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| 1 | Management and prevention of acute and chronic lateral ankle instability in athletic patient populations显示文摘Acute and chronic lateral ankle instability are common in high-demand patient populations. If not managed appropriately, patients may experience recurrent instability, chronic pain, osteochondral lesions of the talus, premature osteoarthritis, and other significantlong-term disability. Certain populations, including young athletes, military personnel and those involved in frequent running, jumping, and cutting motions, are at increased risk. Proposed risk factors include prior ankle sprain, elevated body weight or body mass index, female gender, neuromuscular deficits, postural imbalance, foot/ankle malalignment, and exposure to at-risk athletic activity. Prompt, accurate diagnosis is crucial, and evidence-based, functional rehabilitation regimens have a proven track record in returning active patients to work and sport. When patients fail to improve with physical therapy and external bracing, multiple surgical techniques have been described with reliable results, including both anatomic and nonanatomic reconstructive methods. Anatomic repair of the lateral ligamentous complex remains the gold standard for recurrent ankle instability, and it effectively restores native ankle anatomy and joint kinematics while preserving physiologic ankle and subtalar motion. Further preventative measures may minimize the risk of ankle instability in athletic cohorts, including prophylactic bracing and combined neuromuscular and proprioceptive training programs. These interventions have demonstrated benefit in patients at heightened risk for lateral ankle sprain and allow active cohorts to return to full activity without adversely affecting athletic performance. | Brendan J Mc Criskin Kenneth L Cameron Justin D Orr Brian R Waterman | 2015 | World Journal of Orthopedics2015,6,2: | 20 |
| 2 | Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations显示文摘 | Thompson MC Fuller C Hogg TL Dalton J Finkelstein D Lau CC Chintagumpala M Adesina A Ashley DM KeUie SJ Taylor MD Curran T Gajjar A Gilbertson RJ | 2006 | 中国神经肿瘤杂志2006,4,1: | 17 |
| 3 | 螺内酯与可乐定作为难治性高血压第4种治疗药物的比较:难治性高血压的最佳治疗随机研究显示文摘该研究旨在通过一个多中心随机试验对作为难治性高血压患者的第4种治疗药物的螺内酯与可乐定进行比较。采用药丸计数评估药物治疗依从性。难治性高血压患者(定义为包括1种利尿剂在内的3种药物治疗12周,诊室及动态血压监测血压仍未控制)随机给予螺内酯(12.5~50 mg/d)或可乐定(0.1~0.3mg,2次/d)继续治疗12周。 | Krieger EM Drager LF Giorgi DMA Pereira AC Barreto-Filho JAS Nogueira AR Mill JG Lotufo PA Amodeo C Batista MC Bodanese LC Carvalho ACC Castro I Chaves H Costa EAS Feitosa GS Franco RJS Fuchs FD Guimarāes AC Jardim PC Machado CA Magalhāes ME Mion D Jr Nascimento RM Nobre F Nóbrega AC Ribeiro ALP Rodrigues-Sobrinho CR Sanjuliani AF Teixeira MDCB Krieger JE ReHOT Investigators 赵狄 练桂丽 | 2018 | 中华高血压杂志2018,26,3: | 7 |
| 4 | 妊娠期高血压疾病对远期心血管病的影响显示文摘对妇女妊娠期高血压疾病(hypertensive disorder of pregnancy,HDP)史的研究,可能有助于改善动脉粥样硬化性心血管病的风险评估。但是,有HDP既往史的中年无症状妇女在未来患心血管病的风险仍未知。该研究旨在探讨有或无HDP既往史的中年女性心血管病的远期发病率。纳入标准:在前瞻性、观察性英国生物资料库中,纳入40~69岁并至少有一活产的英国妇女,对其中一亚组妇女进行了无创性动脉硬度测量。 | 周卫(译) 叶鹏(摘、审校) Honigberg MC Zekavat SM Aragam K Klarin D Bhatt DL Scott NS Peloso GM Natarajan P | 2020 | 中华高血压杂志2020,28,2: | 6 |
| 5 | 改进永磁同步电机转矩控制精度的措施显示文摘各种各样的实际因素会导致永磁同步电机在求取转矩时很难绝对精确。比如转子温升会导致磁场强度降低并使得输出转矩减小。导致转矩减小的另一种情况是在过载时铁心出现饱和。针对这样的情况,现在比较行之有效的设计思路是使用一个快速叠加速度控制环或者使用转矩传感器。但是,像绞车和注塑成型机一类的设备需要很高的转矩精度,而使用转矩传感器有诸多缺陷。本文将介绍三种不同的改进静态转矩精度的策略。第一种策略是基于对转矩常数和磁阻转矩常数的离线辨识。这一思想在第二种策略中得以扩展,即通过转矩与转距电流之间的关系来识别电机特性。这种策略通过采用多项式方程进行计算来补偿原开环控制的不足。第三种策略是一种在线自适应转矩常数控制技术,它基于对电机电参数的观测和对转速的测量。试验结果证实了三种策略理论的有效性。 | 薛靖 Dr.Guido Stoeppler Dr.Franz Bauer Siemens AG A&D MC Erlangen Germany | 2008 | 电力电子2008,6,1: | 2 |
| 6 | Thermal stability of SiC fibers (Nicalon) 显示文摘 | MAH T HECHT N L CULLUM D E Mc | 1984 | J Mater Sci1984,19,4: | 2 |
| 7 | 神经生长因子增强小胶质细胞的神经保护作用显示文摘小胶质细胞是脑组织内的防御细胞,但在病理和生理条件下,调控小胶质细胞活化的因子并不十分清楚。本研究发现,神经生长因子(NGF)可以增强小胶质细胞的神经保护和抗炎功能。在体内和体外研究中都发现,小胶质细胞表达NGF受体。原代培养小胶质细胞,给予NGF处理,转录本分析结果显示,NGF对小胶质细胞的运动、吞噬和降解吞噬物的能力均产生影响。对功能的研究显示,NGF可增加小胶质细胞的膜运动能力和胞饮作用;在体研究显示,NGF可激活小胶质细胞释放向外整流电流,调节周围谷氨酸能神经元的神经传递。既往研究提示,小胶质细胞有清除脑内Aβ肽的功能,本研究观察了NGF对小胶质细胞吞噬能力的影响。结果显示,NGF可促进小胶质细胞通过Trk A途径清除Aβ,并加速其降解。此外,NGF还可减轻由Aβ导致的炎症激活。特异性激活小胶质细胞还可以减轻由Aβ导致的神经元树突损伤和长时程增强抑制。在对离体脑片的研究中,我们也发现NGF可以促进小胶质细胞吞噬Aβ。综上所述,本研究证实NGF可以促进小胶质细胞活化,活化的小胶质细胞通过抗炎作用减轻Aβ聚集,发挥神经保护作用。 | 唐颖馨 Rizzi C Tiberi A Giustizieri M Marrone MC Gobbo F Carucci NM Meli G Arisi I D'Onofrio M Marinelli S Capsoni S Cattaneo A | 2018 | 神经损伤与功能重建2018,13,2: | 2 |
| 8 | A prospective feasibility study of sub-millisievert abdominopelvic CT using iterative reconstruction in Crohn’s disease显示文摘 | Siobhan B O’Neill Patrick D Mc Laughlin Lee Crush Owen J O’Connor Sebastian R Mc Williams Orla Craig Anne Marie Mc Garrigle Fiona O’Neill Jackie Bye Max F. Ryan Fergus Shanahan Michael M Maher | 2013 | European Radiology2013,,: | 2 |
| 9 | Acetazolamide vasoreactivity in vascular dementia: a positron emission tomographic study显示文摘 | DeReuck J Decoo D Hasenbroekx MC | 1999 | Eur Neurol1999,41,1: | 2 |
| 10 | Trauma-induced alterations in macrophage function显示文摘 | Mc Carler M D Mack V E Daly T M | 1998 | Surgery1998,123,: | 2 |
| 11 | Complete genomes of two clinical Staphylococcus aureus strains:evidence for the rapid evolution of virulence and drug resistance显示文摘 | Holden MT Feil EJ Lindsay JA Peacock SJ Day NP Enright MC Foster TJ Moore CE Hurst L Atkin R Barron A Bason N Bentley SD Chillingworth C Chillingworth T Churcher C Clark L Corton C Cronin A Doggett J Dowd L Feltwell T Hance Z Harris B Hauser H Holroyd S Jagels K James KD Lennard N Line A Mayes R Moule S Mungall K Ormond D Quail MA Rabbinowitsch E Rutherford K Sanders M Sharp S Simmonds M Stevens K Whitehead S Barrell BG Spratt BG Parkhill J | 2004 | Proc Natl Acad Sci USA2004,101,26: | 1 |
| 12 | Cytokine IL-1 beta but not IL-1 alpha promoter polymorphism is associated with Alzheimer disease in a population from the Canary Islands,Spain显示文摘 | Déniz-Naranjo MC Muoz-Fernandez C Alemany-Rodríguez MJ | 2008 | Euro J Neurol2008,15,10: | 1 |
| 13 | Coordination and local-ization in spinal motor systems显示文摘 | Tvesch MC Saltiel P d'Avella A | 2002 | Brain Res Rev2002,40,1: | 1 |
| 14 | Histologic and immunohistochemical characterization of lens capsule plagues in dogs with cataracts显示文摘 | Colitz CMH Malarkey D Dykstra MJ McGahan MC Davidson MG | 2000 | Am J Vet Res2000,61,2: | 1 |
| 15 | Systematic review of the impact of beta blockers on mortality and hospital admission in heart failure 显示文摘 | Shibata MC Flather MD Wang D | 2001 | Eur J Heart Fail2001,3,3: | 1 |
| 16 | Effects of transforming growth factor-beta 1 on human adrenocoritical fasciculata-reticularis cell differentiated functions显示文摘 | Lebrethon MC Jaillard C Naville D | 1994 | J Clin Endocrinol Metab1994,79,4: | 1 |
| 17 | Selective up-regulation of functional CXCR4 expression in erythroid cells by HIV-1 Tat protein显示文摘 | Gibellini D Re MC Vitone F | 2003 | Clin Exp Immunol2003,131,3: | 1 |
| 18 | Plasma Nitric Oxide Metabolite Levels Increase during Successive Exercise Stress Testing-A Link to Delayed Ischemic Preconditioning显示文摘 | ZDRENGHEA D BO'DIZS GY OBER MC | 2003 | J Exp Clin Cardio2003,8,: | 1 |
| 19 | Drug metabolism enzymes of mussels as bioindicators of chemical pollution 显示文摘 | Sheehan D Mc Intosh J Power A | 1995 | Biochemical Society Transactions1995,23,41: | 1 |
| 20 | Acetazolamide vasoreactivity in vascular dementia:a positron emission tomographic study显示文摘 | DeReuck J Decoo D Hasenbroekx MC | 1999 | Eur Neurol1999,41,1: | 1 |