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| 1 | Ferroptosis is an autophagic cell death process显示文摘Ferroptosis 是调整坏死的一种铁依赖者形式。它在各种各样的人的疾病被含有,包括 ischemic 机关损坏和癌症。这里,我们报导 autophagy 的关键角色,特别地细胞的铁存储蛋白质(作为 ferritinophagy 知道的一个过程) 的 autophagic 降级,在 ferroptosis。用 RNAi,屏蔽结合了随后的基因分析,我们作为 ferroptosis 的积极管理者识别了多重 autophagy 相关的基因。Ferroptosis 正式就职导致了 autophagy 激活和 ferritin 和 ferritinophagy 货物受体 NCOA4 的作为结果的降级。一致地,由 autophagy 的阻塞的 ferritinophagy 的抑制或废除的 NCOA4 击倒联系 ferroptosis 的细胞的易变的铁的累积和反应的氧种类,以及最终的 ferroptotic 细胞死亡。因此, ferroptosis 是一个 autophagic 房间死亡过程,并且调停 NCOA4 的 ferritinophagy 由控制细胞的铁动态平衡支持 ferroptosis。 | Minghui Gao Prashant Monian Qiuhui Pan Wei Zhang Jenny Xiang Xuejun Jiang | 2016 | Cell Research2016，26，9： | 138 |
| 2 | MEKK1, MKK1/MKK2 and MPK4 function together in a mitogen-activated protein kinase cascade to regulate innate immunity in plants显示文摘激活 Mitogen 的蛋白质 kinase (MAPK ) 串联在调整植物起重要作用天生的有免疫力的回答。在到为有组成的防卫回答的异种的搜索的一幅基因屏幕,我们识别了展出房间死亡和组成的防卫回答的 mpk4 和 mekk1 的多重等位基因。双分子的荧光互补(BiFC ) 分析证明 MPK4 和 MEKK1 与 MKK1 和 MKK2 交往,二密切相关的 MAPK kinases。mkk1 和 mkk2 单身者异种植物没有明显的变异的显型。测试 MKK1 和 MKK2 是否冗余地工作, mkk1 mkk2 两倍异种被产生。mkk1 mkk2 两倍变异的植物在幼苗舞台和幼苗致命性显型死是温度依赖者。类似于 mpk4 和 mekk1 异种,两倍变异的幼苗积累的 mkk1 mkk2 H2O2 高级,显示自发的房间死亡,联系的组成地快速的致病(PR ) 基因和展览病原体抵抗。另外,由 flg22 的 MPK4 的激活在 mkk1 mkk2 被损害两倍异种,在地图 kinase 串联和 MPK4 和 MEKK1 建议那 MKK1 和 MKK2 功能否定地在植物调整天生的有免疫力的回答。 | Minghui Gao Jinman Liu Dongling Bi Zhibin Zhang Fang Cheng2, Sanfeng Chen Yuelin Zhang | 2008 | Cell Research2008，18，12： | 37 |
| 3 | Distribution of polycyclic aromatic hydrocarbons in sediments from Yellow River Estuary and Yangtze River Estuary,China显示文摘Surface sediment samples collected from twenty-one sites of Yellow River Estuary and Yangtze River Estuary were determined for sixteen priority polycyclic aromatic hydrocarbons (PAHs) by isotope dilution GC-MS method. The total PAH contents varied from 10.8 to 252 ng/g in Yellow River Estuary sediment, and from 84.6 to 620 ng/g in Yangtze River Estuary sediment. The mean total PAH content of Yangtze River Estuary was approximately twofold higher than that of Yellow River Estuary. The main reasons for the difference may be the rapid industrial development and high population along Yangtze River and high silt content of Yellow River Estuary. The evaluation of PAH sources suggested that PAHs in two estuaries sediments estuaries were derived primarily from combustion sources, but minor amounts of PAHs were derived from petroleum source in Yellow River Estuary. PAHs may be primary introduced to Yellow River Estuary via dry/wet deposition, wastewater effuents, and accidental oil spills, and Yangtze River Estuary is more prone to be affected by wastewater discharge. | HUI Yamei ZHENG Minghui LIU Zhengtao GAO Lirong | 2009 | Journal of Environmental Sciences2009，21，12： | 24 |
| 4 | Recent advances in optical dynamic metaholography显示文摘Holography,with the capability of recording and reconstructing wavefronts of light,has emerged as an ideal approach for future deep-immersive naked-eye display.However,the shortcomings(e.g.,small field of view,twin imaging,multiple or-ders of diffraction)of traditional dynamic holographic devices bring many challenges to their practical applications.Metasurfaces,planar artificial materials composed of subwavelength unit cells,have shown great potential in light field manipulation,which is useful for overcoming these drawbacks.Here,we review recent progress in the field of dynamic metasurface holography,from realization methods to design strategies,mainly including typical research works on dy-namic meta-holography based on tunable metasurfaces and multiplexed metasurfaces.Emerging applications of dynam-ic meta-holography have been found in 3D display,optical storage,optical encryption,and optical information pro-cessing,which may accelerate the development of light field manipulation and micro/nanofabrication with higher dimen-sions.A number of potential applications and possible development paths are also discussed at the end. | Hui Gao Xuhao Fan Wei Xiong Minghui Hong | 2021 | Opto-Electronic Advances2021，4，11： | 14 |
| 5 | Experimental study on the mechanical and failure behaviors of deep rock subjected to true triaxial stress:A review显示文摘It has become an inevitable trend of human development to seek resources from the deep underground.However,rock encountered in deep underground engineering is usually in an anisotropic stress state(σ_(1)>σ>σ_(3))due to the influences of geological structures and engineering disturbances.It is therefore essential to study the mechanical,seepage,and dynamic disaster behaviors of deep rock under true triaxial stress to ensure the safe operation of deep rock engineering and the efficient exploitation of deep resources.In recent years,experimental techniques and research on true triaxial rock mechanics have achieved fruitful results that have promoted the rapid development of deep rock mechanics;thus,it is necessary to systematically review and summarize these developments.This work first introduced several typical true triaxial testing apparatus and then reviewed the corresponding research progress on rock deformation,strength,failure mode,brittleness,and energy as well as the 3D volumetric fracturing(dynamic disaster)properties of deep rocks under true triaxial stress.Then,several commonly used true triaxial rock strength criteria and their applicability,the permeability characteristics and mathematical models of deep reservoir rocks,and the disaster-causing processes and mechanisms of disturbed volumetric fracturing(rockburst,compound dynamic disasters)in deep rock engineering were described.This work may provide an essential reference for addressing the true triaxial rock mechanics issues involved in deep rock engineering,especially regarding the stability of surrounding rock at depth,disaster prevention and control,and oil and gas exploitation. | Heping Xie Jun Lu Cunbao Li Minghui Li Mingzhong Gao | 2022 | International Journal of Mining Science and Technology2022，32，5： | 13 |
| 6 | Characteristics of air pollution by polychlorinated dibenzo-p-dioxins and dibenzofurans in the typical industrial areas of Tangshan City,China显示文摘The ambient air in vicinity of different industrial sources for PCDD/PCDFs was sampled by TSP/PM 10 active samplers and passive PUF disk samplers in Tangshan City,a metropolis containing clusters of various industrial plants.The ΣTEQ concentrations of ΣPCDD/ΣPCDFs ranged from 44.2 to 394.1 fg I-TEQ/m 3 with an average of 169.9 fg I-TEQ/m 3.2,3,4,7,8-PeCDF was the dominant contributor to TEQ,contributing 41% (12% to 55%),while 1,2,3,4,6,7,8-HpCDF,OCDD and OCDF were the major congeners for the total concentrations.The ratios of PCDF/PCDD reached 2.54 on average,suggesting that de novo synthesis in thermal processes played an important role to the airborne pollution of PCDD/PCDFs.The similarities congener profiles indicated that TSP and PM 10 active sampling methods are comparable for the determination of the PCDD/PCDFs in ambient air,and the ratios of concentrations determined by the two methods suggested that the PCDD/PCDFs tended to stay in fine particles.It was found that 2,3,7,8-TCDF and OCDD were the dominating congeners in the passive PUF disks samples.Through principal components analysis,the coke industry was suggested to be a relatively high potential emission source for PCDD/PCDFs in the ambient air of Tangshan,which was possibly formed by de novo synthesis mechanism.In this study,the atmospheric impacts to the environment from different industrial sources could be ranked as follows (from high to low):coking,iron sintering,steel making,power generation and chlorinate alkali chemical production industries. | Zhiyuan Ren Bing Zhang Pu Lu Cheng Li Lirong Gao Minghui Zheng | 2011 | Journal of Environmental Sciences2011，23，2： | 8 |
| 7 | Tailoring the mechanical anisotropy of sintered NdFeB magnets by Pr-Cu grain boundary reconstruction显示文摘Pr_(83)Cu_(17)(wt%) grain boundary reconstruction was applied to prepare sintered NdFeB magnets. The effects of addition amount and annealing on the bending strength were investigated. The results show that Pr_(83)Cu_(17) can not only effectively enhance the bending strength, but also change the mechanical anisotropy in two directions parallel and perpendicular to c-axis. The bending strength perpendicular to c-axis reaches 404 MPa in 10 wt% addition magnet, higher than 348 MPa along parallel direction. This change is attributed to the preferred distribution of boundary phases, i.e., ductile(Nd,Pr)-Fe-Cu phase along perpendicular direction to c-axis and(Nd,Pr)-Fe phase along parallel direction. Moreover, the Cu migration during 480 ℃ annealing is found to be related to this boundary phase distribution. | Minghui Tang Xiaoqian Bao Xuejiao Zhang Xing Mu Kechao Lu Jiheng Li Xuexu Gao | 2019 | Journal of Rare Earths2019，37，4： | 7 |
| 8 | Prevalence and treatment of hypertension in China: impacts of 2017 American College of Cardiology/American Heart Association High Blood Pressure Guideline显示文摘The definition, recommended treatment thresholds and targets of hypertension have been updated in the recent 2017 American College of Cardiology/American Heart Association(ACC/AHA) Guideline for the Prevention, Detection, Evaluation and Management of High Blood Pressure in Adults. However,the impacts of this guideline on Chinese population are currently unknown. In this study, we aim to provide updated data in China using criteria from the updated guideline. A multistage, stratified sampling method was used to obtain a representative sample of 50,171 adults aged 18 years and above.Hypertension was defined as an average systolic blood pressure !130 mm Hg, or an average diastolic blood pressure !80 mm Hg, or self-reported use of antihypertensive medications in past 2 weeks. The weighted prevalence of hypertension was 60.1%(95% confidence interval [CI] 59.3%–61.0%). The treatment rate and recommended treatment rate were 16.8%(95% CI 16.1%–17.6%) and 53.7%(95% CI52.6%–54.9%), respectively; the gap was more prominent among men and participants from rural areas.Hence, the adoption of the 2017 ACC/AHA guideline will lead to a substantial increase in both prevalence and number of patients needing treatment in China. The applicability of this guideline should be carefully evaluated based on evidence from Chinese population. | Chao Yang Jinwei Wang Bixia Gao Yan Zhang Fang Wang Luxia Zhang Minghui Zhao Yong Huo | 2018 | Science Bulletin2018，63，8： | 7 |
| 9 | Decomposition of hexachlorobenzene over Al_2O_3 supported metal oxidecatalysts显示文摘Decomposition of hexachlorobenzene(HCB)was investigated over several metal oxides(i.e.,MgO,CaO,BaO,La2O3,CeO2,MnO2, Fe2O3,and Co3O4)supported on Al2O3,which was achieved in closed system at a temperature of 300°C.Catalysts were prepared by incipient wetness impregnation with different metal oxides loading and impregnating solvents.The decomposition effciency of different catalysts for this reaction depends on the nature of the metal oxide used,and Al2O3 supported La2O3 was found to be the most active one.Pentachlorobenzene(PeCB),and all tetrachlorobenzene(TeCB),trichlorobenzene(TrCB),and dichlorobenzene(DCB)isomers were detected after the decomposition reaction,indicating that the decomposition was mainly a dechlorination process.The detection of all lower chlorinated benzenes suggested the complexity of decomposition and the presence of more than one dechlorination pathway. | Lifei ZHANG Minghui ZHENG Bing ZHANG Wenbin LIU Lirong GAO Te BA Zhiyuan REN Guijin SU | 2008 | Journal of Environmental Sciences2008，20，12： | 4 |
| 10 | High-performance solar-blind ultraviolet photodetector based on electrospun TiO2-ZnTiO3 heterojunction nano- wires显示文摘High-performance solar-blind UV (ultraviolet) photodetectors (PDs) based on low-dimension semiconducting nanostructures with high sensitivity, excellent cycle stability, and the ability to operate in harsh environments are critical for solar observations, space communication, UV astronomy, and missile tracking. In this study, TiO2-ZnTiO3 heterojunction nanowire-based PDs are successfully developed and used to detect solar-blind UV light. A photoconductive analysis indicates that the fabricated PDs are sensitive to UV illumination, with high sensitivity, good stability, and high reproducibility. Further analysis indicates that the rich existence of grain boundaries within the TiO2-ZnTiO3 nanowire can greatly decrease the dark current and recombination of the electron-hole pairs and thereby significantly increase the device's photosensitivity, spectra responsivity (1.1 ~ 106), and external quantum efficiency (4.3 ~ 108 %). Moreover, the PDs exhibit good photodetective performance with fast photoresponse and recovery and excellent thermal stability at temperatures as high as 175 ℃. According to these results, TiO2-ZnTiO3 heterojunction nanowires exhibit great potential for applications in high-performance optical electronics and PDs, particularly next-generation photodetectors with the ability to operate in harsh environments. | Haining Chong Guodong Wei Huilin Hou Huijun Yang Minghui Shang Fengmei Gao Weiyou Yang Guozhen Shen | 2015 | Nano Research2015，8，9： | 4 |
| 11 | Higher-dimensional chaotic dynamics of a composite laminated piezoelectric rectangular plate显示文摘The analysis on the chaotic dynamics of a six-dimensional nonlinear system which represents the averaged equation of a composite laminated piezoelectric rectangular plate is given for the first time. The theory of normal form and the energy-phase method are combined to investigate the higher-dimen-sional chaotic dynamics of the composite laminated piezoelectric rectangular plate. Firstly,the theory of normal form is used to reduce the six-dimensional averaged equation to the simpler normal form. Then,the energy-phase method is extended to analyze the global bifurcations and chaotic dynamics of a six-dimensional nonlinear system. The analysis results indicate that there exist the homoclinic bi-furcation and Shilnikov type multi-pulse chaos for the composite laminated piezoelectric rectangular plate. Finally,numerical simulations are also used to investigate the nonlinear dynamic characteristics of the composite laminated piezoelectric rectangular plate. The results of numerical simulations also demonstrate that there exist the chaotic motions and the multi-pulse jumping orbits of the composite laminated piezoelectric rectangular plate. | ZHANG Wei GAO MeiJuan YAO MingHui YAO ZhiGang | 2009 | Science China(Physics,Mechanics & Astronomy)2009，52，12： | 4 |
| 12 | Feasibility analysis of SO_2 absorption using a hydrophilic ceramic membrane contactor显示文摘Hydrophilic ceramic membranes would be potential candidates for membrane gas absorption if they could be applied to appropriate separation processes.This study highlights a novel concept for the practical implementation of SO_2 absorption in hydrophilic ceramic membrane that exhibits outstanding thermal and mechanical stabilities.With this aim,we investigated experimentally the performance of SO_2 absorption into aqueous sodium hydroxide (NaOH) solution in a hydrophilic alumina (Al_2O_3) membrane contactor in terms of SO_2 removal efficiency and SO_2 mass transfer flux,and compared the performance with that in a hydrophobic one.A series of experiments were performed at various conditions over a NaOH concentration range of 0–1.0 mol·L^(-1),a liquid flow rate range of 30–180 ml·min^(-1),a gas flow rate range of 120–1000 ml·min^(-1),an inlet SO_2 concentration range of 400–2000μl·L^(-1),and a temperature range of 10–35°C.It was found that the hydrophilic membrane was more competitive when using a NaOH concentration higher than 0.2 mol·L^(-1).Furthermore,it can be inferred that the hydrophilicα-Al_2O_3 membrane exhibited exceptional long-term stability under 480 h continuous operation. | Xingyin Gao Minghui Qiu Kaiyun Fu Peng Xu Xiangli Kong Xianfu Chen Yiqun Fan | 2018 | Chinese Journal of Chemical Engineering2018，26，10： | 4 |
| 13 | Chinese cohort study of chronic kidney disease: design and methods显示文摘 | Gao Bixia Zhang Luxia Wang Haiyan Zhao Minghui On behalf of the Chinese Cohort Study of Chronic KidneyDisease (C-STRIDE) | 2014 | Chinese Medical Journal2014，，11： | 4 |
| 14 | Evaporite minerals and geochemistry of the upper 400<ce:hsp sp='0.25'/>m sediments in a core from the Western Qaidam Basin, Tibet显示文摘 | Minghui Li Xiaomin Fang Chaolu Yi Shaopeng Gao Weilin Zhang Albert Galy | 2009 | Quaternary International2009，，1： | 2 |
| 15 | First principles study of CuAlO_2 doping with S显示文摘We study the electronic properties of CuAlO2 doped with S by the first principles calculations and find that the band gap of CuAlO2 is reduced after the doping.At the same time,the effective masses are also reduced and the density of states could cross the Fermi level.These results show that the conductivity of CuAlO2 could be enhanced by doping the impurities of S,which needs to be further studied. | GAO HaiGen 1,ZHOU Jian 1,2* & LU MingHui 1 1 National Laboratory of Solid State Microstructures and Department of Materials Science and Engineering,Nanjing University,Nanjing 210093,China 2 Group of Computational Condensed Matter Physics,National Laboratory of Solid State Microstructures and Department of Physics,Nanjing University,Nanjing 210093,China | 2010 | Science China(Physics,Mechanics & Astronomy)2010，53，7： | 2 |
| 16 | Distribution of DDT in a Typical DDT Waste Contaminated Site显示文摘 | Wenbin Liu Changliang Li Minghui Zheng Li Wang Sumei Li Te Ba Guijin Su Lirong Gao Lifei Zhang | 2008 | Bulletin of Environmental Contamination and Toxicology2008，，3： | 1 |
| 17 | Long-term persistence of polychlorinated dibenzo- p -dioxins and dibenzofurans in air, soil and sediment around an abandoned pentachlorophenol factory in China显示文摘 | Cheng Li Minghui Zheng Bing Zhang Lirong Gao Lidan Liu Xin Zhou Xiaodong Ma Ke Xiao | 2011 | Environmental Pollution2011，，： | 1 |
| 18 | Ferroelectricity in dopant-free HfO_(2) thin films prepared by pulsed laser deposition显示文摘As a high-k material,hafnium oxide(HfO_(2))has been used in gate dielectrics for decades.Since the discovery of polar phase in Si-doped HfO_(2) films,chemical doping has been widely demonstrated as an effective approach to stabilize the ferroelectric phase in HfO_(2) based thin films.However,the extra capping layer deposition,post-growth annealing and wake-up effect are usually required to arouse the ferroelectricity in HfO_(2) based thin films,resulting in the increase of complexity for sample synthesis and the impediment of device application.In this study,the ferroelectricity is observed in non-capped dopant-free HfO_(2) thin films prepared by pulsed laser deposition(PLD)without post-growth annealing.By adjusting the deposited temperature,oxygen pressure and thickness,the maximum polarization up to 14.7 m C/cm^(2) was obtained in 7.4 nm-thick film.The fraction of orthorhombic phase,concentrations of defects and size effects are considered as possible mechanisms for the influences of ferroelectric prop-erties.This study indicates that PLD is an effective technique to fabricate high-quality ferroelectric HfO_(2) thin films in the absence of chemical doping,capping layer deposition and post-growth annealing,which may boost the process of nonvolatile memory device application. | Yongjian Luo Zhenxun Tang Xiaozhe Yin Chao Chen Zhen Fan Minghui Qin Min Zeng Guofu Zhou Xingsen Gao Xubing Lu Jiyan Dai Deyang Chen Jun-Ming Liu | 2022 | Journal of Materiomics2022，8，2： | 1 |
| 19 | LKB1-AMPK axis negatively regulates ferroptosis by inhibiting fatty acid synthesis显示文摘Dear Editor,Ferroptosis has emerged as a new programmed cell death modality highly relevant to disease.1 Ferroptosis was initially discovered as an iron-dependent non-apoptotic cell death induced by a serial of ferroptosis-inducing agents(FIN),such as erastin and RSL3.Erastin activates ferroptosis by inhibiting the activity of system Xc−,a cystine-glutamate antiporter,resulting in the depletion of cellular cysteine and glutathione(GSH),thus breaking cellular redox homeostasis.Inactivation of glutathione peroxidase 4(GPX4),an enzyme required to remove the toxic lipid hydroperoxides can induce ferroptosis without the depletion of cellular cysteine and GSH. | Changzhi Li Xuan Dong Wenjing Du Xin Shi Kangjie Chen Wei Zhang Minghui Gao | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 1 |
| 20 | The prevalence and target antigens of Antithyroid drugs induced antineutrophil cytoplasmic antibodies (ANCA) in Chinese patients with hyperthyroidism显示文摘 | Gao Ying Zhao Minghui Guo Xiaohui | 2004 | Endocrine Research2004，30，2： | 1 |
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