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| 1 | Perioperative pain control after total knee arthroplasty: An evidence based review of the role of peripheral nerve blocks显示文摘Over the last decades,the number of total knee arthroplasty procedures performed in the United States has been increasing dramatically.This very successful intervention,however,is associated with significant postoperative pain,and adequate postoperative analgesia is mandatory in order to allow for successful rehabilitation and recovery.The use of regional anesthesia and peripheral nerve blocks has facilitated and improved this goal.Many different approaches and techniques for peripheral nerve blockades,either landmark or,more recently,ultrasound guided have been described over the last decades.This includes but is not restricted to techniques discussed in this review.The introduction of ultrasound has improved many approaches to peripheral nerves either in success rate and/or time to block.Moreover,ultrasound has enhanced the safety of peripheral nerve blocks due to immediate needle visualization and as consequence needle guidance during the block.In contrast to patient controlled analgesia using opioids,patients with a regional anesthetic technique suffer from fewer adverse events and show higher patient satisfaction;this is important as hospital rank-ings and advertisement have become more common worldwide and many patients use these factors in order to choose a certain institution for a specific procedure.This review provides a short overview of currently used regional anesthetic and analgesic techniques focusing on related implications,considerations and outcomes. | Thomas Danninger Mathias Opperer Stavros G Memtsoudis | 2014 | World Journal of Orthopedics2014，5，3： | 20 |
| 2 | Perioperative outcomes and type of anesthesia in hip surgical patients: An evidence based review显示文摘Over the last decades the demand for hip surgery,be it elective or in a traumatic setting,has greatly increased and is projected to expand even further.Concurrent with demographic changes the affected population is burdened by an increase in average comorbidity and serious complications.It has been suggested that the choice of anesthesia not only affects the surgery setting but also the perioperative outcome as a whole.Therefore different approaches and anesthetic techniques have been developed to offer individual anesthetic and analgesic care to hip surgery patients.Recent studies on comparative effectiveness utilizing population based data have given us a novel insight on anesthetic practice and outcome,showing favorable results in the usage of regional vs general anesthesia.In this review we aim to give an overview of anesthetic techniques in use for hip surgery and their impact on perioperative outcome.While there still remains a scarcity of data investigating perioperative outcomes and anesthesia,most studies concur on a positive outcome in overall mortality,thromboembolic events,blood loss and transfusion requirements when comparing regional to gener-al anesthesia.Much of the currently available evidence suggests that a comprehensive medical approach with emphasis on regional anesthesia can prove beneficial to patients and the health care system. | Mathias Opperer Thomas Danninger Ottokar Stundner Stavros G Memtsoudis | 2014 | World Journal of Orthopedics2014，5，3： | 17 |
| 3 | Implant retention after acute and hematogenous periprosthetic hip and knee infections: Whom, when and how?显示文摘Periprosthetic joint infections(PJI) of the hip and the knee are grossly classified as early post-operative, acute hematogenous and late chronic infections. Whereas two-stage exchange arthroplasty is the standard of care in North America for treating chronic infections, irrigation and debridement(I and D) with retention of implants has been used in an attempt to treat the other two types of PJIs. The rationale of this approach is that a PJI may be eradicated without the need of explanting the prostheses, as long as it has not transitioned into a chronic state. With the present paper, we review current evidence regarding the role of I and D with implant retention for treating PJIs of the hip and the knee. While a very wide range of success rates is reported in different studies, a short period of time between initiation of symptoms and intervention seems to play a prominent role with regards to a successful outcome. Moreover, pathogens of higher virulence and resistance to antibiotics are associated with a poorer result. Specific comorbidities have been also correlated with a less favorable outcome. Finally, one should proceed with serial I and Ds only under the condition that a predefined,aggressive protocol is applied. In conclusion,when treating a PJI of the hip or the knee, all the above factors should be considered in order to decide whether the patient is likely to benefit from this approach. | Georgios K Triantafyllopoulos Vasileios Soranoglou Stavros G Memtsoudis Lazaros A Poultsides | 2016 | World Journal of Orthopedics2016，7，9： | 7 |
| 4 | Pulmonary complications after spine surgery显示文摘Spine surgery is one of the fastest growing branches of orthopedic surgery. Patients often present with a relatively high acuity and, depending on surgical approach, morbidity and mortality can be comparatively high. Among the most prevalent and most frequently fatalitybound perioperative complications are those affecting the pulmonary system; evidence of clinical or subclinical lung injury triggered by spine surgical procedures is emerging. Increasing burden of comorbidity among the patient population further increases the likelihood of adverse outcome. This review is intended to give an overview over some of the most important causes of pulmonary complications after spine surgery, their pathophysiology and possible ways to reduce harm associated with those conditions. We discuss factors surrounding surgical trauma, timing of surgery, bone marrow and debris embolization, transfusion associated lung injury, and ventilator associated lung injury. | Ottokar Stundner Fadi Taher Abhijit Pawar Stavros G Memtsoudis | 2012 | World Journal of Orthopedics2012，3，10： | 5 |
| 5 | Mortality of Patients With Respiratory Insufficiency and Adult Respiratory Distress Syndrome After Surgery:The Obesity Paradox显示文摘 | Memtsoudis SG Bombardieri AM Ma Y | 2012 | J Intensive Care Med2012，27，5： | 1 |
| 6 | A nationwide analysis of risk factors for in-hospital myocardial in- farction after total joint arthroplasty显示文摘 | MENENDEZ ME MEMTSOUDIS SG OPPERER M | 2015 | Int Orthop2015，39，4： | 1 |
| 7 | Epidemiology and risk factors for perioperative mortality after total hip and knee arthro- plasty显示文摘 | Memtsoudis S G Pumberger M Ma Y | 2012 | J Orthop Res2012，30，11： | 1 |
| 8 | Perioperative pain control af- ter total knee arthroplasty: An evidence based review of the role of pe- ripheral nerve blocks显示文摘 | Danninger T Opperer M Memtsoudis SG | 2011 | World J Orthop2011，129，6： | 1 |
| 9 | Additives to local anesthetics for peripheral nerve blocks or local anesthesia:a review of the literature显示文摘 | Opperer M Gerner P Memtsoudis SG | 2015 | Pain Manag2015，5，2： | 1 |
| 10 | Epidemiol- ogy and risk factors for perioperative mortality after total hip and knee arthroplasty显示文摘 | MEMTSOUDIS SG PUMBERGERM MAY | 2012 | J Orthop Res2012，30，11： | 1 |
| 11 | Bilateral total knee arthroplasty:risk factors for major morbidity and mortality 显示文摘 | MEMTSOUDIS SG MAY CHIU YL | 2011 | Anesth Analg2011，113，4： | 1 |
| 12 | Perioperative outcomes after unilateral and bilateral total knee arthroplasty显示文摘 | Memtsoudis SG Ma Y González Della Valle A | | 0，，06： | 1 |
| 13 | Inpatient falls after total knee arthroplasty:The role of anesthesia type and peripheral nerve blocks显示文摘 | Memtsoudis SG Danninger T Rasul R | 2014 | Anesthesiology2014，120，3： | 1 |
| 14 | Autonomic mechanisms in theage-related hypotensive effect of propofol显示文摘 | Memtsoudis S G The A H Heerdt P M | 2005 | Anesth Analg2005，100，： | 1 |
| 15 | Perioperative outcomes after unilateral and bilateral knee arthroplasty显示文摘 | Memtsoudis SG Ma Y Gonz6lez Della Valle A | 2009 | J Nesthesiology2009，111，： | 1 |
| 16 | Trends in mortality, complications, and demographics for primary hip arthroplasty in the United States显示文摘 | Spencer S. Liu Alejandro González Della Valle Melanie C. Besculides Licia K. Gaber Stavros G. Memtsoudis | 2009 | International Orthopaedics2009，，3： | 1 |
| 17 | The utility of urine desmosine as a marker of lung injury in spine surgery显示文摘 | Memtsoudis SG Starcher B Ma Y et a/ | 2010 | HSS J2010，6，2： | 1 |
| 18 | Autonomic mechanisms in the age- related hypotensive effect of propofol 显示文摘 | Memtsoudis SG The AH Heerdt PM | 2005 | Anesth Analg2005，100，1： | 1 |
| 19 | Inhospital complications and mortality of unilateral, bilateral,and revision TKA:based on an estimate of 4159661 diseharges显示文摘 | Memtsoudis S G Valle G D | 2008 | Clin Orthop Relat Res2008，466，： | 1 |
| 20 | Have bilateral total knee arthroplasties become safer? A population-based trend analysis显示文摘 | Memtsoudis SG Mantilla CB Parvizi J | 2013 | Clin Orthop Relat Res2013，471，1： | 1 |
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