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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Nitrogen availability in disturbed,rehabilitated and mature forests of tropical China显示文摘 | MO J M BROWN S PENG S L | 2003 | Forest Ecology and Management2003，175，3： | 1 |
| 3 | Sliding Tribological Behavior of A1CrNCoating显示文摘 | Mo J L Zhu M H | 2008 | Tribology International2008，41，12： | 1 |
| 4 | 显示文摘 | Cai W L Mo C M | 1999 | Appl Phys Lett1999，74，20： | 1 |
| 5 | Predicting the ther mal conductivity of multiple carbon fillers in polypropylene- based resins 显示文摘 | Gaxiola D L Keith J M Mo Na | 2011 | J Compos Mater2011，45，12： | 1 |
| 6 | Heterometallic coordination polymers generated from tripodal metalloligands显示文摘 | Li D J Mo L Q Wang Q M | 2011 | Inorganic Chemistry Communications2011，14，7： | 1 |
| 7 | 2D and 3D meso-scale finite element models for ravelling analysis of porous asphalt concrete显示文摘 | MO L T HUURMAN M WU S P | 2008 | Finite Elements in Analysis and Design2008，，44： | 1 |
| 8 | Preparation and photoluminescence of alumina membranes with ordered pore arrays 显示文摘 | Su Y Cai W L Mo C M | 1999 | Appl Phys Lett1999，74，20： | 1 |
| 9 | Preparation and photo-luminescence of alumina membranes with ordered pore arrays 显示文摘 | DU Y CM W L MO C M | 1999 | A P L1999，74，20： | 1 |
| 10 | Cyr61,a product of a growth factor-inducible immediate-early gene,promotes cell proliferation migration and adhesion显示文摘 | Kireeva M L Mo F E Yang J P | 1996 | Mol Cell Biol1996，16，4： | 1 |
| 11 | 显示文摘 | Zhang L D Mo C M | 1995 | Nanostructured Materials1995，6，58： | 1 |
| 12 | Preparation and photoluminescence of alumina membranes with ordered pore arrays显示文摘 | Du Y Cai W L Mo C M | 1999 | Applied Physics Letters1999，74，： | 1 |
| 13 | The preparation and characterization of novel charged polyacrylonitrile/PES-C blend membranes used for ultrafiltration显示文摘 | WANG M WU L MO J | 2006 | J Membr Sci2006，274，12： | 1 |
| 14 | The influence of heat treatment on electroless-nickel coated fibre (ENCF) on the mechanical properties and EMI shielding of ENCF reinforced ABS polymeric composites显示文摘 | Huang C Y Mo W W Roan M L | 2004 | Surface and Coatings Technology2004，184，23： | 1 |
| 15 | Effects of calcination condition on expansion property of MgO-type expansive agent used in cement-based materials 显示文摘 | Mo L W Deng M Tang M S | 2010 | Cement and Concrete Research2010，40，： | 1 |
| 16 | Preparation and photoluminescence of alumina membranes with ordered pore arrays 显示文摘 | Du Y Cai W L Mo C M | 2001 | J Phys Condens Matter2001，13，： | 1 |
| 17 | Characterization of a neutral serine protease and its full-length cDNA from the nematode-trapping fungus Arthrobotrys oligospora显示文摘 | ZHAO M L MO M H ZHANG K Q | 2004 | My-cologia2004，96，1： | 1 |
| 18 | Complete genomesequence of two Chinese virulent avian coronavirus in-fectious bronchitis virus variants 显示文摘 | Mo M L Huang B C Wei P | 2012 | Journal of Virol-ogy2012，86，10： | 1 |
| 19 | 显示文摘 | Wang M Wu L G Mo J X | 2006 | Journal of Membrane Sci- ence2006，274，12： | 1 |
| 20 | Diagnostic and therapentic interventions in post laparoscopic cholecystectomy biliary complications显示文摘 | YAU M P TSAI C C MO L R | 1991 | Hepato Gastroenterol1991，40，： | 1 |
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