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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | The in vivo and in vitro effects of chicken interferon on infectious bursal disease virus and New castle disease virus infection 显示文摘 | Mo C W Cao Y C Lim B L | 2001 | Avian Diseases2001，5，： | 1 |
| 3 | Polyphasic study of the spatial distribution of microorganisms in Mexican pozol, a fermented maize dough demonsWates the need for cultivation-independent methods to investigate traditional fermentations 显示文摘 | AMPE F OMAR B N MO IZAN C | 1999 | Applied Environmental Microbiology1999，65，： | 1 |
| 4 | The in vivo and in vitro effects of chicken interferon a on infectious bursal disease virus and Newcastle disease virus infection显示文摘 | Mo C W Cao Y C Lim B L | 2001 | Avian Diseases2001，45，2： | 1 |
| 5 | A genome-wide association study identifies common variants influencing serum uric acid concentrations in a Chinese population显示文摘 | YANG B MO Z WU C | 2014 | BMC Med Genomics2014，7，： | 1 |
| 6 | The in vivo and in vitro effects of chicken interferon α on infectious bursal disease virus and Newcastle disease virus infection显示文摘 | Mo C W Cao Y C Lim B L | 2001 | Avian Diseases2001，45，： | 1 |
| 7 | Complete genomesequence of two Chinese virulent avian coronavirus in-fectious bronchitis virus variants 显示文摘 | Mo M L Huang B C Wei P | 2012 | Journal of Virol-ogy2012，86，10： | 1 |
| 8 | The in vivo and in vitro effects of chicken interferon α on infectious bursal disease virus and Newcastle disease virus infection显示文摘 | Mo C W Can Y C Lim B L | 2001 | Avian Diseases2001，45，： | 1 |
| 9 | Nickel-catalyzed propylene dimerization in organochloroaluminate ionic liq uids: control of the isomerization reaction显示文摘 | SOUZA R F D LEAL B C MO D S | 2007 | J Mol Catal A: Chem2007，272，12： | 1 |
| 10 | Recurrent retrovi- ral vector integration at the Mdsl/Evil locus in nonhuman pri- mate hematopoietic cells 显示文摘 | Calmels B Ferguson C Laukkanen MO | 2005 | Blood2005，106，7： | 1 |
| 11 | Outcomes of posterior wall fractures of the acetabulum treated nonoperatively after diagnostic screening with dynamic stress examination under anesthesia显示文摘 | Grimshaw C S Moed B R | 2010 | J Bone Joint Surg Am2010，92，17： | 1 |
| 12 | Li/Ca ratios of ostracod shells as paleoenvironmental indicator at Lake Qinghai, NE Tibetan Plateau显示文摘 | Ren S C Zhu Z J Mo J B etal | 2010 | Geochimica et Cosmochimica Acta2010，74，： | 1 |
| 13 | Studies of the isoprenoid mediated inhibition of mevalonate synthesis applied to cancer chemotherapy and chemoprevention显示文摘 | Mo H B Elson C E | 2004 | Exp Biol Med2004，229，： | 1 |
| 14 | Psoralenoside and isopsoralenoside, two new benzofuran glycosidesfrom Psoralea corylifolia 显示文摘 | Qiao C F Han Q B Mo S F | 2006 | Chem Pharm Bull2006，54，5： | 1 |
| 15 | Identification of multivesicular bodies as prevacuolar compartments in nicotiana tabacum BY-2 Cells显示文摘 | Tse Y C Mo B X Hillmer S | 2004 | The Plant Cell2004，16，： | 1 |
| 16 | CCN1 enables Fas ligand-induced apoptosis in cardiomyoblast H9c2 ceils by disrupting caspase inhibitor XIAP 显示文摘 | Su B C Mo F E | 2014 | Cell Signal2014，26，6： | 1 |
| 17 | A genome-wide association study immutifies common variants influencing serum uric caid concentrations in s chinese population显示文摘 | Yang B Mo Z Wu C | 2014 | BMC Med Genomics2014，7，： | 1 |
| 18 | Fresh and hardened properties of seE-consolidating fiber reinforced concrete 显示文摘 | Dhonde H B Mo Y L Hsu T T C | 2007 | ACI Materials Journal2007，104，5： | 1 |
| 19 | An LVDT-based self-actua- ting displacement transducer显示文摘 | WU S T MO S C WU B S | 2008 | Sensors and Actuators A : Physical2008，141，2： | 1 |
| 20 | Electrical and mechanical properties of carbon nanotube reinforced copper nanocomposites fabricated by electroless deposition process显示文摘 | Daoush W M Lim B K Mo C B | | 0，，： | 1 |
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