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| 1 | Characterization of particle number size distribution and new particle formation in Southern China显示文摘Knowledge of particle number size distribution(PND) and new particle formation(NPF)events in Southern China is essential for mitigation strategies related to submicron particles and their effects on regional air quality,haze,and human health.In this study,seven field measurement campaigns were conducted from December 2013 to May 2015 using a scanning mobility particle sizer(SMPS) at four sites in Southern China,including three urban sites and one background site.Particles were measured in the size range of15-515 nm,and the median particle number concentrations(PNCs) were found to vary in the range of 0.3× 10~4-2.2 × 10~4 cn^(-3) at the urban sites and were approximately 0.2 × 10~4 cm^(-3) at the background site.The peak diameters at the different sites varied largely from 22 to 102 nm.The PNCs in the Aitken mode(25-100 nm) at the urban sites were up to 10 times higher than they were at the background site,indicating large primary emissions from traffic at the urban sites.The diurnal variations of PNCs were significantly influenced by both rush hour traffic at the urban sites and NPF events.The frequencies of NPF events at the different sites were0%-30%,with the highest frequency occurring at an urban site during autumn.With higher SO_2 concentrations and higher ambient temperatures being necessary,NPF at the urban site was found to be more influenced by atmospheric oxidizing capability,while NPF at the background site was limited by the condensation sink.This study provides a unique dataset of particle number and size information in various environments in Southern China,which can help understand the sources,formation,and the climate forcing of aerosols in this quickly developing region,as well as help constrain and validate NPF modeling. | Xiaofeng Huang Chuan Wang Jianfei Peng Lingyan He Liming Cao Qiao Zhu Jie Cui Zhijun Wu Min Hu | 2017 | Journal of Environmental Sciences2017,29,1: | 4 |
| 2 | Immune escape by SARS-CoV-2 Omicron variant and structural basis of its effective neutralization by a broad neutralizing human antibody VacW-209显示文摘Dear Editor,Coronavirus disease 2019(COVID-19)caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)and its variants is still a pandemic raging across the world(Supplementary information,Fig.S1a,b).A new variant,Omicron,was first detected in South Africa and got dominant in many regions.1 Omicron has been classified as a variant of concern by the World Health Organization(WHO),whose spike carried more than 30 mutations(Supplementary information,Fig.S1c).1,2 To make a comprehensive evaluation of the susceptibility of Omicron,we summarized plasma samples from 19 convalescent individuals infected with the wild-type(WT)virus,and measured their neutralizing activities against the WT,Beta,Delta,Mu,C.1.2,and Omicron(Supplementary information,Figs.S1d and S2).The Omicron showed more serious resistance to neutralizing antibodies(nAbs)than other variants including Beta and Mu(45.6-fold,9.6-fold,and 15.4-fold,respectively,compared with that against the WT)。 | Bin Ju Qingbing Zheng Huimin Guo Qing Fan Tingting Li Shuo Song Hui Sun Senlin Shen Xinrong Zhou Wenhui Xue Lingyan Cui Bing Zhou Shaowei Li Ningshao Xia Zheng Zhang | 2022 | Cell Research2022,32,5: | 1 |
| 3 | Fabrication of the beam splitters for soft X-ray laser application显示文摘The soft X-ray interferometry is completed by the Mach-Zehnder interferometer using a soft X-ray laser, and it is also an important method to measure the electron densities of a laser-produced plasma near the critical surface. It is apparently demonstrated in this paper that the incident angle of each optical element in the soft X-ray Mach- Zehnder interferometer should be near normal incidence based on the polarized characteristics of the soft X-ray mul-tilayers, and the product of reflectivity and transmission of the beam splitter should be taken as a standard of design according to the structure of the soft X-ray Mach-Zehnder interferometer. The beam splitters used in the soft X-ray interferometry at 13.9 nm are fabricated using the ion beam sputtering. The figure error of the beam splitter has reached the nanometer magnitude, in which the product of reflectiv-ity and transmission of the beam splitter is more than 1.6%. | WANG Zhanshan WU Yonggang TANG Weixing QIN Shuji CHEN Lingyan XU Xiangdong HONG Yilin FU Shaojun ZHU Jie CUI Mingqi | 2003 | Chinese Science Bulletin2003,48,18: | 1 |
| 4 | Microstructure and corrosion performance of a cold sprayed aluminium coating on AZ91D magnesium alloy显示文摘 | Yongshan Tao Tianying Xiong Chao Sun Lingyan Kong Xinyu Cui Tiefan Li Guang-Ling Song | 2010 | Corrosion Science2010,,10: | 1 |
| 5 | Oxidation Behavior of TiAl3/Al Composite Coating on Orthorhombic-Ti2AlNb Based Alloy at Different Temperatures显示文摘 | Lingyan Kong Bin Lu Xinyu Cui Hao Du Tiefan Li Tianying Xiong | 2010 | Journal of Thermal Spray Technology2010,,3: | 1 |
| 6 | Construction of a Three-dimensional Covalent Organic Framework via the Linker Exchange Strategy显示文摘Covalent organic framework(COF)is a porous crystalline material with a well-controlled structure and a wide range of potential applications.However,the construction of new COF faces huge challenges,including the design and synthesis of structural unit monomers,the choice of reaction solvent system,and the study of reaction time and temperature.So,it’s particularly important to widen the application scope of synthetic methods and further promote the development of COFs.Here,we performed structural transformations in a three-dimensional(3D)COF(COF-300),and Fourier transform infrared spectroscopy(FTIR),power X-ray diffraction analysis(PXRD)and nitrogen adsorption isotherms confirmed the chemical principles and the successful realization of these exchanges.At the same time,we found that the interpenetrating structure in 3D COF can be changed through the conversion of linkers.The structure simulation successfully proved the transformation of COF from five-fold to seven-fold interpenetration.In addition,in order to prove the versatility of this strategy,we used the same method to convert COF-300 into a high crystallinity 3D COF(TJNU-COF-302)that is also seven-fold interpenetrating and has not been reported.This simple strategy not only makes it easy to obtain a 3D COF connected with imines,which greatly promotes the development of COF,but also provides a new way to develop 3D COFs with complex interpenetrating structures. | CUI Yumeng MIAO Zhuang LIU Qi JIN Fenchun ZHAI Yufeng ZHANG Lingyan WANG Wenli WANG Ke LIU Guiyan ZENG Yongfei | 2022 | Chemical Research in Chinese Universities2022,38,2: | 0 |
| 7 | Effects of Different Enucleation Methods on Developmental Potency of Pig Handmade Clone Reconstructed Embryos显示文摘Effects of different enucleation methods on developmental potency of pig handmade clone(HMC)reconstructed embryo was investigated in the paper.We compared enucleation efficiency of blind cut method,first polar body(Pb1)positioning method and demecolcine(DM)assisted enucleation,as well as their effects on development of HMC reconstructed embryos.The results showed that overall enucleation efficiency of Pb1 positioning method was significantly higher than that of blind cut method(P<0.05).The protuberance rate and overall enucleation efficiency of 0.4μg/mL DM treated group for 60 min was significantly higher than that of other concentrations and time treatment groups(P<0.05).For effects on development of HMC reconstructed embryos,there was no significant difference between DM-assisted enucleation and Pb1 positioning method.In conclusion,appropriate addition of DM could enhance enucleation efficiency of HMC,which had no significant influence on developmental potency of reconstructed embryos. | Lv Lingyan Lu Xingrong Sun Junming Pan Cuiling Lan Haien Wang Yanling Cui Kuiqing Xie Bingkun | 2016 | Animal Husbandry and Feed Science2016,8,3: | 0 |
| 8 | Two antibodies show broad,synergistic neutralization against SARS-CoV-2 variants by inducing conformational change within the RBD显示文摘Continual evolution of the severe acute respiratory syndrome coronavirus(SARS-CoV-2)virus has allowed for its gradual evasion of neutralizing antibodies(nAbs)produced in response to natural infection or vaccination.The rapid nature of these changes has incited a need for the development of superior broad nAbs(bnAbs)and/or the rational design of an antibody cocktail that can protect against the mutated virus strain.Here,we report two angiotensin-converting enzyme 2 competing nAbs—8H12 and 3E2—with synergistic neutralization but evaded by some Omicron subvariants.Cryo-electron microscopy reveals the two nAbs synergistic neutralizing virus through a rigorous pairing permitted by rearrangement of the 472-489 loop in the receptor-binding domain to avoid steric clashing.Bispecific antibodies based on these two nAbs tremendously extend the neutralizing breadth and restore neutralization against recent variants including currently dominant XBB.1.5.Together,these findings expand our understanding of the potential strategies for the neutralization of SARS-CoV-2 variants toward the design of broad-acting antibody therapeutics and vaccines. | Hui Sun Tingting Deng Yali Zhang Yanling Lin Yanan Jiang Yichao Jiang Yang Huang Shuo Song Lingyan Cui Tingting Li Hualong Xiong Miaolin Lan Liqin Liu Yu Li Qianjiao Fang Kunyu Yu Wenling Jiang Lizhi Zhou Yuqiong Que Tianying Zhang Quan Yuan Tong Cheng Zheng Zhang Hai Yu Jun Zhang Wenxin Luo Shaowei Li Qingbing Zheng Ying Gu Ningshao Xia | 2024 | Protein & Cell2024,15,2: | 0 |