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| 1 | Prognostic value of inflammation-based markers in patients with pancreatic cancer administered gemcitabine and erlotinib显示文摘AIM: To evaluate the value of systemic inflammationbased markers as prognostic factors for advanced pancreatic cancer(PC). METHODS: Data from 82 patients who underwent combination chemotherapy with gemcitabine and erlotinib for PC from 2011 to 2014 were collected retrospectively. Data that included the neutrophil-to-lymphocyte ratio(NLR), the platelet-to-lymphocyte ratio, and the C-reactive protein(CRP)-to-albumin(CRP/Alb) ratio were analyzed. Kaplan-Meier curves, and univariate and multivariate Cox proportional hazards regression analyses were used to identify the prognostic factors associated with progression-free survival(PFS) and overall survival(OS). RESULTS: The univariate analysis demonstrated the prognostic value of the NLR(P = 0.049) and the CRP/Alb ratio(P = 0.047) in relation to PFS, and a positiverelationship between an increase in inflammation-based markers and a poor prognosis in relation to OS. The multivariate analysis determined that an increased NLR(hazard ratio = 2.76, 95%CI: 1.33-5.75, P = 0.007) is an independent prognostic factor for poor OS. There was no association between the PLR and the patients' prognoses in those who had received chemotherapy that comprised gemcitabine and erlotinib in combination. The Kaplan-Meier method and the log-rank test determined significantly worse outcomes in relation to PFS and OS in patients with an NLR > 5 or a CRP/Alb ratio > 5.CONCLUSION: Systemic inflammation-based markers, including increases in the NLR and the CRP/Alb ratio, may be useful for predicting PC prognoses. | Jae Min Lee Hong Sik Lee Jong Jin Hyun Hyuk Soon Choi Eun Sun Kim Bora Keum Yeon Seok Seo Yoon Tae Jeen Hoon Jai Chun Soon Ho Um Chang Duck Kim | 2016 | World Journal of Gastrointestinal Oncology2016，8，7： | 12 |
| 2 | Dysphagia in patients with isolated pontine infarction显示文摘Little is known about dysphagia after pontine infarction. In this study, we evaluated the incidence of dysphagia after isolated pontine infarction and identified the predictive factors for the occurrence of dysphagia. A total of 146 patients were included in this study. All patients underwent clinical testing for dysphagia within 1 day after admission and at the time of discharge. We compared the incidence of dysphagia between patients with unilateral pontine infarction and those with bilateral pontine infarction. To evaluate the functional status of patients, we investigated their initial modified Rankin Scale(mRS) score and initial National Institutes of Health Stroke Scale(NIHSS) score within 1 day of admission. Of 146 patients, 50(34.2%) had dysphagia initially within 1 day after admission. At the second evaluation at the time of discharge, dysphagia was diagnosed in 24 patients(16.4%). Patients with bilateral pontine infarction were more likely to present with dysphagia. In addition, clinical severity(in terms of mRS and NIHSS scores) was identified as a predictor of dysphagia in patients with cerebral infarction(multiple binary logistic regression analysis, mRS: P = 0.011, NIHSS: P = 0.004). Dysphagia frequently occurs in patients with isolated pontine infarction. Clinicians should pay particular attention to the occurrence of dysphagia, especially in patients with bilateral pontine infarction or high functional disability. | Min Cheol Chang Sang Gyu Kwak Min Ho Chun | 2018 | Neural Regeneration Research2018，13，12： | 11 |
| 3 | Endoscopic submucosal tunnel dissection salvage technique for ulcerative early gastric cancer显示文摘Endoscopic submucosal dissection is an effective treatment modality for early gastric cancer(EGC), though the submucosal fibrosis found in ulcerative EGC is an obstacle for successful treatment. This report presents two cases of ulcerative EGC in two males, 73- and 80-year-old, with severe fibrosis. As endoscopic ultrasonography suggested that the EGCs had invaded the submucosal layer, the endoscopic submucosal tunnel dissection salvage technique was utilized for complete resection of the lesions. Although surgical gastrectomy was originally scheduled, the two patients had severe coronary heart disease, and surgeries were refused because of the risks associated with their heart conditions. The endoscopic submucosal tunnel dissection salvage technique procedures described in these cases were performed under conscious sedation, and were completed within 30 min. The complete en bloc resection of EGC using endoscopic submucosal tunnel dissection salvage technique was possible with a free resection margin, and no other complications were noted during the procedure. This is the first known report concerning the use of the endoscopic submucosal tunnel dissection salvage technique salvage technique for treatment of ulcerative EGC. We demonstrate that endoscopic submucosal tunnel dissection salvage technique it is a feasible method showing several advantages over endoscopic submucosal dissection for cases of EGC with fibrosis. | Hyuk Soon Choi Hoon Jai Chun Min Ho Seo Eun Sun Kim Bora Keum Yeon Seok Seo Yoon Tae Jeen Hong Sik Lee Soon Ho Um Chang Duck Kim Ho Sang Ryu | 2014 | World Journal of Gastroenterology2014，20，27： | 8 |
| 4 | Computed tomography findings for predicting severe acute hepatitis with prolonged cholestasis显示文摘AIM: To evaluate the significance of computed tomography (CT) findings in relation to liver chemistry and the clinical course of acute hepatitis. METHODS: Four hundred and twelve patients with acute hepatitis who underwent enhanced CT scanning were enrolled retrospectively. Imaging findings were analyzed for the following variables: gallbladder wall thickness (GWT), arterial heterogeneity, periportal tracking, number and maximum size of lymph nodes, presence of ascites, and size of spleen. The serum levels of alanine aminotransferase, alkaline phosphatase, bilirubin, albumin, and prothrombin time were measured on the day of admission and CT scan, and laboratory data were evaluated every 2-4 d for all subjects during hospitalization. RESULTS: The mean age of patients was 34.4 years, and the most common cause of hepatitis was hepatitis A virus (77.4%). The mean GWT was 5.2 mm. The number of patients who had findings of arterial heterogeneity, periportal tracking, lymph node enlargement > 7 mm, and ascites was 294 (80.1%), 348 (84.7%), 346 (84.5%), and 56 (13.6%), respectively. On multivariate logistic regression, male gender [odds ratio (OR) = 2.569, 95%CI: 1.477-4.469, P = 0.001], toxic hepatitis (OR = 3.531, 95%CI: 1.444-8.635, P = 0.006), level of albumin (OR = 2.154, 95%CI: 1.279-3.629, P = 0.004), and GWT (OR = 1.061, 95%CI: 1.015-1.110, P = 0.009) were independent predictive factors for severe hepatitis. The level of bilirubin (OR = 1.628, 95%CI: 1.331-1.991, P < 0.001) and GWT (OR = 1.172, 95%CI: 1.024-1.342,P = 0.021) were independent factors for prolonged cholestasis in multivariate analysis. CONCLUSION: In patients with acute hepatitis, GWT on CT scan was an independent predictor of severe hepatitis and prolonged cholestasis. | Sang Jung Park Jin Dong Kim Yeon Seok Seo Beom Jin Park Min Ju Kim Soon Ho Um Chang Ha Kim Hyung Joon Yim Soon Koo Baik Jin Yong Jung Bora Keum Yoon Tae Jeen Hong Sik Lee Hoon Jai Chun Chang Duck Kim Ho Sang Ryu | 2013 | World Journal of Gastroenterology2013，19，16： | 4 |
| 5 | Association Between Metabolic Syndrome and Helicobacter pylori Infection Diagnosed by Histologic Status and Serological Status显示文摘 | Dong Wook Shin Hyuk Tae Kwon Jung Min Kang Jin Ho Park Ho Chun Choi Min Seon Park Sang Min Park Ki Young Son BeLong Cho | 2012 | Journal of Clinical Gastroenterology2012，，10： | 3 |
| 6 | Effects of Hypnotics on Sleep Patterns and Functional Recovery of Patients with Subacute Stroke显示文摘 | Chung Reen Kim Min Ho Chun Eun Young Han | 2010 | American Journal of Physical Medicine & Rehabilitation2010，，4： | 2 |
| 7 | The Correlation of Endoscopic and Histological Diagnosis of Gastric Atrophy显示文摘 | Alisher Eshmuratov Jong Chun Nah Nayoung Kim Hye Seung Lee Hee Eun Lee Byoung Hwan Lee Min Sik Uhm Young Soo Park Dong Ho Lee Hyun Chae Jung In Sung Song | 2010 | Digestive Diseases and Sciences2010，，5： | 2 |
| 8 | Predictive value of glycosylated hemoglobin for mortality of patients with acute myocardial infarction undergoing percutaneous coronary intervention显示文摘 | Min Goo Lee Myung Ho Jeong Dong Han Kim Ki Hong Lee Keun Ho Park Doo Sun Sim Hyun Ju Yoon Nam Sik Yoon Kye Hun Kim Hyoung Wook Park Young Joon Hong Ju Han Kim Youngkeun Ahn Jeong Gwan Cho Jong Chun Park Jung Chaee Kang | 2012 | International Journal of Cardiology2012，，1： | 1 |
| 9 | Topical application of Pleurotus eryngii extracts inhibits 2,4-dinitrochlorobenzene-induced atopic dermatitis in NC/Nga mice by the regulation of Th1/Th2 balance显示文摘 | Jae Ho Choi Hyung Gyun Kim Sun Woo Jin Eun Hee Han Tilak Khanal Minh Truong Do Yong Pil Hwang Jun Min Choi Sung-Sik Chun Young Chul Chung Tae Cheon Jeong Hye Gwang Jeong | 2013 | Food and Chemical Toxicology2013，，： | 1 |
| 10 | A randomized, prospective trial on efficacy and tolerability of low-volume bowel preparation methods for colonoscopy显示文摘 | In Kyung Yoo Jong Soo Lee Hoon Jai Chun Yoon Tae Jeen Bora Keum Eun Sun Kim Hyuk Soon Choi Jae Min Lee Seung Han Kim Seung Joo Nam Hyo Sung Kang Hong Sik Lee Chang Duck Kim Soon Ho Um Yeon Seok Seo Ho Sang Ryu | 2014 | Digestive and Liver Disease2014，，： | 1 |
| 11 | Impact of Baseline Plaque Components on Plaque Progression in Nonintervened Coronary Segments in Patients With Angina Pectoris on Rosuvastatin 10 mg/day显示文摘 | Young Joon Hong Myung Ho Jeong Yun Ha Choi Eun Hye Ma Jum Suk Ko Min Goo Lee Keun Ho Park Doo Sun Sim Nam Sik Yoon Hyun Ju Youn Kye Hun Kim Hyung Wook Park Ju Han Kim Youngkeun Ahn Jeong Gwan Cho Jong Chun Park Jung Chaee Kang | 2010 | The American Journal of Cardiology2010，，9： | 1 |
| 12 | Different clinical outcomes of acute kidney injury according to acute kidney injury network criteria in patients between ST elevation and non-ST elevation myocardial infarction显示文摘 | Seung Hwan Hwang Myung Ho Jeong Khurshid Ahmed Min Chul Kim Kyung Hoon Cho Min Goo Lee Jum Suk Ko Keun Ho Park Doo Sun Sim Nam Sik Yoon Hyun Ju Yoon Kye Hun Kim Young Joon Hong Hyung Wook Park Ju Han Kim Young keun Ahn Jeong Gwan Cho Jong Chun Park Jung C | 2011 | International Journal of Cardiology2011，，1： | 1 |
| 13 | Plaque Characteristics in Culprit Lesions and Inflammatory Status in Diabetic Acute Coronary Syndrome Patients显示文摘 | Young Joon Hong Myung Ho Jeong Yun Ha Choi Jum Suk Ko Min Goo Lee Won Yu Kang Shin Eun Lee Soo Hyun Kim Keun Ho Park Doo Sun Sim Nam Sik Yoon Hyun Ju Yoon Kye Hun Kim Hyung Wook Park Ju Han Kim Youngkeun Ahn Jeong Gwan Cho Jong Chun Park Jung Chaee Kang | 2009 | JACC: Cardiovascular Imaging2009，，3： | 1 |
| 14 | Right lower limb apraxia in a patient with left supplementary motor area infarction: intactness of the corticospinal tract confirmed by transcranial magnetic stimulation显示文摘We reported a 50-year-old female patient with left supplementary motor area infarction who presented right lower limb apraxia and investigated the possible causes using transcranial magnetic stimulation. The patient was able to walk and climb stairs spontaneously without any assistance at 3 weeks after onset. However, she was unable to intentionally move her right lower limb although she understood what she supposed to do. The motor evoked potential evoked by transcranial magnetic stimulation from the right lower limb was within the normal range, indicating that the corticospinal tract innervating the right lower limb was uninjured. Thus, we thought that her motor dysfunction was not induced by motor weakness, and confirmed her symptoms as apraxia. In addition, these results also suggest that transcranial magnetic stimulation is helpful for diagnosing apraxia. | Min Cheol Chang Min Ho Chun | 2015 | Neural Regeneration Research2015，10，2： | 1 |
| 15 | Factors related to post‐operative metabolic acidosis following major abdominal surgery显示文摘 | Chi‐Min Park Ho‐Kyung Chun Kyeongman Jeon Gee Young Suh Dong Wook Choi Sung Kim | 2014 | 2014 (7-8)2014，，7： | 1 |
| 16 | Comparison of swallowing functions between brain tumor and stroke patients显示文摘 | Dae Hwan Park Min Ho Chun Sook Joung Lee etal | 2013 | Annals of rehabilitation medicine2013，37，5： | 1 |
| 17 | Searching for E-cadherin gene mutations in early onset diffuse gastric cancer and hereditary diffuse gastric cancer in Korean patients显示文摘 | Sollip Kim Jun-Won Chung Tae-Dong Jeong Young-Soo Park Jeong Hoon Lee Ji Yong Ahn Do Hoon Kim Kee Don Choi Woochang Lee Ho June Song Gin Hyug Lee Sail Chun Hwoon-Yong Jung Won-Ki Min Jin-Ho Kim | 2013 | Familial Cancer2013，，3： | 1 |
| 18 | The effect of polaprezinc on gastric mucosal protection in rats with ethanol-induced gastric mucosal damage: Comparison study with rebamipide显示文摘 | Hyuk Soon Choi Ji-Youn Lim Hoon Jai Chun Min Lee Eun Sun Kim Bora Keum Yeon Seok Seo Yoon-Tae Jeen Soon Ho Um Hong Sik Lee Chang Duck Kim Ho Sang Ryu Donggeun Sul | 2013 | 2013 (2-3)2013，，2： | 1 |
| 19 | Secondary parkinsonism induced by hydrocephalus after subarachnoid and intraventricular hemorrhage显示文摘Hydrocephalus can induce secondary parkinsonism(Shahar et al.,1988;Aggarwal et al.,1997;Racette et al.,2004).Physical factors such as increased ventricular pressure near the upper midbrain and basal ganglia are thought to cause mechanical disruption of dopaminergic systems(i.e.,the nigrostriatal pathways from the medial substantia nigra to the caudate nuclei and putamen and its frontal projection fibers from the basal ganglia) | Min Cheol Chang Min Ho Chun | 2016 | Neural Regeneration Research2016，11，8： | 1 |
| 20 | Predictors of no-reflow after percutaneous coronary intervention for culprit lesion with plaque rupture in infarct-related artery in patients with acute myocardial infarction显示文摘 | Young Joon Hong Myung Ho Jeong Yun Ha Choi Jum Suk Ko Min Goo Lee Won Yu Kang Shin Eun Lee Soo Hyun Kim Keun Ho Park Doo Sun Sim Nam Sik Yoon Hyun Ju Youn Kye Hun Kim Hyung Wook Park Ju Han Kim Youngkeun Ahn Jeong Gwan Cho Jong Chun Park Jung Chaee Kang | 2009 | Journal of Cardiology2009，，1： | 1 |
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