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| 1 | Extremely well-differentiated adenocarcinoma of the stomach: Clinicopathological and immunohistochemical features显示文摘瞄准:否则作为极其区分得好的腺癌(EWDA ) 知道,子宫的宫颈的最小的偏差癌被它的良性的显微镜的外观与它的好攻击的行为相对照描绘。以便阐明 clinicopathological 特征和 EWDA 的胃的对应物的生物行为,用免疫组织化学,我们为联系 oncogene 的产品的表型的表示,增生的活动,和表示分析了九损害。方法:包括外科手术前的活体检视诊断, Clinicopathological 特征被考察。用免疫组织化学,在胃的损害把 p53 和 c-erbB-2 蛋白质的索引和表示标记的 Ki-67 被检测。结果:在中间的地点或上面第三个胃和水虫息似的宏观的特征胃的 EWDA 是特征的。尽管 9 损害中的 4 个显示出仅仅焦点的淋巴或静脉的侵略,淋巴节点转移不是现在,任何一个都没损害死于病人(吝啬的后续时期, 56 瞬间) 。EWDA 的所有 9 个盒子能被分类进胃的显型(5 损害) 和肠的显型(4 损害) 。以前的类似于的胃的小凹的上皮,颈部粘液细胞或幽门的腺,而是他们的乳突的结构经常被伸长,肿瘤房间和他们的原子核稍微更大并且更亢奋与正常上皮相比色彩。后者与最小的原子非典型和不规则的腺类似于肠的组织变形;二这些损害表明了完全的肠的显型,当二表明了不完全的肠的显型时。把索引标记的 Ki-67 是低的,任何一个都没盒子揭示 p53 和 c-erbB-2 蛋白质的在表示上。结论:不同于宫颈的最小的偏差癌,这些调查结果建议胃的 EWDA 是低档恶意的损害。这有利生物行为被把索引和 p53 或 c-erbB-2 蛋白质在表示上的缺乏标记的低 Ki-67 的数据支持。因为它到有肠的组织变形的正常胃粘膜或粘膜的相似, EWDA 经常被误诊。阻止如此的损害的错误诊断,临床、病理学的特征应该被考虑。 | Takashi Yao Takashi Utsunomiya Masafumi Oya Kenichi Nishiyama Masazumi Tsuneyoshi | 2006 | World Journal of Gastroenterology2006，12，16： | 16 |
| 2 | DISSOLUTION THEORY OF GOLD IN ALKALINE THIOUREA SOLUTION(Ⅱ)——Electrochemical Study on Au-Fe Mix Anode in Alkaline Thiourea Solution Containing Na_2SO_3显示文摘1INTRODUCTIONManystudiesontheextractionofgoldfromoreorscrapwiththioureawerereported[1-3],butalthosewerelimitedonlyinacidicmed... | Chai Liyuan1 and Masazumi Okido2 1 Department of Nonferrous Metallurgy,Central South University of Technology, Changsha 410083, P. R. China2 Center for Integrated Research in Science and Engineering,Nagoya University, Nagoya 464, Japan | 1999 | 中国有色金属学会会刊:英文版1999，9，2： | 12 |
| 3 | DISSOLUTION THEORY OF GOLD IN ALKALINE THIOUREA SOLUTION(Ⅰ) Anodic Behavior on Gold in Alkaline Thiourea Solution Containing Na_2SO_3显示文摘INTRODUCTIONSincethioureawasutilizedasthelixiviantofgoldearlyin1932[1],extractinggoldfromoreorscrapbyacidicthioureasolutionha... | Chai Liyuan and Masazumi Okido Department of Nonferrous Metallurgy, Central South University of Technology, Changsha 410083, P. R.China Center for Integrated Research in Science and Engineering, Nagoya University, Nagoya 464, Japan | 1999 | 中国有色金属学会会刊:英文版1999，9，1： | 10 |
| 4 | Dissolution theory of gold in alkaline thiourea solution(Ⅲ) ——Thermodynamics on dissolution of gold in alkaline thiourea solution containing Na _2SO_3显示文摘The oxidants of gold were investigated in an alkaline thiourea solution containing Na 2CO 3, in which Na 2S 2O 8 is a proper oxidant for dissolving gold because of in such homogeneous sulfur system coexisting complex agent, oxidant and stabilizing agent. The thermodynamic analyses were conducted on the dissolving of gold in the alkaline thiourea solution containing Na 2SO 3 by the oxidants oxygen or Na 2S 2O 8. The results show that the possibility of gold dissolution reduces with increasing pH value, while oxygen acts as oxidant; and when Na 2S 2O 8 acts as the oxidant of gold in the alkaline thiourea solution of pH 12.5, decomposition potential of thiourea decreases from the standard value 0.42 V to -0.32 V, also the dissolution trend of gold enhances with shifting the mix potential of the solution to the positive direction. | Chai Liyuan(柴立元) 1, Masazumi Okido 2 1. Department of Nonferrous Metallurgy, Central South University of Technology, Changsha 410083, P.R.China 2. Center for Integrated Research of Science and Engineering, Nagoya University,Nagoya 464, Japan | 1999 | 中国有色金属学会会刊:英文版1999，9，3： | 9 |
| 5 | SELECTIVE DISSOLUTION OF GOLD IN AN ALKALINETHIOUREA SOLUTION BY ELECTROLYSIS显示文摘Anodic polarization behavior of gold, silver, copper, nickel and iron in potentiostatic condition has been examined in an alkaline aqueous thiourea solution, where gold is hardly dissoluble normally. The addition of Na2SO3 into the solution can accelerate anodic dissolution of gold. The factors affecting selective dissolution of gold in the alkaline thiourea solution by electrolysis have been studied, and the optimum condition was obtained. In 0.1 mol/L thiourea solution of pH 12. 5 containing 0. 5 mol/L Na2SO3 and 2. 5% acetone, at the potential of 0. 34 V vs NHE, at the temperature of 323 K, the dissolved mass of gold anode with the exposed area of 1. 0 cm2 reached more than 300 mg·dm-3 within 30 min, and other metals such as silver, copper, nickel and iron could hardly dissolve. | Zhang Chuanfu Chai Liyuan Zhong Haiyun (Department of Nonferrous Metallurgy, Central South University of Technology, Changsha 410083, China)Masazumi Okido RyouichiIchino(center erforIntegratedResearchinScienceandEngineering NagoyaUniversity,Nagoya464,Ja | 1997 | Journal of Central South University1997，9，2： | 8 |
| 6 | 通过水溶液还原法用抗坏血酸制备纳米铜颗粒(英文)显示文摘通过水溶液还原法用抗坏血酸还原Cu2+制备纳米铜颗粒,并研究溶液pH和Cu2O平均粒径对纳米铜颗粒制备的影响。在溶液pH值为3、5和7时,可制得铜颗粒,并且在pH=7时制得的铜颗粒粒径最小。在溶液pH为9和11时无法制得铜颗粒。Cu2O的平均粒径能影响铜粉的粒径。Cu2O的平均粒径越大,得到的铜颗粒越大。通过对反应过程中不同时间点收集的样品进行XRD分析,可探索出反应的进程。在反应过程中,Cu(OH)2首先作为前驱体出现,然后被还原为Cu2O,最后被还原为铜颗粒。 | 刘清明 Takehiro YASUNAMI Kensuke KURUDA Masazumi OKIDO | 2012 | Transactions of Nonferrous Metals Society of China2012，22，9： | 6 |
| 7 | Improvement of corrosion resistance of AZ31 Mg alloy by anodizing with co-precipitation of cerium oxide显示文摘Anodizing of AZ31 Mg alloy in NaOH solution by co-precipitation of cerium oxide was investigated.The chemical composition and phase structure of the coating film were determined via optical microscopy,SEM and XRD.The corrosion properties of the anodic film were characterized by using potentiodynamic polarization curves in 17 mmol/L NaCl and 0.1 mol/L Na2SO4 solution at 298 K.The corrosion resistance of AZ31 magnesium alloy is significantly improved by adding cerium oxide to alkaline solution.In addition,the surface properties are enhanced and the film contains no crack. | Salah Abdelghany SALMAN Ryo ichi ICHINO Masazumi OKIDO | 2009 | 中国有色金属学会会刊:英文版2009，19，4： | 6 |
| 8 | Na_2SO_3加速碱性硫脲溶液溶金的机理初探显示文摘Na2SO3可以改善硫脲在碱性介质中的稳定性;增大金在其中的阳极极化。Na2SO3参与金在碱性硫脲溶液中阳极溶解的反应级数大于1,表明Na2SO3可以加速金在碱性硫脲溶液中的溶解,其原因被认为是电化学还原和催化作用。 | 柴立元 Masazumi Okido | 2001 | 湖南有色金属2001，17，2： | 5 |
| 9 | SSJD14101300023292显示文摘 | Shinya Sugimoto Hidetaka Yamada Masazumi Takahashi Yuichi Morohoshi Naotaka Yamaguchi Yuya Tsunoda Hiroyuki Hayashi Haruhiko Sugimura Hirokazu Komatsu | 2014 | Gastric Cancer2014，，4： | 4 |
| 10 | Factors affecting the quality of life of patients after gastrectomy as assessed using the newly developed PGSAS-45 scale: A nationwide multi-institutional study显示文摘AIM To identify certain clinical factors other than the type of gastrectomy which affect the postoperative quality of life(QOL) of patients after gastrectomy.METHODS The postgastrectomy syndrome assessment scale(PGSAS)-45 was designed to assess the severity of symptoms, the living status and the QOL of gastrectomized patients. It consists of 45 items, of which 22 are original items while 23 were retrieved from the SF-8 and Gastrointestinal Symptoms Rating Scale questionnaires with permission. A nationwide surveillance study to validate PGSAS was conducted and 2368 gastric cancer patients who underwent various types of gastrectomy at 52 medical institutions were enrolled. Of these, 1777 patients who underwent total gastrectomy(TG) reconstructed with Roux-Y(n = 393), distal gastrectomy(DG) reconstructed with Billroth-I(n = 909), or DG reconstructed with Roux-Y(n = 475) were evaluated in the current study. The influence of the type of gastrectomy and other clinical factors such as age, sex, duration after surgery, the symptom severity, the degree of weight loss, dietary intake, and the ability for working on the postoperative QOL(i.e., dissatisfaction for daily life subscale, physical component summary and mental component summary of the SF-8) were examined by multiple regression analysis(MRA). In addition, importance of various symptoms such as esophageal reflux, abdominal pain, meal-related distress, indigestion, diarrhea, constipation and dumping on the postoperative living status and QOL were also appraised by MRA.RESULTS The postoperative QOL were significantly deteriorated in patients who underwent TG compared to those after DG. However, the extent of gastrectomy was not an influential factor on patients' QOL when adjusted by the MRA. Among various clinical factors, the symptom severity, ability for working, and necessity for additional meals were the most influential factorsto the postoperative QOL. As for the individual symptoms, meal-related distress, dumping, abdominal pain, and esophageal reflux significantly affected the postoperative QOL in that order, while the influence of indigestion, diarrhea and constipation was insignificant. CONCLUSION Several clinical factors such as the symptom severity(especially in meal-related distress and dumping), ability for working and necessity for additional meals were the main factors which affected the patients' wellbeing after gastrectomy. | Koji Nakada Masazumi Takahashi Masami Ikeda Shinichi Kinami Masashi Yoshida Yoshikazu Uenosono Yoshiyuki Kawashima Sayumi Nakao Atsushi Oshio Yoshimi Suzukamo Masanori Terashima Yasuhiro Kodera | 2016 | World Journal of Gastroenterology2016，22，40： | 4 |
| 11 | Quality of life after total vs distal gastrectomy with Rouxen-Y reconstruction: Use of the Postgastrectomy Syndrome Assessment Scale-45显示文摘AIM To investigate the detrimental impact of loss of reservoir capacity by comparing total gastrectomy(TGRY) and distal gastrectomy with the same Rouxen-Y(DGRY) reconstruction. The study was conducted using an integrated questionnaire, the Postgastrectomy Syndrome Assessment Scale(PGSAS)-45, recently developed by the Japan Postgastrectomy Syndrome Working Party.METHODS The PGSAS-45 comprises 8 items from the Short Form-8, 15 from the Gastrointestinal Symptom Rating Scale, and 22 newly selected items. Uni-and multivariate analysis was performed on 868 questionnaires completed by patients who underwent either TGRY(n = 393) or DGRY(n = 475) for stage I gastric cancer(52 institutions). Multivariate analysis weighed of six explanatory variables, including the type of gastrectomy(TGRY/DGRY), interval after surgery, age, gender, surgical approach(laparoscopic/open), and whether the celiac branch of the vagus nerve was preserved/divided on the quality of life(QOL).RESULTS The patients who underwent TGRY experienced the poorer QOL compared to DGRY in the 15 of 19 main outcome measures of PGSAS-45. Moreover, multiple regression analysis indicated that the type of gastrectomy, TGRY, most strongly and broadly impaired the postoperative QOL among six explanatory variables. CONCLUSION The results of the present study suggested that TGRY had a certain detrimental impact on the postoperative QOL, and the loss of reservoir capacity could be a major cause. | Masazumi Takahashi Masanori Terashima Hiroshi Kawahira Eishi Nagai Yoshikazu Uenosono Shinichi Kinami Yasuhiro Nagata Masashi Yoshida Keishiro Aoyagi Yasuhiro Kodera Koji Nakada | 2017 | World Journal of Gastroenterology2017，23，11： | 3 |
| 12 | Biological efficacy of perpendicular type-I collagen protruded from TiO_(2)-nanotubes显示文摘The aim of this study was to evaluate the biological efficacy of a unique perpendicular protrusion of type-I collagen(Col-I)from TiO2 nanotubes(NT-EPF surface).We hypothesized that the NT-EPF surface would play bifunctional roles in stimulating plateletmediated fibroblast recruitment and anchoring fibroblast-derived Col-I to form a perpendicular collagen assembly,mimicking the connective tissue attachment around natural teeth for the long-term maintenance of dental implants.Ti surface modification was accomplished in two steps.First,TiO2 nanotubes(NT)array was fabricated via anodization.Diameters and depths of NTs were controlled by applied voltage and duration.Subsequently,an electrophoretic fusion(EPF)method was applied to fuse Col-I into nanotube arrays in a perpendicular fashion.Surface wettability was assessed by contact angle measurement.The bioactivity of modified TiO2 surfaces was evaluated in terms of NIH3T3 fibroblast attachment,platelet activation,and collagen extension.Early attachment,aggregation,and activation of platelets as well as release of platelet-related growth factors were demonstrated on NTEPF surfaces.Platelet-mediated NIH3T3 cells migration toward NT-EPF was significantly increased and the attached cells showed a typical fibrous morphology with elongated spindle shape.A direct linkage between pseudopod-like processes of fibroblasts to NTEPF surfaces was observed.Furthermore,the engineered EPF collagen protrusion linked with cell-derived collagen in a perpendicular fashion.Within the limitation of this in vitro study,the TiO2 nanotube with perpendicular Col-I surface(NT-EPF)promoted better cell attachment,induced a strong platelet activation which suggested the ability to create a more robust soft tissue seal. | Chia-Yu Chen David M.Kim Cliff Lee John Da Silva Shigemi Nagai Toshiki Nojiri Masazumi Nagai | 2020 | International Journal of Oral Science2020，12，4： | 3 |
| 13 | Efficacy of direct-acting antiviral treatment for chronic hepatitis C: A single hospital experience显示文摘AIM To evaluate the efficacy of direct-acting antivirals(DAAs) in Kanto Rosai Hospital. METHODS All patients with hepatitis C virus(HCV) who underwent DAA prescription were enrolled in this study. The present study was a single center retrospective analysis using patients infected with HCV genotype 1 or 2. Resistance analysis was performed by using direct sequencing and cycleave PCR in genotype 1 patients treated with interferon(IFN)-free DAA. The primary endpoint was sustained virologic response at 12 wk after therapy(SVR12).RESULTS A total of 117 patients participated in the study, including 135 with genotype 1 and 42 with genotype 2. Of the 135 patients with genotype 1, 16 received protease inhibitor + IFN + ribavirin and all achieved SVR. Of the 119 patients who received IFN-free DAA(in different combinations), 102 achieved SVR and 9 failed(7/9 were on daclatasvir/asunaprevir and 2/9 on ledipasvir/sofosbuvir). Efficacy analysis was done only for 43 patients who received daclatasvir/asunaprevir. From this analysis, Y93 resistance-associated substitutions were significantly correlated with SVR.CONCLUSION The SVR rate was 98% for genotype 1 and 100% for genotype 2. However, caution is needed for HCV NS5 A resistance-associated substitutions that are selected by HCV NS5 A inhibitors because cerebrovascular adverse events are induced by some DAA drugs. | Rena Kaneko Natsuko Nakazaki Risa Omori Yuichiro Yano Masazumi Ogawa Yuzuru Sato | 2018 | World Journal of Hepatology2018，10，1： | 2 |
| 14 | Incidence and Prognostic Value of Early Repolarization Pattern in the 12-Lead Electrocardiogram显示文摘 | Daisuke Haruta Kiyotaka Matsuo Akira Tsuneto Shinichiro Ichimaru Ayumi Hida Nobuko Sera Misa Imaizumi Eiji Nakashima Koji Maemura Masazumi Akahoshi | 2011 | Circulation2011，，25： | 2 |
| 15 | Predictive factors for body weight loss and its impact on quality of life following gastrectomy显示文摘AIM To determine the predictive factors and impact of body weight loss on postgastrectomy quality of life(QOL). METHODS We applied the newly developed integrated questionnaire postgastrectomy syndrome assessment scale-45, which consists of 45 items including those from the Short Form-8 and Gastrointestinal Symptom Rating Scale instruments, in addition to 22 newly selected items. Between July 2009 and December 2010, completed questionnaires were received from 2520 patients with curative resection at 1 year or more after having undergone one of six types of gastrectomy for Stage Ⅰ gastric cancer at one of 52 participating institutions. Of those, we analyzed 1777 eligible questionnaires from patients who underwent total gastrectomy with Roux-en-Y procedure(TGRY) or distal gastrectomy with Billroth-I(DGBI) or Roux-en-Y(DGRY) procedures. RESULTS A total of 393, 475 and 909 patients underwent TGRY, DGRY, and DGBI, respectively. The mean age of patients was 62.1 ± 9.2 years. The mean time interval between surgery and retrieval of the questionnaires was 37.0 ± 26.8 mo. On multiple regression analysis, higher preoperative body mass index, total gastrectomy, and female sex, in that order, were independent predictors of greater body weight loss after gastrectomy. There was a significant difference in the degree of weight loss(P < 0.001) among groups stratified according to preoperative body mass index(< 18.5, 18.5-25 and > 25 kg/m2). Multiple linear regression analysis identified lower postoperative body mass index, rather than greater body weight loss postoperatively, as a certain factor for worse QOL(P < 0.0001) after gastrectomy, but the influence of both such factors on QOL was relatively small(R2, 0.028-0.080).CONCLUSION While it is certainly important to maintain adequate body weight after gastrectomy, the impact of body weight loss on QOL is unexpectedly small. | Kazuaki Tanabe Masazumi Takahashi Takashi Urushihara Yoichi Nakamura Makoto Yamada Sang-Woong Lee Shinnosuke Tanaka Akira Miki Masami Ikeda Koji Nakada | 2017 | World Journal of Gastroenterology2017，23，26： | 2 |
| 16 | Comparison of Surgical Results of D2 Versus D3 Gastrectomy (Para-Aortic Lymph Node Dissection) for Advanced Gastric Carcinoma: A Multi-Institutional Study显示文摘 | Chikara Kunisaki Hirotoshi Akiyama Masato Nomura Goro Matsuda Yuichi Otsuka Hidetaka Ono Yutaka Nagahori Hideo Hosoi Masazumi Takahashi Fumihiko Kito Hiroshi Shimada | 2006 | Annals of Surgical Oncology2006，，5： | 2 |
| 17 | Taming heterogeneous rhenium catalysis for the production of biomass-derived chemicals显示文摘Rhenium is one of important components for heterogeneous catalysts,which has been recently used for the catalytic reactions related to the production of biomass-derived chemicals such as deoxydehydration of vicinal OH groups,C-O hydrogenolysis,and hydrogenation of carboxylic acids,and so on.Suitable oxidation state of Re as a catalytic active species is strongly dependent on the catalytic reactions.The control of the oxidation state of Re species on the catalysts is crucial on the catalyst development. | Keiichi Tomishige Yoshinao Nakagawa Masazumi Tamura | 2020 | Chinese Chemical Letters2020，31，5： | 2 |
| 18 | Surface characteristics of chemical conversion coating for Mg-Al alloy显示文摘The chemical conversion coating was formed on Mg alloy for low cost and harmlessness in environment by using the colloidal silica as the main component.The film formed at 298 K was thick,which was thought to be the combination of Si and O.In salt spray test,the ratio of black rust on the specimen that did not conducted chemical conversion treatment was five times or more than those of the chemical conversion treated specimen.The film of chemical conversion coating produced by alkali treatment process was thinner than the specimen produced in basic chemical conversion treatment solution. | Masazumi OKIDO Ryoichi ICHINO Seong-Jong KIM Seok-Ki JANG | 2009 | 中国有色金属学会会刊:英文版2009，19，4： | 2 |
| 19 | Epithelial cell adhesion efficacy of a novel peptide identified by panning on a smooth titanium surface显示文摘Epithelial attachment via the basal lamina on the tooth surface provides an important structural defence mechanism against bacterial invasion in combating periodontal disease. However, when considering dental implants, strong epithelial attachment does not exist throughout the titanium-soft tissue interface, making soft tissues more susceptible to peri-implant disease. This study introduced a novel synthetic peptide(A10) to enhance epithelial attachment. A10 was identified from a bacterial peptide display library and synthesized. A10 and protease-activated receptor 4-activating peptide(PAR4-AP, positive control) were immobilized on commercially pure titanium. The peptide-treated titanium showed high epithelial cell migration ability during incubation in platelet-rich plasma. We confirmed the development of dense and expanded BL(stained by Ln5) with pericellular junctions(stained by ZO1) on the peptide-treated titanium surface. In an adhesion assay of epithelial cells on A10-treated titanium, PAR4-AP-treated titanium, bovine root and non-treated titanium, A10-treated titanium and PAR4-AP-treated titanium showed significantly stronger adhesion than non-treated titanium. PAR4-AP-treated titanium showed significantly higher inflammatory cytokine release than non-treated titanium. There was no significant difference in inflammatory cytokine release between A10-treated and non-treated titanium. These results indicated that A10 could induce the adhesion and migration of epithelial cells with low inflammatory cytokine release. This novel peptide has a potentially useful application that could improve clinical outcomes with titanium implants and abutments by reducing or preventing peri-implant disease. | Hidemichi Kihara David M.Kim Masazumi Nagai Toshiki Nojiri Shigemi Nagai Chia-Yu Chen Cliff Lee Wataru Hatakeyama Hisatomo Kondo John Da Silva | 2018 | International Journal of Oral Science2018，10，3： | 2 |
| 20 | Adult case of an omphalomesenteric cyst resected by laparoscopic-assisted surgery显示文摘这份报告由帮助 laparoscopic 的外科描述脐肠系膜包囊 resected 的一个极其稀罕的成年案例。A 29-years-old 日语人被提交并且因为一个腹的团和提高的浆液 CEA (carcinoembryonic 抗原) ,承认了到九州大学医院在 2001 年 8 月的水平(21.3 ng/mL ) 。腹的 CT 和美国与中隔和石灰化表明了一个膀胱的团。腹腔镜检查显示了一个大团被纳入他的腹壁,测量 110 公里 x 70 公里 x 50 公里并且充满了粘液。团是由帮助 laparoscopic 的外科的 resected。它的墙的组织检查所见显示出纤维肌性织物,脂肪组织,石灰化,和肠的结构。是脐肠系膜包囊最后被诊断。 | Fumi Sawada Rie Yoshimura Kenichi Ito Kazuhiko Nakamura Hajime Nawata Kazuhiro Mizumoto Shuji Shimizu Takahiro Inoue Takashi Yao Masazumi Tsuneyoshi Atushi Kondo Naohiko Harada | 2006 | World Journal of Gastroenterology2006，12，5： | 2 |
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