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| 1 | Microfluidic actuators based on temperature-responsive hydrogels显示文摘The concept of using stimuli-responsive hydrogels to actuate fluids in microfluidic devices is particularly attractive,but limitations,in terms of spatial resolution,speed,reliability and integration,have hindered its development during the past two decades.By patterning and grafting poly(N-isopropylacrylamide)PNIPAM hydrogel films on plane substrates with a 2μm horizontal resolution and closing the system afterward,we have succeeded in unblocking bottlenecks that thermo-sensitive hydrogel technology has been challenged with until now.In this paper,we demonstrate,for the first time with this technology,devices with up to 7800 actuated micro-cages that sequester and release solutes,along with valves actuated individually with closing and opening switching times of 0.6±0.1 and 0.25±0.15 s,respectively.Two applications of this technology are illustrated in the domain of single cell handling and the nuclear acid amplification test(NAAT)for the Human Synaptojanin 1 gene,which is suspected to be involved in several neurodegenerative diseases such as Parkinson’s disease.The performance of the temperature-responsive hydrogels we demonstrate here suggests that in association with their moderate costs,hydrogels may represent an alternative to the actuation or handling techniques currently used in microfluidics,that are,pressure actuated polydimethylsiloxane(PDMS)valves and droplets. | Loïc D'Eramo Benjamin Chollet Marie Leman Ekkachai Martwong Mengxing Li Hubert Geisler Jules Dupire Margaux Kerdraon Clémence Vergne Fabrice Monti Yvette Tran Patrick Tabeling | 2018 | Microsystems & Nanoengineering2018，4，1： | 3 |
| 2 | Induction of Apoptosis by Crambene Protects Mice against Acute Pancreatitis via Anti-Inflammatory Pathways显示文摘 | Yang Cao Sharmila Adhikari Marie Véronique Clément Matthew Wallig Madhav Bhatia | 2007 | The American Journal of Pathology2007，，5： | 1 |
| 3 | Noninvasive diagnosis by Doppler Ultrasonography of fetal anemia resulting from parvovirus infection显示文摘 | Cosmi E Mari G Delle CL | 2002 | Am J Obstet Gynecol2002，187，5： | 1 |
| 4 | China's Growing Role in World Trade: The Anatomy of China's Export Growth显示文摘 | Mary Amiti CL Freund | 2011 | Re-search Working Papers2011，，29： | 1 |
| 5 | Are infants with orofacial clefts at risk for insecure mother-child attachments显示文摘 | Maris CL Endriga MC Speltz ML | 2000 | Cleft Palate Craniofac J2000，37，3： | 1 |
| 6 | Soybean isoflavones improves cardio-vascular risk factor without affecting the reproductive system of peripubertal rhesus monkeys显示文摘 | Mary S Anthony TB Clarkson CL | 1999 | J Nutr1999，126，： | 1 |
| 7 | Polymeric micelles ± a new generation of colloidal drug carriers 显示文摘 | Marie C J Jean CL | 1999 | Eur J Pharm Bbiopharm1999，48，： | 1 |
| 8 | Genetic diversity of Plasmodium vivax isolates from Azerbaiian显示文摘 | Marie CL Michela M Alexandra C | 2004 | Malaria J2004，40，： | 1 |
| 9 | Comparison of photosensitized plasma membrane damage caused by singlet oxygen and free radical 显示文摘 | Kocherar IE Christopher RL Mary CL et aL | 1996 | Biochim Biophys Acta1996，1280，： | 1 |
| 10 | Soybean isoflavones improves cardiovascular risk factor without affecting the reproductive system of peripubertal rhesus monkeys显示文摘 | Mary S Anthony TB Clarkson CL | 1999 | J Nutr1999，126，： | 1 |
| 11 | Soybean isoflavones improves cardiovascular risk factor without affecting the reproductive system of peripubertal rhesus monkeys显示文摘 | Anthony TB Clarkson CL | 1996 | J Nutri1996，126，： | 1 |
| 12 | 自然与文学显示文摘文学始终反映人与自然的复杂关系。原始文化与早期文明将自然视为人类活动的重要一员;中国古典诗歌以其独特哲学实现了人与自然的相通;浪漫主义者则于作品中不断呼唤对自然的热爱。然而,殖民化与工业化却让自然扭曲为人类的造物。面对危机,文学作为时代的回声,展现出了自身的力量。无数伟大先驱以文学作品创造出人与自然紧密相连的黄金时代,而今时今日来自亚、非、拉丁美洲的全新一代又发出了与之呼应的回声。事实上,每一种声音都是一条不同的道路。只有这些声音并进,才能创造出和谐共存的新世界。 | Jean Marie Gustave Le Clézio 施雪莹 | 2016 | 扬州大学学报(人文社会科学版)2016，20，6： | 1 |
| 13 | Initial testing of the aurora kinase A inhibitor MLN8237 by the Pediatric Preclini-cal Testing Program (PPTP)显示文摘 | Maris JM Morton CL Gorlick R | | 0，，01： | 1 |
| 14 | caspase-8 mediates caspase-3 activation and cytochrome c release during singlet oxygen-induced apoptosis of hl-60 cells显示文摘 | Shou GZ Mary CL Irene EK | 1999 | Experimental Cell Research1999，250，1： | 1 |
| 15 | Updated spirometric reference values for adult Chinese in Hong Kong and implications on climcal utilization显示文摘 | MARY SI FANNY WK ARTHUR CL | 2006 | CHEST2006，129，2： | 1 |
| 16 | Soybean isoflavones improves cardiovascular risk factor without effecting the reproductive system of peripubertal rhesus monkeys 显示文摘 | Mary S Anthony TB Clarhson CL | 1996 | J Nutri1996，126，： | 1 |
| 17 | Clinical characteristics and surgical outcome of patients with temporal lobe tumors and epilepsy 显示文摘 | Jorge CL Nagahashi Marie SK Pedreira CC | 2000 | Arq Neuropsiquiatr2000，58，4： | 1 |
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