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| 1 | Genes associated with testicular germ cell tumors and testicular dysgenesis in patients with testicular microlithiasis显示文摘阴囊的 microlithiasis (TM ) 是阴囊的 dysgenesis 症候群(TDS ) 的症状之一。TM 作为阴囊的细菌房间肿瘤(TGCT ) 的一个增进知识的标记特别地有趣。工具包 ligand 基因( KITLG ), BCL2 对手/杀手 1 ( BAK1 ),并且表明对手 4 的 sprouty RTK ( SPRY4 ),基因与 TGCT 的高风险被联系骨头形态基因的蛋白质 7 基因( BMP7 ),转变生长因素贝它受体 3 基因( TGFBR3 ),并且 homeobox D 簇基因( HOXD )与 TDS 有关。使用的聚合酶链反应限制碎片长度多型性( PCR-RFLP )分析,我们为 KITLG 调查了等位基因和遗传型频率( rs995030 , rs1508595 ), SPRY4 ( rs4624820 , rs6897876 ), BAK1 ( rs210138 ), BMP7 ( rs388286 ), TGFBR3 ( rs12082710 ),并且在 142 个 TGCT 病人, 137 个 TM 病人,和 153 个肥沃的人(控制组)的 HOXD ( rs17198432 )。我们在 TM 在 KITLG GG_rs995030 遗传型发现了重要差别(P = 0.01 ) 并且 TGCT 病人(P = 0.0005 ) 与控制相比。我们也揭示了在 KITLG_rs1508595 和 TM 之间的强壮的协会(G 等位基因, P = 0.003;GG 遗传型, P = 0.01 ) 并且在 KITLG_rs1508595 和 TGCT 之间(G 等位基因, P = 0.0001;GG 遗传型, P = 0.0007 ) 。而且,在在 TGCT 组和控制之间的 BMP7_rs388286 有重要差别(T 等位基因, P = 0.00004;TT 遗传型, P = 0.00006 ) 并且在 TM 组和控制之间(T 等位基因, P = 0.04 ) 。HOXD 也与 TGCT 表明了一个强壮的协会(rs17198432 A 等位基因, P = 0.0001;AA 遗传型, P = 0.001 ) 。而且,重要差别在 BAK1_rs210138 G 等位基因在 TGCT 组和控制之间被发现(P = 0.03 ) 并且 GG 遗传型(P = 0.01 ) 。KITLG 和 BMP7 基因,与 TGCT 的发展联系了,可能也与 TM 有关。在摘要, KITLG GG_rs995030, GG_rs1508595, BMP7 TT_rs388286, HOXD AA_rs17198432,和 BAK1 GG_rs210138,遗传型与 TGCT 开发的高风险被联系。 | Ilya S Dantsev Evgeniy V Ivkin Aleksey A Tryakin Dmitriy N Godlevski Oleg Yu Latyshev Victoriya V Rudenko Dmitry S Mikhaylenko Vyacheslav B Chernykh Elena A Volodko Aleksey B Okulov Oleg B Loran Marina V Nemtsova | 2018 | Asian Journal of Andrology2018，20，6： | 4 |
| 2 | Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice显示文摘 | Collins Meredith A Bednar Filip Zhang Yaqing Brisset Jean-Christophe Galbán Stefanie Galbán Craig J Rakshit Sabita Flannagan Karen S Adsay N Volkan di Magliano Marina Pasca | 2012 | EN2012，，： | 3 |
| 3 | Effect of Calcineurin Inhibitors in the Outcome of Liver Transplantation in Hepatitis C Virus-Positive Recipients显示文摘 | Marina Berenguer Victoria Aguilera Fernando San Juan Salvador Benlloch Angel Rubin Rafael López-Andujar Angel Moya Eugenia Pareja Eva Montalva Maria Yago Manuel de Juan José Mir Martín Prieto | 2010 | Transplantation2010，，11： | 3 |
| 4 | Model acupuncture point:Bone marrow-derived stromal stem cells are moved by a weak electromagnetic field显示文摘AIM To show the existence of a structural formative role of magnetic fields(MFs) with respect to biological objects by using our proposed model of an acupoint.METHODS We introduced a magnetised 10-100 μT metal rod(needle) into culture dishes with a negatively charged working surface and observed during 24 h how cells were arranged by MFs and by electrical fields(EFs) when attached. Rat and human bone marrow-derived stromal stem cells(r BMSCs and h BMSCs), human nonadherent mononuclear blood cells, NCTCs and A172 cells, and Escherichia coli(E. coli) were evaluated. The dish containing BMSCs was defined as the model of an acupoint. r BMSCs proliferative activity affected by the needle was investigated. For investigating electromagnetic field structures, we used the gas discharge visualisation(GDV) method.RESULTS During 24 h of incubation in 50-mm culture dishes, BMSCs or the nonadherent cells accumulated into a central heap in each dish. BMSCs formed a torus(central ring) with an inner diameter of approximately10 mm only upon the introduction of the needle in the centre of the dish. The cells did not show these effects in 35- or 90-mm culture dishes or hydrophobic dishes or rectangular cuvettes. NCTCs and A172 cells showed unstable the effects and only up to two weeks after thawing. Moreover, we observed that the appearance of these effects depended on the season. In winter, BMSCs showed no the effects. GDV experiments revealed that the resonant annular illumination gradually formed from 10 to 18-20 s in polar solutions with and without cell suspension of BMSCs, NCTCs and E. coli when using circular 50-mm dishes, stimulation at 115 V and switching of the electrode poles at 1 kH z. All these data demonstrate the resonant nature of the central ring. Significant influence of MFs on the rB MSC proliferation rate was not observed.CONCLUSION BMSCs can be moved by MFs when in the presence of a constant EF and MF, when the cells are in the responsive functional state, and when there is a resonant relationship between them. | Artem N Emelyanov Marina V Borisova Vera V Kiryanova | 2016 | World Journal of Stem Cells2016，8，10： | 2 |
| 5 | Insulin resistance impairs sustained response rate to peginterferon plus ribavirin in chronic hepatitis C patients显示文摘 | Manuel Romero-Gómez Maria Del Mar Viloria Raúl J. Andrade Javier Salmerón Moisés Diago Conrado M. Fernández-Rodríguez Raquel Corpas Marina Cruz Lourdes Grande Luis Vázquez Paloma Mu?oz-de-Rueda Pilar López-Serrano Ana Gila María L. Gutiérrez Celia Pérez A | 2005 | Gastroenterology2005，，3： | 2 |
| 6 | Porcine circovirus type 2 (PCV2) Cap and Rep proteins are involved in the development of cell-mediated immunity upon PCV2 infection显示文摘 | Maria Fort Marina Sibila Miquel Nofrarías Eva Pérez-Martín Alex Olvera Enric Mateu Joaquim Segalés | 2010 | Veterinary Immunology and Immunopathology2010，，3： | 2 |
| 7 | 显示文摘 | Marina N Rumyantseva Alexander M | 2005 | Chemical Materials2005，17，： | 1 |
| 8 | Angiogenesis and yaseular targeting in Ewing sarcoma: a review of preclinical and clinical data显示文摘 | DUBOIS SG MARINA N GLADE- BENDER J | 2010 | Cancer2010，116，3： | 1 |
| 9 | Accuracy of Ultrasound Elastography in the Diagnosis of Thyroid Cancer in a Low-risk Population显示文摘 | A. Vidal-Casariego L. López-González A. Jiménez-Pérez M. Ballesteros-Pomar G. Kyriakos A. Urioste-Fondo R. álvarez-San Martín I. Cano-Rodríguez J. Jiménez-García de la Marina | 2012 | Exp Clin Endocrinol Diabetes2012，，10： | 1 |
| 10 | Biology and therapeutic advances for pediatric osteosarcoma显示文摘 | Marina N Gebhardt M Toet L | 2004 | Oncologist2004，9，4： | 1 |
| 11 | Astrocytes control breathing through pH - dependent release of A TP显示文摘 | Courine A V Kasymov V Marina N | 2010 | Science2010，329，5991： | 1 |
| 12 | Application of Magic-Angle Spinning NMR to Examine the Nature of Protons in Titanate Nanotubes显示文摘 | Bavykin Dmitry V Carravetta Marina Kulak Alexander N | 2010 | Chemistry of Materials2010，22，8： | 1 |
| 13 | Anti-inflammatory intestinal activity of Arctium lappa L. (Asteraceae) in TNBS colitis model显示文摘 | Ana Beatriz Albino de Almeida Marina Sánchez-Hidalgo Antonio Ramón Martín Anderson Luiz-Ferreira José Roberto Trigo Wagner Vilegas Lourdes Campaner dos Santos Alba Regina Monteiro Souza-Brito Catalina Alarcón de la Lastra | 2013 | Journal of Ethnopharmacology2013，，1： | 1 |
| 14 | Development of a high-performance liquid chromatography–electrospray ionization-quadrupole-time-of-flight-mass spectrometry methodology for the determination of three highly antihypertensive peptides in maize crops显示文摘 | Patrycja Puchalska M. Luisa Marina M. Concepción García | 2013 | Journal of Chromatography A2013，，： | 1 |
| 15 | Thermal,electrical,and electrocatalytical properties of lanthanum-doped strontium titanate显示文摘 | MARINA O A ANFIELD N L STVENSON J W | 2002 | Solid State Ionics2002，149，： | 1 |
| 16 | Ifosfamide plusetoposide in newly diagnosed Ewing's sarcoma of bone显示文摘 | Meyer WH Kun L Marina N | 1992 | J Clin Oncol1992，10，11： | 1 |
| 17 | Biology and therapeutic advances for pediatric osteosarcoma 显示文摘 | Marina N Gebhardt M Teot L | 2004 | Oncologist2004，9，： | 1 |
| 18 | Blood pressure-lowering properties of chokeberry显示文摘 | Jarkko K H Alexander N S Marina N M | 2010 | Journal of Functional Foods2010，，2： | 1 |
| 19 | Antioxidant activity of methanol extracts obtained from Plantago species 显示文摘 | MARINA G L CARMEN M N C PETER J H | 2005 | Journal of Agricultural and Food Chemistry2005，53，6： | 1 |
| 20 | Neuroprotective effects of intravitreal mesenchymal stem cell transplantation in experimental glaucoma显示文摘 | Johnson TV Bull ND Hunt DP Marina N Tomarev SI Martin KR | | 0，，04： | 1 |
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