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| 1 | The provincial pattern of the relationship between urbanization and economic development in China显示文摘在省的规模上理解在瓷器都市化和经济开发之间的关系具有深刻理论、实际的意义。在中国在全世界和 31 个省或自治区域从 124 个国家或区域基于数据,使用用象限地图途径的改进方法,这份报纸分析了在瓷器都市化和经济发展水平之间的关系的空间模式。学习识别了下列结果。(1 ) 31 个省级的区域掉进六个范畴:仅仅一个区域在锋利的在都市化上的范畴, 3 个区域在中等在都市化上, 11 细微在都市化上, 8 基本协作,一中等在都市化下面,和七细微在都市化下面。(2 ) 在在都市化和经济开发的水平之间的关系中的省的规模上有重要地区性的差别。(3 ) 都市化和经济开发的省的模式在东方和西方之间是显著地不同的。东方沿海的区域主要是过去城市化的,当中央、西方的区域主要是下面城市化的时。(4 ) 在都市化和经济开发的水平之间的关系类似于马修效果。因此,二重要卓见被建议。首先,在一些发达区域的在都市化上的现象应该用一些担心和警戒看。第二,都市化需要在中央、西方的区域中等被加快。 | CHEN Mingxing HUANG Yongbin TANG Zhipeng LU Dadao LIU Hui MA Li | 2014 | Journal of Geographical Sciences2014，24，1： | 50 |
| 2 | Regional applicability of seven meteorological drought indices in China显示文摘The definition of a drought index is the foundation of drought research.However,because of the complexity of drought,there is no a unified drought index appropriate for different drought types and objects at the same time.Therefore,it is crucial to determine the regional applicability of various drought indices.Using terrestrial water storage obtained from the Gravity Recovery And Climate Experiment,and the observed soil moisture and streamflow in China,we evaluated the regional applicability of seven meteorological drought indices:the Palmer Drought Severity Index(PDSI),modified PDSI(PDSI_CN) based on observations in China,self-calibrating PDSI(scPDSI),Surface Wetness Index(SWI),Standardized Precipitation Index(SPI),Standardized Precipitation Evapotranspiration Index(SPEI),and soil moisture simulations conducted using the community land model driven by observed atmospheric forcing(CLM3.5/ObsFC).The results showed that the scPDSI is most appropriate for China.However,it should be noted that the scPDSI reduces the value range slightly compared with the PDSI and PDSI_CN;thus,the classification of dry and wet conditions should be adjusted accordingly.Some problems might exist when using the PDSI and PDSI_CN in humid and arid areas because of the unsuitability of empiricalparameters.The SPI and SPEI are more appropriate for humid areas than arid and semiarid areas.This is because contributions of temperature variation to drought are neglected in the SPI,but overestimated in the SPEI,when potential evapotranspiration is estimated by the Thornthwaite method in these areas.Consequently,the SPI and SPEI tend to induce wetter and drier results,respectively.The CLM3.5/ObsFC is suitable for China before 2000,but not for arid and semiarid areas after 2000.Consistent with other drought indices,the SWI shows similar interannual and decadal change characteristics in detecting annual dry/wet variations.Although the long-term trends of drought areas in China detected by these seven drought indices during 1961-2013 are consistent,obvious differences exist among the values of drought areas,which might be attributable to the definitions of the drought indices in addition to climatic change. | YANG Qing LI MingXing ZHENG ZiYan MA ZhuGuo | 2017 | Science China Earth Sciences2017，60，4： | 21 |
| 3 | Mitochondrial transcription termination factor 2 binds to entire mitochondrial DNA and negatively regulates mitochondrial gene expression显示文摘(mTERF2 ) Mitochondrial 抄写结束因素 2 是绑在 mitochondrial DNA 的 mitochondrial 矩阵蛋白质。以前的研究证明了 mTERF2 的 overexpression 能禁止房间增长,但是机制到目前为止一直不是明确的。这研究试图在 vivo 介绍 mTERF2 的有约束力的模式给 mitochondrial DNA (mtDNA ) ,并且在 mtDNA, mRNA 抄写,和蛋白质翻译的复制上调查了 mTERF2 的生物功能。到全部 mtDNA 的 mTERF2 绑定经由染色质 immunoprecipitation 分析被识别。当 mTERF2 是在 HeLa 房间的 overexpressed 时,线粒体基因的 mtDNA 复制效率和表示层次显著地被禁止。mtDNA 内容的抑制水平是有 mRNA 和 mitochondrial 蛋白质表示的减少的层次的一样。总的来说, mTERF2 可能基于它 mtDNA 复制上的否定效果是一个细胞生长禁止者,它最后下面调整在是必要的为的线粒体的氧化 phosphorylation 部件,细胞是的所有精力新陈代谢。 | Weiwei Huang Min Yu Yang Jiao Jie Ma Mingxing Ma Zehua Wang Hong Wu Deyong Tan | 2011 | Acta Biochimica et Biophysica Sinica2011，43，6： | 17 |
| 4 | Modeling spatial and temporal variations in soil moisture in China显示文摘On the basis of station observations,an atmospheric field (ObsFC) was constructed for the Community Land Model version 3.5 (CLM3.5).The model (CLM3.5 driven with ObsFC,hereafter referred as to CLM3.5/ObsFC) was used to simulate soil moisture (SM) from 1951 to 2008 in China.The resulting SM was compared with in situ observations,remote-sensing data and estimations made by various land models,indicating that CLM3.5/ObsFC is capable of reproducing the temporospatial characteristics and long-term variation trends of SM over China.Using an in situ observation-based forcing field improves the simulation of SM.Analysis of SM simulated using CLM3.5/ObsFC shows that the overall spatial pattern of SM was characterized by a gradually decreasing and alternating distribution of arid-humid zones from the southeast to northwest.Regionally averaged SM was the driest over southern Xinjiang Province and western Inner Mongolia,while the most humid regions were located over the Northeast Plain,Jianghuai region and the Yangtze River basin.The long-term variation trends of SM were generally characterized by increases in arid and humid regions and decreases in semiarid regions.Moreover,the variation was relatively intense from the mid-1970s to the mid-1990s in the arid region.The time series was more stable in the humid region except for a period near 1970 and after the year 2003.A downward trend was most prominent in the semiarid region from the 1990s to the end of the time series.For 1951-2008,in the arid,semiarid and humid regions,the SM volume percentage changed by 2.35,-1.26 and 0.08,respectively.The variation trends and intensity remarkably differed among the different regions,with the most notable changes being over the arid and semiarid regions north of 35°N. | LI MingXing MA ZhuGuo NIU Guo-Yue | 2011 | Chinese Science Bulletin2011，56，17： | 17 |
| 5 | Soil moisture drought detection and multi-temporal variability across China显示文摘Soil moisture droughts can trigger abnormal changes of material and energy cycles in the soil-vegetation-atmosphere system,leading to important effects on local ecosystem,weather,and climate.Drought detection and understanding benefit disaster alleviation,as well as weather and climate predictions based on the understanding the land-atmosphere interactions.We thus simulated soil moisture using land surface model CLM3.5 driven with observed climate in China,and corrected wet bias in soil moisture simulations via introducing soil porosity parameter into soil water parameterization scheme.Then we defined soil moisture drought to quantify spatiotemporal variability of droughts.Over the period from 1951 to 2008,40%of months(to the sum of 12×58)underwent droughts,with the average area of 54.6%of total land area of China's Mainland.The annual monthly drought numbers presented a significant decrease in arid regions,but a significant increase in semi-arid and semi-humid regions,a decrease in humid regions but not significant.The Mainland as a whole experienced an increasing drought trend,with77.3%of areal ratio of decrease to increase.The monthly droughts in winter were the strongest but the weakest in summer,impacting 54.3%and 8.4%total area of the Mainland,respectively.The drought lasting three months or more occurred mainly in the semi-arid and semi-humid regions,with probability>51.7%,even>77.6%,whereas those lasting 6 and 12 months or more impacted mainly across arid and semi-arid regions. | LI MingXing MA ZhuGuo | 2015 | Science China Earth Sciences2015，58，10： | 13 |
| 6 | Soil moisture-based study of the variability of dry-wet climate and climate zones in China显示文摘An ensemble soil moisture dataset was produced from 11 of 25 global climate model (GCM) simulations for two climate scenarios spanning 1900 to 2099; this dataset was based on an evaluation of the spatial correlation of means and trends in reference to soil moisture simulations conducted using the community land model driven by observed atmospheric forcing. Using the ensemble soil moisture index, we analyzed the dry-wet climate variability and the dynamics of the climate zone boundaries in China over this 199-year period. The results showed that soil moisture increased in the typically arid regions, but with insignificant trends in the humid regions; furthermore, the soil moisture exhibited strong oscillations with significant drought trends in the transition zones between arid and humid regions. The dynamics of climate zone boundaries indicated that the expansion of semiarid regions and the contraction of semi-humid regions are typical characteristics of the dry-wet climate variability for two scenarios in China. During the 20th century, the total area of semiarid regions expanded by 11.5% north of 30°N in China, compared to the average area for 1970-1999, but that of semi-humid regions decreased by approximately 9.8% in comparison to the average for the period of 1970-1999, even though the transfer area of the humid to the semi-humid regions was taken into account. For the 21st century, the dynamics exhibit similar trends of climate boundaries, but with greater intensity. | LI MingXing MA ZhuGuo | 2013 | Chinese Science Bulletin2013，58，4： | 8 |
| 7 | Assessment of an Evapotranspiration Deficit Drought Index in Relation to Impacts on Ecosystems显示文摘Ecosystems have increasingly been subject to the challenge of heavy drought under global warming. To quantitatively evaluate the impacts of drought on ecosystems, it is necessary to develop a drought index that can sensitively depict the response of vegetation to drought evolution at a biological time scale. For the ability of direct connection between climate and ecosystem by deficit of evapotranspiration, in the present study, a drought index was defined based on standardized evapotranspiration deficit (SEDI), according to the difference between actual and potential evapotranspiration, to meet the need for highlighting drought impacts on ecological processes. Comparisons with traditional indices show that SEDI can reasonably detect droughts and climatic dry and wet transitions, especially at a monthly time scale, and can also regenerate long-term trends. Moreover, SEDI can more sensitively capture the biological changes of ecosystems in response to the dynamics of drought intensity, compared with the indices of precipitation and temperature. SEDI is more practical than the precipitation and temperature indices to highlight signals of biological effects in climate droughts. Hence, it has potential for use in assessments of climate change and its impact on ecosystems. | Xia ZHANG Mingxing LI Zhuguo MA Qing YANG Meixia LV Robin Clark | 2019 | Advances in Atmospheric Sciences2019，36，11： | 6 |
| 8 | Polymorphism-Dependent Dynamic Ultralong Organic Phosphorescence显示文摘Developing ultralong organic phosphorescence(UOP)materials with smart response to external stimuli is of great interest in photonics applications,whereas the manipulation of molecular stacking on tuning such dynamic UOP is still a formidable challenge.Herein,we have reported two polymorphs with distinct photoactivated dynamic UOP behavior based on a pyridine derivative for the first time.Our experiment revealed that the dynamic UOP behavior including photoactivation and deactivation feature is highly dependent on irradiation intensity and environmental atmosphere.Additionally,given the unique dynamic UOP feature,these phosphors have been successfully applied to phosphorescence-dependent molecular logic gate and timing data storage.This result not only paves a way to design smart functional materials but also expands the scope of the applications on organic phosphorescence materials. | Mingxing Gu Huifang Shi Kun Ling Anqi Lv Kaiwei Huang Manjeet Singh He Wang Long Gu Wei Yao Zhongfu An Huili Ma Wei Huang | 2020 | Research2020，，1： | 5 |
| 9 | Efficacy and safety of Reduqing granules in the treatment of common cold with wind-heat syndrome: a randomized, double-blind, double-dummy, positive-controlled trial显示文摘OBJECTIVE:To assess the efficacy and safety of Reduqing granules in patients with common cold with wind-heat syndrome(CCWHS).METHODS:A randomized, double-blind, double-dummy, parallel, positive-controlled trial included 72 CCWHS patients was performed.The participants were randomly assigned to two groups,Reduqing(RDQ) group and Lianhuaqingwen(LHQW) group, in a 1∶1 ratio.Patients in RDQ group received Reduqing granules and dummy Lianhuaqingwen capsules three times a day and patients in LHQW group received Lianhuaqingwen capsules and dummy Reduqing granules three times daily.The duration of treatment and follow-up were four days.RESULTS:There were no statistically significant differences in total markedly effective rate and total effective rate between RDQ group and LHQW group after treatment.Traditional Chinese Medicine(TCM) symptom score was significantly reduced after treatment in RDQ group, as well as in LHQW group.However, the difference of change in TCM symptom score between two groups was not statistically significant(P > 0.05).There were no significant differences between two groups in the median time to fever relief [RDQ group(4 ± 8) h vs LHQW group(4 ± 5) h] or the median time to fever clearance(RDQ group 47 h vs LHQW 36 h).No serious adverse events were reported during the study.CONCLUSION:Compared with Lianhuaqingwen capsules, Reduqing granules achieved similar therapeutic effect in the treatment of CCWHS and no drug-related adverse events were reported during the study.Therefore, Reduqing granules might be effective and safe in the treatment of CCWHS. | Ma Yanjiao Zhang Zhongyi Wei Lianbo He Shuai Deng Xun Ji Aimin Zhou Benjie Jiang Deqi Li Mingxing Wang Yong | 2017 | Journal of Traditional Chinese Medicine2017，37，2： | 5 |
| 10 | Regulation of the cell cycle via mitochondrial gene expression and energy metabolism in HeLa cells显示文摘人的颈的癌症 HeLa 房间有功能的线粒体。最近的研究建议了那 mitochondrial 新陈代谢在肿瘤房间增长起一个必要作用。不过,房间怎么协调 mitochondrial 动力学和房间周期前进,尚待被澄清。为了调查在函数和房间周期规定, mitochondrial 基因表达式侧面和细胞的 ATP 层次是的 mitochondrial 之间的关系,在现在的学习由房间周期进步分析决定了。HeLa 房间被浆液饥饿在 G0/G1 阶段同步,并且由恢复浆液文化重入房间周期,时间功课实验被执行分析 mitochondrial 抄写管理者的表示, mitochondrial 基因, mitochondrial 膜潜力(MMP ) ,细胞的 ATP 层次,和房间骑车前进。结果证明当逮捕 G0/G1 房间在包含浆液的媒介被刺激时, DNA 和表示的数量在开始在 2 h 时间点增加的线粒体 mRNA 和蛋白质铺平,而 MMP 和 ATP 水平在 4 点提高了 h。而且,在浆液触发了房间周期以后, cyclin D1 表示开始在 4 h 增加。ATP 合成 inhibitoroligomycintreatment 压制了 cyclin D1 和 cyclin B1 表示层次并且堵住了房间周期前进。一起拿,我们的结果建议增加的 mitochondrial 基因表示层次,氧化 phosphorylation 激活,和细胞的 ATP 满足增加是为被触发的重要事件房间周期。最后,我们证明 mitochondrial 基因表示层次和细胞的 ATP 内容紧在调整房间增长被调整并且可能玩一个中央角色。 | Wei Xiong Yang Jiao Weiwei Huang Mingxing Ma Min Yu Qinghua Cui Deyong Tan | 2012 | Acta Biochimica et Biophysica Sinica2012，44，4： | 5 |
| 11 | A confinement strategy to in-situ prepare a peanut-like N-doped, C-wrapped TiO_(2) electrode with an enhanced desalination capacity and rate for capacitive deionization显示文摘Capacitive deionization(CDI)technology has been considered a promising desalination technique,especially for brackish water,because of its relatively low energy consumption,facile operation,and easy regeneration of electrodes.However,the desalination capacity,cost,fabrication method,electrochemical stability,and environmental unfriendliness of the electrodes have restricted the practical application of the CDI technique.Herein,we reported the one-step in situ preparation of nitrogen-doped and carbon-decorated MXene-derived TiO_(2)(termed N-TiO_(2−x)/C)through the confinement-growth strategy.The small particle size(∼25 nm)and uniform distribution of a peanut-like N-TiO_(2−x)/C material could be ascribed to the confined growth space created by the nanoporous structure of melamine foam.The defects produced by N doping provide an enhanced electrical conductivity and more adsorption sites,while wrapping with a carbon shell layer increases the conductivity and offers protection for N-TiO_(2−x) to achieve an excellent electrochemical stability.The prepared N-TiO_(2−x)/C electrode is hydrophilic due to the abundant oxygen-containing functional groups(e.g.,C-O,N-Ti-O,-NO_(x),and-OH)and exhibits a high salt removal capacity(33.4 mg·g^(−1)),desalination rate(1.5 mg·g^(−1)·min^(−1)),and remarkable cycling stability(without declining after 100 cycles),which might be ascribed to the synergistic effects of the short ion diffusion path,more active adsorption sites,enhanced conductivity,pseudocapacitive behavior,and protection of the carbon shell layer.This work provides a confined-growth strategy to develop MXene-derived oxide electrodes for electrochemical desalination. | Mingxing Liang Xueting Bai Fei Yu Jie Ma | 2021 | Nano Research2021，14，3： | 5 |
| 12 | Has the stilling of the surface wind speed ended in China?显示文摘Since the 1960 s,the global land surface wind speed(SWS)has significantly weakened,a phenomenon known as global terrestrial stilling.The latest research found that the stilling reversed around 2010,and since then the global SWS has been strengthening.However,there is still a lack of systematic quantitative analysis in China.We analyzed the transition and regional differences in the long-term trends of the SWS in China based on observational SWS data from 1971 to 2019.The results showed that annual mean SWS in China underwent a reversal from a continuously weakening trend to a significantly strengthening trend around 2014 and implying that stilling may have ended in 2014.The reversal had obvious regional and seasonal variations.In Northeast China,Western Xinjiang as well as on the Tibetan Plateau,the years with both annual and seasonal mean SWS changing from weakening to strengthening were around 2013/2014,1993/1994,and 2000.However,in the west of North China,SWS showed an obviously strengthening trend only in autumn and winter after 2007;while only autumn mean SWS showed a strengthening trend after 2012 in South China.It should be noted that stilling is ongoing in the eastern and southern coastal areas,North China and Eastern Xinjiang. | Qing YANG Mingxing LI Ziqing ZU Zhuguo MA | 2021 | Science China Earth Sciences2021，64，7： | 4 |
| 13 | Identifying EGFR-Expressed Cells and Detecting EGFR Multi-Mutations at Single-Cell Level by Microfluidic Chip显示文摘EGFR mutations companion diagnostics have been proved to be crucial for the efficacy of tyrosine kinase inhibitor targeted cancer therapies. To uncover multiple mutations occurred in minority of EGFR-mutated cells,which may be covered by the noises from majority of unmutated cells, is currently becoming an urgent clinical requirement. Here we present the validation of a microfluidic-chip-based method for detecting EGFR multimutations at single-cell level. By trapping and immunofluorescently imaging single cells in specifically designed silicon microwells, the EGFR-expressed cellswere easily identified. By in situ lysing single cells, the cell lysates of EGFR-expressed cells were retrieved without cross-contamination. Benefited from excluding the noise from cells without EGFR expression, the simple and cost-effective Sanger's sequencing, but not the expensive deep sequencing of the whole cell population, was used to discover multi-mutations. We verified the new method with precisely discovering three most important EGFR drugrelated mutations from a sample in which EGFR-mutated cells only account for a small percentage of whole cell population. The microfluidic chip is capable of discovering not only the existence of specific EGFR multi-mutations,but also other valuable single-cell-level information: on which specific cells the mutations occurred, or whether different mutations coexist on the same cells. This microfluidic chip constitutes a promising method to promote simple and cost-effective Sanger's sequencing to be a routine test before performing targeted cancer therapy. | Ren Li Mingxing Zhou Jine Li Zihua Wang Weikai Zhang Chunyan Yue Yan Ma Hailin Peng Zewen Wei Zhiyuan Hu | 2018 | Nano-Micro Letters2018，10，1： | 2 |
| 14 | Reflections on the Catastrophic 2020 Yangtze River Basin Flooding in Southern China显示文摘During the summer of 2020,southern China suffered from catastrophic flooding,the massive basin flood mainly occurred in the Yangtze River's middle and lower reaches.As of July 20,2020,the cumulative precipitation since the rain season started exceeded 500 mm over most of the Yangtze River Basin,reaching>1,200 mm in some areas of the lower reaches,exceeding the same period in 1998,the severest flood year in the past 60 years.Several water gauge stations at Poyang Lake and Chaohu Lake exceeded their historical record values.The water levels in the Wuhan section of the Yangtze River were among the highest ever recorded.As of July 22,2020,45.5 million people had been affected by the floods,with 142 people having died or were missing,and the direct economic losses expected to be around 116 billion RMB(~16.5 billion US dollars).However,the losses from this flood are much lower than those of previous major floods.For example,the catastrophic 1998 flooding led to 1,526 deaths and economic losses of 255 billion RMB(~36.4 billion US dollars).The reasons behind this are worthy of further study and discussion,and may be used for reference in the future and for other countries. | Ke Wei Chaojun Ouyang Hongtao Duan Yunliang Li Mingxing Chen Jiao Ma Huicong An Shu Zhou | 2020 | The Innovation2020，1，2： | 2 |
| 15 | Steric‐Repulsion‐Based Magnetically Responsive Photonic Crystals显示文摘 | Wei Luo Huiru Ma Fangzhi Mou Mingxing Zhu Jindan Yan Jianguo Guan | 2014 | Adv. Mater2014，，7： | 1 |
| 16 | Preparation of continuous alumina gel fibres by aqueous sol–gel process显示文摘 | HONGBIN TAN XIAOLING MA MINGXING FU | 2013 | Bulletin of Materials Science2013，，1： | 1 |
| 17 | Fabrication of superhydrophobic Cu surfaces with tunable regular micro and random nano-scale structures by hybrid laser texture and chemical etching显示文摘 | Changsheng Dong Yu Gu Minlin Zhong Lin Li Kursad Sezer Mingxing Ma Wenjin Liu | 2011 | Journal of Materials Processing Tech2011，，7： | 1 |
| 18 | Joint remote preparation of an arbitrary three-qubit state显示文摘 | Luo Mingxing Chen Xiubo Ma Songya | 2010 | Optics Communications2010，283，23： | 1 |
| 19 | Prokaryotic Expression, Purification, and Production of Polyclonal Antibody Against Novel Human Serum Inhibited Related Protein I (SI1)显示文摘 | Mingxing Ma Jie Ma Yinghui Shi Hong Wu Wenxiu Zhao Weiwei Huang Yang Jiao Deyong Tan | 2010 | The Protein Journal2010，，2： | 1 |
| 20 | Laser producing Fe-based composite coatings reinforced by in situ synthesized multiple carbide particles显示文摘 | Chaofeng Wu Mingxing Ma Wenjin Liu | 2008 | Materials Letters2008，，62： | 1 |
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