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45篇 您的检索式:作者名="Lutzke"
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1Assessment of the diagnostic performance and interobserver variability of endocytoscopy in Barrett's esophagus:A pilot ex-vivo study显示文摘AIM:To investigate a classification of endocytoscopy(ECS)images in Barrett’s esophagus(BE)and evaluate its diagnostic performance and interobserver variability.METHODS:ECS was applied to surveillance endoscopic mucosal resection(EMR)specimens of BE ex-vivo.The mucosal surface of specimen was stained with 1%methylene blue and surveyed with a catheter-type endocytoscope.We selected still images that were most representative of the endoscopically suspect lesion and matched with the final histopathological diagnosis to accomplish accurate correlation.The diagnostic performance and inter-observer variability of the new classification scheme were assessed in a blinded fashion by physicians with expertise in both BE and ECS and inexperienced physicians with no prior exposure to ECS.RESULTS:Three staff physicians and 22 gastroenterology fellows classified eight randomly assigned unknown still ECS pictures(two images per each classification)into one of four histopathologic categories as follows:(1)BEC1-squamous epithelium;(2)BEC2-BE without dysplasia;(3)BEC3-BE with dysplasia;and(4)BEC4-esophageal adenocarcinoma(EAC)in BE.Accuracy of diagnosis in staff physicians and clinical fellows were,respectively,100%and 99.4%for BEC1,95.8%and83.0%for BEC2,91.7%and 83.0%for BEC3,and95.8%and 98.3%for BEC4.Interobserver agreement of the faculty physicians and fellows in classifying each category were 0.932 and 0.897,respectively.CONCLUSION:This is the first study to investigate classification system of ECS in BE.This ex-vivo pilot study demonstrated acceptable diagnostic accuracy and excellent interobserver agreement.Yutaka Tomizawa Prasad G Iyer Louis M Wongkeesong Navtej S Buttar Lori S Lutzke Tsung-Teh Wu Kenneth K Wang 2013World Journal of Gastroenterology2013,19,46:2
2Utility of Biomarkers in Prediction of Response to Ablative Therapy in Barrett’s Esophagus显示文摘Ganapathy A. Prasad Kenneth K. Wang Kevin C. Halling Navtej S. Buttar Louis–Michel Wongkeesong Alan R. Zinsmeister Shannon M. Brankley Emily G. Barr Fritcher Wytske M. Westra Kausilia K. Krishnadath Lori S. Lutzke Lynn S. Borkenhagen 2008Gastroenterology2008,,:2
3Endoscopic and Surgical Treatment of Mucosal (T1a) Esophageal Adenocarcinoma in Barrett’s Esophagus显示文摘Ganapathy A. Prasad Tsung Teh Wu Dennis A. Wigle Navtej S. Buttar Louis–Michel Wongkeesong Kelly T. Dunagan Lori S. Lutzke Lynn S. Borkenhagen Kenneth K. Wang 2009Gastroenterology2009,,:2
4Kinetics of murine gammaherpesvirus 68 gene expression following infection of murine cells in culture and in mice 显示文摘Rochford R Lutzke M L Alfinito R S 2001J Virol2001,75,11:1
5Outcomes of T1 b esophageal adenocarcinoma patients 显示文摘Tian J Prasad GA Lutzke LS 2011Gastrointest Endosc2011,74,6:1
6Nitric Oxide-releasing S-Nitrosated Deriva- tives of Chitin and Chitosan for Biomedical Applica- tions显示文摘LUTZKE A PEGALAJAR-JURADO A NEUFELD B H 2014J Mater Chem B2014,,2:1
7Outcomes of Tlb esophageal adenocareinoma patients 显示文摘Tian J Prasad GA Lutzke LS 2011Gastrointest Endosc2011,74,6:1
8Diagnostic performance of two confocal endomicroscopy systems in detecting Barrett’s dysplasia: a pilot study using a novel bioprobe in ex vivo tissue显示文摘Emmanuel C. Gorospe Cadman L. Leggett Gang Sun Marlys A. Anderson Milli Gupta Joshua D. Penfield Lori Lutzke Jason T. Lewis Louis M. Wong Kee Song Kenneth K. Wang 2012Gastrointestinal Endoscopy2012,,5:1
9Overutilization of endoscopic surveillance in nondysplastic Barrett’s esophagus: a multicenter study显示文摘Seth D. Crockett Isaac M. Lipkus Stephanie D. Bright Richard E. Sampliner Kenneth K. Wang Vikram Boolchand Lori S. Lutzke Nicholas J. Shaheen 2012Gastrointestinal Endoscopy2012,,1:1
10Endoscopic and Surgical Treatment of Mucosal (T1a) Esophageal Adenocarcinoma in Barrett’s Esophagus显示文摘Ganapathy A. Prasad Tsung Teh Wu Dennis A. Wigle Navtej S. Buttar Louis–Michel Wongkeesong Kelly T. Dunagan Lori S. Lutzke Lynn S. Borkenhagen Kenneth K. Wang 2009Gastroenterology2009,,3:1
11Prediction of response to endoscopic therapy of Barrett’s dysplasia by using genetic biomarkers显示文摘Margriet R. Timmer Shannon M. Brankley Emmanuel C. Gorospe Gang Sun Lori S. Lutzke Prasad G. Iyer Kevin C. Halling Kausilia K. Krishnadath Kenneth K. Wang 2014Gastrointestinal Endoscopy2014,,:1
12Positive correlation between endoscopist radiofrequency ablation volume and response rates in Barrett’s esophagus显示文摘David I. Fudman Charles J. Lightdale John M. Poneros Gregory G. Ginsberg Gary W. Falk Maureen Demarshall Milli Gupta Prasad G. Iyer Lori Lutzke Kenneth K. Wang Julian A. Abrams 2014Gastrointestinal Endoscopy2014,,:1
13Identification of a hexapeptide inhibitor of the human immunodeficiency virus integrase protein by using a combinatorial chemical library 显示文摘Puras Lutzke RA Eppens NA Weber PA 1995Proceedings of the Natii3alAcademy of Sciences of the United Sstates of America1995,92,11:1
14The role of cellular senescence in the gastrointestinal mucosa 显示文摘Penfield JD Anderson M Lutzke L 2013Gut Liver2013,7,3:1
15Recurrence of Esophageal Intestinal Metaplasia After Endoscopic Mucosal Resection and Radiofrequency Ablation of Barrett’s Esophagus: Results From a US Multicenter Consortium显示文摘Milli Gupta Prasad G. Iyer Lori Lutzke Emmanuel C. Gorospe Julian A. Abrams Gary W. Falk Gregory G. Ginsberg Anil K. Rustgi Charles J. Lightdale Timothy C. Wang David I. Fudman John M. Poneros Kenneth K. Wang 2013Gastroenterology2013,,1:1
16Extent of high-grade dysplasia in Barrett’s esophagus correlates with risk of adenocarcinoma显示文摘Navtej S. Buttar Kenneth K. Wang Thomas J. Sebo Darren M. Riehle Krishnawatie K. Krishnadath Lori S. Lutzke Marlys A. Anderson Tanya M. Petterson Lawrence J. Burgart 2001Gastroenterology2001,,7:1
17The DNA binding domain of HIV-1 integrase has all SH3-like fold显示文摘Eijkelenboom A P Lutzke R A Bcelens R 1995Nat Struct Biol1995,2,:1
18Photodynamic therapy for Barrett's esophagus:does light still have a role?显示文摘WANG K K LUTZKE L BORKENHAGEN L 2008Endoscopy2008,40,6:1
19Structure-based mutational analysis of the C-terminal DNA-binding domain of human immunodeficiency virus type 1 integrase:Critical residues for protein oligomcrization and DNA binding显示文摘Lutzke R A Plasterk R H 1998J Virol1998,72,:1
20Combined endoscopic mucosal resection and photodynamic therapy for esophageal neoplasia within Barrett's esophagus显示文摘Buttar NS Wang KK Lutzke LS et al 2001Gastrointest Endoac2001,54,6:1
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