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| 1 | Modulation of plasminogen activator inbibitor-1 in vivo: a new mechanism for the anti-fibrotic effect of renin-angiotensin inhibition显示文摘 | OIKAWA T FREEMAN M LO W | 1997 | Kidney Int1997，51，1： | 2 |
| 2 | Cancer Genome Scanning in Plasma: Detection of Tumor-Associated Copy Number Aberrations, Single-Nucleotide Variants, and Tumoral Heterogeneity by Massively Parallel Sequencing显示文摘 | Chan K C Allen Jiang Peiyong Zheng Yama W L Liao Gary J W Sun Hao Wong John Siu Shing Shun N Chan Wing C Chan Stephen L Chan Anthony T C Lai Paul B S Chiu Rossa W K Lo Y M D | 2013 | Clinical Chemistry2013，，1： | 2 |
| 3 | Strategies to tackle the challenges of external beam radiotherapy for liver tumors显示文摘Primary and metastatic liver cancer is an increasingly common and difficult to control disease entity.Radiation offers a non-invasive treatment alternative for these patients who often have few options and a poor prognosis.However,the anatomy and aggressiveness of liver cancer poses significant challenges such as accurate localization at simulation and treatment,management of motion and appropriate selection of dose regimen.This article aims to review the options available and provide information for the practical implementation and/or improvement of liver cancer radiation programs within the context of stereotactic body radiotherapy and image-guided radiotherapy guidelines.Specific patient inclusion and exclusion criteria are presented given the significant toxicity found in certain sub-populations treated with radiation.Indeed,certain sub-populations,such as those with tumor thrombosis or those with larger lesions treated with transarterial chemoembolization,have been shown to have significant improvements in outcome with the addition of radiation and merit special consideration.Implementing a liver radiation programrequires three primary challenges to be addressed:(1) immobilization and motion management;(2) localization;and(3) dose regimen and constraint selection.Strategies to deal with motion include simple internal target volume(ITV) expansions,non-gated ITV reduction strategies,breath hold methods,and surrogate marker methods to enable gating or tracking.Localization of the tumor and organs-at-risk are addressed using contrast infusion techniques to take advantage of different normal liver and cancer vascular anatomy,imaging modalities,and margin management.Finally,a dose response has been demonstrated and dose regimens appear to be converging.A more uniform approach to treatment in terms of technique,dose selection and patient selection will allow us to study liver radiation in larger and,hopefully,multicenter randomized studies. | Michael I Lock Jonathan Klein Hans T Chung Joseph M Herman Edward Y Kim William Small Nina A Mayr Simon S Lo | 2017 | World Journal of Hepatology2017，9，14： | 2 |
| 4 | Rapid clearance of fetal DNA from maternal plasma显示文摘 | Lo Y M Zhang J Leung T N | 1999 | Am J Hum Genet1999，64，： | 1 |
| 5 | Global update on the susceptibility of human influenza viruses to neuraminidase inhibitors, 2012-2013显示文摘 | Meijer A Rebelo-de-Andrade H Correia V Besselaar T Drager-Dayal R Fry A Gregory V Gubareva L Kageyama T Laekenby A Lo J Odagiri T Pere- yaslov D Siqueira M M Takashita E Tashiro M Wang D Wong S Zhang W Daniels R S Hurt A C | 2014 | An- tiviral Research2014，110，： | 1 |
| 6 | A First-Principle Study of Chain Propagation Steps in the Fischer-Tropsch Synthesis on Fe(100)显示文摘 | Lo J M H Ziegler T | 2008 | J Phys Chem C2008，112，13： | 1 |
| 7 | Application of dynamical systems theory to trajectory design for a libration point mission显示文摘 | HOWELL K C BRADEN B T LO M W | 1997 | Journal of Astronautical Sciences1997，45，： | 1 |
| 8 | Nature versus nurture in social insect caste differentiation显示文摘 | SCHWANDER T LO N BEEKMAN M eta | 2010 | Trends in Ecology & Evolution2010，25，5： | 1 |
| 9 | A Modified Probabilistic Data Association Filter in Real Clutter Environmem 显示文摘 | Chen J Leung H LO T Litva J Blanchette M | 1996 | IEEE Transactions on Aerospace and Electronics Systems (S1350- 2395)1996，32，1： | 1 |
| 10 | Adakites from continental collision zones: Melting of thickened lower crust beneath southern Tibet 显示文摘 | Chung S L Liu D Y Ji J Q Chu M F Lee H Y Wen D J Lo C H Lee T Y Qian Q Zhang Q | 2003 | Geology2003，31，11： | 1 |
| 11 | Hydroxylated polymethoxyflavones and methylated flavonoids in sweet orange (Citrus sinensis) peel 显示文摘 | Li S M Lo C Y Ho C T | 2006 | J Agri Food Chem2006，54，12： | 1 |
| 12 | Peritectic coupled growth显示文摘 | Dobler S Lo T S Plapp M | 2004 | Acta Materialia2004，52，： | 1 |
| 13 | On Hilbert spectral represen- tation: A true time -frequency representation for nonlinear and nonstationary data 显示文摘 | Huang N E Chen X Lo M T | 2011 | Advances in Adaptive Data Analysis2011，3，12： | 1 |
| 14 | Portal hyperperfusion injury as the cause of primary nonfunction in a small-for-size liver graft-successful treatment with splenic artery ligation显示文摘 | Lo C M Liu C L Fan S T | 2003 | Liver Transpl2003，9，6： | 1 |
| 15 | Two-phase microstructure selection in peritectic solidification:from island banding to coupled growth显示文摘 | Lo T S Dobler S Plapp M | 2003 | Acta Materialia2003，51，3： | 1 |
| 16 | External drainage of pancreatic duct with a stent to reduce leakage rate of pancreaticojejunostomy after pancreatico-duodenectomy:A prospective randomized trial显示文摘 | Poon R T P Fan S T Lo C M | 2007 | Ann Surg2007，246，3： | 1 |
| 17 | Phase-field modeling of microstructural pattern formation during directional solidification of peritectic alloys without morphological instability显示文摘 | Shing Lo T Karma A Plapp M | 2001 | Phys Rev E2001，63，03： | 1 |
| 18 | Matrix metalloproteinase 2 gene knockout tins no effect on acute brain injury after focal ischemia显示文摘 | Asahi M Sumii T Fini ME Itohara S Lo EH | 2001 | Neuroreport2001，12，13： | 1 |
| 19 | Rapid clearance of fetal DNA from maternal plasma显示文摘 | Lo Y M Zhang J Leung T N | 1999 | Am J Hum Genet1999，64，1： | 1 |
| 20 | Role of nitric oxide in skin flap delay显示文摘 | LO T P Jr THURMOND M | 2004 | Plast Reconstr Surg2004，113，3： | 1 |
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