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| 1 | Regression of cirrhosis during treatment with tenofovir disoproxil fumarate for chronic hepatitis B: a 5-year open-label follow-up study显示文摘 | Patrick Marcellin Edward Gane Maria Buti Nezam Afdhal William Sievert Ira M Jacobson Mary Kay Washington George Germanidis John F Flaherty Raul Aguilar Schall Jeffrey D Bornstein Kathryn M Kitrinos G Mani Subramanian John G McHutchison E Jenny Heathcote | 2012 | The Lancet2012，，： | 14 |
| 2 | Tumor necrosis factor-α-induced protein 1 and immunity to hepatitis B virus显示文摘AIM: To compare the gene expression profile in a pair of HBV-infected twins.METHODS: The gene expression profile was compared in a pair of HBV-infected twins.RESULTS: The twins displayed different disease outcomes. One acquired natural immunity against HBV,whereas the other became a chronic HBV carrier. Eightyeight and forty-six genes were found to be up- or downregulated in their PBMCs, respectively. Tumor necrosis factor-alpha-induced protein 1 (TNF-αIP1) that expressed at a higher level in the HBV-immune twins was identified and four pairs of siblings with HBV immunity by RTPCR. However, upon HBV core antigen stimulation,TNF-αIP1 was downregulated in PBMCs from subjects with immunity, whereas it was slightly upregulated in HBV carriers. Bioinformatics analysis revealed a K+channel tetramerization domain in TNF-αIP1 that shares a significant homology with some human, mouse, and C elegan proteins.CONCLUSION: TNF-αIP1 may play a role in the innate immunity against HBV. | Marie C Lin Nikki P Lee Ning Zheng Pai-Hao Yang Oscar G Wong Hsiang-Fu Kung Chee-Kin Hui John M Luk George Ka-Kit Lau | 2005 | World Journal of Gastroenterology2005，11，48： | 3 |
| 3 | Age at diagnosis of type 2 diabetes and cardiovascular risk factor profile:A pooled analysis显示文摘BACKGROUND The diagnosis of type 2 diabetes(T2D)in younger adults,an increasingly common public health issue,is associated with a higher risk of cardiovascular complications and mortality,which may be due to a more adverse cardiovascular risk profile in individuals diagnosed at a younger age.AIM To investigate the association between age at diagnosis and the cardiovascular risk profile in adults with T2D.METHODS A pooled dataset was used,comprised of data from five previous studies of adults with T2D,including 1409 participants of whom 196 were diagnosed with T2D under the age of 40 years.Anthropometric and blood biomarker measurements included body weight,body mass index(BMI),waist circumference,body fat percentage,glycaemic control(HbA1c),lipid profile and blood pressure.Univariable and multivariable linear regression models,adjusted for diabetes duration,sex,ethnicity and smoking status,were used to investigate the association between age at diagnosis and each cardiovascular risk factor.RESULTS A higher proportion of participants diagnosed with T2D under the age of 40 were female,current smokers and treated with glucose-lowering medications,compared to participants diagnosed later in life.Participants diagnosed with T2D under the age of 40 also had higher body weight,BMI,waist circumference and body fat percentage,in addition to a more adverse lipid profile,compared to participants diagnosed at an older age.Modelling results showed that each one year reduction in age at diagnosis was significantly associated with 0.67 kg higher body weight[95%confidence interval(CI):0.52-0.82 kg],0.18 kg/m^(2) higher BMI(95%CI:0.10-0.25)and 0.32 cm higher waist circumference(95%CI:0.14-0.49),after adjustment for duration of diabetes and other confounders.Younger age at diagnosis was also significantly associated with higher HbA1c,total cholesterol,low-density lipoprotein cholesterol and triglycerides.CONCLUSION The diagnosis of T2D earlier in life is associated with a worse cardiovascular risk factor profile,compared to those diagnosed later in life. | Mary M Barker Francesco Zaccardi Emer M Brady Gaurav S Gulsin Andrew P Hall Joseph Henson Zin ZinHtike Kamlesh Khunti Gerald P McCann Emma L Redman David R Webb Emma G Wilmot Tom Yates Jian Yeo Melanie J Davies Jack A Sargeant | 2022 | World Journal of Diabetes2022，13，3： | 2 |
| 4 | Severe Hand, Foot, and Mouth Disease Associated with Coxsackievirus A6 - Alabama, Connecticut, California, and Nevada, November 201 1 - February 2012显示文摘 | McIntyre Mary G Stevens Kelly M Davidson Sherri Pippin Tina Magill Dagny Kulhanjian Julie A Kelly Daniel Greenhow Tara L Salas Maria L Yagi Shigeo Padilla Tasha Berumen Ricardo Glaser Carol Landry Marie Louise Lott Jason Chen Lei Paulson | 2012 | EN2012，，12： | 2 |
| 5 | Comparison of some French-American hybrid wines with white Riesling using gas chromatography-olfactometry显示文摘 | CHISHOLM MARY G GUIHER L ElSE A VONAH THERESE M | 1994 | The American Journal of Enology and Viticulture1994，45，2： | 1 |
| 6 | Reactive oxygen species sources and biomolecular oxidative damage induced by aflatoxin B1and fumonisin B1 in rat spleen mononuclear cells显示文摘 | MARY V S THEUMER M G ARIAS S L | 2012 | Toxicology2012，，23： | 1 |
| 7 | Fetal anemia:new technologies显示文摘 | Segata M Mari G | 2004 | Curr Opin Obstel Gynecol2004，16，2： | 1 |
| 8 | The Effect of a Worksite Based Walking Program on Cardiovascular Risk in Previously Sedentary Civil Servants显示文摘 | Marie H M Elaine M M Colin A G B | 2006 | BM C Public Health2006，6，： | 1 |
| 9 | Metabolic syndrome and its components as predictors of incident type 2 diabetes mellitus in an Aboriginal community显示文摘 | Ley Sylvia H Harris Stewart B Mamakeesick Mary Noon Tina Fiddler Edith Gittelsohn Joel Wolever Thomas M S Connelly Philip W Hegele Robert A Zinman Bernard Hanley Anthony J G | 2009 | Canadian Medical Association. Journal2009，，6： | 1 |
| 10 | Science and technology for water purification in the coming decades显示文摘 | SHANNONL M A BOHN P W ELIMELECH M GEORGIADIS J G MARIAS B J MAYES A M | 2008 | Nature2008，452，3： | 1 |
| 11 | Personal authentica-tion using digital retinal images显示文摘 | Mario C Penedo M G Penas M | 2006 | Pattern Analysis and Ap-plications2006，9，1： | 1 |
| 12 | Melanoma metastasis suppression by chromosome 6:evidence for a pathway regulated by CRSP3and TXNIP显示文摘 | Mary E M Naohito H | 2003 | Cancer Res2003，63，2： | 1 |
| 13 | High organic carbon stock in a karstic soil of the Middle-European Forest Province persists after centuries-long agroforestry management显示文摘 | Yousif Abdel-Rahman Ahmed Viliam Pichler Marián Homolák Erika G?m?ryová Dezs? Nagy Magdaléna Pichlerová Juraj Gregor | 2012 | European Journal of Forest Research2012，，6： | 1 |
| 14 | Indentification of nosiheptide in feeds and detection of residues in animal tissues显示文摘 | Claude P Claude G Marie M | 1979 | J Asoc Off Anal Chem1979，62，5： | 1 |
| 15 | Middle cerebral artery peak sys- tolic velocity :a new Doppler parameter in the assessment of growth- restricted fetuses 显示文摘 | Mari G Hanif F Kruger M | 2007 | Ultrasound Obstet Gynecol2007，29，3： | 1 |
| 16 | Regression of cirrhosis during treatment with tenofovir disoproxil fumarate for chronic hepatitis B: a 5-year open-label follow-up study显示文摘 | Patrick Marcellin Edward Gane Maria Buti Nezam Afdhal William Sievert Ira M Jacobson Mary Kay Washington George Germanidis John F Flaherty Raul Aguilar Schall Jeffrey D Bornstein Kathryn M Kitrinos G Mani Subramanian John G McHutchison E Jenny Heathcote | 2012 | The Lancet2012，，： | 1 |
| 17 | Effectiveness of Trichoderma, Gliocladium and Paecilomyces in postharvest fruit protection 显示文摘 | Pratella G C Mari M | 1993 | Postharvest Biol and Teehnol1993，3，： | 1 |
| 18 | Prospective clinical ecalution ofelectronic portal imaging device 显示文摘 | Jef M M Mary V G Waller R B | 1996 | Int J Radiat Oncol Biol Phys1996，，34： | 1 |
| 19 | Developing applications for lactococcal bacteriocins 显示文摘 | PAUL ROSS R MARY G OLIVIA M | 1999 | Antonie Van Leeuwenhoek1999，76，1： | 1 |
| 20 | Middle cerebral artery peak systolic velocity:a new Doppler parameter in the assessment of growth-restricted fetuses显示文摘 | Mari G Hanif F Kruger M | 2007 | Ultrasound Obstet Gynecol2007，29，3： | 1 |
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