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| 1 | Paleosalinity in the Tianluoshan site and the correlation between the Hemudu culture and its environmental background显示文摘Tianluoshan 地点的 Paleosalinity 记录从泥土矿物质的 measurations 数据被导出,硼,锶,钡,在在 Tianluoshan 地点的三侧面的领域采样以后。相对的海水平变化根据实验室结果被讨论。记录显示 Tianluoshan 地点定位了的区域见证以前高看台的水平至少三次相对的海,在期间并且在 Hemudu 时期以后。基于以前的研究,这篇论文也集中于包括地讨论 Hemudu 文化的几个环境元素,在环境状况之间的相互关系,人的活动和开发。 | LI Minglin MO Duowen MAO Longjiang SUN Guoping ZHOU Kunshu | 2010 | Journal of Geographical Sciences2010，20，3： | 4 |
| 2 | SQUARE attack on block ciphers with low algebraic degree显示文摘By using an algebraic method, the mathematical foundation of SQUARE attack is studied in this paper. We point out that a SQUARE distinguisher exists if and only if the degree of the polynomial function between n-bit input which is active and n-bit output which is balanced is 2 n-2. And the algebraic method can also be used to determine the property of a balanced set after passed through a nonlinear S-box, by which in some cases we can find a SQUARE distinguisher with more rounds. The validity of SQUARE attack and the influence of the choice of S-box are also studied. If the round function of a Feistel cipher has a low algebraic degree, a SQUARE attack cannot recover the right keys in some special cases. However, SQUARE attack on SPN ciphers always holds. The relations among SQUARE attack and some other cryptanalytic method are studied, showing that if a cipher is breakable by SQUARE attack, then it is also breakable by the interpolation attack. | SUN Bing LI RuiLin QU LongJiang LI Chao | 2010 | Science China(Information Sciences)2010，53，10： | 4 |
| 3 | Refined Kernel Principal Component Analysis Based Feature Extraction显示文摘 | LI Junbao YU Longjiang SUN Shenghe | 2011 | Chinese Journal of Electronics2011，20，3： | 4 |
| 4 | Downregulation of ceramide synthase 1 promotes oral cancer through endoplasmic reticulum stress显示文摘C18 ceramide plays an important role in the occurrence and development of oral squamous cell carcinoma.However,the function of ceramide synthase 1,a key enzyme in C18 ceramide synthesis,in oral squamous cell carcinoma is still unclear.The aim of our study was to investigate the relationship between ceramide synthase 1 and oral cancer.In this study,we found that the expression of ceramide synthase 1 was downregulated in oral cancer tissues and cell lines.In a mouse oral squamous cell carcinoma model induced by 4-nitroquinolin-1-oxide,ceramide synthase 1 knockout was associated with the severity of oral malignant transformation.Immunohistochemical studies showed significant upregulation of PCNA,MMP2,MMP9,and BCL2 expression and downregulation of BAX expression in the pathological hyperplastic area.In addition,ceramide synthase 1 knockdown promoted cell proliferation,migration,and invasion in vitro.Overexpression of CERS1 obtained the opposite effect.Ceramide synthase 1 knockdown caused endoplasmic reticulum stress and induced the VEGFA upregulation.Activating transcription factor 4 is responsible for ceramide synthase 1 knockdown caused VEGFA transcriptional upregulation.In addition,mild endoplasmic reticulum stress caused by ceramide synthase 1 knockdown could induce cisplatin resistance.Taken together,our study suggests that ceramide synthase 1 is downregulated in oral cancer and promotes the aggressiveness of oral squamous cell carcinoma and chemotherapeutic drug resistance. | Wen Chen Chenzhou Wu Yafei Chen Yuhao Guo Ling Qiu Zhe Liu Haibin Sun Siyu Chen Zijian An Zhuoyuan Zhang Yi Li Longjiang Li | 2021 | International Journal of Oral Science2021，13，1： | 3 |
| 5 | Evaluation of Arctic Sea-ice Cover and Thickness Simulated by MITgcm显示文摘A regional Arctic Ocean configuration of the Massachusetts Institute of Technology General Circulation Model(MITgcm)is applied to simulate the Arctic sea ice from 1991 to 2012.The simulations are evaluated by comparing them with observations from different sources.The results show that MITgcm can reproduce the interannual and seasonal variability of the sea-ice extent,but underestimates the trend in sea-ice extent,especially in September.The ice concentration and thickness distributions are comparable to those from the observations,with most deviations within the observational uncertainties and less than 0.5 m,respectively.The simulated sea-ice extents are better correlated with observations in September,with a correlation coefficient of 0.95,than in March,with a correlation coefficient of 0.83.However,the distributions of sea-ice concentration are better simulated in March,with higher pattern correlation coefficients(0.98)than in September.When the model underestimates the atmospheric influence on the sea-ice evolution in March,deviations in the sea-ice concentration arise at the ice edges and are higher than those in September.In contrast,when the model underestimates the oceanic boundaries’influence on the September sea-ice evolution,disagreements in the distribution of the sea-ice concentration and its trend are found over most marginal seas in the Arctic Ocean.The uncertainties of the model,whereby it fails to incorporate the atmospheric information in March and oceanic information in September,contribute to varying model errors with the seasons. | Fei ZHENG Yue SUN Qinghua YANG Longjiang MU | 2021 | Advances in Atmospheric Sciences2021，38，1： | 1 |
| 6 | Print-andscan model and the watermarking countermeasure显示文摘 | YU Longjiang NIU Xiamu SUN Shenghe | 2005 | Image and Vision Computing2005，23，： | 1 |
| 7 | When domestication bottleneck meets weed显示文摘DOMESTICATION OF CROPS BY TWO DIFFERENT SCENARIOS Crop domestication is a unique pattern of plant evolution,commonly referred to as the process of generation of cultivated crops from wild specles due to morphological and gen-etic transformation as a result of human intervention and selec-tion.Studies on the relationship between weeds and crops in archaeology,evolutionary biology,and genetics have revolution-ized our understanding of the role of weeds in the agroecosystem and of the intricacy of crop domestication.Weeds,generally be-ing effective competitors of crops,are not the targets of human cultivation;however,like crops,they can adapt to human-made habitats and thereby are under unintentional human selection.The peculiar environment of the agricultural system alows some arable weeds to develop domestication syndrome,Le.,to mimic crop characteristics,such as plant architecture and seed size,to escape being detected and eradicated. | Yanqing Sun Longbiao Guo Qian-Hao Zhu Longjiang Fan | 2022 | Molecular Plant2022，15，9： | 1 |
| 8 | Fully conversing and highly selective oxidation of benzene to phenol based on MOFs-derived CuO@CN photocatalyst显示文摘Developing highly efficient photocatalysts for selective oxidation of benzene to phenol is of great significance. However, it is still challenging to simultaneously achieve high conversion rate and selectivity.Herein, we demonstrate 99.9% of benzene photoconversion and 99.1% of phenol selectivity under the illumination of AM 1.5 for 12 h. For this purpose, an advanced CuO@CN photocatalyst has been fabricated by loading tubular carbon nitride(CN) with CuO nanoparticles thermally polymerized from Cu-based metal-organic frameworks(MOFs). The sluggish photocharge carrier recombination rate and the excellent stability indicate that the as-prepared nanocomposite is an ideal photocatalyst for benzene oxidation application. This work paves a new avenue for designing novel photocatalyst based on MOFs and carbon nitride materials. | Longjiang Sun Dongxu Wang Yuxin Li Baogang Wu Qi Li Cheng Wang Shuao Wang Baojiang Jiang | 2023 | Chinese Chemical Letters2023，34，4： | 1 |
| 9 | Population genomic analysis reveals domestication of cultivated rye from weedy rye显示文摘Rye(Secale cereale)is an important crop with multiple uses and a valuable genetic resource for wheat breeding.However,due to its complex genome and outcrossing nature,the origin of cultivated rye remains elusive.The geneticist N.I.Vavilov proposed that cultivated rye had been domesticated from weedy rye,rather than directly from wild species like other crops.Unraveling the domestication history of rye will extend our understanding of crop evolution and upend our inherent understanding of agricultural weeds.To this end,in this study we generated the 8.5 Tb of whole-genome resequencing data from 116 worldwide accessions of wild,weedy,and cultivated rye,and demonstrated that cultivated rye was domesticated directly from weedy relatives with a similar but enhanced genomic selection by humans.We found that a repertoire of genes that experienced artificial selection is associated with important agronomic traits,including shattering,grain yield,and disease resistance.Furthermore,we identified a composite introgression in cultivated rye from the wild perennial Secale strictum and detected a 2-Mb introgressed fragment containing a candidate ammonium transporter gene with potential effect on the grain yield and plant growth of rye.Taken together,our findings unravel the domestication history of cultivated rye,suggest that interspecific introgression serves as one of the likely causes of obscure species taxonomy of the genus Secale,and provide an important resource for future rye and wheat breeding. | Yanqing Sun Enhui Shen Yiyu Hu Dongya Wu Yu Feng Sangting Lao Chenfeng Dong Tianyu Du Wei Hua Chu-Yu Ye Jinhuan Zhu Qian-Hao Zhu Daguang Cai Lidia Skuza Jie Qiu Longjiang Fan | 2022 | Molecular Plant2022，15，3： | 1 |
| 10 | Print-and-scan model and the watermarking countermeasure显示文摘 | Yu Longjiang Niu Xiamu Sun Shenghe | 2005 | Image and Vision Computing2005，23，9： | 1 |
| 11 | Weedy rice, a hidden gold mine in the paddy field显示文摘Weedy rice(Oryza spp.)is an increasingly invasive paddy weed,which mimics cultivated rice at the seedling stage but is distinguished from cultivated rice with strong seed shattering and seed dormancy,which are typical phenotypic characteristics of wild rice.On the origins of this conspecific form of cultivated rice(Oryza sativa),four hypotheses have been proposed and debated for decades:(1)origination from wild rice(Oryza rufipogon or possibly other wild Oryza species);(2)origination following hybridization between wild and cultivated rice;(3)direct descent from escaped cultivated rice;and(4)intervarietal hybridization between different domesticated rice varieties(Ellstrand et al.,2010).Recent population genomic investigations based on whole-genome variation provide powerful phylogenetic and demographic evidence for the de-domestication origination of weedy rice(Li et al.,2017;Qiu et al.,2017,Qiu et al.,2020;Sun et al.,2019). | Dongya Wu Jie Qiu Jian Sun Beng-Kah Song Kenneth M.Olsen Longjiang Fan | 2022 | Molecular Plant2022，15，4： | 0 |
| 12 | Response of Spring Phenology of Main Gymnosperm to Climate Change in Harbin City Proper显示文摘Global climate change has caused phenology change of vegetation.This is especially obvious in urban area.This paper reveals response mechanism of spring phenology of main gymnosperm in Harbin City proper to climate change based on relationship study between two typical phenophases(beginning of bud burst and beginning of leaf expansion) of Korean pine(Pinus koraiensis),Koyama spruce(Picea koraiensis Nakai),needle fir(Abies nephrolepis) and Pinus sylvestnis var.mongolica Litv.and the temperature of every ten days in winter and spring through the phenology observation in Harbin proper from 1963 to 2008 and meteorological observation data from 1951 to 2008.Study conclusion shows the advancing trend of the beginning date of accumulated temperature that meets plant germination in Harbin City.The beginning of bud burst of P.koraiensis is mainly subject to temperature in middle and late February and the beginning pf leaf expansion is subject to temperature in middle and late March.The beginning of bud burst of P.koraiensis Nakai is mainly subject to temperature from late January to middle of February and leaf expansion is subject to temperature mainly in March and April.The beginning of bud burst of A.nephrolepis is mainly subject to temperature from January to March and leaf expansion time is subject to temperature in May.The beginning of bud burst of P.sylvestnis var.mongolica Litv.is mainly subject to the middle of March and the middle of April.The spring phenology of all these 4 selected species showed tremendous advancement.However the advancing trend of different species is varied.The impact level of temperature in each phase to spring phenology of different species is different.The spring phenology of all 4 selected species is prominently relevant to the temperature in earlier period before occurrence of phenology.Low temperature is a favor for breaking dormancy of plants.Suitable lower temperature is good for advancing spring phenology of plants.Temperature in Harbin is relatively lower in winter.Increase of temperature in winter is propitious to advancing of spring phenology of plants. | PEI Shunxiang 1,3 LI Changhai2 GUO Quanshui3 XIN Xuebing1 SUN Jianxin4 HONG Ming3 1.Experimental Centre of Forestry in North China,Chinese Academy of Forestry,Beijing 102300,R.P.China 2.Forest Botanical Garden,Hei Longjiang Province,Harbin 150040,R.P.China 3.Research Institute of Forest Ecology,Chinese Academy of Forestry,Beijing 100091,R.P.China 4.Beijing Forestry University,Beijing 100083,R.P.China | 2010 | Chinese Forestry Science and Technology2010，9，3： | 0 |
| 13 | Experimental investigation of relationship between homeobox gene and pathogenesis of hemangioma显示文摘 | Wei Dai Longjiang Li Yuanding Huang Gang Sun | 2008 | 中国口腔颌面外科杂志2008，6，B05： | 0 |
| 14 | Expert consensus on the clinical application of recombinant adenovirus human p53 for head and neck cancers显示文摘The first gene therapy product,recombinant adenovirus human p53(rAd-p53),has been approved by CFDA since 2013.During these years,most of the clinical trials and the relevant basic research were carried out by Chinese oncologists.Gendicine was proved to be a safe and promising gene therapy drug for patients who suffered from head and neck squamous cell carcinoma(HNSCC).The basic therapeutic theories of gene therapy were totally different from the traditional ones,such as surgeries or radioand chemotherapy,and the evaluation of treatment outcomes should also be changed simultaneously.However,there still existed a lot of misunderstandings about gene therapy,which resulted in improper administration,insufficient dosage calculation,and treatment cycles,and the treatment outcomes were unsatisfactory,especially for inexperienced oncologists or hospitals.Therefore,we will provide some practical guidance here on the gene therapy of rAd-p53 based on our previous research and experience,which focused on the basic theories and clinical issues,to answer the questions arising during the clinical of gene therapy and to accelerate the development of gene therapy for the benefit of patients bearing malignant tumors. | Yi Li Wei Guo Xiuqin Li Jianguo Zhang Moyi Sun Zhangui Tang Wei Ran Kai Yang Guilin Huang Longjiang Li | 2021 | International Journal of Oral Science2021，13，4： | 0 |
| 15 | Study design of deep learning based automatic detection of cerebrovascular diseases on medical imaging: a position paper from Chinese Association of Radiologists显示文摘In recent years,with the development of artificial intelligence,especially deep learning technology,researches on automatic detection of cerebrovascular diseases on medical images have made tremendous progress and these models are gradually entering into clinical practice.However,because of the complexity and flexibility of the deep learning algorithms,these researches have great variability on model building,validation process,performance description and results interpretation.The lack of a reliable,consistent,standardized design protocol has,to a certain extent,affected the progress of clinical translation and technology development of computer aided detection systems.After reviewing a large number of literatures and extensive discussion with domestic experts,this position paper put forward recommendations of standardized design on the key steps of deep learning-based automatic image detection models for cerebrovascular diseases.With further research and application expansion,this position paper would continue to be updated and gradually extended to evaluate the generalizability and clinical application efficacy of such tools. | Longjiang Zhang Zhao Shi Min Chen Yingmin Chen Jingliang Cheng Li Fan Nan Hong Wenxiao Jia Guihua Jiang Shenghong Ju Xiaogang Li Xiuli Li Changhong Liang Weihua Liao Shiyuan Liu Zaiming Lu Lin Ma Ke Ren Pengfei Rong Bin Song Gang Sun Rongpin Wang Zhibo Wen Haibo Xu Kai Xu Fuhua Yan Yizhou Yu Yunfei Zha Fandong Zhang Minwen Zheng Zhen Zhou Wenzhen Zhu Guangming Lu Zhengyu Jin on behalf of Chinese Association of Radiologists | 2022 | Intelligent Medicine2022，2，4： | 0 |
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