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1Mycorrhizal symbiosis modulates the rhizosphere microbiota to promote rhizobia–legume symbiosis显示文摘Plants establish symbioses with mutualistic fungi,such as arbuscular mycorrhizal(AM)fungi,and bacteria,such as rhizobia,to exchange key nutrients and thrive.Plants and symbionts have coevolved and represent vital components of terrestrial ecosystems.Plants employ an ancestral AM signaling pathway to establish intracellular symbioses,including the legume–rhizobia symbiosis,in their roots.Nevertheless,the relationship between the AM and rhizobial symbioses in native soil is poorly understood.Here,we examined how these distinct symbioses affect root-associated bacterial communities in Medicago truncatula by performing quantitative microbiota profiling(QMP)of 16S rRNA genes.We found that M.truncatula mutants that cannot establish AM or rhizobia symbiosis have an altered microbial load(quantitative abundance)in the rhizosphere and roots,and in particular that AM symbiosis is required to assemble a normal quantitative root-associated microbiota in native soil.Moreover,quantitative microbial co-abundance network analyses revealed that AM symbiosis affects Rhizobiales hubs among plant microbiota and benefits the plant holobiont.Through QMP of rhizobial rpoB and AM fungal SSU rRNA genes,we revealed a new layer of interaction whereby AM symbiosis promotes rhizobia accumulation in the rhizosphere of M.truncatula.We further showed that AM symbiosis-conditioned microbial communities within the M.truncatula rhizosphere could promote nodulation in different legume plants in native soil.Given that the AM and rhizobial symbioses are critical for crop growth,our findings might inform strategies to improve agricultural management.Moreover,our work sheds light on the co-evolution of these intracellular symbioses during plant adaptation to native soil conditions.Xiaolin Wang Huan Feng Yayu Wang Mingxing Wang Xingguang Xie Huizhong Chang Like Wang Jicheng Qu Kai Sun Wei He Chunyan Wang Chuanchao Dai Zhaohui Chu Changfu Tian Nan Yu Xuebin Zhang Huan Liu Ertao Wang 2021Molecular Plant2021,14,3:6
2Cryogenic treatment induced hardening for Cu-Zr-Ag-Al bulk metallic glasses显示文摘Little is known about the mechanical properties of bulk metallic glassy alloys(BMGs) after cryogenic treatment.In this study,the effects of cryogenic treatment(CT) on the microstructural transition and the mechanical properties of Cu-based bulk metallic glass(BMG) were studied.The results showed that submicron AlCu2Zr and Cu5Zr phases can precipitate from the Cu-Zr-Ag-Al matrix after 192 h CT.The formation of these nanometer-sized crystalline phases substantially enhanced the mechanical properties of the bulk amorphous alloy.The micro-hardness and the compressive strength were found to increase respectively from 501 HV and 1510 MPa to 595 HV and 1910 MPa after cryogenic treatment.CT is a promising approach to strengthening metal glasses.CHEN ZhenHua ZHANG LiKe LIU JiZi CHEN Ding 2013Chinese Science Bulletin2013,58,7:5
3Cell viability and dopamine secretion of 6-hydroxydopamine-treated PC12 cells co-cultured with bone marrow-derived mesenchymal stem cells显示文摘In the present study, PC12 cells induced by 6-hydroxydopamine as a model of Parkinson's Disease, were used to investigate the protective effects of bone marrow-derived mesenchymal stem cells bone marrow-derived mesenchymal stem cells against 6-hydroxydopamine-induced neurotoxicity and to verify whether the mechanism of action relates to abnormal α-synuclein accumulation in cells. Results showed that co-culture with bone marrow-derived mesenchymal stem cells enhanced PC12 cell viability and dopamine secretion in a cell dose-dependent manner. MitoLight staining was used to confirm that PC12 cells co-cultured with bone marrow-derived mesenchymal stem cells demonstrate reduced levels of cell apoptosis. Immunocytochemistry and western blot analysis found the quantity of α-synuclein accumulation was significantly reduced in PC12 cell and bone marrow-derived mesenchymal stem cell co-cultures. These results indicate that bone marrow-derived mesenchymal stem cells can attenuate 6-hydroxydopamine-induced cytotoxicity by reducing abnormal α-synuclein accumulation in PC12 cells.Yue Tang Yongchun Cui Fuliang Luo Xiaopeng Liu Xiaojuan Wang Aili Wu Junwei Zhao Zhong Tian Like Wu 2012Neural Regeneration Research2012,7,14:3
4Design and validation of the THMC China-Mock-Up test on buffer material for HLW disposal显示文摘According to the preliminary concept of the high-level radioactive waste(HLW) repository in China,a large-scale mock-up facility,named China-Mock-Up was constructed in the laboratory of Beijing Research Institute of Uranium Geology(BRIUG).A heater,which simulates a container of radioactive waste,is placed inside the compacted Gaomiaozi(CMZ)-Na-bentonite blocks and pellets.Water inflow through the barrier from its outer surface is used to simulate the intake of groundwater.The numbers of water injection pipes,injection pressure and the insulation layer were determined based on the numerical modeling simulations.The current experimental data of the facility are herein analyzed.The experiment is intended to evaluate the thermo-hydro-mechano-chemical(THMC) processes occurring in the compacted bentonite-buffer during the early stage of HLW disposal and to provide a reliable database for numerical modeling and further investigation of engineered barrier system(EBS),and the design of HLW repository.Yuemiao Liu Like Ma Dan Ke Shengfei Cao Jingli Xie Xingguang Zhao Liang Chena Panpan Zhang 2014Journal of Rock Mechanics and Geotechnical Engineering2014,6,2:2
5Composition, characteristics and development of advanced ceramic cutting tools显示文摘Li Xikun Liu Jing Qiu Like 2007Journal of Rare Earths2007,25,2:1
6SJES14110700417215显示文摘Jiachen Wang Shengli Yang Yang Li Like Wei Haohao Liu 2014International Journal of Rock Mechanics and Mining Sciences2014,,:1
7Improving aircraft aerodynamic performance with bionic wing obtained by ice shape modulation显示文摘For Unmanned Aerial Vehicles(UAVs)with limited electrical power to achieve effectively anti-/de-icing at the leading edge of the wing,a strategy of ice shape modulation was proposed.Isolated simulated ice shape pieces printed by 3D printing technology are mounted on a NACA0012 finite wing model,and its lift/drag coefficients and suction-side velocity fields are measured by the six-component force balance and the Particle Imaging Velocimetry(PIV),respectively.The ratio of the spanwise length of a single ice shape piece to chord length and the spanwise length of the non-icing area between the two adjacent single ice shape pieces are defined as dimensionless ice shape length(w/c)and dimensionless modulation ratio(w/λ),respectively.The results indicate that for a fixed w/λ,the wing lift coefficient first increases and then drops with increasing w/c,and a peak value exists when w/c is between 0.1 and 0.2.The lower the w/λis,the higher the wing lift coefficient will be.The periodical variation of the flow separation area along the spanwise direction is attributed on the one hand to the acceleration effect of the flow field in the non-icing area which reduces the separation area,and on the other hand to the cross-flow caused by the streamwise vortices from the non-icing area to the icing area which promotes the mixing of the flow field(similar to vortex generators).The obtained modulation law is verified through flight tests and provides guidance for the use of ice shape modulation scheme for UAVs that cannot be completely anti-/deicing under severe weather conditions.Like XIE Hua LIANG Haohua ZONG Yun WU Yinghong LI Zhi SU Xuecheng LIU 2023Chinese Journal of Aeronautics2023,36,2:1
8Minimizing airfoil drag at low angles of attack with DBD-based turbulent drag reduction methods显示文摘Dielectric Barrier Discharge(DBD)based turbulent drag reduction methods are used to reduce the total drag on a NACA 0012 airfoil at low angels of attack.The interaction of DBD with turbulent boundary layer was investigated,based on which the drag reduction experiments were conducted.The results show that unidirectional steady discharge is more effective than oscillating discharge in terms of drag reduction,while steady impinging discharge fails to finish the mission(i.e.drag increase).In the best scenario,a maximum relative drag reduction as high as 64%is achieved at the freestream velocity of 5 m/s,and a drag reduction of 13.7%keeps existing at the freestream velocity of 20 m/s.For unidirectional discharge,the jet velocity ratio and the dimensionless actuator spacing are the two key parameters affecting the effectiveness.The drag reduction magnitude varies inversely with the dimensionless spacing,and a threshold value of the dimensionless actuator spac-ing of 540(approximately five times of the low-speed streak spacing)exists,above which the drag increases.When the jet velocity ratio smaller than 0.05,marginal drag variation is observed.In con-trast,when the jet velocity ratio larger than 0.05,the experimental data bifurcates,one into the drag increase zone and the other into the drag reduction zone,depending on the value of dimensionless actuator spacing.In both zones,the drag variation magnitude increases with the jet velocity ratio.The total drag reduction can be divided into the reduction in pressure drag and turbulent friction drag,as well as the increase in friction drag brought by transition promotion.The reduction in tur-bulent friction drag plays an important role in the total drag reduction.Zhi SU Haohua ZONG Hua LIANG Jun LI Like XIE Xuecheng LIU Weiliang KONG Borui ZHENG 2023Chinese Journal of Aeronautics2023,36,4:1
9The Modular Configura- tion System Based on Case-Based Reasoning 显示文摘Liu Changchun Shen Zhongqi Wu Like 2012Journal of Ad- vanced Manufacturing Systems2012,11,2:1
10High-entropy alloys and compounds for electrocatalytic energy conversion applications显示文摘High-entropy materials,composed of five or more elements in near-equiatomic percentage,have been attracting tremendous interests due to their advantageous properties in a variety of applications.Recently,electrocatalysis on high-entropy alloys(HEAs)and high-entropy compounds(HECs)has emerged as a new and promising material owing to the tailored composition and the disordered con-figuration of HEAs and HECs.Though extensive efforts have been devoted to investigating the catalytic nature of HEAs and HECs,the details related to the active sites and intrinsic activity of such catalysts still remain uncertain due to the complexity of the multicomponent systems.In this review,the recent progress of HEAs and HECs is systematically reviewed in terms of their synthetic strate-gies and electrocatalytic applications.Importantly,the computationally assisted methods(e.g.,density functional theory[DFT])are also presented to discover and design the optimumHEA-andHEC-based catalysts.Subsequently,the appli-cations of HEAs and HECs in electrocatalytic energy conversion reactions will be discussed,including hydrogen evolution reaction,oxygen evolution reaction,oxygen reduction reaction,carbon dioxide reduction reaction,nitrogen reduction reaction,methanol oxidation reaction,and ethanol oxidation reaction(EOR).Moreover,the prospects and future opportunities for this research field are cau-tiously discussed.A series of upcoming challenges and questions are thoroughly proposed from the experimental and theoretical aspects as well as other future applications in electrocatalysis.Hang Liu Lenus Syama Like Zhang Carmen Lee Chuntai Liu Zhengfei Dai Qingyu Yan 2021SusMat2021,1,4:1
11Genetic diversity of wheat gene pool of recurrent selection assessed by mierosatel lite markers and morphological traits 显示文摘Jiancheng Liu Like Liu Ning Hou 2007Euphytica2007,155,:1
12微捷码软件应用于高性能并行计算系统中复杂交换芯片的物理实现显示文摘本文主要介绍了面向并行计算系统互连应用的复杂交换芯片(Switch ASIC)的芯片结构、设计权衡和物理实现。该交换芯片通过集成3路16x16交叉开关和特别垫垒处理单元,不仅可支持具有高吞吐量和低延迟的多层多功能包交换,而且还在其16个RX/TX端口间提供了先进的全局垫垒处理加速功能;以156.25MHz频率运行,拥有80Gbps端口交换和240Gbps内部包交换容量以及3.12Gbps的端口吞吐量。通过对一些芯片路径多模多角下时序的仔细调整以及对输出片上时钟网络的OCV优化,以微捷码的Blast工具为主达成了4种功能模式、3个PVT角点下芯片物理实现的完全时序收敛。目前,该芯片已通过0.18μm/6Metal CMOS技术完成投片,拥有约2000万个晶体管、17个不同的时钟域、48个RAM宏块、12.39mmx12.39mm芯片尺寸以及1053个引脚倒装芯片封装。Hua Shen Dingshan You Xiaoxiao Jiang Like Liu Jia Yang Rongrong Quo 2009中国集成电路2009,18,9:0
13TiO_(2)-supported Single-atom Catalysts:Synthesis,Structure,and Application显示文摘In recent years,single-atom catalysts(SACs)have attracted increasing attention in catalysis.However,their stability is considerably challenging.As a result,fine-tuning the interaction of metal single atoms(SA)with different types of supports has emerged as an effective strategy for improving their thermal and chemical stabilities.Owing to its non-toxicity,cost-effectiveness,high abundance,and excellent stability,as well as presence of rich,tunable,and reliable anchor sites for metal SA,TiO_(2)has been extensively explored as a superior support for SACs.In this review,recent advances of TiO_(2)-supported SACs(M1/TiO_(2))are discussed,and synthetic strategies,structure elucidation,and catalytic applications are summarized.First,the recently developed synthetic strategies for M1/TiO_(2)arehighlighted and summarized,identifying the major challenges for the precise fabrication of M1/TiO_(2).Subsequently,key characterization techniques for the structure identification of M1/TiO_(2)are discussed.Next,catalytic applications of M1/TiO_(2)are highlighted,viz.photocatalysis,electrocatalysis,and thermocatalysis.In addition,the mechanism via geometric structures and electronic states of metal centers facilitate catalytic reactions is outlined.Finally,opportunities and challenges of M1/TiO_(2)in catalysis are discussed,which may inspire the future development of M1/TiO_(2)for multifunctional catalytic applications.LIU Zailun SUN Like ZHANG Qitao TENG Zhenyuan SUN Hongli SU Chenliang 2022Chemical Research in Chinese Universities2022,38,5:0
14A universal tactic of using Lewis-base polymer-CNTs composites as additives for high performance cm2-sized and flexible perovskite solar cells显示文摘Lewis-base polymers have been widely utilized as additives to act as a template for the perovskite nucleation/crystal growth and passivate the under-coordinated Pb2+ sites.However,it is uncovered in this work that the polymer on the perovskite grain boundaries would significantly hinder the charge transport due to its low conductivity,which brings about free carrier recombination and photocurrent losses.To circumvent this issue while fully exploiting the benefits of polymers in passivating the trap states in perovskite,we incorporate highly conductive multiwall carbon nanotubes(CNTs) with Lewis-base polymers as coadditives in the perovskite film.Functionalizing the CNTs with-COOH group enables a selective hole-extraction and charge transport from perovskite to the hole transporting materials(HTM).By studying the charge transporting and recombination dynamics,we revealed the individual role of the polymer and CNTs in passivating the trap states and facilitating the charge transport,respectively.As a result,the perovskite solar cells(PSCs) with polymer-CNTs composites exhibit an impressive PCE of 21.7% for a small-area device(0.16 cm2) and 20.7% for a large-area device(1.0 cm2).Moreover,due to the superior mechanical flexibility of both polymer and CNTs,the polymer-CNTs composites incorporation in the perovskite film encourages the fabrication of flexible PSCs(f-PSCs) with an impressive PCE of 18.3%,and a strong mechanical durability by retaining 80%of the initial PCE after 1,000 times bending.In addition,we proved that the selection criteria of the polymers can be extended to other long-chain Lewis-base polymers,which opens new possibilities in design and synthesis of inexpensive material for this tactic towards the fabrication of high performance large-area PSCs and f-PSCs.Chang Liu Jingsong Sun Xiao-Fang Jiang Like Huang Qiang Lou Yi-Bing Cheng Shulin Song Ziyi Ge 2021Science China Chemistry2021,64,2:0
15A Comparative Toxicity Study of TiO2 Nanoparticles in Suspension and Adherent Culture Under the Dark Condition显示文摘CHEN Like LIU Miao LENG Su LI Zhuan 2018Chemical Research in Chinese Universities2018,34,1:0
16Aiphanol, a native compound, suppresses angiogenesis via dual-targeting VEGFR2 and C0X2显示文摘Dear Editor,Pathological neo-vascularization is a hallmark of cancer and several diseases.Accumulating evidence supports the notion that antiangiogenic treatment can abolish tumor angiogenesis to achieve Ion ger disease-free survival.Although growth factors and their receptors function as the main drivers in angiogenesis,the involvement of other regulators,e.g.,Cyclooxygenase-2(COX2),^(1) should also be con sidered,especially for managi ng the resista nee to therapies against receptor tyrosine kinases(RTKs).Shanmei Chen Junnan Feng Chuanke Zhao Lixin Wang Lin Meng Caiyun Liu Shaoqing Cai Yanxing Jia Like Qu Chengchao Shou 2022Signal Transduction and Targeted Therapy2022,7,1:0
17Data-driven Reactive Power Optimization for Distribution Networks Using Capsule Networks显示文摘The construction of advanced metering infrastructure and the rapid evolution of artificial intelligence bring opportunities to quickly searching for the optimal dispatching strategy for reactive power optimization. This can be realized by mining existing prior knowledge and massive data without explicitly constructing physical models. Therefore, a novel datadriven approach is proposed for reactive power optimization of distribution networks using capsule networks(CapsNet). The convolutional layers with strong feature extraction ability are used to project the power loads to the feature space to realize the automatic extraction of key features. Furthermore, the complex relationship between input features and dispatching strategies is captured accurately by capsule layers. The back propagation algorithm is utilized to complete the training process of the CapsNet. Case studies show that the accuracy and robustness of the CapsNet are better than those of popular baselines(e.g.,convolutional neural network, multi-layer perceptron, and casebased reasoning). Besides, the computing time is much lower than that of traditional heuristic methods such as genetic algorithm, which can meet the real-time demand of reactive power optimization in distribution networks.Wenlong Liao Jiejing Chen Qi Liu Ruijin Zhu Like Song Zhe Yang 2022Journal of Modern Power Systems and Clean Energy2022,10,5:0
18Enhancement of photoelectric performance for CsPbI2Br solar cells by the synergistic effect of binary additives显示文摘CsPbI_(2)Br-based perovskite solar cells(PSCs)have attracted much attention because of their excellent phase stability and appropriate bandgap.However,numerous defects of undercoordinated ions or mobile species are the sites of carrier nonradiative recombination,causing a low power conversion efficiency(PCE).In this work,NaCl and nitrogen-doped graphene quantum dots(N-GQDs)as binary additives are introduced into perovskite precursor to obtain high-quality photoactive films.Chloride ion(Cl^(-))is incorporated into perovskite due to the same physical and chemical properties as bromine(Br^(-)),that align the energy level of CsPbI_(2)Br,decrease the energy barrier between perovskite and P3HT to promote carrier transport and extraction,hence result in the reduced energy loss.Meanwhile,because of its good conductivity,N-GQDs at grain boundaries can rapidly conduct photogenerated electrons to SnO_(2),suppressing carrier recombination at grain boundaries.Furthermore,the trap state density of the CsPbI_(2)Br film with binary additives is reduced,which could prolong the carrier lifetime,and improve surface morphology.As a result,a PCE of 15.37%for CsPbI_(2)Br PSCs with binary additives is obtained,which shows~22.76%relative increment compare with the pristine PSCs.Therefore,a simple and convenient optimization strategy of binary additives for PSCs is proposed in this work.Qiulu Chen Like Lin Yanzhou Wang Zhe Gao Yujun Fu Qiming Liu Junshuai Li Deyan He 2023Journal of Materiomics2023,9,1:0
19Development of plant cytosine base editors with the Cas12a system显示文摘Base editors of the Cas9 system have been widely used for precise nucleotide substitution in crops. In this study, Cas12a was applied to construct plant cytosine base editors(CBEs). The main elements of Cas12aCBEs were engineered and their efficiency was evaluated in stably transformed rice cells. An optimized ttCas12a-hyA3Bctd editor, consisting of a LbCas12a variant carrying catalytic inactive D832A and temperature-tolerance D156R double mutations, a truncated human APOBEC3B deaminase, a human RAD51 single-stranded DNA-binding domain, and double copies of UGI, outperformed other Cas12aCBEs in base editing efficiency. In T0transgenic rice plants, ttCas12a-hyA3Bctd edited an average of42.01% and a maximum of 68.75% of lines at six genomic targets. A-to-G conversions were generated in rice by an adenine base editor with a similar architecture to the optimized CBE. Our results provide preliminary evidence for the feasibility of robust and efficient plant Cas12a base editing systems, which could be useful for precise crop breeding.Huanhuan Wang Jing Liang Like Chen Bufang Deng Dongfang Gu Xiaoshuang Liu Shan Jin Rongfang Xu Ruiying Qin Yitong Zhu Liangxia Zhao Dourong Kou Yanjun Chen Yingli Jiang Juan Li Pengcheng Wei 2023The Crop Journal2023,11,5:0
20Correction: Aiphanol, a native compound, suppresses angiogenesis via dual-targeting VEGFR2 and COX2显示文摘Correction to:Signal Transduction and Targeted Therapy http://gffzzd3cc09b8251d45dfskk6puqbvnp696qxq.ffgz.tsg.suse.edu.cn/10.1038/s41392-021-00739-5,published online 03 December 2021 After online publication of the letter1,the author found two images in the supplement materials were used incorrectly,Additionally,there is an error in the chemical structure of Aiphanol in Figs.1a and 1s that needs to be corrected.The correct data are provided as follows.The key findings of the article are not affected by these corrections.The original article has been corrected.Shanmei Chen Junnan Feng Chuanke Zhao Lixin Wang Lin Meng Caiyun Liu Shaoqing Cai Yanxing Jia Like Qu Chengchao Shou 2022Signal Transduction and Targeted Therapy2022,7,5:0
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