhengyang Pan Xiaofei Yin Yue Liu Wei Feng Zhenyu Zou Jia Cheng Renqi Lu Yueren Xu Xi Li | 2023 | Earthquake Research Advances2023，3，1： | 2 |
| 14 | Structural insight into substrate recognition by histone demethylase LSD2/KDM1 b显示文摘 | Fei Chen Huirong Yang Zhenghong Dong Jian Fang Ping Wang Tingting Zhu Wei Gong Rui Fang Yujiang Geno Shi Ze Li Yanhui Xu | 2013 | Cell Research2013，23，2： | 2 |
| 15 | Histone Demethylation Mediated by the Nuclear Amine Oxidase Homolog显示文摘 | Yujiang Shi Fei Lan Caitlin Matson | 2004 | LSDI Cell2004，119，： | 1 |
| 16 | Histone demethylation mediated by the nuclear amine oxidase homolog LSD1显示文摘 | Yujiang Shi Fei Lan Caitlin Matson | 2004 | Cell2004，119，7： | 1 |
| 17 | A New Empirical Method for Constructing Capillary Pressure Curves from Conventional Logs in Low-Permeability Sandstones显示文摘Pore structure reflected from capillary pressure curves plays an important role in low-permeability formation evaluation. It is a common way to construct capillary pressure curves by Nuclear Magnetic Resonance(NMR) log. However, the method's efficiency will be severely affected if there is no NMR log data or it cannot reflect pore structure well. Therefore, on the basis of J function and diagenetic facies classification, a new empirical model for constructing capillary pressure curves from conventional logs is proposed here as a solution to the problem. This model includes porosity and the relative value of natural gamma rays as independent variables and the saturation of mercury injection as a dependent variable. According to the 51 core experimental data sets of three diagenetic facies from the bottom of the Upper Triassic in the western Ordos Basin, China, the model's parameters in each diagenetic facies are calibrated. Both self-checking and extrapolation tests show a positive effect, which demonstrates the high reliability of the proposed capillary pressure curve construction model. Based on the constructed capillary pressure curves, NMR T_2 spectra under fully brine-saturated conditions are mapped by a piecewise power function. A field study is then presented. Agreement can be seen between the mapped NMR T_2 spectra and the MRIL-Plog data in the location of the major peak, right boundary, distribution characteristics and T_2 logarithmic mean value. In addition, the capillary pressure curve construction model proposed in this paper is not affected by special log data or formation condition. It is of great importance in evaluating pore structure, predicting oil production and identifying oil layers through NMR log data in low-permeability sandstones. | Cheng Feng Yujiang Shi Jiahong Li Liang Chang Gaoren Li Zhiqiang Mao | 2017 | Journal of Earth Science2017，28，3： | 1 |
| 18 | Characterization and fine mapping of the glabrous leaf and hull mutants (gl1) in rice (Oryza sativa L.)显示文摘 | Wenqiang Li Jianguo Wu Shili Weng Dapeng Zhang Yujiang Zhang Chunhai Shi | 2010 | Plant Cell Reports2010，，6： | 1 |
| 19 | Risk Factors for Syphilis and Prevalence of HIV, Hepatitis B and C among Men Who Have Sex with Men in Beijing, China: Implications for HIV Prevention显示文摘 | Yuhua Ruan Fengji Luo Yujiang Jia Xinxu Li Qingchun Li Hongyuan Liang Xiaoxi Zhang Dongliang Li Wei Shi Jennifer M. Freeman Sten H. Vermund Yiming Shao | 2009 | AIDS and Behavior2009，，： | 1 |
| 20 | Histone Demethylation Mediated by the Nuclear Amine Oxidase Homolog LSD1显示文摘 | Yujiang Shi Fei Lan Caitlin Matson Peter Mulligan Johnathan R. Whetstine Philip A. Cole Robert A. Casero Yang Shi | 2004 | Cell2004，，7： | 1 |
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