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| 1 | Dek35 Encodes a PPR Protein that Affects cis-Splicing of Mitochondrial nad4 Intron 1 and Seed Development in Maize显示文摘 | Xinze Chen Fan Feng Weiwei Qi Liming xu Dongsheng Yao Qun Wang Rentao Song | 2017 | Molecular Plant2017，10，3： | 24 |
| 2 | Secretory/releasing proteome-based identification of plasma biomarkers in HBV-associated hepatocellular carcinoma显示文摘For successful therapy, hepatocellular carcinoma (HCC) must be detected at an early stage. Herein, we used a proteomic approach to analyze the secretory/releasing proteome of HCC tissues to identify plasma biomarkers. Serum-free conditioned media (CM) were collected from primary cultures of cancerous tissues and surrounding noncancerous tissues. Proteomic analysis of the CM proteins permitted the identification of 1365 proteins. The enriched molecular functions and biological processes of the CM proteins, such as hydrolase activity and catabolic processes, were consistent with the liver being the most important metabolic organ. Moreover, 19% of the proteins were characterized as extracellular or membrane-bound. For validation, secretory proteins involved in transforming growth factor-β signaling pathways were validated in plasma samples. Alphafetoprotein (AFP), metalloproteinase (MMP)1, osteopontin (OPN), and pregnancy-specific beta-1-glycoprotein (PSG)9 were significantly increased in HCC patients. The overall performance of MMP1 and OPN in the diagnosis of HCC remained greater than that of AFP. In addition, this study represents the first report of MMP1 as a biomarker with a higher sensitivity and specificity than AFP. Thus, this study provides a valuable resource of the HCC secretome with the potential to investigate serological biomarkers. MMP1 and OPN could be used as novel biomarkers for the early detection of HCC and to improve the sensitivity of biomarkers compared with AFP. | YANG Lei RONG WeiQi XIAO Ting ZHANG Ying XU Bin LIU Yu WANG LiMing WU Fan QI Jun ZHAO XiuYing WANG HongXia HAN NaiJun GUO SuPing WU JianXiong GAO YanNing CHENG ShuJun | 2013 | Science China(Life Sciences)2013，56，7： | 9 |
| 3 | Development of an automatic calibration device for high-accuracy low temperature thermometers显示文摘Based on the analysis and investigation of calibration systems for high-accuracy low temperature thermometers,a new facility for automatic calibration of high-accuracy low temperature thermometers was developed.Continuous calibration for multiple points can be made automatically with this device.According to the thermophysical characteristics of the constant-temperature block in this device,segmented Fuzzy-PID (proportional-integral-differential) algorithm was applied.The experimental results showed that the temperature fluctuation was smaller than ±0.005 K in 30 min.Therefore,this new device can fully meet the calibration requirement of high-precision low temperature thermometers. | CHEN GuangMing,GAO Xu,ZHANG ShaoZhi,CHEN Qi,TANG LiMing & LAN YuQi Institute of Refrigeration and Cryogenics,Zhejiang University,Hangzhou 310027,China | 2010 | Science China(Technological Sciences)2010，53，9： | 6 |
| 4 | Chemiluminescence and electrochemiluminescence applications of metal nanoclusters显示文摘Due to strong photoluminescence,extraordinary photostability,excellent biocompatibility,and good water-solubility,metal nanoclusters have attracted enormous attention since discovered.They are found to be novel fluorescence labels for biological applications and environmental monitoring.Recently the chemiluminescence(CL) or electrochemiluminescence(ECL) of metal nanoclusters has received increasing attention.This review covers recent vibrant developments in this field of the past 5 years,and highlights different functions of metal nanoclusters in various CL and ECL systems,such as luminophores,catalysts,and quenchers.Latest synthetic methods of metal nanoclusters used in CL or ECL are also summarized.Furthermore,we discuss some perspectives and critical challenges of this field in the near future. | Shuang Han Zhichao Zhang Suping Li Liming Qi Guobao Xu | 2016 | Science China Chemistry2016，59，7： | 5 |
| 5 | First discovery of coesite in eclogite from East Kunlun, northwest China显示文摘Ultrahigh-pressure (UHP)metamorphism plays important roles in continental dynamics.Understanding of this process has been enhanced by the discovery of coesite and micro-diamond from supracrustal rocks [1].Such UHP mineral inclusions provide unequivocal evidence that the least dense part of the lithosphere can be buried to 100-150km or more,and then returned to the surface.Coesite,an ultrahigh-pressure polymorph of SiO2stable above 2.7GPa at metamorphic temperatures,is one of the most important index minerals for UHP metamomhism [1,2]. | Hengzhe Bi Shuguang Song Jinlong Dong Liming Yang Shengsheng Qi Mark B.Allen | 2018 | Science Bulletin2018，63，23： | 4 |
| 6 | Effect of W addition on phase transformation and microstructure of powder metallurgic Ti-22Al-25Nb alloys during quenching and furnace cooling显示文摘Powder metallurgic Ti2 AlNb alloys with W addition are sintered at 900, 1000, 1070 °C,and 1150 °C(i.e., in the O + B2, a_2+ B2 + O, a_2+ B2, and single B2 phase regions, respectively)for 12 h, followed by water quenching and furnace cooling. Comparisons of phase and microstructure between quenched and furnace-cooled W-modified alloys are carried out to illustrate the phase transformation and microstructure evolution during the cooling process. Furthermore, a comparison is also made between W-modified and W-free alloys, to reveal the function of the W alloying.W addition accelerates the solutions of a_2 and O phases during the high-temperature holding, and a Widmannsta¨tten B2 + O structure, which contributes to the properties, is induced by furnace cooling from all the phase regions. The Widmannsta¨tten structure includes a B2 matrix, primary O, and secondary O precipitates. However, W alloying refines the Widmannsta¨tten structure only when the alloys are solution-treated and then cooled from the single B2 phase. Although the hardness of the W-modified alloys is lower than that of the W-free alloys sintered in the same phase region, an enhancement of hardness, 489 ± 18 HV, is obtained in the alloy solution-treated in the single B2 phase region for only 0.5 h. | Junpeng YANG Qi CAI Zongqing MA Yuan HUANG Liming YU Huijun LI Yongchang LIU | 2019 | Chinese Journal of Aeronautics2019，32，5： | 4 |
| 7 | Elastic Scattering of 7Be on Pb Target显示文摘 | Yang Yanyun Wang Jiansong Wang Qi Huang Meirong Ma Junbing Ma Peng Cao Xiguang Han Jianlong Bai Zhen Jin Shilong Hu Qiang Jin Lei Chen Jiangbo Zhang Xueying Chen Ruofu Hu Zhengguo Xu Shiwei Zhen Chuan Xu Zhiguo Xu Hushan Duan Liming Sun Zhiyu Chen Zhiqiang He Jianjun Li Songlin Lei Xiangguo Fu Fen Zhang Xueheng Yuan Xiaohua Du Chengming Yan Xinshuang Hu Jun Tang Shuwen Ye Ruiping Yang Kun Shi Fudong Zhang Wei Chen Ze Li Long Xu Xing Liu Longxiang Zhang Liyong Lin Qingyun Gou Boxing Xu Ge Zhou Xionghong Zhang Yuhu Xiao Guoqing | 2011 | IMP & HIRFL Annual Report2011，，1： | 4 |
| 8 | A post-ingestive amino acid sensor promotes food consumption in Drosophila显示文摘 | Zhe Yang Rui Huang Xin Fu Gaohang Wang Wei Qi Decai Mao Zhaomei Shi Wei L. Shen Liming Wang | 2018 | Cell Research2018，28，10： | 3 |
| 9 | The Main Progress of Perovskite Solar Cells in 2020-2021显示文摘Perovskite solar cells(PSCs)emerging as a promising photovoltaic technology with high efficiency and low manufacturing cost have attracted the attention from all over the world.Both the efficiency and stability of PSCs have increased steadily in recent years,and the research on reducing lead leakage and developing eco-friendly lead-free perovskites pushes forward the commercialization of PSCs step by step.This review summarizes the main progress of PSCs in 2020 and 2021 from the aspects of efficiency,stability,perovskite-based tandem devices,and lead-free PSCs.Moreover,a brief discussion on the development of PSC modules and its challenges toward practical application is provided. | Tianhao Wu Zhenzhen Qin Yanbo Wang Yongzhen Wu Wei Chen Shufang Zhang Molang Cai Songyuan Dai Jing Zhang Jian Liu Zhongmin Zhou Xiao Liu Hiroshi Segawa Hairen Tan Qunwei Tang Junfeng Fang Yaowen Li Liming Ding Zhijun Ning Yabing Qi Yiqiang Zhang Liyuan Han | 2021 | Nano-Micro Letters2021，13，10： | 2 |
| 10 | Retrieval of aerosol size distribution using improved quantum-behaved particle swarm optimization on spectral extinction measurements显示文摘 | Zhenzong He Hong Qi Qin Chen Liming Ruan | 2016 | Particuology2016，14，5： | 2 |
| 11 | Prediction of the coupled heat radiation and conduction parameters and boundary condition using the unscented Kalman filter显示文摘The boundary emissivity, thermal conductivity, and boundary time-varying heat flux in the participating media are retrieved in this work. In the forward model, the coupled radiation-conduction heat transfer in the participating medium is resolved by the finite volume method combined with discrete ordinates method. The inverse model utilizes the temperature signals at the appropriate position of the medium as the known information and uses the unscented Kalman filter(UKF) as an optimization tool to reconstruct the boundary emissivity, thermal conductivity, and boundary time-varying heat flux. It is found that when the emissivity, thermal conductivity, and boundary time-varying heat flux are reconstructed simultaneously, only the temperature information of two locations is required. The influence of the measurement noise, sampling interval, absorption coefficient,process noise covariance, measurement noise covariance on the accuracy and stability of the retrieval results is investigated in detail. All the reconstruction results indicate that the UKF technique is effective and robust for estimating the photothermal parameters and boundary condition of the radiation-conduction heat transfer problems. | WEN Shuang QI Hong WANG YiFei REN YaTao WEI LinYang RUAN LiMing | 2020 | Science China(Technological Sciences)2020，63，3： | 2 |
| 12 | An effective inversion algorithm for retrieving bimodal aerosol particle size distribution from spectral extinction data显示文摘 | Zhenzong He Hong Qi Yuchen Yao Liming Ruan | 2014 | Journal of Quantitative Spectroscopy and Radiative Transfer2014，，： | 2 |
| 13 | Comparison of gut microbiota in autism spectrum disorders and neurotypical boys in China:A case-control study显示文摘Background:Autism spectrum disorders(ASDs)are a set of complex neurobiological disorders.Growing evidence has shown that the microbiota that resides in the gut can modulate brain development via the gut–brain axis.However,direct clinical evidence of the role of the microbiota–gut–brain axis in ASD is relatively limited.Methods:A case-control study of 71 boys with ASD and 18 neurotypical controls was conducted at China-Japan Friendship Hospital.Demographic information and fecal samples were collected,and the gut microbiome was evaluated and compared by 16S ribosomal RNA gene sequencing and metagenomic sequencing.Results:A higher abundance of operational taxonomic units(OTUs)based on fecal bacterial profiling was observed in the ASD group.Significantly different microbiome profiles were observed between the two groups.At the genus level,we observed a decrease in the relative abundance of Escherichia,Shigella,Veillonella,Akkermansia,Provindencia,Dialister,Bifidobacterium,Streptococcus,Ruminococcaceae UCG_002,Megasphaera,Eubacterium_coprostanol,Citrobacter,Ruminiclostridium_5,and Ruminiclostridium_6 in the ASD cohort,while Eisenbergiella,Klebsiella,Faecalibacterium,and Blautia were significantly increased.Ten bacterial strains were selected for clinical discrimination between those with ASD and the neurotypical controls.The highest AUC value of the model was 0.947.Conclusion:Significant differences were observed in the composition of the gut microbiome between boys with ASD and neurotypical controls.These findings contribute to the knowledge of the alteration of the gut microbiome in ASD patients,which opens the possibility for early identification of this disease. | Fang Ye Xinying Gao Zhiyi Wang Shuman Cao Guangcai Liang Danni He Zhitang Lv Liming Wang Pengfei Xu Qi Zhang | 2021 | Synthetic and Systems Biotechnology2021，6，2： | 2 |
| 14 | Dynamic Simulation of Pelagic Longline Retrieval显示文摘To improve fishing gear efficiency, it is important to understand the interactions among sea current, fishing vessel, line hauler, and catches during pelagic longline gear retrieval. In this study, fishing gear configuration parameters, operational parameters, and 3 D ocean current data were collected from Indian Ocean. Dynamic models of pelagic longline gear retrieval were built using the lumped mass method and solved using the Euler-Trapezoidal method. From the results, the pulling force of line hauler exerted on the gear was 2800–3600 N. There were no significant differences(P > 0.05) between the time of the hook retrieval measured at sea and that obtained from the simulation. The absolute values of the movement velocity at representative nodes along the X, Y, and Z axes were 0.01–25.5 m s^(-1). These results suggest that the dynamic model of longline fishing gear retrieval can be used to analyze the interactions among sea current, fishing vessel, line hauler, longline gear, and catches, and to acquire the basic data for optimizing the design of the line hauler. Moreover, the model can serve as a reference to study the hydrodynamic performance of other fishing gears during the hauling process. | SONG Liming QI Yukun LI Jie SHEN Zhibin ZHANG Xinfeng SHEN Xi | 2019 | Journal of Ocean University of China2019，18，2： | 2 |
| 15 | Fusion welding of Fe-added lap joints between AZ31B magnesium alloy and 6061 aluminum alloy by hybrid laser-tungsten inert gas welding technique显示文摘 | Qi Xiaodong Liu Liming | 2012 | Materials and Design2012，33，： | 1 |
| 16 | Strengthening effect of nickel and copper interlayers on hybrid laser-TIG welded joints between magnesium alloy and mild steel显示文摘 | Liming Liu Xiaodong Qi | 2010 | Materials and Design2010，，8： | 1 |
| 17 | Spatio ternporal saliency detection using phase spectrum of qua ternion fourier transform显示文摘 | GUO Chenlei MA Qi ZHANC- Liming | 2008 | CPR2008，，： | 1 |
| 18 | Determination of trace amount of microcystins in water samples using liquid chromatography coupled with triple quadrupole mass spectrometry显示文摘 | Liming Cong Baifen Huang Qi Chen | 2006 | Analytica Chimica Acta2006，569，12： | 1 |
| 19 | Questionnaire on Firefighters’ Protective Clothing in China显示文摘 | Dongmei Huang Hua Yang Zhengkun Qi Lei Xu Xudong Cheng Liming Li Heping Zhang | 2012 | Fire Technology2012，，2： | 1 |
| 20 | Strengthening effect of nickel and copper interlayers on hybrid laser-TIG welded joints between magnesium alloy and mild steel显示文摘 | Liming Liu Xiaodong Qi | 2010 | Materials and Design2010，，8： | 1 |
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