|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Anisotropic coding metamaterials and their powerful manipulation of differently polarized terahertz waves显示文摘Metamaterials based on effective media can be used to produce a number of unusual physical properties(for example,negative refraction and invisibility cloaking)because they can be tailored with effective medium parameters that do not occur in nature.Recently,the use of coding metamaterials has been suggested for the control of electromagnetic waves through the design of coding sequences using digital elements‘0’and‘1,'which possess opposite phase responses.Here we propose the concept of an anisotropic coding metamaterial in which the coding behaviors in different directions are dependent on the polarization status of the electromagnetic waves.We experimentally demonstrate an ultrathin and flexible polarization-controlled anisotropic coding metasurface that functions in the terahertz regime using specially designed coding elements.By encoding the elements with elaborately designed coding sequences(both 1-bit and 2-bit sequences),the x-and y-polarized waves can be anomalously reflected or independently diffused in three dimensions.The simulated far-field scattering patterns and near-field distributions are presented to illustrate the dual-functional performance of the encoded metasurface,and the results are consistent with the measured results.We further demonstrate the ability of the anisotropic coding metasurfaces to generate a beam splitter and realize simultaneous anomalous reflections and polarization conversions,thus providing powerful control of differently polarized electromagnetic waves.The proposed method enables versatile beam behaviors under orthogonal polarizations using a single metasurface and has the potential for use in the development of interesting terahertz devices. | Shuo Liu Tie Jun Cui Quan Xu Di Bao Liangliang Du Xiang Wan Wen Xuan Tang Chunmei Ouyang Xiao Yang Zhou Hao Yuan Hui Feng Ma Wei Xiang Jiang Jiaguang Han Weili Zhang Qiang Cheng | 2016 | Light(Science & Applications)2016，5，1： | 36 |
| 2 | Smart metasurface with self-adaptively reprogrammable functions显示文摘Intelligence at either the material or metamaterial level is a goal that researchers have been pursuing.From passive to active,metasurfaces have been developed to be programmable to dynamically and arbitrarily manipulate electromagnetic(EM)wavefields.However,the programmable metasurfaces require manual control to switch among different functionalities.Here,we put forth a smart metasurface that has self-adaptively reprogrammable functionalities without human participation.The smart metasurface is capable of sensing ambient environments by integrating an additional sensor(s)and can adaptively adjust its EM operational functionality through an unmanned sensing feedback system.As an illustrative example,we experimentally develop a motion-sensitive smart metasurface integrated with a three-axis gyroscope,which can adjust self-adaptively the EM radiation beams via different rotations of the metasurface.We develop an online feedback algorithm as the control software to make the smart metasurface achieve single-beam and multibeam steering and other dynamic reactions adaptively.The proposed metasurface is extendable to other physical sensors to detect the humidity,temperature,illuminating light,and so on.Our strategy will open up a new avenue for future unmanned devices that are consistent with the ambient environment. | Qian Ma Guo Dong Bai Hong Bo Jing Cheng Yang Lianlin Li Tie Jun Cui | 2019 | Light(Science & Applications)2019，8，1： | 13 |
| 3 | Mechanical Harvesting Effects on Seed Yield Loss,Quality Traits and Profitability of Winter Oilseed Rape (Brassica napus L.)显示文摘China is one of the most important rapeseed producing countries in the world. Effective mechanical harvesting time for decreasing harvesting loss of winter oilseed rape has been becoming a critical factor. An elite cultivar Zhongshuang 11 (Brassica napus L.) was employed in two rounds of field experiments from 2009 to 2011. Seeds were sown with machine, three combine harvesting times namely combine harvesting A, B, and C (CHA, CHB, and CHC) were designed and manual harvesting (MH) as control was performed at maturity. The harvesting treatments were determined according to color of pod and seed in the field. Seed yield loss and quality in different treatments were evaluated. Results showed that both seed yields and harvesting losses in 2009-2010 were higher than that in 2010-2011, whereas seed oil contents in 2010-2011 were higher than that in 2009-2010. The highest yield appeared in CHB, which was significantly higher than that in MH. Furthermore, harvesting loss in CHB were 50% that in MH. Seed oil content and chlorophyll exhibited no obvious difference between CHB and MH. Economic profit analysis demonstrated that mechanical sowing/combine harvesting (MS/CH) showed an input/output ratio of 1:1.6, and it was 1:1.2 in mechanical sowing/manual harvesting (MS/MH). Labor-cost accounted for more than 70% of the total cost in MS/MH, which led to low profitability to a great extent. Our results suggested that CHB was the optimum harvesting time for winter oilseed rape along the Yangtze River. | MA Ni ZHANG Chun-lei LI Jun ZHANG Ming-hai CHENG Yu-gui LI Guang-ming ZHANG Shu-jie | 2012 | Journal of Integrative Agriculture2012，11，8： | 13 |
| 4 | Measurement of residual stress in a multi-layer semiconductor heterostructure by micro-Raman spectroscopy显示文摘Si-based multilayer structures are widely used in current microelectronics. During their preparation, some inhomogeneous residual stress is induced, resulting in competition between interface mismatching and surface energy and even leading to structure failure. This work presents a methodological study on the measurement of residual stress in a multi-layer semiconductor heterostructure. Scanning electron microscopy(SEM), micro-Raman spectroscopy(MRS), and transmission electron microscopy(TEM) were applied to measure the geometric parameters of the multilayer structure. The relationship between the Raman spectrum and the stress/strain on the [100] and [110] crystal orientations was determined to enable surface and crosssection residual stress analyses, respectively. Based on the Raman mapping results, the distribution of residual stress along the depth of the multi-layer heterostructure was successfully obtained. | Wei Qiu Cui-Li Cheng Ren-Rong Liang Chun-Wang Zhao Zhen-Kun Lei Yu-Cheng Zhao Lu-Lu Ma Jun Xu Hua-Jun Fang Yi-Lan Kang | 2016 | Acta Mechanica Sinica2016，32，5： | 12 |
| 5 | Hesperetin derivative-12 (HDND-12) regulates macrophage polarization by modulating JAK2/STAT3 signaling pathway显示文摘Macrophages show significant heterogeneity in function and phenotype, which could shift into different populations of cells in response to exposure to various micro-environmental signals. These changes, also termed as macrophage polarization, of which play an important role in the pathogenesis of many diseases. Numerous studies have proved that Hesperidin(HDN), a traditional Chinese medicine, extracted from fruit peels of the genus citrus, play key roles in anti-inflammation, anti-tumor, anti-oxidant and so on. However, the role of HDN in macrophage polarization has never been reported. Additional, because of its poor water solubility and bioavailability. Our laboratory had synthesized many hesperidin derivatives. Among them, hesperidin derivatives-12(HDND-12) has better water solubility and bioavailability. So, we evaluated the role of HDND-12 in macrophage polarization in the present study. The results showed that the expression of Arginase-1(Arg-1), interleukin-10(IL-10), transforming growth factor β(TGF-β) were up-regulated by HDND-12, whereas the expression of inducible Nitric Oxide Synthase(iNOS) was down-regulated in LPS-and IFN-γ-treated(M1) RAW264.7 cells. Moreover, the expression of p-JAK2 and p-STAT3 were significantly decreased after stimulation with HDND-12 in M1-like macrophages. More importantly, when we taken AG490(inhibitor of JAK2/STAT3 signaling), the protein levels of iNOS were significantly reduced in AG490 stimulation group compare with control in LPS, IFN-γ and HDND-12 stimulation cells. Taken together, these findings indicated that HDND-12 could prevent polarization toward M1-like macrophages, at least in part, through modulating JAK2/STAT3 pathway. | KONG Ling-Na LIN Xiang HUANG Cheng MA Tao-Tao MENG Xiao-Ming HU Chao-Jie WANG Qian-Qian LIU Yan-Hui SHI Qing-Ping LI Jun | 2019 | Chinese Journal of Natural Medicines2019，17，2： | 12 |
| 6 | Efficient revocation in ciphertext-policy attribute-based encryption based cryptographic cloud storage显示文摘It is secure for customers to store and share their sensitive data in the cryptographic cloud storage.However,the revocation operation is a sure performance killer in the cryptographic access control system.To optimize the revocation procedure,we present a new efficient revocation scheme which is efficient,secure,and unassisted.In this scheme,the original data are first divided into a number of slices,and then published to the cloud storage.When a revocation occurs,the data owner needs only to retrieve one slice,and re-encrypt and re-publish it.Thus,the revocation process is accelerated by affecting only one slice instead of the whole data.We have applied the efficient revocation scheme to the ciphertext-policy attribute-based encryption(CP-ABE) based cryptographic cloud storage.The security analysis shows that our scheme is computationally secure.The theoretically evaluated and experimentally measured performance results show that the efficient revocation scheme can reduce the data owner's workload if the revocation occurs frequently. | Yong CHENG Zhi-ying WANG Jun MA Jiang-jiang WU Song-zhu MEI Jiang-chun REN | 2013 | Journal of Zhejiang University-Science C(Computers and Electronics)2013，14，2： | 11 |
| 7 | High quality reference genome of drumstick tree(Moringa oleifera Lam.), a potential perennial crop显示文摘The drumstick tree(Moringa oleifera Lam.) is a perennial crop that has gained popularity in certain developing countries for its high-nutrition content and adaptability to arid and semi-arid environments. Here we report a high-quality draft genome sequence of M. oleifera. This assembly represents 91.78% of the estimated genome size and contains 19,465 protein-coding genes. Comparative genomic analysis between M. oleifera and related woody plant genomes helps clarify the general evolution of this species, while the identification of several species-specific gene families and positively selected genes in M. oleifera may help identify genes related to M. oleifera's high protein content, fast-growth, heat and stress tolerance. This reference genome greatly extends the basic research on M. oleifera, and may further promote applying genomics to enhanced breeding and improvement of M. oleifera. | TIAN Yang ZENG Yan ZHANG Jing YANG Cheng Guang YAN Liang WANG XuanJun SHI ChongYing XIE Jing DAI TianYi PENG Lei ZENG HUAN Yu XU An Ni HUANG YeWei ZHANG JiaJin MA Xiao DONG Yang HAO ShuMei SHENG Jun | 2015 | Science China(Life Sciences)2015，58，7： | 10 |
| 8 | Designation and development of biomedical Ti alloys with finer biomechanical compatibility in long-term surgical implants显示文摘与优秀 biomechanical 相容性开发新钛合金是一个重要研究方向外科植入材料。现在的纸总结生物医学的钛合金的国际研究和开发。瞄准增加 biomechanical 相容性,它也介绍合金设计的探索和改进,机械处理,微观结构和阶段转变,并且以后最后为关于生物医学的钛合金的科学研究构画出方向。 | Zhen-Tao YU Ming-Hua ZHANG Yu-Xing TIAN Jun CHENG Xi-Qun MA Han-Yuan LIU Chang WANG | 2014 | Frontiers of Materials Science2014，8，3： | 9 |
| 9 | Effect of betulinic acid on the regulation of Hiwi and cyclin B1 in human gastric adenocarcinoma AGS cells显示文摘 | Li-jing YANG Yan CHEN Qi MA Jun FANG Jing HE Yi-quan CHENG Qiu-ling WU | 2010 | Acta Pharmacologica Sinica2010，31，1： | 9 |
| 10 | Prognostic values of the integrated model incorporating the volume of metastatic regional cervical lymph node and pretreatment serum Epstein-Barr virus DNA copy number in predicting distant metastasis in patients with N1 nasopharyngeal carcinoma显示文摘Background: According to the 7 th edition of the American Joint Committee on Cancer(AJCC) staging system, over50% of patients with nasopharyngeal carcinoma(NPC) have N1 disease at initial diagnosis. However, patients with N1 NPC are relatively under-researched, and the metastasis risk of this group is not well-stratified. This study aimed to evaluate the prognostic values of gross tumor volume of metastatic regional lymph node(GTVnd) and pretreatment serum copy number of Epstein-Barr virus(EBV) DNA in predicting distant metastasis of patients with N1 NPC, and to develop an integrated prognostic model that incorporates GTVnd and EBV DNA copy number for this group of patients.Methods: The medical records of 787 newly diagnosed patients with nonmetastatic, histologically proven N1 NPC who were treated at Sun Yat-sen University Cancer Center between November 2009 and February 2012 were analyzed. Computed tomography-derived GTVnd was measured using the summation-of-area technique. Blood samples were collected before treatment to quantify plasma EBV DNA. The receiver operating characteristic(ROC) curve analysis was used to evaluate the cut-off point for GTVnd, and the area under the ROC curve was used to assess the predicted validity of GTVnd. The survival rates were assessed by Kaplan-Meier analysis, and the survival curves were compared using a log-rank test. Multivariate analysis was conducted using the Cox proportional hazard regression model.Results: The 5-year distant metastasis-free survival(DMFS) rates for patients with GTVnd > 18.9 vs.≤ 18.9 mL were82.2% vs. 93.2%(P < 0.001), and for patients with EBV DNA copy number > 4000 vs. < 4000 copies/mL were 83.5% vs.93.9%(P < 0.001). After adjusting for GTVnd, EBV DNA copy number, and T category in the Cox regression model, both GTVnd > 18.9 mL and EBV DNA copy number > 4000 copies/mL were significantly associated with poor prognosis(both P < 0.05). According to combination of GTVnd and EBV DNA copy number, all patients were divided into low-,moderate-, and high-risk groups, with the 5-year DMFS rates of 96.1,87.4, and 73.8%, respectively(P < 0.001). Multivariate analysis confirmed the prognostic value of this model for distant metastatic risk stratification(hazard ratio [HR],4.17; 95% confidence interval [CI] 2.34-7.59; P < 0.001).Conclusions: GTVnd and serum EBV DNA copy number are independent prognostic factors for predicting distant metastasis in NPC patients with N1 disease. The prognostic model incorporating GTVnd and EBV DNA copy number may improve metastatic risk stratification for this group of patients. | Ji‑Jin Yao Guan‑Qun Zhou Ya‑Qin Wang Si‑Yang Wang Wang‑Jian Zhang Ya‑Nan Jin Fan Zhang Li Li Li‑Zhi Liu Zhi‑Bin Cheng Jun Ma Zhen‑Yu Qi | 2017 | Chinese Journal of Cancer2017，36，12： | 9 |
| 11 | XPA A23G polymorphism is associated with the elevated response to platinum-based chemotherapy in advanced non-small cell lung cancer显示文摘DNA 修理能力(DRC ) 向基于铂的化疗与癌症房间的敏感被相关。我们假设那在 DNA 的基因多型性修理基因 XPA (干皮病 pigmentosum 组 A )和 XPG (干皮病 pigmentosum 组 G )( ERCC5 ,切除修理跨互补的组 5 ),它在 DNA 修理效率导致内部个人的差别,可以在先进非小的房间肺癌症( NSCLC )预言临床的反应到铂代理人病人。在这研究,我们发现 XPA A23G 多型性的 A G 变化显著地增加了反应到基于铂的化疗。在 XPG His46His 的多型性与减少的治疗回答被联系,但是不是统计上重要的。 | Jifeng Feng Xinchen Sun Ning Sun Shukui Qin Fan Li Hongyan Cheng Baoan Chen YuanDong Cao Jun Ma Lu Cheng Zuhong Lu Jiazhong Ji Yingfeng Zhou | 2009 | Acta Biochimica et Biophysica Sinica2009，41，5： | 8 |
| 12 | Predictors of adherence to home-based cardiac rehabilitation program among coronary artery disease outpatients in China显示文摘Background Cardiac rehabilitation (CR) has proven beneficial for patients with coronary artery disease. However, adherence to CR programs is the key to the health improvement in those patients. Identifying predictors for adherence, which is very much unknown in China, would be valuable for effective rehabilitation. This study aims to determine the adherence to home-based CR programs in Chinese coronary artery disease patients and determine predictors of adherence. Methods The current study included 1033 outpatients with coronary heart disease in the First Medical Center of Chinese PLA General Hospital in Beijing from July 2015 to June 2017. Participants were given an exercise prescription and took part in home-based exercise training lasting for 3–24 months. A questionnaire was used to evaluate the completion of the CR program, understanding of the program, motivation of the patients, and family/peer support. Results Two thirds of the patients adhered well to the home-based CR program. Elder patients (≥ 65-year-old) adhere to the program better, while men adhered better than women. Patients who used to exercise (B = 6.756, P < 0.001), understood the program (B = 0.078, P = 0.002), with stronger motivation to participate (B = 0.376, P < 0.001), and received better family support (B = 0.487, P < 0.001) also adhere better to the program. Conclusions Understanding the program, self-motivation of patients, and family support help to keep patients engaged in a home-based CR program. Improvement of family support by educating both patients and families may be helpful in improving adherence to home-based CR programs. | Cheng GE Jing MA Yong XU Ya-Jun SHI Cheng-Hui ZHAO Ling GAO Jing BAI Yu WANG Zhi-Jun SUN Jun GUO Yun-Dai CHEN | 2019 | Journal of Geriatric Cardiology2019，16，10： | 8 |
| 13 | Arsenic trioxide promotes senescence and regulates the balance of adipogenic and osteogenic differentiation in human mesenchymal stem cells显示文摘砷三氧化物(ATO ) 能在肿瘤房间作为反肿瘤药导致区别和 apoptosis。间充质的干细胞(MSC ) 在骨头髓的造血作用起重要作用。许多报告证明了 MSC adipogenic 和 osteogenic 区别的混乱发生在一些疾病。然而,关于 MSC 上的 ATO 的效果的报告是有限的。在这研究,我们发现 1 M ATO 主要通过 p21 支持了 MSC 老朽,尽管它没在这剂量在 apoptosis 上有效果。而且, ATO 支持了 adipogenic 区别,但是在 MSC 禁止了 osteogenic 区别。我们的学习也显示出那 CCAAT/enhancer-binding 蛋白质 alpha C/EBP 和 peroxisome 激活 proliferator 的受体 gamma PPAR 可能涉及 ATO 导致的 adipogenic 和 osteogenic 区别的规定。我们的结果显示 ATO 可以由影响骨头髓微型环境施加反肿瘤效果。而且,它可以调整 MSC 的 adipogenic 和 osteogenic 区别。 | Huanchen Cheng Lin Qiu Hao Zhang Mei Cheng Wei Li Xuefei Zhao Keyu Liu Lei Lei Jun Ma | 2011 | Acta Biochimica et Biophysica Sinica2011，43，3： | 8 |
| 14 | Efficacy and safety of Shenyankangfu Tablet,a Chinese patent medicine,for primary glomerulonephritis:A multicenter randomized controlled trial显示文摘Background:Shenyankangfu Tablet(SYKFT)is a Chinese patent medicine that has been used widely to decrease proteinuria and the progression of chronic kidney disease.Objective:This trial compared the efficacy and safety of SYKFT,for the control of proteinuria in primary glomerulonephritis patients,against the standard drug,losartan potassium.Design,setting,participants and intervention:This was a multicenter,double-blind,randomized,controlled clinical trial.Primary glomerulonephritis patients,aged 18-70 years,with blood pressure≤140/90 mmHg,estimated glomerular filtration rate(eGFR)>45 mL/min per 1.73 ㎡,and 24-hour proteinuria level of 0.5-3.0 g,were recruited in 41 hospitals across 19 provinces in China and were randomly divided into five groups:SYKFT,losartan potassium 50 mg or 100 mg,SYKFT plus losartan potassium 50 mg or 100 mg.Main outcome measu res:The primary outcome was change in the 24-hour proteinuria level,after 48 weeks of treatment.Results:A total of 735 participants were enrolled.The percent decline of urine protein quantification in the SYKFT group after 48 weeks was 8.78%±2.56%(P=0.006)more than that in the losartan 50 mg group,which was 0.51%±2.54%(P=1.000)less than that in the losartan 100 mg group.Compared with the losartan potassium 50 mg group,the SYKFT plus losartan potassium 50 mg group had a 13.39%±2.49%(P<0.001)greater reduction in urine protein level.Compared with the losartan potassium 100 mg group,the SYKFT plus losartan potassium 100 mg group had a 9.77%±2.52%(P=0.001)greater reduction in urine protein.With a superiority threshold of 15%,neither was statistically significant.eGFR,serum creatinine and serum albumin from the baseline did not change statistically significant.The average change in TCM syndrome score between the patients who took SYKFT(-3.00[-6.00,-2.00])and who did not take SYKFT(-2.00[-5.00,0])was statistically significant(P=0.003).No obvious adverse reactions were observed in any group.Conclusion:SYKFT decreased the proteinuria and improved the TCM syndrome scores of primary glomerulonephritis patients,with no change in the rate of decrease in the eGFR.SYKFT plus losartan potassium therapy decreased proteinuria more than losartan potassium therapy alone.Trial registration number:NCT02063100 on ClinicalTrials.gov. | Jie Wu Shu-wei Duan Hong-tao Yang Yue-yi Deng Wei Li Ya-ni He Zhao-hui Ni Yong-li Zhan Shan Lin Zhi-yong Guo Jun Zhu Jing-ai Fang Xu-sheng Liu Li-hua Wang Rong Wang Nian-song Wang Xiao-hong Cheng Li-qun He Ping Luo Shi-ren Sun Ji-feng Sun Ai-ping Yin Geng-ru Jiang Hong-yu Chen Wen-hu Liu Hong-li Lin Meng Liang Lu Ma Ming Chen Li-qun Song Jian Chen Qing Zhu Chang-ying Xing Yun Li Ji-ning Gao Rong-shan Li Ying Li Hao Zhang Ying Lu Qiao-ling Zhou Jun-zhou Fu Qiang He Guang-yan Cai Xiang-mei Chen | 2021 | Journal of Integrative Medicine2021，19，2： | 8 |
| 15 | Research on KOH/La-Ba-Al_2O_3 catalysts for biodiesel production via transesterification from microalgae oil显示文摘Alumina supports modified by lanthanum(La)and barium(Ba)were prepared by peptization.Catalysts with different KOH contents supported on modified alumina were prepared by impregnation method.Various techniques,including N2 adsorption-desorption(Brunauer-Emmet-Teller method,BET),X-ray diffraction(XRD),scanning electron microscopy(SEM),and fourier transform infrared absorption spectroscopy(FT-IR). Catalytic activity for microalgae oil conversion to methyl ester via transesterification was evaluated and analyzed by GC-MS and GC.BET results showed that the support possessed high specific surface area,suitable pore volume and pore size distribution.Activity results indicated that the catalyst with 25 wt%KOH showed the best activity for microalgae oil conversion.XRD and SEM results revealed that Al-O-K compound was the active phase for microalgae oil conversion.The agglomeration and changing of pore structure should be the main reasons for the catalyst deactivation when KOH content was higher than 30 wt%. | Xiaoyu Zhang Qing Ma Bibo Cheng Jun Wang Jinshan Li Fude Nie | 2012 | Journal of Natural Gas Chemistry2012，21，6： | 7 |
| 16 | An-Luo-Hua-Xian Pill Improves the Regression of Liver Fibrosis in Chronic Hepatitis B Patients Treated with Entecavir显示文摘Background and Aims:Chronic hepatitis B(CHB)can cause liver fibrosis and lead to cirrhosis and cancer.As the effectiveness of antiviral therapy to reverse liver fibrosis is limited,We aimed to evaluate the effect of An-Luo-Hua-Xian pill(ALHX)on fibrosis regression in CHB patients treated with entecavir(ETV).Methods:Treatment-naïve patients with CHB were randomly treated with ETV alone or combined with ALHX(ETV+ALHX)between October 1,2013 and December 31,2020.Demographic,laboratory,and liver histology data before and after 78 weeks of treatment were collected.The Ishak fibrosis score(F)was used and fibrosis regression required a decrease in F of≥1 after treatment.Results:A total of 780 patients were enrolled,and 394 with a second liver biopsy after treatment were included in the per-protocol population,132 in ETV group and 262 in ETV+ALHX group.After 78 weeks of treatment,the fibrosis regression rate in the ETV+ALHX group was significantly higher than that of the ETV group at baseline F≥3 patients:124/211(58.8%)vs.45/98(45.9%),p=0.035.The percentage of patients with a decreased liver stiffness measurement(LSM)was higher in the ETV+ALHX group:156/211(73.9%)vs.62/98(63.%),p=0.056.Logistic regression analysis showed that ETV combined with ALHX was associated with fibrosis regression[odds ratio(OR)=1.94,p=0.018],and a family history of hepatocellular carcinoma was on the contrary.(OR=0.41,p=0.031).Conclusions:ETV combined with ALHX increased liver fibrosis regression in CHB patients. | Yi-Qi Liu Chi Zhang Jia-Wen Li Li-Hua Cao Zhan-Qing Zhang Wei-Feng Zhao Qing-Hua Shang Da-Zhi Zhang An-Lin Ma Qing Xie Hong-Lian Gui Guo Zhang Ying-Xia Liu Jia Shang Shi-Bin Xie Jun Li Xu-Qing Zhang Zhi-Qiang Zou Yu-Ping Chen Zong Zhang Ming-Xiang Zhang Jun Cheng Fu-Chun Zhang Li-Hua Huang Jia-Bin Li Qing-Hua Meng Hai-Bin Yu Yu-Qiang Mi Yan-Zhong Peng Zhi-Jin Wang Li-Ming Chen Fan-Ping Meng Wan-Hua Ren Lang Bai Yi-Lan Zeng Rong Fan Xian-Zhi Lou Wei-Feng Liang Hui Liu Hui Zhuang Hong Zhao Gui-Qiang Wang | 2023 | Journal of Clinical and Translational Hepatology2023，11，2： | 7 |
| 17 | Accumulation of cadmium and copper by female Oxya chinensis (Orthopera: Acridoidea) in soil-plant-insect system显示文摘One purpose of this research is to present accumulation of cadmium(Cd) and copper(Cu) by female Oxya chinensis(Orthopera: Acridoidea) in a simulated s oil-plant-insect ecosystem treated with Cd. Fourth-instar nymphs of O. chinensis had been fed on wheat(Triticum aestivum) seedlings contaminated with Cd and Cu for one month. In the ecosystem, the Cd concentration in wheat seedlings rose gr eatly with the increasing of Cd in the soil, but the Cu concentration in wheat s eedlings was not found elevated. There was a highly significant difference(P<0. 05) in Cd concentrations of wheat seedlings and not any significant difference(P >0.05) in Cu concentrations of wheat seedlings. The Cd and Cu concentration in different body part-head, thorax, abdomen, and hind femur, varied under differen t Cd concentrations in soil. There were significant differences(P<0.05) in the four parts of Cd and Cu accumulations with all treatments. The order of Cd accum ulation was thorax>abdomen>head>hind femur and the Cu was abdomen>thorax>he ad>hind femur. The results indicated that Cd and Cu were accumulated from the s oil to grasshoppers through the plant; that is to say, Cd and Cu in environment could be transported to animal or human via food chain. | LI Li-jun LIU Xue-mei DUAN Yi-hao GUO Ya-ping CHENG Bin GUO Jun XI Yu-ying MA En-bo | 2006 | Journal of Environmental Sciences2006，18，2： | 7 |
| 18 | A new cassane diterpenoid lactone from the seed of Caesalpinia minax显示文摘新 cassane diterpenoid 内酯从 Caesalpinia 古代希腊的金额单位 x 的种子被孤立。根据光谱证据,它的结构作为 12 α 被建立; -methoxyl, 5 α, 14 β -dihydroxy-1α, 6 α, 7 β -triacetoxycass-13(15)-en-16, 12-olide。 | Yan Cheng Li Yan Ma Jian Hua Miao Xu Dong Xu Jing Quan Yuan Jun Shan Yang | 2009 | Chinese Chemical Letters2009，20，4： | 7 |
| 19 | Multicenter Clinical Study for Evaluation of Efficacy and Safety of Transdermal Fentanyl Matrix Patch in Treatment of Moderate to Severe Cancer Pain in 474 Chinese Cancer Patients显示文摘Objective: Although a new matrix formulation fentanyl has been used throughout the world for cancer pain management, few data about its efficacy and clinical outcomes associated with its use in Chinese patients have been obtained. This study aimed to assess the efficacy and safety of the new system in Chinese patients with moderate to severe cancer pain. Methods: A total of 474 patients with moderate to severe cancer pain were enrolled in this study and were treated with the new transdermal fentanyl matrix patch (TDF) up to 2 weeks. All the patients were asked to record pain intensity, side effects, quality of life (QOL), adherence and global satisfaction. The initial dose of fentanyl was 25 ?g/h titrated with opioid or according to National Comprehensive Cancer Network (NCCN) guidelines. Transdermal fentanyl was changed every three days. Results: After 2 weeks. The mean pain intensity of the 459 evaluated patients decreased significantly from 5.63?1.26 to 2.03?1.46 (P<0.0001). The total remission rate was 91.29%, of which moderate remission rate 53.16%, obvious remission rate 25.49% and complete remission rate 12.64%. The rate of adverse events was 33.75%, 18.78% of which were moderate and 3.80% were severe. The most frequent adverse events were constipation and nausea. No fatal events were observed. The quality of life was remarkably improved after the treatment (P<0.0001). Conclusion: The new TDF is effective and safe in treating patients with moderate to severe cancer pain, and can significantly improve the quality of life. | Yu-lin Zhu Guo-hong Song Duan-qi Liu Xi Zhang Kui-feng Liu Ai-hua Zang Ying Cheng Guo-chun Cao Jun Liang Xue-zhen Ma Xin Ding Bin Wang Wei-lian Li Zuo-wei Hu Gang Feng Jiang-jin Huang Xiao Zheng Shun-chang Jiao Rong Wu Jun Ren | 2011 | Chinese Journal of Cancer Research2011，23，4： | 6 |
| 20 | A CRISPR evolutionary arms race: structural insights into viral anti-CRISPR/Cas responses显示文摘 | Jiuyu Wang Jun Ma Zhi Cheng Xu Meng Lilan You Min Wang Xinzheng Zhang Yanli Wang | 2016 | Cell Research2016，26，10： | 6 |
您所在的机构暂未开通此部分的功能，请联系管理员