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| 1 | METTL3-mediated N^6-methyladenosine mRNA modification enhances long-term memory consolidation显示文摘 | Zeyu Zhang Meng Wang Dongfang Xie Zenghui Huang Lisha Zhang Ying Yang Dongxue Ma Wenguang Li Qi Zhou Yun-Gui Yang Xiu-Jie Wang | 2018 | Cell Research2018，28，11： | 29 |
| 2 | Preparation and hydrogen gas sensitive characteristics of highly ordered titania nanotube arrays显示文摘In this paper, we report the growth and characteristics of titania nanotube arrays prepared by anodic oxidation and then annealed in an oxygen atmosphere at 500℃. The titania nanotube arrays presented high sensitivity to hydrogen gas. The crystalline phase of the samples was checked by X-ray diffraction (XRD). The differences in the nanotubes morphology attributed to the etched samples due to anodiza- tion potential, reaction time and the electrolyte concentration were analyzed by scanning electron mi- croscopy (SEM). The gas sensitive parameters of the samples were obtained from resistance, the re- sponse time and the recovery time at different temperatures. | JI HuiMing LU HuiXiang MA DongFang YU JianJun MA ShiCai | 2008 | Chinese Science Bulletin2008，53，9： | 7 |
| 3 | Pathological changes in the lungs and lymphatic organs of 12 COVID-19 autopsy cases显示文摘Systematic autopsy and comprehensive pathological analyses of COVID-19 decedents should provide insights into the disease characteristics and facilitate the development of novel therapeutics.In this study,we report the autopsy findings from the lungs and lymphatic organs of 12 COVID-19 decedents—findings that evaluated histopathological changes;immune cell signature and inflammatory factor expression in the lungs,spleen and lymph nodes.Here we show that the major pulmonary alterations included diffuse alveolar damage,interstitial fibrosis and exudative inflammation featured with extensive serous and fibrin exudates,macrophage infiltration and abundant production of inflammatory factors(IL-6,IP-10,TNFo?and IL-I f).The spleen and hilar lymph nodes contained lesions with tissue structure disruption and immune cell dysregulation,including lymphopenia and macrophage accumulation.These findings provide pathological evidence that links injuries of the lungs and lymphatic organs with the fatal systematic respiratory and immune malfunction in critically ill COVID-19 patients. | Qian Liu Yu Shi Jun Cai Yaqi Duan Rongshuai Wang Hongyan Zhang Qiurong Ruan Jiansha Li Lei Zhao Yifang Ping Rong Chen Liang Ren Xiaochun Fei Heng Zhang Rui Tang Xi Wang Tao Luo Xindong Liu Xuequan Huang Zhenhua Liu Qilin Ao Yong Ren Jing Xiong Zhicheng He Haibo Wu Wenjuan Fu Pengnan Zhao Xinwei Chen Guoqiang Qu Yunyun Wang Xi Wang Jia Liu Dongfang Xiang Sanpeng Xu Xiaowei Zhou Qingrui Li Jinghong Ma Heng Li Jie Zhang Sizhe Huang Xiaohong Yao Yiwu Zhou Chaofu Wang Dingyu Zhang Guoping Wang Liang Liu Xiu-Wu Bian | 2020 | National Science Review2020，7，12： | 6 |
| 4 | Effects of trigonelline inhibition of the Nrf2 transcription factor M vitro on Echmococcus granulosus显示文摘 | Wenjuan Qin Dongfang Guan Rongji Ma Rentan Yang Guoqiang Xing Hongjuan Shi Guangyao Tang Jiajie Li Hailong Lv Yufeng Jiang | 2017 | Acta Biochimica et Biophysica Sinica2017，49，8： | 4 |
| 5 | Sensitivity of Fusarium graminearum to Carbendazim and Prochloraz显示文摘[Objective]The paper was to understand the resistance of Fusarium graminearum to carbendazim and prochloraz in the main wheat producing areas in Hubei Province.[Method] Totally 350 F. graminearum strains isolated in 2014 were determined to clear their sensitivity to carbendazim and prochloraz. [Result]All isolates were sensitive to carbendazim and prochloraz in Hubei Province,and carbendazim was still valuable in controlling Fusarium head blight. The control effect of prochloraz was better than that of carbendazim,and the combination of prochloraz and carbendazim at the proportion of 1∶ 7 received the best control effect.[Conclusion]Combination of chemical agents will occupy a more and more important position in future prevention and control against Fusarium head blight. | Ma Dongfang Huang Shi Zhang Peng Sun Cai Huang Wendi Li Guangjun Zhang Changqing Fang Zhengwu | 2017 | Plant Diseases and Pests2017，8，1： | 2 |
| 6 | On the measurements of individual particle properties via compression and crushing显示文摘An experimental study is presented to measure the elastic,yielding,and crushing properties of individual particles under compression using substrates made of aluminum alloy,stainless steel,and sapphire.Carefully selected,highly spherical individual Ottawa sand particles of 0.75e1.1 mm in nominal diameter were compressed between two smooth substrates,and the loadedeformation curves were analyzed by Hertz elastic contact theory to derive their reduced modulus and Young’s modulus as well as yielding and crushing strengths,which vary significantly with the type of substrate materials.Further analysis of the yielding and plastic deformation at the particle-substrate contact shows that the yield strength or hardness of the substrate materials dominates the local contact behavior and hence affects the measured apparent yielding and crushing strengths.The two softer substrates(aluminum alloy and stainless steel)actually lead to underestimated apparent shear yield strengths of quartz particles by 60.4%and 54.2%,respectively,which are actually the yielding of substrates,while the true particle yielding occurs in the sapphire-particle contact.Moreover,the two softer substrates cause much overestimated crushing strengths of the quartz particles by 50.4%and 36.4%,respectively.Selection of inappropriate substrate materials and inappropriate interpretation of the particle-substrate contact can lead to significant errors in the measured yielding and crushing strengths.It is recommended that single particle compression testing uses substrates with yield strength greater than that of the tested particles and result interpretation also considers the elastic and yielding behaviors of the substrates. | Chunlong Liu Fengyin Liu Jinliang Song Fuli Ma Dongfang Wang Guoping Zhang | 2021 | Journal of Rock Mechanics and Geotechnical Engineering2021，13，2： | 1 |
| 7 | Unraveling Passivation Mechanism of Imidazolium-Based Ionic Liquids on Inorganic Perovskite to Achieve Near-Record-Efficiency CsPbI_(2)Br Solar Cells显示文摘The application of ionic liquids in perovskite has attracted wide-spread attention for its astounding performance improvement of perovskite solar cells(PSCs).However,the detailed mechanisms behind the improvement remain mysterious.Herein,a series of imidazolium-based ionic liquids(IILs)with different cations and anions is systematically investigated to elucidate the passivation mechanism of IILs on inorganic perovskites.It is found that IILs display the following advantages:(1)They form ionic bonds with Cs^(+)and Pb^(2+)cations on the surface and at the grain boundaries of perovskite films,which could effectively heal/reduce the Cs^(+)/I−vacancies and Pb-related defects;(2)They serve as a bridge between the perovskite and the hole-transport-layer for effective charge extraction and transfer;and(3)They increase the hydrophobicity of the perovskite surface to further improve the stability of the CsPbI_(2)Br PSCs.The combination of the above effects results in suppressed non-radiative recombination loss in CsPbI_(2)Br PSCs and an impressive power conversion efficiency of 17.02%.Additionally,the CsPbI_(2)Br PSCs with IILs surface modification exhibited improved ambient and light illumination stability.Our results provide guidance for an indepth understanding of the passivation mechanism of IILs in inorganic perovskites. | Jie Xu Jian Cui Shaomin Yang Yu Han Xi Guo Yuhang Che Dongfang Xu Chenyang Duan Wenjing Zhao Kunpeng Guo Wanli Ma Baomin Xu Jianxi Yao Zhike Liu Shengzhong Liu | 2022 | Nano-Micro Letters2022，14，1： | 1 |
| 8 | 4-port digital isolator based on on-chip transformer显示文摘The design and fabrication results of a 4-port digital isolator based on an on-chip transformer for galvanic isolation are presented. An ON–OFF keying modulation scheme is used to transmit the digital signal. The proposed digital isolator is fabricated by the 0.18 μm CMOS process. A test chip can achieve a 1 MHz signal bandwidth, a 40 ns propagation delay, a 35.5 mW input power and a 50 mA drive output current. The proposed digital isolator is pin-compatible, of small volume and low power replacement for the common 4-port optocoupler. | Feng Zhang Ting Zhao Chunyu Ma Dongfang Pan | 2018 | Journal of Semiconductors2018，39，11： | 1 |
| 9 | Inhibitory Effects of Phenamacril, Tebuconazole and Their Mixtures on Fusarium graminearum in Wheat显示文摘Fusarium head blight caused by Fusarium graminearum is one of the most serious diseases in wheat production worldwide, which seriously affects the yield and quality of wheat. Wheat grains carrying the pathogen are poisonous to human and livestock health. With the long-term use of single chemical pesticide, the drug-resistance of F. graminearum is increasing day by day, and mixed agent is one of the effective strategies to improve the efficacy and delay the resistance. The mycelial growth rate method was used to determine the inhibition rates of phenamacril, tebuconazole and their mixtures(1∶1, 1∶3, 1∶5, 1∶7, 3∶1, 5∶1 and 7∶1). The synergistic coefficient(SR) was calculated by Wadley method, and the combined action types of the two agents were evaluated. The results showed that the EC_(50) of tebuconazole was 0.418 28 mg/L, and that of phenamacril was 0.489 8 mg/L; the optimum mixture ratio of phenamacril and tebuconazole was 1 ∶1, with the EC_(50) value of 0.053 74 and the synergistic coefficient of 4.2696, and the control effect of mixed agent was significantly better than that of single agent. It is feasible to control Fusarium head blight by mixing phenamacril and tebuconazole, providing a theoretical basis for development of new compound agents and effective control of Fusarium head blight. | Lei Cuiyu Yin Junliang Fang Zhengwu Wang Shuping Zhang Xing Ma Dongfang | 2018 | Plant Diseases and Pests2018，9，3： | 1 |
| 10 | Non-weight modules over the mirror Heisenberg-Virasoro algebra显示文摘In this paper,we study irreducible non-weight modules over the mirror Heisenberg-Virasoro algebra D,including Whittaker modules,U(Cd_(0))-free modules and their tensor products.More precisely,we give the necessary and sufficient conditions for the Whittaker modules to be irreducible.We determine all the D-module structures on U(Cd_(0)),and find the necessary and sufficient conditions for these modules to be irreducible.At last,we determine the necessary and sufficient conditions for the tensor products of Whittaker modules and U(Cd_(0))-free modules to be irreducible,and obtain that any two such tensor products are isomorphic if and only if the corresponding Whittaker modules and U(Cd_(0))-free modules are isomorphic.These lead to many new irreducible non-weight modules over D. | Dongfang Gao Yao Ma Kaiming Zhao | 2022 | Science China Mathematics2022，65，11： | 1 |
| 11 | Genome-wide Analysis of a Plant AT-rich Sequence and Zinc-binding Protein (PLATZ) in Triticum Aestivum显示文摘Plant AT-rich sequence and zinc-binding protein(PLATZ)is a plant transcription factor that has been studied in corn.PLATZ can non-specifically bind to sequences rich in A/T bases to induce transcriptional repression.It is involved in the regulation of dehydration tolerance in seeds.In this study,we performed bioinformatics analysis to identify and characterize wheat PLATZ(TaPLATZ)genes.We identified 49 wheat PLATZ genes by searching the wheat genome by using known PLATZ gene sequences from rice,Arabidopsis,and maize.Phylogenetic analysis on PLATZ gene sequences from different species was performed.We found that PLATZs could be divided into three groups.The chromosome(chr)distribution analysis revealed that the 49 identified wheat PLATZ genes are distributed in 15 chrs.Gene structure and motif analyses indicated that most PLATZ genes possess conserved exon/intron arrangements and motif compositions.Our analysis of transcriptional data indicated that several wheat PLATZ genes may play an important role in abiotic stress resistance given that they are expressed under salt stress.The results of qRT-PCR further confirmed that TaPLATZ is involved in plant abiotic stress and is also related to the cell differentiation of plant tissues.Our results lay the foundation for further studies on the function of the wheat PLATZ gene family. | Xiaohang He Minjie Liu Zhengwu Fang Dongfang Ma Yilin Zhou Junliang Yin | 2021 | Phyton-International Journal of Experimental Botany2021，90，3： | 1 |
| 12 | A Method of Signal Timing Optimization for Spillover Dissipation in Urban Street Networks显示文摘 | Dongfang Ma Dianhai Wang Yiming Bie Sun Di Wudhichai Assawinchaichote | 2013 | Mathematical Problems in Engineering2013，，： | 1 |
| 13 | Magmatic Evolution and Mineralization of Porphyry Copper-Gold Deposits in the Duolong Ore Concentration Area, Tibet显示文摘The Bangong Lake-Nujiang River metallogenic belt is located between the Qiangtang Block and Lhasa Block,and the Duolong ore concentration area is located in the western section of the Bangong Lake-Nujiang River metallogenic belt.Till now,several large and super large copper-gold deposits,such as Duobuza,Bolong, | ZHANG Hai MA Dongfang ZHANG Hong ZHU Xiangping | 2015 | Acta Geologica Sinica(English Edition)2015，89，5： | 1 |
| 14 | Inhibition Effect and Synergistic Effect of Prochloraz and Tebuconazole and Their Mixture on Fusarium graminearum显示文摘Wheat scab caused by Fusarium graminearum is increasingly severe in the middle and lower reaches of the Yangtze River region. With long-term use of single chemical pesticide,the drug resistance of F. graminearum is growing day by day. In order to reveal the inhibition effect and synergistic effect of prochloraz and tebuconazole and their mixture on F. graminearum,new compound agents for controlling wheat scab were developed. The inhibition effect and synergistic effect of prochloraz and tebuconazole mixed at seven different ratios on F. graminearum were studied. The results showed that the efficiency of the mixture was the best when the proportion of prochloraz and tebuconazole was 1:7; the EC50 was 0.145 36 and the synergistic coefficient was 1.853 9. The results provide a theoretical basis for development of new compound agents and effective control of wheat scab. | Zhang Xing Zhang Lin He Yiqin Lu Chen Fang Zhengwu Zhao Mingmin Zhu Yongxing Ma Dongfang | 2017 | Plant Diseases and Pests2017，8，6： | 0 |
| 15 | Elevated Kir2.1/nuclear N2ICD defines a highly malignant subtype of non-WNT/SHH medulloblastomas显示文摘Medulloblastoma(MB)is one of the most common childhood malignant brain tumors(WHO grade IV),traditionally divided into WNT,SHH,Group 3,and Group 4 subgroups based on the transcription profiles,somatic DNA alterations,and clinical outcomes.Unlike WNT and SHH subgroup MBs,Group 3 and Group 4 MBs have similar transcriptomes and lack clearly specific drivers and targeted therapeutic options.The recently revised WHO Classification of CNS Tumors has assigned Group 3 and 4 to a provisional non-WNT/SHH entity.In the present study,we demonstrate that Kir2.1,an inwardly-rectifying potassium channel,is highly expressed in non-WNT/SHH MBs,which promotes tumor cell invasion and metastasis by recruiting Adam10 to enhance S2 cleavage of Notch2 thereby activating the Notch2 signaling pathway.Disruption of the Notch2 pathway markedly inhibited the growth and metastasis of Kir2.1-overexpressing MB cell-derived xenograft tumors in mice.Moreover,Kir2.1^(high)/nuclear N2ICD^(high)MBs are associated with the significantly shorter lifespan of the patients.Thus,Kir2.1^(high)/nuclear N2ICD^(high)can be used as a biomarker to define a novel subtype of non-WNT/SHH MBs.Our findings are important for the modification of treatment regimens and the development of novel-targeted therapies for non-WNT/SHH MBs. | Yan-Xia Wang Haibo Wu Yong Ren Shengqing Lv Chengdong Ji Dongfang Xiang Mengsi Zhang Huimin Lu Wenjuan Fu Qing Liu Zexuan Yan Qinghua Ma Jingya Miao Ruili Cai Xi Lan Bin Wu Wenying Wang Yinhua Liu Dai-Zhong Wang Mianfu Cao Zhicheng He Yu Shi Yifang Ping Xiaohong Yao Xia Zhang Peng Zhang Ji Ming Wang Yan Wang Youhong Cui Xiu-Wu Bian | 2022 | Signal Transduction and Targeted Therapy2022，7，4： | 0 |
| 16 | PTPN12的晶体结构和底物特异性显示文摘PTPN12是一个重要的肿瘤抑制因子,并参与调控很多重要的生理过程。作为磷酸酶,PTPN12有很多底物,但对其底物的特异性缺乏了解。 | hui li fan yang chunhua liu peng xiao yunfei xu zonglai liang chuan liu hongmei wang wenjun wang wenshuai zheng wei zhang xiaoyun ma dongfang he xiaoyuan song fuai cui zhigang xu fan yi 孙金鹏 于晓 | 2017 | 科学新闻2017，0，4： | 0 |
| 17 | Dynamic response of a Q&P steel to high-strain-rate tension显示文摘The experimental study on the volume fraction of retained austenite for QP980CR steel under high-strain-rate tension is briefly described.An interrupted tensile split Hopkinson bar(TSHB)is developed to control the elongation of specimens.The QP980CR steel samples recovered from the interrupted TSHB tests are investigated using synchrotron X-ray diffraction(XRD)to analyze the effects of strain and strain rate on the martensitic transformation of retained austenite.A constitutive model of QP980CR steel coupling with the transformation-induced plasticity(TRIP)effect is presented based on Delannay’s mean-field modeling.The stress–strain curves of quasi-static and dynamic tensile tests for QP980CR steel are compared with the results predicted by the presented constitutive model.The diffuse necking of QP980CR steel sheet specimens in TSHB tests is analyzed using Batra and Wei’s instability criterion and the presented constitutive model.The effects of strain rate and temperature on the dynamic tensile fracture strain of QP980CR steel are also given. | Huanran Wang Wenchao Zhang Dongfang Ma Bohan Ma Danian Chen Xin Yang Chunlei Fan | 2017 | Acta Mechanica Solida Sinica2017，30，5： | 0 |
| 18 | Protein-based biomaterials for combating viral infections:Current status and future prospects for development显示文摘The outbreak of viral infections are serious threat to human life and health.However,there remains to be a lack of effective treatments and prophylactic measures against some viral infections.Additionally,there are numerous challenges in developing vaccines and antiviral drugs(e.g.,antibodies and protein inhibitors),such as low immunogenicity of vaccines,difficulties in storing vaccines,instability and easy degradation of protein drugs,and lack of drug selectivity.Protein-based biomaterials can interact with antiviral drugs or vaccines to achieve synergistic or enhanced effects,making them a promising antiviral tool with many advantages.Silk fibroin has the potential to stabilize liquid vaccines at room temperature.Elastin-like polypeptide modification can improve the stability and yield of virus-neutralizing antibodies.Drugs in combination withβ-casein or serum albumin(SA)has good prospects in treating human immunodeficiency virus(HIV)infections.Moreover,the greatest value of SA as a protein-based antiviral material lies in its ability to target the liver and macrophages.In the future,combination with SA(direct conjugation or encapsulation with drugs)may be a better treatment strategy for viral hepatitis and HIV infections because it leads to fewer adverse reactions.In addition,selfassembling protein nanoparticles(SApNPs)are found to improve vaccine immunogenicity.The combination of multiple viral immunogens and multiple SApNPs produces different promising vaccine candidates,thus highlighting the value of SApNPs.This review aimed to discuss the current status and future prospects for the development of protein-based biomaterials to combat viral infections. | Yongyue Han Juanli Pan Yanhong Ma Dongfang Zhou Wei Xu | 2022 | Biosafety and Health2022，4，2： | 0 |
| 19 | Parametric generation and phase locking of multiple sidebands in the regime of full-back-conversion显示文摘Parametric interaction allows both forward and backward energy transfers among the three interacting waves.The back-conversion effect is usually detrimental when unidirectional energy transfer is desired.In this theoretical work,we manifest that the back-conversion effect underpins the direct generation of the picosecond pulse train without the need for a laser resonator.The research scenario is an optical parametric amplification(OPA)that consists of a second-order nonlinear medium,a quasi-continuous pump laser and a sinusoidal amplitude-modulated seed signal.The back-conversion of OPA can transfer the modulation peaks(valleys)of the incident signal into output valleys(peaks),which inherently induces spectral sidebands.The generation of each sideband is naturally accompanied with a phase shift of±π.In the regime of full-back-conversion,the amount and amplitude of the sidebands reach the maximum simultaneously,and their phase constitutes an arithmetic sequence,leading to the production of a picosecond pulse train.The generated picosecond pulse train can have an ultrahigh repetition rate of 40 GHz or higher,which may facilitate ultrafast applications with ultrahigh speed. | Wenhao Wang Yudong Tao Jingui Ma Jing Wang Peng Yuan Dongfang Zhang Liejia Qian | 2023 | High Power Laser Science and Engineering2023，11，2： | 0 |
| 20 | Isolation of Antagonistic Bacteria against Fusarium graminearum and Its Antagonistic Activity显示文摘[Objective] To develop biological control resources of endophytic bacteria in wheat,the bacteria with antagonistic effect against Fusarium graminearum were screened and their antagonistic activity was studied. [Method] The endophytic bacteria of wheat with antagonistic effect were screened using plate confrontation method; the antagonistic bacteria were identified through physiological and biochemical characteristics and 16 S r DNA sequence analysis; the antagonistic spectrum of antagonistic bacteria was studied using plate confrontation method. [Result]The antagonistic bacterium XY-3 was isolated from wheat leaves,and was identified as Bacillus amyloliquefaciens according to the physiological and biochemical characteristics and 16 S r DNA sequence analysis. [Conclusion] XY-3 had antagonistic effect against four kinds of common pathogenic fungi,presenting broad spectrum antagonistic activity against plant pathogenic fungi. | Sun Cai Zhang Peng Huang Shi Li Hongyan Ma Dongfang Zhang Changqing | 2016 | Plant Diseases and Pests2016，7，5： | 0 |
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