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| 1 | Role of the microbiome in non-gastrointestinal cancers显示文摘'The forgotten organ',the human microbiome,comprises a community of microorganisms that colonizes various sites of the human body.Through coevolution of bacteria,archaea and fungi with the human host over thousands of years,a complex host-microbiome relationship emerged in which many functions,including metabolism and immune responses,became codependent.This coupling becomes evident when disruption in the microbiome composition,termed dysbiosis,is mirrored by the development of pathologies in the host.Among the most serious consequences of dysbiosis,is the development of cancer.As many as 20% of total cancers worldwide are caused by a microbial agent.To date,a vast majority of microbiomecancer studies focus solely on the microbiome of the large intestine and the development of gastrointestinal cancers.Here,we will review the available evidence implicating microbiome involvement in the development and progression of non-gastrointestinal cancers,while distinguishing between viral and bacterial drivers of cancer,as well as 'local' and 'systemic','cancer-stimulating' and 'cancer-suppressing' effects of the microbiome.Developing a system-wide approach to cancer-microbiome studies will be crucial in understanding how microbiome influences carcinogenesis,and may enable to employ microbiome-targeting approaches as part of cancer treatment. | Meirav Pevsner-Fischer Timur Tuganbaev Mariska Meijer Sheng-Hong Zhang Zhi-Rong Zeng Min-Hu Chen Eran Elinav | 2016 | World Journal of Clinical Oncology2016，7，2： | 5 |
| 2 | Diabetes,glycemic control,and new-onset heart failure in patients with stable coronary artery disease:data from the heart and soul study显示文摘 | Joost P van Melle Mariska Bot | 2010 | Diabetes Care2010，33，9： | 1 |
| 3 | Influence of Different Fat Emulsion-Based Intravenous Formulations on the Pharmacokinetics and Pharmacodynamics of Propofol显示文摘 | Eugene H. Cox Catherijne A. J. Knibbe Victorine S. Koster Mariska W. E. Langemeijer Erica E. Tukker Rogier Lange Paul F. M. Kuks Han J. M. Langemeijer Loraine Lie-A-Huen Meindert Danhof | 1998 | Pharmaceutical Research1998，，3： | 1 |
| 4 | L-Homoarginine and L-arginine are antagonistically related to blood pressure in an elderly population: the Hoorn study显示文摘 | Leonard P. van der Zwan Mariska Davids Peter G. Scheffer Jacqueline M. Dekker Coen D.A. Stehouwer Tom Teerlink | 2013 | Journal of Hypertension2013，，6： | 1 |
| 5 | A functional assay in yeast for the human estrogen receptor displays wild type and variant estrogen receptor messenger RNAs present in breast carcinoma显示文摘 | Mariska AJ Floore AN kim IM | 1997 | Cancer Res1997，57，： | 1 |
| 6 | Hepatic and intrahepatic targeting of an anti-inflammatory agent with human serum albumin and neoglycoproteins as carrier molecules显示文摘 | Eric J Robert W Mariska V | 1993 | Biochem Pharm1993，45，6： | 1 |
| 7 | Association of Coexisting Dia- betes and Depression With Mortality After Myocardial Infarction显示文摘 | Mariska B Francois P Marij Z | 2012 | Diabetes2012，35，3： | 1 |
| 8 | A functional assay in yeast for the human estrogen receptor displays wild-type and variant estrogen receptor messenger RNAs present in 'breast careinoma 显示文摘 | Mariska AJ Floore AN Kim IM | 1997 | Cancer Res1997，57，： | 1 |
| 9 | A hydrotalcite- based catalyst system for the single-stage liquid-phase synthesis of MIBK 显示文摘 | Ferry W Mariska W van Dillen A J | 2006 | Applied Catalysis A: General2006，307，： | 1 |
| 10 | 单个腺病毒颗粒的原子力显微镜液相成像及样品制备方法显示文摘原子力显微镜(Atomic force microscopy,AFM)作为一种纳米级高分辨率的探针扫描显微镜,在病毒形态学研究等领域有广泛的应用。为更好地利用AFM在接近病毒生理环境(液相)中观测单个病毒颗粒,选择合适的基底吸附病毒样品是重要的前提保障。本文介绍了一种病毒样品制备及AFM液相成像方法。首先制备疏水化处理的玻璃盖玻片作为吸附基底,再将观察样品腺病毒重组载体颗粒(Adenovirus type 5F35,Ad5F35)吸附于基底上,建立在液相下单个病毒颗粒的原子力显微镜成像方法。通过该方法获取了单个腺病毒颗粒在液相下的高分辨率纳米级高度图(height image),且病毒颗粒保持了约90nm的正确测量高度。实验结果表明疏水化处理的玻璃基底具有良好的吸附力,有助于病毒颗粒牢固地吸附在基底上,且不会引起较大的形变。本研究为AFM观测病毒等生物样品提供了一种较为合适的吸附基底和在液相中的AFM成像方法,对后期开展病毒形态结构、物理属性及其与宿主细胞受体相互作用的研究打下基础。 | 梁艳 李晨 Mariska G M van Rosmalen Gijs J L Wuite Wouter H Roos | 2015 | 病毒学报2015，31，6： | 1 |
| 11 | A functional assay in yeast for the human estrogen receptor desplays wild type and variant estrogen receptor messenger RNAs present in breast carcinona显示文摘 | Mariska A J Floore A N Kim I M | 1997 | Cancer Res1997，57，6： | 1 |
| 12 | The effect of increased branched-chain amino acid transaminase activity in yeast on the production of higher alcohols and on the flavour profiles of wine and distillates显示文摘 | LILLY MARISKA FLORIAN F | 2006 | FEMS Yeast Research2006，6，5： | 1 |
| 13 | Analysis of cytokine production by graft IFNiltring cell isolated from rejection renal allograft显示文摘 | BEINITO A Y MARISKA K MARION E P | 1994 | Transplantation1994，57，2： | 1 |
| 14 | Improved nitrogen removal by application of new nitrogen-cycle bacteria显示文摘 | Mike S.M. Jetten Markus Schmid Ingo Schmidt Mariska Wubben Udo van Dongen Wiebe Abma Olav Sliekers Niels Peter Revsbech Hubertus J.E. Beaumont Lars Ottosen Eveline Volcke H.J. Laanbroek Jose Luis Campos-Gomez Jeff Cole Mark van Loosdrecht Jan Willem Mulde | 2002 | Reviews in Environmental Science and Biotechnology2002，，1： | 1 |
| 15 | Struvite precipitation thermodynamics in source-separated urine显示文摘 | Mariska Ronteltap Max Maurer Gujer Willi | 2007 | Water Research2007，41，5： | 1 |
| 16 | How friendship network character- istics influence subjective well-being显示文摘 | MARISKA van der H HILDE C | 2012 | Soc Indicat Res2012，107，3： | 1 |
| 17 | Nerve growth factor stimulates in vitro invasive capacity of DU145 human prostatic cancer cells显示文摘 | Albert A. Geldof Mariska A. T. Kleijn B. Ramanath Rao W. W. Newling | 1997 | Journal of Cancer Research and Clinical Oncology1997，，2： | 1 |
| 18 | 672: Neonatal outcome following planned cesarean section of dichorial twins beyond 35 weeks of gestation: a 7-year retrospective analysis of a national registry显示文摘 | Ben Willem Mol Joris van der Post Simone Lunshof Mariska Noorlander Dimitri Papatsonis Freke Wilmink Chantal Hukkelhoven | 2011 | American Journal of Obstetrics and Gynecology2011，，1： | 1 |
| 19 | The behaviour ofphannaceuticals and heavy metals during stuvlte precipitation in urine显示文摘 | Max Maurer Willi Gujer | 2007 | Water Research2007，41，9： | 1 |
| 20 | Current insights in intra-abdominal hypertension and abdominal compartment syndrome: open the abdomen and keep it open.显示文摘 | Inneke E. laet Mariska Ravyts Wesley Vidts Jody Valk Jan J. Waele Manu L. N. G. Malbrain | 2008 | Langenbeck’s Archives of Surgery2008，，6： | 1 |
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