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| 1 | T-regulatory lymphocytes in peripheral blood of gastric and colorectal cancer patients显示文摘AIM: To assess the absolute number of T-regulatory cells (Tregs; CD4+CD25+Foxp3+) in the peripheral blood of gastric and colorectal cancer patients. METHODS: We enrolled 70 cancer patients (33 gastric cancer, 37 colorectal cancer) and 17 healthy volunteers. The CD3+CD4+ lymphocytes and CD4+CD25+Foxp3+ Tregs in the peripheral blood were analyzed with flow cytometry. The absolute numbers of Tregs were calculated based on the CD4+CD25+Foxp3+ cells percent-age of CD3+CD4+ cells and the absolute numbers of CD3+CD4+ cells per microliter. RESULTS: The mean number of CD4+CD25+Foxp3+ cells per microliter in colorectal cancer patients was 15.7 (SD: 21.8), for gastric cancer patients 12.2 (SD: 14.3), and for controls 17.5 (SD: 11.4). The absolute number of Tregs was significantly lower in gastric cancer patients than in controls (P = 0.026). There was no statistically significant difference for gastric vs colorectal cancer or colorectal cancer vs controls. The absolute number of Tregs was also significantly depressed in N+ vs Ncancer patients [22.0 (27.7) vs 10.1 (9.0), P = 0.013], and in the subgroup of gastric cancer patients [30.3 (27.6) vs 9.6 (8.0), P = 0.003]. No statistical difference was observed in the proportion of Tregs in the CD4+ population between the groups. CONCLUSION: The absolute number of Tregs in peripheral blood of gastric cancer but not colorectal cancer patients was significantly decreased in comparison with that in healthy controls. | Antoni M Szczepanik Maciej Siedlar Marek Sierzega Dominika Goroszeniuk Karolina Bukowska-Strakova Antoni Czupryna Jan Kulig | 2011 | World Journal of Gastroenterology2011，17，3： | 5 |
| 2 | Is the pain in chronic pancreatitis of neuropathic origin? Support from EEG studies during experimental pain显示文摘AIM: To prove the hypothesis that patients with chronic pancreatitis would show increased theta activity during painful visceral stimulation. METHODS: Eight patients and 12 healthy controls underwent an experiment where the esophagus was electrically stimulated at the pain threshold using a nasal endoscope. The electroencephalogram (EEG) was recorded from 64 surface electrodes and 'topographic matching pursuit' was used to extract the EEG information in the early brain activation after stimulation. RESULTS: A major difference between controls and patients were seen in delta and theta bands, whereas there were only minor differences in other frequency bands. In the theta band, the patients showed higher activity than controls persisting throughout the 450 ms of analysis with synchronous brain activation betweenthe channels. The main theta components oscillated with 4.4 Hz in the patients and 5.5 Hz in the controls. The energy in the delta (0.5-3.5 Hz) band was higher in the controls, whereas the patients only showed scattered activity in this band. CONCLUSION: The differences in the theta band indicate that neuropathic pain mechanisms are involved in chronic pancreatitis. This has important implications for the understanding and treatment of pain in these patients, which should be directed against drugs with effects on neuropathic pain disorders. | AsbjФrn M Drewes Maciej Gratkowski Saber AK Sami Georg Dimcevski Peter Funch-Jensen Lars Arendt-Nielsen | 2008 | World Journal of Gastroenterology2008，14，25： | 4 |
| 3 | Glucagon-like peptide-1 receptor imaging with [Lys 40 (Ahx-HYNIC- 99m Tc/EDDA)NH 2 ]-exendin-4 for the detection of insulinoma显示文摘 | Anna Sowa-Staszczak Dorota Pach Renata Miko?ajczak Helmut M?cke Agata Jabrocka-Hybel Agnieszka Stefańska Monika Tomaszuk Barbara Janota Aleksandra Gilis-Januszewska Maciej Ma?ecki Grzegorz Kamiński Aldona Kowalska Jan Kulig Andrzej Matyja Czes?aw Osuch Al | 2013 | European Journal of Nuclear Medicine and Molecular Imaging2013，，4： | 2 |
| 4 | Genetics of type2diabetes mellitus显示文摘 | Maciej T M | 2005 | Diabetes Res clin Pratt2005，68，： | 1 |
| 5 | Comparison of LaC13 : Ce and NaI (TI) Scintillators in -ray Spectrometry 显示文摘 | Marcin B Marek M Maciej K | 2005 | Nuclear Instruments and Methods in Physics Research2005，，： | 1 |
| 6 | Solubility of pyromorphite Pb5 (P04 )3 Cl-mimetite Pb5 ( As04 )3 Cl solid solution series显示文摘 | Justyna F Maciej M Tomasz B | 2011 | Geochimica et Cosmochimica Acta2011，75，7： | 1 |
| 7 | High-speed optical coherence tomography:ba- sics and applications显示文摘 | Maciej M | 2010 | Applied Optics2010，49，16： | 1 |
| 8 | Modulation of the anti-tumor immune response by complement显示文摘 | Maciej M Markiewsk I Robert A et a1 | 2008 | NatImmunol2008，9，11： | 1 |
| 9 | Deletion and insert operations in Voronoi/Delaunay methods and applications显示文摘 | ABOLFAZL M CHRISTOPHER G MACIEJ D | 2003 | Computers & Geosciences2003，23，： | 1 |
| 10 | Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells显示文摘 | LIZA K K MACIEJ K MATHEW M | 2003 | BMC Cancer2003，3，1： | 1 |
| 11 | Water-redispersible low-Tg acrylic powders for the modification of hydraulic binder compositions显示文摘 | Leo M Saija Maciej Uminski | 1999 | Journal of Applied Polymer Science1999，71，： | 1 |
| 12 | Cycle basis interpolation theorems 显示文摘 | FRANK Harary ELZBIETA Kolasinska MACIEJ M Syslo | 1985 | Annals of Discrete Mathematics1985，27，： | 1 |
| 13 | Inhibition of angiogenesis by IL-32: Possible role in asthma显示文摘 | Norbert Meyer Janine Christoph Heidi Makrinioti Philippe Indermitte Claudio Rhyner Michael Soyka Thomas Eiwegger Maciej Chalubinski Kerstin Wanke Hiroyuki Fujita Paulina Wawrzyniak Simone Bürgler Sherrie Zhang Mübeccel Akdis Günter Menz Cezmi Akdis | 2012 | The Journal of Allergy and Clinical Immunology2012，，4： | 1 |
| 14 | Hydrogel control of xylemhydraulic resistance in plants显示文摘 | Maciej A Z Peter J M Holbrook N M | | ProQuest Biology Journals Science0，1291，： | 1 |
| 15 | Comparison of LaCl3:Ce and NaI(TI)scintillators in γ-ray spectrometry显示文摘 | MARCIN B MAREK M MACIEJ K | 2005 | Nuclear Instruments and Methods in Physics Research A2005，537，： | 1 |
| 16 | Training neural network classifiers for medical decision making: the effects of imbalanced datasets on classification perfor- mance显示文摘 | MACIEJ A M PIOTR A H JACK M Z | 2008 | Neural Networks2008，21，2： | 1 |
| 17 | Laparoscopic splenectomy in children-A multicenter experience显示文摘 | Maciej M Dariusz P Wojciech K | 2008 | J Pediatr Surg2008，43，5： | 1 |
| 18 | Benign paroxysmal vertigo of childhood显示文摘 | JOZEF M MACIEJ P KRZYSZTOF D | 2007 | Otolaryngol2007，61，： | 1 |
| 19 | Deletion and insert Operations in voronoi/delaunay methods and applications显示文摘 | Mostafavi M A Gold C P Maciej Dakowicz | 2003 | Computers & Geosciences2003，23，4： | 1 |
| 20 | Electrochemically prepared silver nanoflakes and nanowires显示文摘 | MACIEJ M | 2004 | Elecrochemisry Communication2004，6，4： | 1 |
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