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| 1 | Achalasia: A review of clinical diagnosis, epidemiology,treatment and outcomes显示文摘Achalasia is a neurodegenerative motility disorder of the oesophagus resulting in deranged oesophageal peristalsis and loss of lower oesophageal sphincter function.Historically,annual achalasia incidence rates were believed to be low,approximately 0.5-1.2 per 100000.More recent reports suggest that annual incidence rates have risen to 1.6 per 100000 in some populations.The aetiology of achalasia is still unclear but is likely to be multi-factorial.Suggested causes include environmental or viral exposures resulting in inflammation of the oesophageal myenteric plexus,which elicits an autoimmune response.Risk of achalasia may be elevated in a sub-group of genetically susceptible people.Improvement in the diagnosis of achalasia,through the introduction of high resolution manometry with pressure topography plotting,has resulted in the development of a novel classification system for achalasia.This classification system can evaluate patient prognosis and predict responsiveness to treatment.There is currently much debate over whether pneumatic dilatation is a superior method compared to the Heller’s myotomy procedure in the treatment of achalasia.A recent com-parative study found equal efficacy,suggesting that patient preference and local expertise should guide the choice.Although achalasia is a relatively rare condition,it carries a risk of complications,including aspiration pneumonia and oesophageal cancer.The risk of both squamous cell carcinoma and adenocarcinoma of the oesophagus is believed to be significantly increased in patients with achalasia,however the absolute excess risk is small.Therefore,it is currently unknown whether a surveillance programme in achalasia patients would be effective or cost-effective. | Orla M O'Neill Brian T Johnston Helen G Coleman | 2013 | World Journal of Gastroenterology2013,19,35: | 26 |
| 2 | A prospective feasibility study of sub-millisievert abdominopelvic CT using iterative reconstruction in Crohn’s disease显示文摘 | Siobhan B O’Neill Patrick D Mc Laughlin Lee Crush Owen J O’Connor Sebastian R Mc Williams Orla Craig Anne Marie Mc Garrigle Fiona O’Neill Jackie Bye Max F. Ryan Fergus Shanahan Michael M Maher | 2013 | European Radiology2013,,: | 2 |
| 3 | Stroke subtype classification to mechanism-specific and undetermined categories by TOAST,ASCO,and Causative Classification System显示文摘 | Michael M Caroline AD Orla C | 2010 | Stroke2010,41,8: | 1 |
| 4 | A combination of NOx trapping materials and urea-SCR eatalysts for use in the removal of NOx from mobile diesel engines显示文摘 | James A Sullivan Orla Keane | 2007 | Applied Catalysis B: Environmental2007,70,6: | 1 |
| 5 | Alcohol-induced generation of lipid peroxidation products in humans显示文摘 | Ern rn a A Orla P Burke A | 1999 | J Clin Inv1999,104,: | 1 |
| 6 | Analysis of waveguide silica glasses using Raman microscopy显示文摘 | Robert E. Noons Robin Devonshire Terry V. Clapp Suresh M. Ojha Orla McCarthy | 2008 | Journal of Non-Crystalline Solids2008,,26: | 1 |
| 7 | Different strokes for different folks:Entrepreneurial narratives of emotion,cognition,and making sense of business failure显示文摘 | Byrne Orla and Shepherd Dean A | 2015 | Entrepreneurship Theory and Practice2015,39,2: | 1 |
| 8 | Conservative management of placenta accreta and unruptured interstitial cornual pregnancy using methotrexate显示文摘 | Savita Lalchandani Michael Geary Colm O’Herlihy Orla Sheil | 2002 | European Journal of Obstetrics and Gynecology2002,,1: | 1 |
| 9 | Female perpetrators of child sexual abuse: characteristics of the offender and victim显示文摘 | Ashling Bourke Sally Doherty Orla McBride Karen Morgan Hannah McGee | 2014 | Psychology, Crime & Law2014,,8: | 1 |
| 10 | How Scientists Commercialise New Knowledge via Entrepreneurship显示文摘 | Colm O' Gorman Orla Byrne Dipti Pandya | 2008 | Journal of Technology Transfer2008,,1: | 1 |
| 11 | Small intestinal bacterial overgrowth in nonalcoholic steatohepatitis: association with toll- like receptor 4 expression and plasma levels of interleukin 8 显示文摘 | Ahmed Abu Shanab Paul Scully Orla Crosbie | 2010 | Dig Dis Sci2010,3,: | 1 |
| 12 | Flesh colour dominates consumer preference for chicken显示文摘 | Orla B. Kennedy Barbara J. Stewart-Knox Peter C. Mitchell David I. Thurnham | 2005 | Appetite2005,,2: | 1 |
| 13 | The Effect of an Organizational Net- work for Patient Safety on Safety Event Repor- ting显示文摘 | Lianne Jeffs Chris Hayes Orla Smith | 2014 | The Effect of anOrganizational Network for Patient Safety on Safety Event Reporting2014,37,3: | 1 |
| 14 | A Prospective Trial of Low-Dose Abdominal Computerised Tomography (CT) With Iterative Reconstruction vs Conventional CT in Crohn’s Disease显示文摘 | Orla F. Craig Siobhan B. O’Neill Sum Leong Fiona O’Neill Owen J. O’Connor Michael M. Maher Fergus Shanahan | 2011 | Gastroenterology2011,,: | 1 |
| 15 | Factors associated with mobile phone ownership and potential use for rabies vaccination campaigns in southern Malawi显示文摘Background:Rabies is a fatal but preventable viral disease,which causes an estimated 59000 human deaths globally every year.The vast majority of human rabies cases are attributable to bites from infected domestic dogs and consequently control of rabies in the dog population through mass vaccination campaigns is considered the most effective method of eliminating the disease.Achieving the WHO target of 70%vaccination coverage has proven challenging in low-resource settings such as Sub Saharan Africa,and lack of public awareness about rabies vaccination campaigns is a major barrier to their success.In this study we surveyed communities in three districts in Southern Malawi to assess the extent of and socio-economic factors associated with mobile phone ownership and explore the attitudes of communities towards the use of short message service(SMS)to inform them of upcoming rabies vaccination clinics.Methods:This study was carried out between 1 October–3 December 2018 during the post-vaccination assessment of the annual dog rabies campaign in Blantyre,Zomba and Chiradzulu districts,Malawi.1882 questionnaires were administered to households in 90 vaccination zones.The surveys gathered data on mobile phone ownership and use,and barriers to mobile phone access.A multivariable regression model was used to understand factors related to mobile phone ownership.Results:Most survey respondents owned or had use of a mobile phone,however there was evidence of an inequality of access,with higher education level,living in Blantyre district and being male positively associated with mobile phone ownership.The principal barrier to mobile phone ownership was the cost of the phone itself.Basic feature phones were most common and few owned smartphones.SMS was commonly used and the main reason for not using SMS was illiteracy.Attitudes to receiving SMS reminders about future rabies vaccination campaigns were positive.Conclusions:The study showed a majority of those surveyed have the use of a mobile phone and most mobile phone owners indicated they would like to receive SMS messages about future rabies vaccination campaigns.This study provides insight into the feasibility of distributing information about rabies vaccination campaigns using mobile phones in Malawi. | Orla Marron Gareth Thomas Jordana LBurdon Bailey Dagmar Mayer Paul OGrossman Frederic Lohr Andy DGibson Luke Gamble Patrick Chikungwa Julius Chulu Ian GHandel Barend Mde C Bronsvoort Richard JMellanby Stella Mazeri | 2020 | Infectious Diseases of Poverty2020,9,3: | 1 |
| 16 | Mechanisms of obesity in- duced inflammation and insulin resistance: insights into the e- merging role of nutritional strategies 显示文摘 | Maeve A McAMle Orla M | 2013 | Front Endocrinol (Lausanne)2013,10,4: | 1 |
| 17 | Good practice in the management of amyotrophic lateral sclerosis: Clinical guidelines. An evidence‐based review with good practice points. EALSC Working Group显示文摘 | Peter Munch Andersen Gian Domenico Borasio Reinhard Dengler Orla Hardiman Katja Kollewe Peter Nigel Leigh Pierre‐Francois Pradat Vincenzo Silani Barbara Tomik | 2007 | Amyotrophic Lateral Sclerosis2007,,4: | 1 |
| 18 | System dynamics for humanitarian operations显示文摘 | Maria Besiou Orla Stapleton Luk N. Van Wassenhove | 2011 | Journal of Humanitarian Logistics and Supply Chain Management2011,,1: | 1 |
| 19 | The Oxfordshire Community Stroke Project classification: Correlation with imaging, associated complications, and prediction of outcome in acute ischemic stroke显示文摘 | Sean J. Pittock Dara Meldrum Orla Hardiman John Thornton Paul Brennan Joan T. Moroney | 2003 | Journal of Stroke and Cerebrovascular Diseases2003,,1: | 1 |
| 20 | Revealing Progesterone’s Role in Uterine and Mammary Gland Biology: Insights from the Mouse显示文摘 | Rodrigo Fernandez-Valdivia Atish Mukherjee Biserka Mulac-Jericevic Orla Conneely Francesco DeMayo Paula Amato John Lydon | 2005 | Semin Reprod Med2005,,01: | 1 |