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| 1 | Role of microbial dysbiosis in the pathogenesis of esophageal mucosal disease:A paradigm shift from acid to bacteria?显示文摘Genomic sequencing,bioinformatics,and initial speciation(e.g.,relative abundance)of the commensal microbiome have revolutionized the way we think about the“human”body in health and disease.The interactions between the gut bacteria and the immune system of the host play a key role in the pathogenesis of gastrointestinal diseases,including those impacting the esophagus.Although relatively stable,there are a number of factors that may disrupt the delicate balance between the luminal esophageal microbiome(EM)and the host.These changes are thought to be a product of age,diet,antibiotic and other medication use,oral hygiene,smoking,and/or expression of antibiotic products(bacteriocins)by other flora.These effects may lead to persistent dysbiosis which in turn increases the risk of local inflammation,systemic inflammation,and ultimately disease progression.Research has suggested that the etiology of gastroesophageal reflux disease-related esophagitis includes a cytokine-mediated inflammatory component and is,therefore,not merely the result of esophageal mucosal exposure to corrosives(i.e.,acid).Emerging evidence also suggests that the EM plays a major role in the pathogenesis of disease by inciting an immunogenic response which ultimately propagates the inflammatory cascade.Here,we discuss the potential role for manipulating the EM as a therapeutic option for treating the root cause of various esophageal disease rather than just providing symptomatic relief(i.e.,acid suppression). | Steve M D'Souza Kevin Houston Lauren Keenan Byung Soo Yoo Parth J Parekh David A Johnson | 2021 | World Journal of Gastroenterology2021，27，18： | 8 |
| 2 | Optical burst switching(OBS): a new paradigm for an optical internet显示文摘 | Qiao C Yoo M | 1999 | J High Speed Networks1999，8，1： | 2 |
| 3 | Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression显示文摘 | Yoo Byoung Kwon Emdad Luni Su Zao-zhong Villanueva Augusto Chiang Derek Y Mukhopadhyay Nitai D Mills Alan Scott Waxman Samuel Fisher Robert A Llovet Josep M Fisher Paul B Sarkar Devanand | 2009 | Journal of Clinical Investigation2009，，3： | 2 |
| 4 | Preparation of mesostructured barium sulfate with high surface area by dispersion method and its characterization显示文摘 | NAGARAJA B M ABIMANYU H JUNG K D YOO K S | 2007 | J Colloid Interf Sci2007，316，： | 1 |
| 5 | Inactivation of DFR (Dihydroflavonol 4-reductase) gene transcription results in blockage of anthocyanin production in yellow onions (Allium cepa)显示文摘 | KIM S G BINZEL M L PARK S H YOO K S PIKE L M | 2004 | Molecular Breeding2004，14，： | 1 |
| 6 | The Impact of Marketing - induced Versus Word - of - mouth Customer Acquisition on Customer Equity Growth 显示文摘 | Villanueva J Yoo S Hanssens D M | 2008 | Journal of Marketing Research2008，45，1： | 1 |
| 7 | Design and operation consid-erations for wastewater treatment of municipal wastewater显示文摘 | Shim J K Yoo I K Lee Y M | 2002 | Water Research2002，36，： | 1 |
| 8 | A high speed protocol for bursty traffic in optical networks 显示文摘 | YOO M JEONG M QIAO C | 1997 | SPIE1997，3230，： | 1 |
| 9 | Optical burst switching(OBS)-a new paradigm for an optical Internet显示文摘 | Qiao C Yoo M | 1999 | Joumal of High Speed Networks1999，18，1： | 1 |
| 10 | Optical burst switching for service differentiation in the next-generation optical internet 显示文摘 | M Yoo C Qiao S Dixit | 2001 | IEEE Communications Magazine2001，39，2： | 1 |
| 11 | Optical burst switching (obs)-a new paradigm for an optical internet显示文摘 | QIAO C M YOO M | 1999 | Journal o j High SpeedNetworks1999，8，1： | 1 |
| 12 | A cost - efficient WDM - PON architecture supporting dynamic wavelength and time slot allocation显示文摘 | Kim H Hwang J Yoo M | 2007 | ICACT2007，，3： | 1 |
| 13 | Effects of salts and preheating temperature of brine on the texture of pickled cucumbers显示文摘 | Yoo K M Hwang I K Moon B | 2006 | Food Chemistry and Toxicology2006，71，2： | 1 |
| 14 | Greater and lesser omenta: normal anatomy and pathologic processes 显示文摘 | Yoo E Kim J H Kim M J | 2007 | Radiographics2007，27，3： | 1 |
| 15 | Comparison of immunomodulatory properties of mesenchymal stem cells derived from adult human tissues显示文摘 | YOO K H JANG I K LEE M W | | 0，，02： | 1 |
| 16 | Electropolymerization mechanism for poly (o-phenylenediamine) (ppd) and its electrocatalytic behavior for O2 reduction显示文摘 | Jang D H Yoo Y S Oh S M | | 0，，05： | 1 |
| 17 | Phylogeny and diversificatoin of B-function MADS-box genes in angiosperms: Evolutionary and functional implications of a 260-million-year-old duplication显示文摘 | Kim S Yoo M J Albert V A | 2004 | Am J Bot2004，91，： | 1 |
| 18 | Early os- teogenic differentiation of mouse preosteoblasts induced by collagen-derived DGEA-peptide on nanofibrous phage tissue matrices 显示文摘 | Yoo S Y Kobayashi M Lee P P Lee S W | 2011 | Biomacromolecules2011，12，4： | 1 |
| 19 | Doppler shift spectroscopy for the measurement of angular divergence and ion species of ion beam 显示文摘 | Yoo S J YANG H L HWANG S M | 1999 | Journal of the Korean Physics Society1999，35，： | 1 |
| 20 | Nonbasal deformation modes of HCP metals and alloys: Role of dislocation source and mobility显示文摘 | Yoo M H Morris J R Ho K M | 2002 | Metall Mater Trans2002，33，： | 1 |
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