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| 1 | Multi-shell nanocomposites based multienzyme mimetics for efficient intracellular antioxidation显示文摘Oxidative stress is associated with many acute and chronic inflammatory diseases.Development of nanomaterial-based enzyme mimetics for reactive oxygen species(ROS)scavenging is challenging,but holds great promise for the treatment of inflammatory diseases.Herein,we report the highly ordered manganese dioxide encapsulated selenium-melanin(Se@Me@MnO_(2))nanozyme with high efficiency for intracellular antioxidation and anti-inflammation.The Se@Me@MnO_(2)nanozyme is sequentially fabricated through the radical polymerization and the in-situ oxidation-reduction.In vitro experimental results demonstrated that the Se@Me@MnO_(2) nanozyme exhibits multiple enzyme activities to scavenge ROS,including catalase(CAT),glutathione peroxidase(GPx)and superoxide dismutase(SOD).Mechanism researches illustrated that the Se core possesses GPx-like catalytic activity,the Me and the MnO_(2) possess both the SOD-like and the CAT-like activities.What’s more,due to the stable unpaired electrons existing in the nanozyme,the Se,Me and MnO_(2) provide synergistic and fast electron transfer effect to achieve the quickly scavenging of hydrogen peroxide,hydroxyl radical,and superoxide anion.Further in vivo experimental results showed that this biocompatible nanozyme exhibits cytoprotective effects by resisting ROS-mediated damage,thereby alleviating the inflammation.This multienzyme mimetics is believed to be an excellent ROS scavenger and have a good potential in clinical therapy for ROS-related diseases. | Yongjian Ai Jinzhi You Jianyi Gao Jiaping Wang Hong-bin Sun Mingyu Ding Qionglin Liang | 2021 | Nano Research2021，14，8： | 3 |
| 2 | Taking the pulse of COVID-19:a spatiotemporal perspective显示文摘The sudden outbreak of the Coronavirus disease(COVID-19)swept across the world in early 2020,triggering the lockdowns of several billion people across many countries,including China,Spain,India,the U.K.,Italy,France,Germany,Brazil,Russia,and the U.S.The transmission of the virus accelerated rapidly with the most confirmed cases in the U.S.,India,Russia,and Brazil.In response to this national and global emergency,the NSF Spatiotemporal Innovation Center brought together a taskforce of international researchers and assembled implementation strategies to rapidly respond to this crisis,for supporting research,saving lives,and protecting the health of global citizens.This perspective paper presents our collective view on the global health emergency and our effort in collecting,analyzing,and sharing relevant data on global policy and government responses,human mobility,environmental impact,socioeconomical impact;in developing research capabilities and mitigation measures with global scientists,promoting collaborative research on outbreak dynamics,and reflecting on the dynamic responses from human societies. | Chaowei Yang Dexuan Sha Qian Liu Yun Li Hai Lan Weihe Wendy Guan Tao Hu Zhenlong Li Zhiran Zhang John Hoot Thompson Zifu Wang David Wong Shiyang Ruan Manzhu Yu Douglas Richardson Luyao Zhang Ruizhi Hou You Zhoua Cheng Zhong Yifei Tian Fayez Beaini Kyla Carte Colin Flynn Wei Liu Dieter Pfoser Shuming Bao Mei Li Haoyuan Zhang Chunbo Liu Jie Jiang Shihong Du Liang Zhao Mingyue Lu Lin Li Huan Zhou Andrew Ding | 2020 | International Journal of Digital Earth2020，13，10： | 2 |
| 3 | Super-conductive silver nanoparticles functioned three-dimensional CuxO foams as a high-pseudocapacitive electrode for flexible asymmetric supercapacitors显示文摘Copper oxide has aroused great concern in energy storage fields due to its properties of high theoretical capacitance,low cost and mild toxicity.However,its wide application still remains challenges owing to its poor electrical conductivity and unstable cycling life.Binder-free foam electrodes possess abundant porous structures and high specific surface area,which could get good contact with electrolyte.Herein,we demonstrate Ag nanoparticles decorated CuxO nanowires grown spontaneously on copper foam(CF)electrode for asymmetric supercapacitor.The skeleton structure of CF provides large amounts of active sites for the growth of CuxO nanowires.Moreover,Ag nanoparticles further decrease the internal resistance and enhance the electrochemical performance.Ag/CuxO/CF-40 electrode presents a high area specific capacitance of 1192 mF cm^(-2)at 2 mA cm^(-2)and the influence of surface capacitance-dominated process and diffusion-controlled process are discussed in detail.Besides,the energy density of the as-prepared asymmetric supercapacitor(ASC)reaches 46.32 mWh cm^(-2)at a power density of 3.00 mW cm^(-2).A 2V LED is lighted successfully by two ASC in series.This work provides a new strategy to prepare low internal resistance and binder-free flexible Ag/CuxO/CF electrode,which demonstrates a good potential application in flexible supercapacitors or other wearable electronic devices. | Hui Jiang Xuehua Yan Le Wang Xiaonong Cheng Jieyu Miao Mingyu You Yihan Zhu Jianmei Pan | 2021 | Journal of Materiomics2021，7，1： | 2 |
| 4 | Embedded Feature Selection for Multi-label Classification of Music Emotions 显示文摘 | You Mingyu Liu Jiaming Li Guozheng | 2012 | International Journal of Computational Intelligence Systems2012，5，4： | 1 |
| 5 | A Robust Multimodal Approach for Emotion Recognition显示文摘 | Song Mingli You Mingyu Li Na | 2008 | Neurocomputing2008，71，1012： | 1 |
| 6 | Synergistic lubricating effect of graphene/ionic liquid composite material used as an additive显示文摘We prepared a graphene/ionic liquid(G/IL)composite material by the hybridization of G and an IL for use as a lubricating oil additive.The friction coefficient and wear volume of a base oil containing 0.04 wt%of the G/IL composite was reduced by 45%and 90%,respectively.Furthermore,the base oil containing the G/IL composite exhibited better lubricating properties than the base oil containing G,IL,or a mixture of IL and G at the same mass fraction.A synergistic lubrication mechanism was also revealed.The G/IL composite was adsorbed and deposited on the wear surface,forming a more ordered protective film and a unique tribochemical reaction film during rubbing.Therefore,the G/IL composite exhibited the synergistic lubricating effects of G and IL,which significantly improved the lubricating performance of the base oil.This study also suggested a way to limit the out-of-plane puckering of G at the macroscale. | Lincong LIU Ming ZHOU Youtang MO Pengpeng BAI Qilin WEI Long JIN Shengli YOU Mingyue WANG Liangchuan LI Xin CHEN Xiao LI Yu TIAN | 2021 | Friction2021，9，6： | 1 |
| 7 | Optimizing soil dissolved organic matter extraction by grey relational analysis显示文摘Dissolved organic matter(DOM)in soil plays an important role in the fate and transport o f contaminants.It is typically composed of many compounds,but the effect of different extraction factors on the abundance of different DOM components is unknown.In this study,DOM was extracted from three soils(paddy field,vegetable field and forest soils)with various extraction time,liquid to solid ratios(LSRs).extractant types,and extractant concentrations.The LSR had a significant effect on DOM content,which increased by 0.5-4.0 times among the three soils when LSR increased from 2:1 to 10:1(P<0.05).Dissolved organic matter content increased by 4%-53%when extraction time increased from 10 to 300 min(P<0.05).Extractant concentration had different effects on DOM content depending on the extractant.Higher concentrations of KC1 promoted DOM extraction,while higher concentrations o f KH2PO4 inhibited DOM extraction.Therefore,grey relational analysis was used to further quantitatively evaluate the effect of extraction time,LSR,and extractant concentration on DOM,using KC1 as an extractant.For the paddy field and forest soils,the impact of these three factors on DOM extraction efficiency was in the following order:KC1 concentration>LSR>extraction time.However,the effect was different for the vegetable field soil:LSR>extraction time>KCI concentration.Taking all these factors into account,1.50 mol L^-1 KC1 and an LSR of 10:1 with a shaking time of 300 min was recommended as the most appropriate method for soil DOM extraction. | Wenming XIE You MA Shijun LI Shanshan ZHANG Lin RUAN Mingyue YANG Weiming SHI Hailin ZHANG Limin ZHANG | 2020 | Pedosphere2020，30，5： | 1 |
| 8 | Tripotassium citrate monohydrate derived carbon nanosheets as a competent assistant to manganese dioxide with remarkable performance in the supercapacitor显示文摘Production cost,capacitance,and electrode materials safety are the key factors to be concerned about for supercapacitors.In this work,a type of carbon nanosheets was produced through the carbonization of tripotassium citrate monohydrate and nitric acidification.Subsequently,a well-designed manganese dioxide/carbon nanosheets composite was synthesized through hydrothermal treating.The carbon nanosheets served as the substrate for growing the manganese dioxide,regulating its distribution,and preventing it from inhomogeneous dimensions and severe agglomeration.Many manganese dioxide nanosheets grew vertically on the numerous functional groups generated on the surface of the carbon nanosheets during acidification.The synergistic combination of carbon nanosheets and manganese dioxide tailors the electrochemical performance of the composite,which benefits from the excellent conductivity and stability of carbon nanosheets.The carbon nanosheets derived from tripotassium citrate monohydrate are conducive to the remarkable performance of manganese dioxide/carbon nanosheets electrode.Finally,an asymmetric supercapacitor with active carbon as the cathode and manganese dioxide/carbon nanosheets as the anode was assembled,achieving an outstanding energy density of 54.68 Wh·kg^(−1) and remarkable power density of 6399.2 W·kg^(−1) superior to conventional lead-acid batteries.After 10000 charge-discharge cycles,the device retained 75.3%of the initial capacitance,showing good cycle stability.Two assembled asymmetric supercapacitors in series charged for 3 min could power a yellow light emitting diode with an operating voltage of 2 V for 2 min.This study may provide valuable insights for applying carbon materials and manganese dioxide in the energy storage field. | Wenjing Zhang Xiaoxue Yuan Xuehua Yan Mingyu You Hui Jiang Jieyu Miao Yanli Li Wending Zhou Yihan Zhu Xiaonong Cheng | 2022 | Frontiers of Chemical Science and Engineering2022，16，3： | 0 |
| 9 | Effectiveness of an ocular adhesive polyhedral oligomeric silsesquioxane hybrid thermo-responsive FK506 hydrogel in a murine model of dry eye显示文摘Dry eye is a common ocular disease that results in discomfort and impaired vision,impacting an individual’s quality of life.A great number of drugs administered in eye drops to treat dry eye are poorly soluble in water and are rapidly eliminated from the ocular surface,which limits their therapeutic effects.Therefore,it is imperative to design a novel drug delivery system that not only improves the water solubility of the drug but also prolongs its retention time on the ocular surface.Herein,we develop a copolymer from mono-functional POSS,PEG,and PPG(MPOSS-PEG-PPG,MPEP)that exhibits temperature-sensitive sol-gel transition behavior.This thermo-responsive hydrogel improves the water solubility of FK506 and simultaneously provides a mucoadhesive,long-acting ocular delivery system.In addition,the FK506-loaded POSS hydrogel possesses good biocompatibility and significantly improves adhesion to the ocular surface.In comparison with other FK506 formulations and the PEG-PPG-FK506(F127-FK506)hydrogel,this novel MPOSS-PEG-PPG-FK506(MPEP-FK506)hydrogel is a more effective treatment of dry eye in the murine dry eye model.Therefore,delivery of FK506 in this POSS hydrogel has the potential to prolong drug retention time on the ocular surface,which will improve its therapeutic efficacy in the management of dry eye. | Yi Han Lu Jiang Huihui Shi Chenfang Xu Minting Liu Qingjian Li Lan Zheng Hong Chi Mingyue Wang Zuguo Liu Mingliang You Xian Jun Loh Yun-Long Wu Zibiao Li Cheng Li | 2022 | Bioactive Materials2022，7，3： | 0 |
| 10 | Improved Soft Cancellation Decoding of Polar Codes显示文摘The soft cancellation decoding of polar codes achieves a better performance than the belief propagation decoding with lower computational time and space complexities.However,because the soft cancellation decoding is based on the successive cancellation decoding,the decoding efficiency and performance with finite-length blocks can be further improved.Exploiting the idea of the successive cancellation list decoding,the soft cancellation decoding can be improved in two aspects:one is by adding branch decoding to the error-prone information bits to increase the accuracy of the soft information,and the other is through using partial iterative decoding to reduce the time and computational complexities.Compared with the original method,the improved soft cancellation decoding makes progress in the error correction performance,increasing the decoding efficiency and reducing the computational complexity,at the cost of a small increase of space complexity. | Mingyue You Zhifeng Ma | 2020 | Journal of Beijing Institute of Technology2020，29，3： | 0 |
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